MAPK9
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14673001
17555943
|
MAP2K1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15994315
15121878
|
ITPR1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907555106
19706527
|
MAPK1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
PPP2CA
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
AMBRA1
|
BCL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
intact
|
8174954
21358617
|
HIF1A
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12205045
20668552
|
MAPK1
|
BCL2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
BCL2
|
MAPK8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15733859
5217553
|
BCL2
|
AMBRA1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
8174954
21358617
|
BCL2
|
PPP2CA
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217079
15225643
|
DAPK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19395874
|
KRAS
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16483930
29311131
|
HIF1A
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17558861
19211554
|
BCL2L1
|
MAPK8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
15733859
5217553
|
DDIT4
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19557001
7255791
|
DDIT4
|
TSC2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
18198340
19557001
|
DDIT4
|
TSC1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
2.0
|
0.8
|
ACSN
|
18198340
19557001
|
IRS1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
TLR2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17126326
5219377
|
EGFR
|
IRS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18776048
0806158105
|
EGFR
|
NRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
KRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
EGFR
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
1845983
|
SRC
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
RAF1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20674547
15664191
|
MAPK1
|
MAP2K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
23241949
8412360
|
MAPK1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15778365
|
SRC
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16580177
9924018
|
MAPK3
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7717053
20154642
|
RAF1
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20674547
15664191
|
MAPK3
|
IRS2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
MAPK3
|
IRS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7739560
8816480
|
MLST8
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12087098
9465032
|
MTMR14
|
MAP1LC3B
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19590496
7904087
|
MTOR
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
MTOR
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
AKT1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17611497
18954143
|
MAPK8
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033842
16982329
|
RRAS
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
PIK3R1
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
6730400
7589433
|
PIK3R1
|
IRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23617393
8427684
|
TLR2
|
PIK3R1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
23247210
8402360
|
RRAS
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17474147
|
PIK3R1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7642542
16982329
|
PDPK1
|
PRKCD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12840507
9889098
|
RRAGD
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20006481
18497260
|
SQSTM1
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
MAP1LC3A
|
SQSTM1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
TSC1
|
TANK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
UBB
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PRKCQ
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18772140
17948050
|
TRAF6
|
TAX1BP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
17703191
5226445
|
TRAF6
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19713527
|
TRAF6
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20501938
|
UVRAG
|
SH3GLB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7216089
17891140
|
STX19
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SNAP29
|
VAMP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23466629
23578367
|
SNAP29
|
STX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23466629
23578367
|
SNAP29
|
STX17
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
23466629
23578367
|
SNAP29
|
VAMP8
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
23466629
23578367
|
TP53INP2
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20010805
7714020
|
GABARAPL2
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
VTI1B
|
STX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PPP2CB
|
IGBP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
27880917
|
DAPK1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19180116
7014480
|
BECN1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BECN1
|
DAPK1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19180116
7014480
|
SH3GLB1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21311563
17891140
|
TSC2
|
DAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8057025
21134130
|
TSC2
|
TSC1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6547838
9580671
|
SNAP23
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15753124
20634814
|
SNAP23
|
STX4
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15753124
20634814
|
SMAD4
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8308197
22045334
|
SMAD4
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11740493
|
HIF1A
|
PTEN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18340011
19648120
|
PTEN
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11943559
23331499
|
PTEN
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10644997
|
RRAS2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216198
12620389
|
RAF1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19197339
7014125
|
MRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10498616
20080631
|
HRAS
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12695509
5216326
|
HRAS
|
VPS11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9069260
21779497
|
STX6
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
VAMP4
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
VAMP3
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
STX7
|
STX4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
DAPK1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20389280
7900485
|
MAPK8
|
CFLAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18471544
|
SH3GLB1
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17891140
|
NRBF2
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
28059666
24785657
|
ATG7
|
ATG5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11265251
|
ATG12
|
ATG10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23725295
24070470
|
ATG12
|
ATG10
|
â—¼ PROTEIN_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23725295
24070470
|
STX17
|
VAMP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
23466629
23578367
|
STX17
|
VAMP8
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
23466629
23578367
|
PRKACA
|
CDH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
UBC
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6504434
17936276
|
RRAS
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
TSC1
|
NRBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
TSC1
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
RB1CC1
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16043512
|
AKT2
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12150915
12172553
|
AKT3
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12150915
12172553
|
INS
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9609109
15316008
|
IRS1
|
IRS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11912194
|
IRS2
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8662806
