DCUN1D2
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19617556
0812528106
|
DCUN1D2
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19617556
0812528106
|
UBE2V1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213148
11057907
|
DCUN1D2
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19617556
0812528106
|
DCUN1D2
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19617556
0812528106
|
UBE2M
|
CUL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17439941
|
DCUN1D2
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19617556
0812528106
|
CUL1
|
UBE2M
|
â—¼ NEDDYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17914462
6175264
|
DCUN1D2
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19617556
0812528106
|
CUL4B
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CUL4A
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
CUL3
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22709582
|
CUL1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
CAND1
|
CUL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CUL3
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21145461
26344197
|
CUL3
|
UBE2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
CAND1
|
CUL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21249194
31253590
12504025
21145461
22405651
|
CUL4A
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17079684
21145461
32235678
|
CUL2
|
DCUN1D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
CAND1
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
CUL4A
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17041588
31973889
23555860
18593899
33961781
16964240
21145461
30945288
32140073
|
CAND1
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31973889
28225217
26496610
25435324
12504026
12609982
21145461
34026424
|
RBX1
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33969670
24292684
12481031
25189618
12609982
26496610
30349055
27113764
29499938
19250909
22038470
34026424
28446751
31973889
23238014
33961781
33504946
30945288
32140073
|
CAND1
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29499133
18826954
12504025
15537541
12504026
30349055
12609982
|
RBX1
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19327355
17183367
12149480
15448697
10230407
12481031
29547696
32296183
11861641
15601820
30349055
22405651
25540389
10579999
19250909
21822215
21778237
29958295
22863883
33961781
33504946
28591624
17132228
|
RBX1
|
CUL4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
16189514
15448697
10230407
12481031
17452440
22474075
11861641
18593899
30349055
19295130
22405651
33759138
30352932
27113764
26976604
27203177
26990986
19250909
27203182
31973889
32235678
29958295
22863883
33961781
33504946
19287380
30945288
32140073
|
CAND1
|
RBX1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
CUL4A
|
CAND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
21249194
22474075
12504025
15448697
18606781
31973889
12609982
27203177
12504026
19295130
16964240
21145461
22405651
|
CUL2
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
CAND1
|
CUL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21249194
21778237
12609982
12504026
18173839
22405651
|
CUL3
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
CAND1
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17079684
17290223
12504025
25435324
12504026
12609982
17439941
21145461
22474075
23019411
28715492
22767593
17438373
12706828
23453757
22013077
18173839
22405651
16036220
29499133
21249194
18826954
21169563
15537541
21778237
27542266
29103612
16861300
12684064
|
CAND1
|
CUL1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
12504025
12504026
15537541
|
CUL3
|
CAND1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21249194
16449638
22013077
12609982
21145461
22405651
26286618
|
CUL5
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
UBE2N
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
31638574
14517261
18678647
25527291
27173435
30097011
33619271
27182664
29537486
|
CAND1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
CAND1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
UBA1
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
DCUN1D2
|
UBE2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
CUL1
|
DCUN1D2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
RBX1
|
UBE2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
CAND1
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
UBE2N
|
UBE2V1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
CUL3
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
19818716
15448697
12481031
11861641
30349055
25270598
20027226
22405651
26100637
19256485
11311237
19250909
25278611
26286618
20865015
15601839
19617556
29958295
33504946
12684064
24145166
|
CUL1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17290223
5219620
|
CAND1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
CUL5
|
RBX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31253590
18805092
10230407
11861641
14564014
25912140
19250909
30349055
15574593
22405651
|
CAND1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
DCUN1D1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
CUL4B
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CUL5
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CUL1
|
UBE2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
DCUN1D1
|
UBE2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
CUL4A
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
RBX1
|
CUL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16189514
12504025
20832730
15448697
10230407
19933270
12840033
12904573
18723677
12504026
12481031
17452440
