POMC
|
MC3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1325670
6274691
|
POMC
|
OPRM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7905839
8208289
|
POMC
|
MC4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1325670
6274691
|
OXTR
|
CD81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
F2RL1
|
CD81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HRH1
|
CD81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
MC4R
|
CD81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ADCYAP1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PDZK1IP1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DRD4
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SST
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SSTR3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
F2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HTR2C
|
ATP6AP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
THRA
|
PRL
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9259323
2903439
|
C5
|
C5AR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11773063
12540846
|
PDYN
|
OPRM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7905839
8208289
|
THRA
|
THRB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
1782215
17761769
|
NMB
|
GRPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1655761
8383682
|
GHSR
|
GHRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10604470
11322507
|
GHRL
|
NPY
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12663466
11196643
|
APLNR
|
APLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8294032
9792798
|
F2RL1
|
ERGIC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
EBP
|
LRRC59
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
LRRC59
|
TMEM97
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
BIK
|
CD53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.8
|
0.8
|
HuRI
|
32296183
|
NPY2R
|
NPY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
7559383
12007534
23597562
9001438
|
GLP1R
|
CD81
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28597972
23864651
|
GRIA3
|
GLRB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GRIA3
|
GRIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
P2RX2
|
FKBP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GRIK5
|
GRIK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8288598
15583001
9466455
|
FSHR
|
FSHB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22802634
15662415
10395410
|
TAC1
|
TACR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
TAC1
|
TACR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
BIK
|
TMEM97
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
SCT
|
SCTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
POMC
|
MC2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1325670
8463333
14463577
|
GIP
|
GIPR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15655707
17715056
12627975
8795084
7589426
|
F2RL2
|
F2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
F2
|
F2RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
F2RL2
|
F2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9618465
9087410
1672265
|
GNRH1
|
GNRHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1333190
6090951
9419371
|
OXT
|
OXTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
4065330
2991279
1313946
|
PRLHR
|
PRLH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9607765
10498338
8666380
|
LHB
|
LHCGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1922095
8702611
2244890
|
PMCH
|
MCHR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10421368
11562423
10421367
|
NMUR2
|
NMU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
10899166
10894543
10887190
|
NMUR1
|
NMU
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
10899166
10894543
10811630
|
GIP
|
GIPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
GRIK2
|
GRIK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
FSHB
|
FSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
F2
|
F2RL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CSH1
|
CSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
POMC
|
MC2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12213892
9058374
905837412213892
20371771
|
POMC
|
MC3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
11024027
10493100
10358030
17702843
20371771
7774675
|
POMC
|
OPRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9686407
7624359
8624732
|
POMC
|
MC4R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
8884876
9058374
11024027
10493100
12165561
20371771
11101306
20694162
|
POMC
|
OPRM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15464143
|
CRH
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8536644
8243338
23504413
11123370
|
GIP
|
GIPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
12627975
26572091
17715056
8795084
15655707
7589426
15655705
|
NPY
|
NPY2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
1317848
3202875
7592911
7592910
6373251
6589611
10461880
|
NPY
|
NPY2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
8632753
7592910
7559383
9549761
9001438
12007534
|
PLG
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12604689
10978167
9020112
|
ADCYAP1
|
VIPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
8791009
16930633
11897681
12429744
12488235
11931347
9928018
|
ADCYAP1
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
8703026
16930633
12488235
10583729
11931347
21350482
10100920
17470806
8253796
|
F2
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10978167
1135698510978160
11356985
|
F2
|
F2RL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11356985
12732212
1135698512732210
|
TAC1
|
TACR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
12954451
7682062
9190866
8925404
11786503
7961636
11137709
10189055
7534932
23597562
|
TAC1
|
TACR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
7557266
9190866
1311270
8985159
11786503
12548712
8702757
15265501
23597562
|
FSHB
|
FSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15662415
17145710
2126341
10395410
|
SCT
|
SCTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
7612008
7782300
9440501
8579602
|
C5
|
C5AR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
9881961
11773063
9553099
15661745
10602324
1847994
|
C5
|
C5AR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12899627
11773063
|
PDYN
|
OPRM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9686407
|
PTH2R
|
PTH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
12559132
3616618
6950381
12098667
8732687
8386612
8397094
8770894
8082781
7797535
|
PTH2
|
PTH2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10854439
11602681
11861531
|
NMS
|
NMUR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
1563544915635440
29288685
15635449
|
NMU
|
NMUR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
15331768
15292653
10899166
10887190
10894543
|
NMS
|
NMUR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
15635449
29288685
|
NMU
|
NMUR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
15331768
15292653
10899166
10811630
10894543
|
PDYN
|
OPRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
9686407
9262330
1967312
7624359
8170987
17503481
7869844
|
GHRH
|
VIPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8791009
10655511
|
NMB
|
GRPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
1655761
1720612
10454496
7838118
19463875
21729729
|
GRP
|
GRPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
17251915
1720612
10454496
7838118
19463875
21729729
|
GNRH1
|
GNRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
26398856
414473
11726197
17452338
9414473
19640273
26774084
4930860
17095587
|
CORT
|
SSTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
15333679
9125122
9650799
10598788
|
CORT
|
SSTR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
15333679
9125122
9650799
9205124
10598788
|
CORT
|
SSTR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
11011067
9125122
9650799
9205124
10598788
|
CORT
|
GHSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12161511
1122773711227730
11227737
|
OXT
|
AVPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
9884074
9322919
12660315
9264324
7774575
9459574
|
OXT
|
OXTR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
10519430
8955347
12660315
10698266
16158071
7774575
7475979
1313946
|
RLN3
|
RXFP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16411781
|
RLN3
|
RXFP4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17606621
25761609
18582868
14522967
27888281
15367576
15525639
31780677
|
RLN3
|
RXFP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17351017
25761609
24615237
20159943
24641548
15367576
27245781
18434306
14522968
22257012
|
GHRL
|
GHSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
29233536
12907757
21402696
11314756
11227737
10628755
10604470
15905359
15070777
|
NPY
|
PRLHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15885496
|
PTH
|
PTH2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
7797535
9482662
11861531
|
TAC3
|
TACR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9190866
8925404
12727971
|
TAC3
|
TACR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
7682062
9190866
8925404
7961636
10189055
|
KISS1
|
KISS1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
15665093
11457843
11385580
12944565
|
SST
|
SSTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
9724791
15333679
9784130
8702767
9650799
1346068
8769372
11520208
9652348
7988476
10598788
|
SST
|
SSTR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
9724791
15333679
9784130
1337145
9600011
8097479
9650799
8769372
11520208
7988476
10598788
|
SST
|
SSTR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
10433861
9724791
15333679
9784130
9600011
9650799
8769372
11520208
8100352
7988476
10598788
|
GHRH
|
GHRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
1333056
26917260
7680413
76804131333056
|
PRLH
|
PRLHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
10475064
9607765
11030716
12606605
|
LHB
|
LHCGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
3470775
10446903
12727981
1922095
|
APLN
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10617103
12939143
11336787
10802050
10777510
12603839
16189514
9792798
15341513
|
APELA
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
29357134
25995451
25639753
29079036
28137936
26611206
28663440
24316148
|
SPX
|
GALR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
30305242
24517231
|
PMCH
|
MCHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
11478907
10421368
10421367
11375253
11839762
|
RLN2
|
RXFP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
11809971
12506116
22973049
15649866
18434306
|
RLN2
|
RXFP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20159943
24641548
32103204
|
RLN1
|
RXFP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11809971
16411781
|