5221055
|
PIK3R3
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0611271104
17360667
|
IGF1R
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
7541045
|
PRKACA
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RPS6KB1
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
MAPK8
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16306447
|
GABARAPL1
|
ATG7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20562859
|
PIK3CD
|
IRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11598010
12506011
|
INS
|
IRS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9609109
15316008
|
MAPK8
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17050683
18029441
|
ZRANB1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
ERN1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6542966
18369366
|
UBC
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18636086
6804508
|
UBC
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
UBC
|
ZRANB1
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
NBR1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
PRKACA
|
MAP1LC3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20713600
|
NBR1
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
NBR1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19427866
7034152
|
TP53INP2
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19056683
|
ATG4B
|
MAP1LC3B
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
7261317
19322194
|
STX5
|
BET1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15215310
12388752
|
YKT6
|
GOSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24119662
19164740
|
GOSR1
|
BET1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15215310
12388752
|
PIK3CD
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PIK3CA
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
RRAGC
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PIK3CD
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9885561
10455108
|
PTPN12
|
STX16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
ULK1
|
DAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21169990
|
RAB7A
|
ATG9A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
21169990
8141833
|
ULK1
|
ATG16L1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23392225
8428476
|
GABARAPL1
|
CALCOCO2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
ATG4D
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19549685
|
SMCR8
|
C9orf72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
MLST8
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
MLST8
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
STX7
|
YKT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
GABARAP
|
STX17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
MAPK8
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
IGF1R
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
ATG4A
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
PTPN12
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
28065597
|
PIK3R1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
16273093
5218056
|
IRS1
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16354680
19561084
30240640
|
UBC
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5216530
12857745
|
VAMP2
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
12130530
|
GOSR1
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
11927603
|
C9orf72
|
SMCR8
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.81
|
0.81
|
mint
|
27103069
|
C9orf72
|
SMCR8
|
â—¼ GTPASE_REACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
27103069
|
ATG7
|
GABARAPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
811.0
|
0.81
|
STRING
|
36370105
|
CDH1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
ULK2
|
ATG13
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20562859
18936157
|
IRS4
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24797263
16273093
|
EGFR
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17047074
17307140
|
MSH2
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
27173435
31980649
|
VAMP7
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
19557002
|
VAMP3
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
19557002
|
STX11
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
STX8
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
33961781
|
AKT2
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHEB
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
STX4
|
USE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
32296183
|
RHEB
|
LAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
32814053
|
VPS41
|
STX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33422265
24554770
|
STX17
|
VPS39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33422265
24554770
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
STX6
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
33961781
|
BET1
|
VAMP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
29568061
|
BET1
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
29568061
|
VAMP4
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BET1L
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11927603
12388752
|
VAMP4
|
GOSR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GOSR1
|
BET1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11927603
12388752
|
STX18
|
BET1L
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VAMP7
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
19557002
|
STX11
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
STX6
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
33961781
|
STX11
|
VAMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VAMP4
|
USE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
SMCR8
|
ULK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30669939
27103069
|
STX2
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12828989
29360461
|
STX11
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
STX11
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
STX11
|
VTI1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
BAD
|
BCL2
|
â—¼ RELOCALIZATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
15694340
|
MAP1LC3B
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
UBB
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
KRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
GABARAP
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
824.0
|
0.82
|
STRING
|
36370105
|
STX6
|
VAMP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
TSC2
|
MTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
12271141
|
STX16
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
ATG16L1
|
WIPI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
BECN1
|
HMGB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
29361549
23954414
20819940
|
TRAF6
|
UBC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14743216
17703191
19820695
18239685
|
UVRAG
|
VPS18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20562859
18552835
|
STX19
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX19
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX19
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX19
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX6
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX3
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
VAMP4
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
19557002
|
STX18
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX4
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
25416956
33961781
|
STX4
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
8153045
21516116
|
STX4
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
34079125
32296183
25416956
|
TSC1
|
RHEB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12820960
30514904
|
WIPI2
|
ATG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
30340022
33961781
24954904
26186194
|
AURKA
|
MTMR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
27432908
33961781
26186194
|
AURKA
|
