Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PECAM1 IDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEK7 IDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZHX1 IDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZHX1 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FOXO6 IDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25648147
IDH1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SERPINH1 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IDH1 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DLST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 21191025
FOXO1 IDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25648147
FOXO3 IDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25648147
FOXO4 IDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25648147
PRKACA IDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IDH1 SERPINH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SREBF2 IDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12923220
IDH1 TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
FOXO1 SKP2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
IDH1 IDH3B â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
IDH1 IDH3G â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
FOXO1 PRKACA â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TP53 FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18615633 11062252 22796152
FOXO1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16670091 12414908 17317207
SREBF1 IDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23011765 12923220
TP53 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15059920 27692180
SREBF1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787385 22735681
IDH1 S100A12 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
IDH3B IDH3G â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
TP53 FHL2 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
IDH3A IDH3G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SKP2 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
FOXO1 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24478438 16492665 18202130 20868688 22511764
SKP2 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15340381 17522590 15147722 17646672 12820959 15668399 11516665 15071497 15688063
IDH3B IDH3A â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 14681455 33961781 31515270 10601238 14555658 26186194 16713569 28514442
PRKACA SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16381800
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785