FUS
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18471544
|
PPP1R15A
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PSMD4
|
PSMC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
ATF4
|
FUS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18471544
|
DCTN3
|
ACTR10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15473859
15738427
|
PDGFB
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9546424
9739761
|
ELK1
|
PDGFB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9690620
|
HSPA5
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ITGB3
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
ESR1
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24641954
20623181
|
THBS3
|
CALR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TUBB
|
CALR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
AP2S1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
ESR1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23403292
24998469
|
CREBBP
|
TCF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9774110
9388250
|
CREBBP
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8941362
|
TUBB
|
TAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TAB1
|
TUBB2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
EGF
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7565730
8617750
|
NRAS
|
EGF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
MAP2K1
|
ELK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10716983
10997882
|
GDF9
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
SEC24A
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790530
2391366
|
HLA-DRA
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
SEC24A
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11790530
2391366
|
AHNAK2
|
ACTR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DCTN3
|
ACTR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15473859
15738427
|
ERBB3
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
GNA11
|
PLCB2
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
CHRM1
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14976183
12200418
|
NRG1
|
ERBB3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10768865
23365119
|
DCTN3
|
CAPZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15473859
15738427
|
PEX14
|
TRAP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19197237
7231031
|
TCF7L2
|
NOS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16849547
11935128
|
TCF7L2
|
TCF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15473860
10489374
|
SMCR8
|
C9orf72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
ACTR1A
|
DCTN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
ATF4
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
C9orf72
|
SMCR8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
27103069
|
C9orf72
|
SMCR8
|
â—¼ GTPASE_REACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
27103069
|
ITGA5
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
ICAM1
|
PAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PAK1
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16452229
12374744
|
WNT7A
|
CALR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PSMD9
|
PSMD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
RAC2
|
ELMO2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ESR1
|
MYH14
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21182205
25604459
|
NUP155
|
NUP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
NRG1
|
EGF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
7730382
28988771
|
ACTR10
|
DCTN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
ATG13
|
C9orf72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
FLNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
21182205
19805454
25604459
|
MBL2
|
CALR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18177377
8062452
|
ESR1
|
MYL6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20308691
21182205
21217774
|
ATP6V0A2
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
NRG1
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
7514177
|
PSMC5
|
PSMD9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
ATF4
|
NFE2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
STX7
|
STX10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
NUP50
|
KIFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
MYH14
|
MYL6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
22863883
33961781
|
KATNA1
|
KATNBL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
KIF11
|
TUBB2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
NUP155
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CREBBP
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
TNNC1
|
TNNT2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
12840750
9219516
9560191
15542288
|
PINK1
|
TRAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31300519
17579517
|
ACTR1A
|
ACTR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
NDUFB11
|
NDUFB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
NDUFB11
|
NDUFB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
EXOC5
|
ARF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14662749
16713569
|
FLNA
|
DRD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11911837
12181426
10692483
11320256
|
DNAJB11
|
HSPA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
ACTR1B
|
DCTN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
AKT3
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14766748
15642728
17525161
|
NRAS
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15520807
17462920
20363321
|
NFE2L2
|
ATF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21087962
23618921
20185790
|
CSNK2B
|
STK16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ACTR1B
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
CSNK2B
|
TUBB2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RHOA
|
EZR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
35267019
15659383
|
NFE2L2
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17313370
18241676
18199529
|
NFE2L2
|
CAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22493435
|
ESR1
|
SEC61B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
NCF1
|
NCF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11893732
11796733
15657040
11258927
9083043
|
EGF
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
ERBB3
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
RHOA
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
RHOA
|
PFN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22820501
22479341
27228149
|
CDK5
|
DRD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
24391960
|
CDK5
|
CORO1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
26823173
|
HLA-DRA
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
PRKCE
|
OCLN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21545357
|
ERBB3
|
NRG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
31467278
30523157
10913256
9565587
7592681
8702572
28988771
11389077
17697999
33961781
11555649
9168115
|
LRIG1
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
16123311
|
RHOA
|
ROCK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
31871319
11350930
|
BAX
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
KATNAL1
|
KATNBL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
ACTR10
|
CAPZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
ERBB3
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
FLNA
|
ITGB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
EXOC2
|
EXOC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
22939629
27173435
26344197
|
ATP6V1A
|
ATP6V1F
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
DYNLT1
|
DYNLT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HuRI
|
32296183
|
NDUFC2
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
AP2S1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
31353312
16189514
7593184
33961781
26344197
|
KATNA1
|
KATNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
ACTR10
|
ACTR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
AP2A1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
TNNC1
|
TNNT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
ACTR3B
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
C9orf72
|
SMCR8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
KSR1
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NUP54
|
NUP93
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
NDUFB4
|
NDUFB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
NDUFA9
|
NDUFB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
ACTR10
|
ACTR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
EXOC2
|
EXOC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
NDUFA9
|
NDUFB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
COX7A2L
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PSMC5