MTMR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
28675297
|
STX2
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
12828989
29360461
|
STX6
|
STX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX3
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX3
|
VAMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX3
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX18
|
BET1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX18
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
USE1
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX7
|
GOSR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BET1L
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11927603
12388752
|
STX7
|
USE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX7
|
STX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX18
|
VAMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NRBF2
|
ULK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20562859
28059666
|
VTI1B
|
STX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX18
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
STX11
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
25748427
|
STX2
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
32296183
12828989
24373201
|
ATG4B
|
GABARAPL2
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
16303767
|
SNAP23
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
RAB7A
|
VPS18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
RHEB
|
TSC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
ATG13
|
C9orf72
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
RPTOR
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
SQSTM1
|
WDFY3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
BECN1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ATG14
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
IGF1R
|
INS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
STX3
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
BET1
|
GOSR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ATG16L1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
C9orf72
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
AKT1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
MTOR
|
RPS6KB2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
11733037
|
ULK1
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25686248
21795849
21460634
21460630
|
AKT1
|
STK11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
OPTN
|
WIPI2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31723608
29133525
|
AKT1
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10497255
17640984
|
AKT1
|
AURKA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
STX3
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
26553929
10336434
33961781
29360461
26186194
|
MAP1LC3A
|
NBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
BET1
|
VTI1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
29568061
|
BET1
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
29568061
|
GOSR1
|
YKT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
VTI1A
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11101518
|
VTI1B
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
33961781
27791468
26186194
|
SEC22B
|
STX18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
MTOR
|
ULK1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
21460634
|
UBB
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
GABARAP
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
GOSR2
|
SEC22B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
ATG3
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
NBR1
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
GOSR1
|
SEC22B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
STX7
|
VAMP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
MAPK1
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
STX7
|
STX8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
ATG4B
|
GABARAP
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
16303767
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
RHEB
|
MTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18550814
16098514
16915281
15854902
33157014
15772076
15878852
25351248
|
RPTOR
|
RRAGA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
18497260
31601708
23184942
21816923
26582740
33961781
26186194
31601764
33157014
25561175
24337580
|
STX8
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
30833792
33961781
|
RAF1
|
RRAS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
STX4
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
25416956
30833792
33961781
|
PIK3CA
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
34591642
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
VAMP8
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12130530
10336434
|
STX1A
|
VAMP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12093152
32296183
9144278
|
STX5
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
30833792
33961781
|
STX16
|
VAMP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
32296183
25416956
30833792
33961781
|
RAB7A
|
VPS18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28325809
25445562
|
RAB7A
|
VPS39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25445562
33947832
|
BET1L
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
AKT1
|
PTEN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
SMCR8
|
WDR41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
RPS27A
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
BET1
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
GOSR1
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
IGF1R
|
IRS1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
17827393
|
RPTOR
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
EIF2S1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
RPTOR
|
RRAGC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25567906
21981924
18497260
31601708
21816923
25446900
31601764
25561175
24337580
|
TRAF6
|
ULK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33201521
23524951
|
TRAF6
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10635328
16189514
22447928
29545793
|
AKT1
|
PTEN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12297295
19903340
12077256
28628118
20605778
28205554
10866658
20596030
|
RAF1
|
RRAS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10848612
19805522
|
ITPR1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24947355
18250332
|
ULK1
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
8428476
23392225
|
ATG13
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
ATG101
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
IGF1R
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ATG13
|
GABARAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
STX1A
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
CALCOCO2
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
863.0
|
0.86
|
STRING
|
36370105
|
BCL2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
MAP1LC3B
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
STX4
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
867.0
|
0.86
|
STRING
|
36370105
|
BCL2
|
ITPR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19706527
15613488
|
EGFR
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
ULK1
|
MTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25686248
23524951
29321306
21460630
|
BECN1
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
23974797
|
STX4
|
VAMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
16189514
25416956
33961781
|
VAMP8
|
STX17
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33422265
23217709
31251111
25419848
|
STX3
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
29360461
33961781
26186194
12828989
|
ATG10
|
ATG7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
12482611
20562859
33961781
26186194
|
STX7
|
STX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
STX3
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
30886144
33961781
26186194
|
STX6
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
