CREB5
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8378084
8440710
|
CETN2
|
SUMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23751493
26151477
|
MYC
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MYC
|
ALB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17006931
8076602
|
MYC
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15197457
12420224
|
CREB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20864035
|
ATP1A3
|
SKIL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SKIL
|
TTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SKIL
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12419246
12426322
|
SUMO1
|
SRF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12788062
|
SMAD7
|
TTF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
TTF2
|
SMAD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
PRKCA
|
ATP1A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17570479
14976217
|
TTR
|
ATF4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
GNAS
|
ADCY4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9228084
21406690
|
GNAS
|
ADCY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9228084
21406690
|
CREB1
|
TGFBR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20629536
10567368
|
CREB1
|
SLC5A5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
34751390
|
PRKACA
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8657310
9660757
|
PRKACA
|
SRF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12809504
19778940
|
GNAQ
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNAQ
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNAQ
|
PLCB2
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNAQ
|
PLCB3
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB2
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB2
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB2
|
PLCB3
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
TSHR
|
HNRNPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HSPA5
|
TNIP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HSPA5
|
CNTRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CREB3L1
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15572842
15665855
|
PLCB4
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB3
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB3
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
MYC
|
CDC5L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30415952
29467282
|
CETN1
|
CETN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
MYC
|
MATR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
MYC
|
PRS6B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
DCTN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
CBWD1
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
COMD1
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PRS6B
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
HAVR2
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CETN1
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GNAQ
|
PLCB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
PEX19
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CLPB
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26186194
33961781
12927788
|
HDAC7
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
SKAP1
|
TTF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NIN
|
DCTN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
28718761
26638075
|
NINL
|
DCTN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27173435
26485645
28718761
|
NIN
|
PCM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
30217970
28718761
26638075
|
CREB5
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8440710
28514442
26186194
33961781
|
CDC5L
|
SUMO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
20467437
19596686
|
ATF2
|
CREB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
HNRNPA1
|
HNRNPA2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
TTF2
|
CDC5L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20467437
12927788
|
PLCB1
|
GNAQ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16754659
12193606
11753430
|
TTF2
|
CDC5L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12927788
|
SMAD1
|
MYC
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
15576399
22290435
22761862
|
MYC
|
PRKCG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15345217
9489489
23550155
|
MYC
|
ADCY9
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
ATP1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
MYBL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
SKIL
|
SMAD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
23154975
16442497
|
GNAS
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
|
GNAS
|
ADCY8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
GNAS
|
ADCY9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
GNAS
|
ADCY7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9228084
21406690
32196115
|
PRKCA
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8206971
7759492
|
PRKCA
|
HNRNPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7727389
|
TTF1
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9607786
7997232
9468516
|
TSHR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17891229
32698392
8188646
|
CGA
|
TSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8188646
2558651
12045258
|
CGA
|
TSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15571461
20181794
12045258
|
TSHB
|
TSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8188646
2558651
12045258
|
PAX8
|
TSHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17614769
15929662
|
ADCY9
|
GNAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP1A1
|
FXYD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
DCTN1
|
RPGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATP1A1
|
ATP1B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
PRKCA
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1661585
9436983
19176525
92095966
|
PRKACA
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1661585
15105425
92095966
|
MYC
|
HNRNPA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12747840
20010808
12695333
|
MYC
|
ATF4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12695333
23612979
|
MYC
|
HNRNPA2B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12747840
20010808
12695333
|
ATF4
|
CREB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17669268
17434604
18441292
15240803
15888447
16121183
|
GNAS
|
ADCY2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9228084
9395396
1719547
9268375
21406690
|
GNAS
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9228084
6935665
210183
17652154
2022671
21406690
32196115
|
GNAS
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9228084
9748257
9268375
21406690
|
TGFBR2
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11278251
15221015
11163210
|
PRKCA
|
SRF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12809504
19778940
21777672
16537394
|
PRKCA
|
ADCY2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8383119
8900209
9366262
7938004
9268695
|
PRKCA
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
9015864
11278470
9349568
2211670
9307019
17570479
21338571
|
PRKCA
|
PLCB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11278298
9660757
15302935
10893237
|
SRF
|
CREB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
15733869
28286024
15542842
9770464
1833716
18088355
7823924
7551568
15449318
2040600
|
CREB1
|
PRKACA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
19244110
12150772
12082174
2573431
9733829
17908236
15879576
|
CREB1
|
CGA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11518798
10341006
15637148
11014230
21986493
|
PRKACA
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
11160957
21902831
2885756
2875459
7958915
9829964
12235136
12763014
9687510
8887554
15568017
11698596
8688081
9528766
11018520
11969286
11909979
8336722
|
PRKACA
|
DUOX1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19144650
|
PRKACA
|
PLCB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
28615442
9660757
10893237
|
PRKACA
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
2847175
1847804
8132598
19144319
12529267
14741364
|
GNAQ
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11753430
1309799
12193606
16754659
8245028
8387502
1322796
1846707
|
ATF6B
|
HSPA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17522056
14973138
11256944
|
TTF1
|
TSHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10807057
8813723
8145764
7997232
15929662
7654187
7565801
|
TSHB
|
TSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
2558651
20181794
12045258
15571461
|
PAX8
|
TPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11923479
21833035
9512459
16007137
17182173
1508216
27347897
8062273
15356023
8652674
10698164
9288908
24380675
7635972
|
PAX8
|
SLC5A5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
14630715
18202153
20667985
11573135
15961562
22531031
17614769
14623893
|
PAX8
|
TG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
16179407
8813721
9288908
10807057
11069301
10871399
7737192
9845675
15718293
16613988
19010321
11463576
10499522
21833035
11453662
9882622
8869595
10698164
11325833
1508216
9396634
11786384
18437010
11145590
17614769
7635972
|
TTF1
|
SLC5A5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18682709
11573135
9328356
23594881
10401674
|
TTF1
|
TG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
21637535
8813721
7997232
1732732
17980011
11046146
10807057
10871399
11069301
9845675
16613988
18852534
10499522
11463576
15181011
11149600
9607786
8869595
10698164
1922026
11325833
1811929
1555648
7592890
9396634
7828540
1735431
7635972
18437010
17671725
19010321
|
TTF1
|
TPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11923479
8145764
17182173
21637535
10698164
1735431
1811929
15872358
7635972
|