FADD
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16227629
23131831
|
CREB1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7721872
12658356
|
E2F4
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15510213
18319725
|
AKR7A3
|
AKR7A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
ATXN3
|
AKR7A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FOS
|
HPGDS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8617242
8206948
|
JUN
|
HPGDS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8617242
8206948
|
LRRK2
|
E2F4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
E2F4
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
|
JUN
|
UGT2B15
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19487245
|
JUN
|
CYP3A4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14742674
|
NFE2L2
|
CBR3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20806931
22001310
|
NFE2L2
|
GSTK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17077087
22521774
|
NFE2L2
|
EPHX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16428448
24704207
|
NFE2L2
|
UGT1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21801714
19719968
|
NFE2L2
|
CYP2E1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19671018
23400918
|
UGT1A10
|
UGT1A7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
UGT1A7
|
UGT1A9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
CDK2
|
E2F4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25852190
|
LRRK2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
VCAM1
|
GSTP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22623428
19738201
|
CTR9
|
DISC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31413325
29961565
|
GSTM2
|
GSTM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CBR3
|
CBR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26496610
|
GSTA1
|
GSTA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
PCNA
|
CCNB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
7903056
33961781
8101826
|
GSTM3
|
GSTM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
1530570
26186194
33961781
|
CREB1
|
JUN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
2138276
25609649
|
GSTM3
|
GSTM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
|
GSTM2
|
GSTM5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
GSTM5
|
GSTM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
GSTA2
|
GSTA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
25416956
25910212
33961781
26186194
|
GSTA2
|
GSTA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
GSTM4
|
GSTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GSTM2
|
GSTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
GSTM2
|
GSTM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BIRC2
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
GSTA2
|
GSTA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
GSTM2
|
GSTM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
6500576
33961781
12192076
|
GSTM3
|
GSTM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
AKR7A2
|
AKR7A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
LEO1
|
CTR9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18469135
20178742
22532828
26496610
15632063
16024656
24981860
20305087
27173435
22939629
26344197
|
E2F4
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17671431
|
GSTM3
|
GSTM5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
|
E2F4
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15510213
|
JUN
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9468519
16271621
|
NFE2L2
|
VCAM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15998244
16339837
12370194
|
TRADD
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8943045
12887920
|
GSTM3
|
GSTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
CCNB1
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
20733051
28514442
9891079
7799941
8397207
25852190
26496610
33961781
26186194
23602568
10995390
23455922
30674583
18471975
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
TRADD
|
FADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24686082
32296183
12107169
12796506
8681376
21724995
12911633
23955153
11112409
16919273
8565075
30561431
10911999
|
MSH6
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
16189514
15225546
24958773
21725088
26496610
11005803
11274057
22939629
22232658
26344197
|
GSTM2
|
GSTM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
MSH6
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CCNB1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
FOS
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CTR9
|
LEO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
E2F4
|
CDK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17531812
22447046
|
TRADD
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
FADD
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
BIRC2
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19223549
12867425
20301198
|
PCNA
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
20713735
20154325
22118461
11274057
11441019
11005803
18326858
17984070
11809883
16188885
16143102
|
JUN
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22550165
19940138
1352831
15205327
23078099
|
FOS
|
GSTP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8206948
2112105
8702826
|
NFE2L2
|
HPGDS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19282378
22676582
12716947
14960151
15655294
15870285
15654768
15155840
12023900
|
E2F4
|
CCNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17531812
15855772
22508987
|
FADD
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
FADD
|
TRADD
|
â—¼ SHARES_COMPLEX
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TRADD
|
FADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
8565075
14744432
12911633
21760970
9430228
21724995
21741934
12796506
10911999
20203691
23955153
32296183
12107169
11112409
11464215
8681376
12887920
24686082
21183682
18545270
|
VCAM1
|
ITGA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22623428
19738201
11751331
|
JUN
|
FOS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
JUN
|
FOS
|
â—¼ PROTEIN_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
10606235
11274345
11274400
14673140
15067049
16393692
16394015
17439715
18222063
18754863
19667062
19846528
21385848
21790308
22381618
22634314
22723415
23430059
26587781
8545107
9064320
|
CREB1
|
JUN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
10471787
8647095
10403485
2140898
|
JUN
|
FOS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
2513130
14561487
8617996
8934539
19255142
9217081
12760745
2498806
10521486
8597411
10858536
12392213
9819441
1380150
23562910
1944274
9867253
9571041
1900040
2511006
14684847
15467742
12231642
11950097
|
FOS
|
JUN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
20498278
16714286
21675959
25609649
23602568
9872330
20102225
8380166
18848838
18535250
2516828
8397339
15867431
18172215
9346889
10779323
9732876
16928824
26496610
15994313
22719067
24029232
16511568
20195357
11053448
20936779
26186194
18619508
20511396
16008525
10488148
21199371
8617242
17440114
16055710
15319445
11090181
9160889
23661758
1631061
15718494
11431474
31515488
8440710
7816143
20410304
34671206
|
JUN
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
2138276
1827203
18641343
8290251
|
NDUFA4
|
NDUFS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA4
|
NDUFS3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NFE2L2
|
GSTA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22459801
16551619
17077087
24024136
|
BIRC2
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
35941131
22179575
22848449
23313255
24098568
34876703
16282325
20385093
22435550
18178551
19910467
|