STX7
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
GOSR2
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
25416956
33961781
26186194
|
VAMP3
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26186194
34079125
19557002
|
VAMP4
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26186194
34079125
19557002
|
VTI1A
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11101518
28514442
26186194
33961781
|
STX7
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33422265
33961781
26186194
34079125
|
STX6
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
26186194
11839770
19557002
|
STX6
|
STX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
26186194
|
VAMP4
|
VTI1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
11839770
33961781
|
STX11
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
21988832
|
MTMR3
|
MTMR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25659891
27880917
26787466
28675297
27432908
|
BCL2
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GABARAPL1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
BECN1
|
NRBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ATG14
|
NRBF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MAP1LC3A
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
NRBF2
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
NRBF2
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALCOCO2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
STX7
|
VTI1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
SNAP29
|
STX7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
OPTN
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
STX16
|
VAMP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
NRAS
|
RAF1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
21779497
|
PIK3R2
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
TAX1BP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
STX6
|
STX7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BAD
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PIK3R1
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
RAF1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
VAMP4
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
BNIP3
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10381623
7954800
23504944
10625696
|
RRAGD
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
26582740
24337580
18497260
22424946
|
VTI1A
|
STX8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11101518
33961781
|
OPTN
|
UBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31723608
22101367
23414517
|
BECN1
|
TSC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20562859
28628118
28205554
|
BECN1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29669822
23112296
28628118
28205554
|
BECN1
|
NRBF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
24785657
24849286
20562859
26496610
33961781
26186194
25086043
28059666
|
CFLAR
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
16537561
10837247
21988832
|
VAMP7
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
14993220
12853575
|
ATG5
|
ATG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
24186333
20562859
33024031
33961781
|
TSC1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28628118
15342917
12167664
28205554
|
IGF1R
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7559507
8776723
10082579
7541045
8530377
33991522
8895367
12220227
15629149
8662806
|
STX3
|
VAMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
26553929
33961781
26186194
9614185
12828989
9701566
|
RAB1A
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
34079125
26344197
|
GOSR1
|
BET1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11927603
29568061
33961781
|
STX7
|
BET1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
29568061
26344197
|
BET1
|
GOSR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
33961781
29568061
|
VPS18
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11382755
16189514
|
STX7
|
VAMP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
12175335
33961781
26186194
11278762
34079125
19557002
|
VTI1B
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
27791468
33961781
26186194
34079125
|
USE1
|
STX18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
26186194
19369418
|
ATG4B
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
STX3
|
VAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
ATG4B
|
GABARAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
BECN1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
INS
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
1851182
|
BNIP1
|
STX18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CDH1
|
CTNNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MAPK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
SNAP29
|
VAMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
ATG7
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
ATG3
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
CALCOCO2
|
MAP1LC3C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
ATG13
|
ATG101
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8428476
23392225
|
ULK1
|
ATG13
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
27617292
32543267
32668203
23524951
25686248
33450483
20562859
25126726
29196462
18936157
19597335
21460634
23392225
26018823
33499712
32707033
27203176
33422265
30853401
21460630
|
TLR2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17126326
24658140
25402006
31980649
|
EGFR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
MLH3
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24443562
32814343
11292842
33961781
27229929
10615123
|
RPTOR
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
STX8
|
VTI1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
16189514
11101518
10683148
33961781
26186194
21516116
|
STX8
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
11101518
12175335
33961781
26186194
34079125
|
AKT1
|
TSC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12438239
12150915
15342917
12167664
|
RRAS2
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
10783161
10557073
11788587
12620389
10064593
|
STX7
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
21516116
34079125
|
STX6
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
25416956
33961781
26186194
21516116
34079125
|
STX11
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16189514
33961781
10036234
|
STX7
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
34079125
26344197
|
RAB1A
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26824392
|
BET1
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11927603
29568061
9094723
33961781
|
GOSR2
|
STX6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
STX6
|
STX7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16189514
33961781
26186194
11278762
34079125
|
VAMP3
|
STX6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
27791468
33961781
26186194
34079125
11839770
19557002
|
RRAGA
|
RRAGD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16189514
26582740
33961781
26186194
28716898
11073942
25561175
22424946
|
VAMP4
|
STX16
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
11839770
|
VPS41
|
VPS11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33422265
26463206
33961781
26186194
28931724
|
VPS11
|
VPS39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
32296183
33422265
26463206
33961781
26186194
23901104
22939629
|
PIK3R1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
IRS1
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
AMBRA1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
EGFR
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
ATG16L1
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
SNAP29
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
STX8
|
VAMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
HIF1A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
GABARAPL2
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ATG16L1
|
ATG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
RAB1A