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMC5
|
PSMD11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMD14
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMC5
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFB11
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD11
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
POLR2B
|
POLR2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12150925
18000759
19225151
21157483
17680028
19151919
19864431
26801615
15755954
19446321
19258318
19706736
12408816
19211837
11274345
19211835
19568798
|
BCL2L1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
59.0
|
1.0
|
Omnipath
|
22705850
18981409
21458670
28202514
11283018
17525735
29749471
21567405
9388232
18547146
19074440
16151013
21199865
18178565
26496610
16189514
15486085
26186194
17289999
9111042
12419244
25241761
14963330
12853473
9742125
9153240
19427863
21852238
14766748
21671007
15131699
9670005
8596636
24814347
9824152
9027312
|
PINK1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23953109
24013390
28486788
18974096
26188358
31367011
34064109
22617334
12633850
21840391
20363734
17369848
27398719
|
IL18
|
ICAM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
CALR
|
LRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
14508489
16181333
16239148
17204652
20958319
22076556
23157435
23850759
25351513
|
CALR
|
LRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
14508489
16181333
16239148
17204652
20958319
22076556
23157435
23850759
25351513
|
MTOR
|
NRF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12533512
12906785
15755954
16469695
17680028
18046414
18048642
18492954
19022819
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17517883
18372248
19203586
17277771
15718470
|
PAK1
|
MAP2K3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10661401
11062502
11385609
11907067
12885870
14764585
15536084
|
CDK5
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
20058876
17114649
12176333
12950086
19298660
19664994
12176334
15542607
19413330
23537649
19036346
19664995
21825040
11604394
|
RAC2
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9705280
23331499
10224076
|
PAK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
18521086
26944939
16778166
18755239
21893191
15178330
19205871
29548483
26554417
27003261
24505617
16452229
15193262
19557173
15642175
12374744
19465939
17604944
25447917
20179234
|
PAK1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
18593598
27542844
21371233
22105362
22981863
18668521
27169363
12876277
31416844
23331499
33789117
7873542
29551131
28225038
19595712
11435472
9351825
25794709
9416003
21248166
14993270
23701950
18940914
16129686
11948406
23162738
|
PAK1
|
ARHGEF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
22072711
17488622
14970201
19667072
19690332
29036929
24352660
28096473
20406887
18669648
|
PAK1
|
MAP2K3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7592586
11304531
15677464
11309380
14970210
|
PAK1
|
ARPC1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
28007610
20603326
14749719
25472536
|
PAK1
|
NCF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12855698
7618083
16099876
10559253
18160398
|
PAK1
|
FLNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
18598695
18088087
24278701
12198493
26009991
15024089
25472536
23246867
|
ATF4
|
PPP1R15A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19564919
23907468
12840028
31226023
|
ATF4
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11564156
9295363
25241761
|
CDK5
|
EZR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12769842
16510591
|
ROCK2
|
EZR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8522586
20737283
9456324
9287351
10970850
12778124
12045227
12802084
7579708
10047517
8527459
|
PDGFB
|
THBS3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9334164
10508235
1311092
8900172
|
NDUFS5
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB4
|
NDUFA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA9
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFA9
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA9
|
NDUFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB4
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFA9
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA9
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA9
|
NDUFC2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB4
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB11
|
NDUFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB4
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB11
|
NDUFC2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
12601012
12667446
15186778
15526035
15807660
16200211
16218961
16246152
17344420
18485875
19131594
20025615
20816094
23850759
|
NDUFB4
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB4
|
NDUFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFB4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
12601012
12667446
15186778
15526035
15807660
16200211
16218961
16246152
17344420
18485875
19131594
20025615
20816094
23850759
|
NDUFB4
|
NDUFC2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB4
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFS5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFC2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFS5
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS5
|
NDUFC2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
PINK1
|
TRAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17579517
|
NFE2L2
|
CD36
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18585365
22511637
18302760
14752028
|
CREBBP
|
NFE2L2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21196497
11683914
11154691
|
HLA-DRA
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
HLA-DQA1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
NCF1
|
RAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11145705
1660188
18347018
11090627
10455184
|
NCF1
|
NCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
NCF1
|
NCF4
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
CREBBP
|
TCF7L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
10769018
11050151
18160704
15060161
11973335
10775268
|
CREBBP
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9192902
18765668
16417649
11113179
8616895
11782371
14766010
17400812
|
NRAS
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
KSR1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8503013
19541618
15090600
11741534
1330321
17613518
11940661
18332145
7992057
8248196
15520859
|
ROCK2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11283606
15699075
8816443
11294240
8617235
|
EGF
|
RHOA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
12094222
15003992
15175028
15466195
15958574
18423981
19631971
20430953
21098712
8101258
|
ARHGEF2
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9789025
22072711
32203420
9113980
9641915
10592173
9857026
20810787
16189514
24525234
11149925
|
RHOA
|
ROCK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23109003
12727213
17673200
17446864
11350930
|
ESR1
|
EGF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10894157
15075211
20889718
8770893
19423651
|
CDK5
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
18691976
25971971
8114697
11684694
15665076
10567369
8157000
12609978
|
CDK5
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12824184
|
AP2A1
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
AP2A1
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8397411
10480952
9202021
15749704
|
ESR1
|
PSMD4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18457947
9253789
12648521
11696545
23580568
|
HLA-DRA
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
NRAS
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
ESR1
|
NRF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18048642
21486948
23892277
|
GNA11
|
PLCB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1333052
3017978
|
RAC2
|
NCF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11145705
1660188
18347018
11090627
10455184
|
NRAS
|
ERBB3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
NRG1
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10970856
16843264
7514177
7592681
23331499
8702572
7477375
11555649
9565587
16189514
26148232
9168115
9275162
10214951
17697999
|
POLR2G
|
POLR2L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
POLR2B
|
POLR2L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NRAS
|
NRG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
HLA-DQA1
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
KATNB1
|
KATNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9568719
26929214
10751153
26496610
16203747
|
KATNA1
|
KATNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9568719
26929214
10751153
26496610
16203747
|
MYL6
|
MYH14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9354661
8662509
11331307
11942626
|