12609982
26540345
27697867
22474075
11245432
22767593
28152074
22822056
19245792
12706828
11861641
20399188
10748083
11956208
11483504
27910872
16759355
30349055
10713156
11027288
21765416
20638939
22405651
23770852
19942853
10648623
12565873
18826954
18805092
32145688
21169563
27591266
22660580
11961546
32313199
15361859
19250909
29863914
24949976
10230406
32726803
30653357
32015321
33692209
16123592
34237211
29958295
29103612
33961781
33504946
12684064
26725323
26344197
|
CUL3
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
CUL2
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CUL1
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CAND1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RBX1
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
22466611
24127601
23973375
22466612
20541997
22466610
23906714
16751180
22902626
|
UBE2M
|
CUL4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
26460955
25314029
18206966
23201271
26906416
19250909
25531226
26344709
|
CUL1
|
RBX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RBX1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
RBX1
|
CAND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
Reactome
|
19748355
12504025
18805092
15688063
18851830
23453757
15537541
23535663
11961546
26632597
21463634
12504026
12609982
23535662
21863050
|
RBX1
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL3
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11583996
11900249
12648680
12820959
14744430
15340381
15459660
15688063
15703371
15760909
16498403
16547521
16697054
17312394
17884153
18545270
18931676
19090789
19427028
19560419
19622404
19686080
19809470
19818716
19847258
20006983
20531300
20599425
23030059
23377657
23845861
23850759
27984721
9242610
|
RBX1
|
CUL2
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
10973499
11900249
12351678
12648680
12820959
15340381
15459660
15652751
15688063
15703371
15721254
16697054
17884153
18420585
18931676
18985005
19622404
19622774
19686080
19809470
19847258
|
RBX1
|
CUL1
|
â—¼ SHARES_COMPLEX
|
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
RBX1
|
CUL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
76.0
|
1.0
|
ACSN
|
10023660
10671552
11348595
11900249
11955436
11967263
12051714
12648680
12820959
14536078
15001769
15071497
15147722
15340381
15459660
15489953
15688063
1570337
15703371
16039586
16469695
16697054
16713974
16940750
17053147
17143292
17652783
17884153
17928543
17936032
18196958
18636226
18787170
18805092
18931676
19143635
19150432
19250909
19258535
19270156
19352404
19366350
19411070
19557001
19576224
19597341
19619488
19622404
19686080
19751508
19797085
19809470
19836308
19847258
19849719
20006983
20211143
20558317
20705860
20832730
20843316
20976471
21411632
22270359
22682247
22730322
23343194
23732914
24023259
25730849
26159692
26885856
7542250
7641885
8666229
9694792
|
RBX1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
154.0
|
1.0
|
Omnipath
|
17053147
12684064
20638939
11967263
19797085
19258535
26540345
18826954
15071497
15448697
21765416
25730849
10230406
23343194
21169563
22270359
19250909
23732914
11359933
12051714
20006983
15361859
10748083
19352404
22682247
18787170
12504025
18636226
16469695
15459660
20211143
10535940
15001769
26725323
19411070
11861641
26159692
16697054
1570337
19751508
22822056
11348595
7542250
7641885
19849719
16759355
12820959
17452440
19622404
15703371
10648623
19245792
23331499
9694792
19150432
23180781
19597341
16189514
22474075
18988627
22767593
17143292
24949976
10713156
23770852
22405651
19942853
18196958
20399188
16713974
26192618
11027288
17884153
19933270
22730322
21411632
11961546
17936032
19809470
15147722
19270156
19576224
11483504
20976471
12504026
24023259
12840033
15340381
12904573
20558317
11900249
14536078
19686080
12565873
18805092
15489953
19557001
26885856
17652783
12481031
20843316
11955436
21071413
16039586
11956208
20705860
8666229
17928543
10023660
19836308
16940750
12706828
19143635
15688063
10671552
16123592
19366350
19847258
12417738
11245432
20832730
12648680
12609982
19619488
10230407
18931676
|
UBE2N
|
UBE2V1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
15492226
29662619
10089880
1551980
11057907
16129784
25260751
15147900
22367539
18082144
18678647
26101372
20551964
16307917
17709375
19549727
18029035
21460221
24145445
16215985
20613989
25548215
|
UBE2M
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
26460955
25314029
18206966
23201271
26906416
19250909
25531226
26344709
|
CAND1
|
CUL4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
17145710
18606781
19295130
22405651
27203177
17079684
21249194
19231300
12504026
21145461
12504025
22474075
12609982
16964240
15448697
|
UBE2F
|
DCUN1D1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
25314029
18206966
21940857
23201271
26906416
19250909
25531226
27030794
|
UBE2M
|
CUL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
16647857
19617556
18826954
25349211
25314029
18206966
21940857
23201271
26906416
19250909
25531226
21863050
|
UBE2M
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
24949976
10713156
17914462
21247897
18805092
21946088
19245792
18826954
|
CAND1
|
CUL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
45.0
|
1.0
|
Omnipath
|
17145710
12684064
25435324
36076154
23019411
18826954
17290223
17438373
21169563
27542266
16036220
21145461
21778237
22474075
22767593
16861300
18173839
12504026
12504025
12706828
22405651
21249194
23453757
22013077
17439941
12609982
15537541
|
UBE2M
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
19617556
18826954
25349211
23912815
25314029
18206966
21940857
23201271
26906416
19250909
30610225
25531226
|