|
RAB8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
MAPK3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19777442
10597268
12566304
|
MAPK1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
8929531
10597268
12566304
|
RAF1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8929532
8910675
12488548
9194558
15849194
|
BECN1
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22498477
21971985
20889974
20010695
23504944
23564079
23168911
25891078
29955058
23822101
32097085
23954414
19959994
28128446
22241963
16179260
23316280
31410188
18641390
29079782
29849149
28682313
27304906
20711182
25984893
22622204
19180116
20622903
33977871
23541952
24034250
22082873
21543763
19347031
31696776
9765397
16713569
24879154
24141421
17446862
24472739
24599950
28431397
20577262
19050071
32820146
21358617
21139567
23479509
|
BCL2L1
|
ZFYVE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PDPK1
|
DDIT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
SRC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
17284441
6169640
|
EGFR
|
PTPN12
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
21376233
7542744
7541030
|
HMGB1
|
TLR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23519706
20192808
16267105
|
HMGB1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20819940
|
MAPK1
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK1
|
MAP2K2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
PPP2CA
|
MAPK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
211739200
12840032
8214413
|
MAPK1
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15851026
17671177
|
MAPK1
|
GORASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
20083603
15834132
|
MAPK3
|
MAP2K2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
MAPK3
|
MAP2K1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
10567369
19219045
8013650
|
PPP2CA
|
MAPK3
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
211739200
12840032
8214413
|
MAPK3
|
STK11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
25846811
|
MTOR
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16847060
26522726
12604610
19619545
26348909
33378666
20169205
24036451
18570873
24516643
19299511
34031390
22424946
22356909
25940091
12719976
22544753
23263282
12150926
12665511
18505677
17277771
17461779
22493283
19114562
18722121
21071439
18030348
19446321
12718876
12747827
24375676
22258093
16837165
21045808
16962653
18955708
17565979
12408816
15467718
23953116
27043084
23911927
17043309
31601708
21177249
21614075
21795849
16631613
20381137
21321085
23297343
23872070
16354680
19875983
25446900
29059166
24337580
16603397
16183647
34171383
15066126
24403073
25332233
17386266
19145465
25007995
16798736
26678875
15268862
20427287
30865892
16919458
25273559
15459249
18519641
18504440
12150925
|
MTOR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
18566587
25792870
15718470
14970221
24670654
10910062
18505677
29567957
22337773
21177249
26293922
19299511
18566586
30639242
21045808
11438723
22084251
23872070
21343617
22307628
|
PRKAA1
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14970221
|
MTOR
|
NRBF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28059666
|
IRS4
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18165436
11912194
|
PPP2CB
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11959144
|
PRKCD
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17183360
16483929
|
PRKCD
|
CDH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
27203386
|
RHEB
|
RPTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16631613
25446900
15854902
33157014
24337580
|
AKT2
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17517883
18372248
17277771
|
TRAF6
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
34938598
19713527
|
BECN1
|
UVRAG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29313410
19270696
21597469
25275521
32097085
22314358
24956373
23954414
25533187
34386498
32296183
20562859
22081109
18641390
26496610
27621469
31373534
23878393
19270693
24056303
27203177
33977871
24034250
19372752
30686098
30258449
22493499
24879154
25490155
19050071
29866835
18843052
|
UVRAG
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18843052
24785657
|
PRKACA
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19942859
|
TP53INP2
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20010805
19056683
|
TBK1
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
18307994
6492190
|
OPTN
|
TBK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27086836
25923723
32556086
29395067
27035970
27538435
25803835
26365381
20174559
27620379
30327196
23414517
18307994
31723608
32707033
21903422
|
RHEB
|
TSC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12869586
12820960
30514904
12842888
17077083
15854902
12771962
|
AKT3
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12150915
12167664
12172553
|
STX11
|
SNAP23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AKT1
|
SMAD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16362038
23397142
|
SMAD4
|
CDH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22775504
17452626
24625091
|
PDPK1
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17496917
15125833
16056267
|
PPP2CA
|
MAP3K7
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
608155200
17079228
8204431
|
RAF1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
502464200
8203796
16239230
|
AKT1
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
25241761
28628118
10576742
19197339
19058874
28205554
|
RHEB
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16803888
19222999
9001246
15150271
15854902
|
SRC
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17097642
16189514
7517401
8876196
10205168
|
RAF1
|
PPP2CA
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
502464200
8203796
16239230
|
VAMP3
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
16189514
25416956
10820264
34079125
12130530
12828989
|
CFLAR
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19838173
|
ATG3
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
32296183
11825910
20723759
24186333
23202584
17353931
20562859
33961781
30778222
34079125
|
WDFY3
|
ATG12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20417604
|
SRC
|
PPP2CA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15637081
15004239
15564375
|
SRC
|
PPP2CB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
15637081
15004239
15564375
|
SRC
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
22402981
|
SRC
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
30644389
26854235
9096340
|
PDPK1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
9368760
11825911
14500673
10698680
31467278
12149249
27563096
11313365
11278835
22569334
26264872
10226025
32876514
26256536
21775285
11438723
11445557
23397142
|
PDPK1
|
AKT2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9228007
9094314
15890450
|
MAP2K1
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11160134
|
MAP1LC3C
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20562859
22170151
|
IRS2
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9113989
|
PPP2CB
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
2826472
11124802
10200280
|
PRKACA
|
CAMKK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
32913128
10187789
15209507
|
ATG4B
|
MAP1LC3C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20562859
32296183
15187094
|
GOSR2
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
16189514
9094723
9647643
11927603
11035026
|
STX7
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
11101518
33422265
33961781
26186194
11278762
34079125
19557002
|
STX7
|
VTI1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
12175335
33961781
26186194
34079125
12114520
|
STX6
|
VAMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
16189514
17159904
10359608
25419848
33961781
34079125
11839770
19557002
|
STX6
|
VTI1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
17159904
33961781
26186194
34079125
|
RRAS2
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19561613
|
MAPK9
