Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CASP3 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11248093
NEO1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18583991
FYN TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
PIK3R1 IGF1R â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6730400 7589433
PIK3R1 INSR â—¼   PROXIMITY 2.0 0.8 intact 6731120 10500481
INSR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8567177 8385099
NTN1 NEO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804008105 18719102
NEO1 UNC5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804008105 18719102
TGOLN2 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
UNC5B PPP2R3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15729359
IGF1R PIK3R1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
FGFR1 PIK3R1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
LRIQ1 UNC5B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIQ1 EPHA7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIQ1 FGFR4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIQ1 FYN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA7 EPHA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 FLRT3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EPHA4 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16365308 18790757
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EPHA4 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12084815 31413325 16189514 16713569
NEO1 NTN1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EPHA8 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10498895 16189514 16713569
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
INSR PIK3R1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
PIK3CA ALK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11280786 11110708 18097461
PIK3R1 ALK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11280786 11110708 18097461
FYN DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
FGFR1 FLRT3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20421966 16872596 14688794
NTN1 FYN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
PPP2CB PPP2R1B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
DCC NTN1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
FYN AGAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16841086 18469807 26001218
CASP3 DCC â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11248093 16158190 15310786 9796814
DAPK1 UNC5B â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172648 21172653 22920895
DAPK1 NTN1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172653 22920895
DAPK1 PPP2CB â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12598906 17703233 18582460 19543238 20495383 21172648 21172653
DAPK1 UNC5B â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172648 21172653 22920895
DAPK1 NTN1 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172653 22920895
DAPK1 PPP2CB â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12598906 17703233 18582460 19543238 20495383 21172648 21172653
UNC5B DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15729359 21172653
NTN1 DCC â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
NTN1 DCC â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
FYN DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15557120 21849478
NTN1 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19721007 8861902 26190107 9950216 11239160 25881791 10399920 12810718
EPHA4 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12084815 23331499 16713569
PPP2CA EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
FGFR1 PIK3CA â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17505008 18757403 21666749 11689702 21711248 11739186 21160078 14534538 15448205
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FGFR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 18412956 25241761 15117958
FGFR4 PIK3R1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR4 PIK3CA â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17505008 18757403 21666749 11689702 21711248 11739186 21160078 14534538 15448205
NRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR4 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
FLT4 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
FYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8294442 8394019 7515100 17570479 16713569 7520528 1652056
IGF1R PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8603569 17496910 25241761 8697095 7642582 17570479 18595745 7589433
INSR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 15629149 17389395 8276809 18083107 11796522 8385099 20068231 8567177 16497976 15592455 17570479 9593725 7589433 14729945 17016520 10500481
KRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NTN1 NEO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12636918 28245592 8861902
NRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8052307 7820549 9150145 8665852 21779497
NTN1 UNC5B â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172653 22920895
NTN1 UNC5B â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172653 22920895
NTN1 UNC5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23599441 26840727 9126742
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
UNC5B PPP2CB â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12598906 17703233 18582460 19543238 20495383 21172648 21172653
UNC5B PPP2CB â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12598906 17703233 18582460 19543238 20495383 21172648 21172653