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAPK8
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
MAP2K4
|
MAPK10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16186825
9162092
17875933
|
VAMP4
|
VTI1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
11839770
33961781
17159904
|
WIPI2
|
ATG16L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28561066
34505572
29634932
|
RAB33B
|
ATG16L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18448665
|
NRBF2
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
28059666
32296183
24785657
|
ERN1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18471544
27009865
|
PRKAA1
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19217427
|
PIK3R2
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22402981
8596638
11733063
|
TBK1
|
CALCOCO2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19820708
21903422
|
RB1CC1
|
ULK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19225151
18936157
|
WDR45
|
ATG2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
28561066
20562859
|
GABARAP
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
ATG3
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
STX7
|
VAMP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
AKT1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
NBR1
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
BAD
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
906.0
|
0.9
|
STRING
|
36370105
|
EIF2AK4
|
EIF2S1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
32513922
|
MTOR
|
AKT1S1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
18372248
|
ULK1
|
RB1CC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
19597335
|
RPS6KB1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
TRAF6
|
MAP3K7
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18758450
|
TSC1
|
RHEB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
20006481
|
ULK1
|
ATG13
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
19211835
|
PIK3C3
|
UVRAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
SNAP29
|
STX1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
STX4
|
VAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
STX5
|
YKT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
STX5
|
YKT6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
11927603
33961781
|
STX7
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
STX3
|
VAMP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
BCL2L1
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
TRAF6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
SNAP23
|
STX1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
SNAP23
|
STX3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
RRAGA
|
RRAGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
SNAP23
|
STX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
IRS1
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
STX6
|
VAMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
TSC2
|
RHEB
|
â—¼ GTPASE_REACTION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
15340059
|
PIK3R1
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
6731578
14632132
|
SQSTM1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
TBK1
|
TANK
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
5220020
17568778
|
IRS2
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
ATG14
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
IRS1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
STX7
|
VAMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
ATG7
|
GABARAPL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
MTOR
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
21592956
|
RPS27A
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
MAP2K2
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
STX6
|
VTI1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
925.0
|
0.92
|
STRING
|
36370105
|
SQSTM1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
MAP2K4
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
926.0
|
0.92
|
STRING
|
36370105
|
ULK1
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
8428476
23392225
|
VPS33A
|
VPS16
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
29778605
|
NRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.93
|
0.93
|
mint
|
30194290
|
ATG7
|
ATG12
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
18704115
|
RAB1A
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
MAP1LC3B
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
MAP1LC3A
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ATG4B
|
GABARAPL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
RAB7A
|
VPS33A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS33A
|
YKT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS33A
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS33A
|
VPS39
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
STX8
|
VTI1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
AKT1
|
PDPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS18
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS18
|
VPS39
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS16
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS41
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VTI1A
|
YKT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS39
|
VPS41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
VPS16
|
VPS39
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
ATG7
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
12482611
11890701
20562859
28253953
11096062
|
VPS16
|
VPS41
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
26463206
26496610
33961781
26186194
22939629
|
GABARAP
|
WDFY3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATG12
|
ATG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
PIK3CA
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
STX6
|
VTI1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
MTOR
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
ATG7
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
STX6
|
VAMP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
NRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
MTOR
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
PIK3CB
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
ATG7
|
GABARAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
NBR1
|
RPS27A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
BECN1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
19180116
7014480
|
BCL2
|
BECN1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
8095158
21139567
|
MSH2
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
25241761
10783165
31843968
30770470
12799449
10748159
|
SQSTM1
|
MAP1LC3A
|
â—¼ COLOCALIZATION
|
✅
|
|
0.95
|
0.95
|
mint
|
19427866
7034152
|
PPP2CA
|
IGBP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8434208
23892082
|
ATG3
|
ATG7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
28514442
11825910
24186333
20562859
33961781
26043688
|
MAP1LC3B
|
ATG4B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
20010802
7715597
|
MAP1LC3B
|
ATG4B
|
â—¼ CLEAVAGE
|
✅
|
|
0.95
|
0.95
|
mint
|
19322194
7261317
|
RRAGD
|
RRAGB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
18497260
33961781
28716898
11073942
20381137
24337580
22424946
|
GOSR2
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
RB1CC1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
MLH1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
GOSR1
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAB7A
|
VPS41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAB7A
|
VPS16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAB7A
|
VPS39
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RAB7A
|
VPS11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
RHEB
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
RRAGB
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
UBA52
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
UBA52
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
RPS27A
|
UBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
RPS27A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
MAP2K2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
STX8
|
VAMP8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11101518
33961781
19557002
|
RAF1
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
7014125
19197339
|
VAMP8
|
STX4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12130530
29360461
10820264
|
ATG10
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
12482611
17353931
33961781
26186194
|
RRAGC
|
RRAGB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
25567906
21981924
33961781
28716898
11073942
20381137
25561175
24337580
22980980
22424946
|
RRAGC
|
RRAGA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
16189514
25567906
21981924
16713569
31601708
21816923
23184942
33961781
26186194
33157014
11073942
28716898
20381137
25561175
24337580
25936802
22424946
|
VPS18
|
VPS41
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
22939629
33422265
26496610
26463206
33961781
26186194
23901104
25783203
28931724
|
VPS16
|
VPS11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
26463206
26496610
33961781
11382755
23901104
|
RPS6KB1
|
MTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
15905173
|
MTOR
|
RPS6KB1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.96
|
0.96
|
Signor
|
12782654
|
ATG3
|
GABARAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
ATG13
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
ATG12
|
ATG16L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
MAP2K1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
TANK
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
C9orf72
|
WDR41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
ATG16L1
|
RAB33B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
SRC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
8845374
21573184
25402006
7506422
10075741
19704002
10971656
23175185
10777553
22227249
20935677
20624308
21268077
17158602
24189400
9020193
16713569
22973453
11983694
24658140
28065597
21278788
17284441
7797556
20333651
7527393
10358079
|
PIK3R1
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
20018188
7383613
|
TBK1
|
TANK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21931555
16189514
31114588
21988832
30420664
21903422
14743216
10581243
29395067
30561431
23286385
27035970
25409927
17823124
32707033
17568778
24488098
23007157
33961781
18307994
29251827
|
OPTN
|
RAB8A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
20161783
20388642
23357852
20634958
22854040
11137014
20085643
|
TSC1
|
TSC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16464865
25263562
11290735
17077083
12511557
11741832
10807585
11175345
20166753
15342917
30514904
11741833
17658474
15963462
16339216
20169078
10585443
14551205
9580671
12167664
10915759
16424383
20412061
12869586
16636147
9809973
14651849
28561026
15851513
17693255
21134130
15340059
12176984
15851026
|
ATG5
|
ATG12
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11825910
12890687
12482611
17353931
20562859
23202584
31612776
22342342
33961781
28253979
33024031
32129924
|
ATG4B
|
MAP1LC3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
RHEB
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
MAP2K1
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ATG3
|
ATG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
BECN1
|
UVRAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
KRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
MTOR
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
STX18
|
USE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
MAP2K1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
AKT1S1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
MAP1LC3B
|
OPTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
AKT1S1
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
SEC22B
|
STX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
C9orf72
|
SMCR8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
OPTN
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
RPTOR
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
24036451
|
MTOR
|
RPTOR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.98
|
0.98
|
mint
|
21045808
8088164
|
HRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
RAF1
|
HRAS
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
STX4
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
8760387
25416956
32296183
10820264
12417022
8770861
12517971
10194441
30217970
29360461
34079125
|
NBR1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
UBC
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
OPTN
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
TSC1
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ATG4B
|
MAP1LC3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
IGF1R
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
MAP2K2
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
VPS11
|
VPS33A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
ATG3
|
ATG7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
PIK3CD
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
VPS11
|
VPS16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
PIK3CA
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
ATG101
|
ATG13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
MTOR
|
RPTOR
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.98
|
0.98
|
Signor
|
19346248
|
BAD
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
7834748
9388232
17446862
9463381
20603619
10611223
14681455
11483855
33961781
19168699
15990872
9305851
15849194
|
STX1A
|
VAMP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12093152
32296183
9030619
19293945
7553862
10449403
10100611
11832227
23100443
20798282
|
GOSR1
|
STX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16189514
9094723
9647643
9325254
12388752
11927603
|
VPS11
|
VPS18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
26496610
33961781
26186194
11382755
25783203
23901104
28931724
|
VPS16
|
VPS18
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
22939629
26496610
26463206
11382755
25783203
23901104
|
VPS33A
|
VPS41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
VPS11
|
VPS18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
VPS16
|
VPS18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
VPS11
|
VPS41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
VPS11
|
VPS39
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
RPS6KB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
VPS18
|
VPS33A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ATG12
|
ATG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
VPS16
|
VPS41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
RPS27A
|
UBA52
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
VPS18
|
VPS41
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
MTOR
|
RHEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ATG14
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ATG16L1
|
ATG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
IRS1
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
MAP3K7
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ATG12
|
ATG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
MLST8
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
VPS16
|
VPS33A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RRAGB
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RRAGA
|
RRAGD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPTOR
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IGBP1
|
PPP2CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
IGBP1
|
PPP2CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
STX1A
|
VAMP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MLST8
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
ATG13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15755954
16469695
17680028
18000759
18492954
19022819
19151919
19225151
19446321
19568798
19706736
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
ULK1
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
15197469
19225151
21460630
18936157
27932573
19287211
19597335
27390127
27387056
27203176
25686248
26018823
20562859
23524951
33450483
26687599
19211835
23392225
26138443
25126726
|
MTOR
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
12150925
18000759
19225151
21157483
17680028
19151919
19864431
26801615
15755954
19446321
19258318
19706736
12408816
19211837
11274345
19211835
19568798
|
ULK2
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
20562859
19225151
18936157
|
ATG101
|
ATG13
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
20562859
23392225
26299944
19287211
24290141
19597335
24100292
|
ATG13
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
19211835
|
BCL2
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
BCL2
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10826997
10949026
11342610
11704864
12107820
12175651
12444011
12767520
16931767
17446862
19030972
19641503
21540285
22039431
23064052
23377657
23430059
23850759
8929532
9346240
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
RAF1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
11532940
12107820
12566895
14764585
15516985
19289794
19565474
24027568
8929532
9069260
|
PRKCQ
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10652356
15214048
15536066
16606694
17544292
17548359
18784374
19201850
23077238
23433459
23474202
23886063
25960930
|
MAPK8
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
11983683
12189144
14673001
16166315
15526032
29795446
15907327
14967141
15725726
17555943
|
PRKACB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
PRKACG
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
15280015
10611223
10230396
12954615
9346240
10949026
11493700
10230394
10558990
8929531
9381178
17270021
10837486
|
RAF1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
11983683
12444011
10880354
19030972
19667065
22096607
15849194
16931767
17535812
16103085
9381178
23162742
12107820
18402774
12767520
10826997
8929532
8929531
12175651
25241761
19565474
10949026
19165420
9069260
21540285
17242355
23397142
19289794
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
RPS6KB1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15280015
10611223
12954615
9346240
11493700
10230394
10558990
8929531
9381178
19641507
17270021
10837486
|
PRKACA
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
11983683
10880354
20166139
9346240
11493700
9381178
18794113
12931191
15280015
10230394
10558990
8929531
18669648
10837473
10837486
10611223
12954615
10949026
10851172
15123689
18707149
16403219
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
AKT2
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
15452053
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
12954615
22094462
10949026
11438654
17680028
10516287
18218901
17270021
|
BAD
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
9305851
17145710
11483855
16697956
9463381
15694340
15849194
20603619
15990872
11583631
8929531
7834748
9388232
17446862
19168699
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
BCL2
|
AMBRA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
21358617
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
UVRAG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
AMBRA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11704864
17446862
21358617
22039431
23064052
23377657
23430059
23850759
8929532
|
BCL2
|
UVRAG
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
BECN1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
10604474
11704864
16179260
17106237
17446862
17891140
18612260
22039431
22885520
23064052
23377657
23430059
23850759
27754749
8929532
9765397
|
BCL2
|
RAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
11463391
11463392
11532940
11704864
12566895
12667443
14764585
15516985
17446862
19289794
19565474
22039431
23064052
23377657
23430059
23850759
24027568
8929532
9069260
9872359
|
PPP2CA
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15225643
9852076
|
MAPK3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9115213
10669763
9735392
11323415
21785723
9738012
10677502
23272207
25826088
|
BCL2L1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18835031
14980220
26186194
11583631
|
AKT1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCAP31
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9334338
17145710
|
MAPK1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
9115213
10567572
12039864
10669763
15225643
11323415
21785723
9738012
11337027
10677502
23272207
|
PPP2CB
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15225643
9852076
|
MAPK8
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
45.0
|
1.0
|
Omnipath
|
12421819
26609913
17097560
16738310
21726807
10567572
21993018
29950132
20919655
22848813
15225643
19029119
9738012
18570871
9115213
12039864
11323415
15733859
18471544
15703383
23329792
10677502
|
BNIP3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
17145710
23504944
10625696
10381623
19136941
7954800
|
AKT3
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
21303971
11882383
17680028
20214616
22094462
20398329
21506126
20028971
12040186
18218901
|
BCL2
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
72.0
|
1.0
|
Omnipath
|
23504944
17643073
23168911
21971985
19273585
16713569
19050071
16179260
23316280
22205736
23115300
18641390
28128446
17446862
23954414
22241963
23541952
29955058
25891078
29849149
24034250
24599950
9765397
25984893
21358617
18570871
16799551
19180116
20889974
20622903
23564079
19959994
20711182
23479509
19347031
20010695
21543763
22622204
24472739
17438366
|
MAPK8
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
10617621
25241761
15733859
12633850
18471544
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
BCAP31
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9334338
17145710
12594175
|
BNIP3
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
10625696
|
BCL2L1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
33931087
19180116
19049976
22219388
18628207
18641390
17659302
9765397
16713569
19713971
24443581
17446862
17337444
|
HIF1A
|
DDIT4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
DDIT4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19828020
17307335
20176937
|
PPP2CA
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18039929
16680151
10995457
18042541
18588945
|
SRC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
232.0
|
1.0
|
Omnipath
|
16414009
17081983
25958313
16943190
15618223
19935697
19305428
25402006
24797263
29285309
7488034
15592458
17389395
16461772
20562096
19275932
17897439
15899872
17570479
2803273
23636329
23246962
25505586
23175185
15615697
23349873
16849545
25356505
11983694
24189400
11756413
25748412
26325669
26150526
14512423
18789131
14750954
31978707
25573954
27495374
20071362
18707149
28759036
16729043
26494466
27716204
25537504
17237269
18687633
25884760
29036202
26936397
17575160
20926745
20935677
15282306
23702846
15476828
9069259
19336574
20421302
15660394
23866081
19377510
9777370
22426783
29321659
33706413
25841779
19840943
18669648
12397069
16843263
18957516
34088769
25077442
14963038
19836242
17653080
19625610
16936701
11960379
15548697
18295415
17523611
21268077
20333651
21399647
23376850
11250711
23942551
19704002
22927910
11160627
31952541
10777553
17016520
2543678
19258037
33883672
17646646
28102297
23873690
26771606
21573184
23119029
19151764
16713569
7797556
25955608
15302935
20407013
28513565
23119185
9990038
21080693
20190765
25347738
14630916
15708852
21822308
20628053
25301722
24658140
19690143
27564112
20802523
29124875
33657368
12101233
21787862
14764607
17284441
12878163
26290602
15951569
16543144
15212693
17971399
14523024
10971656
21278788
8845374
22430206
18083107
29641465
18234969
18460189
17551925
22957061
26571308
17043637
20371672
10358079
16799092
19154417
23066441
28065597
12842895
18180459
17158602
18271526
15657067
25159151
34367939
24919575
10075741
25366117
24349301
17561374
16862179
20215522
31980649
24335899
16037379
18451158
14530278
16505275
12063263
23449029
11311660
|
CDH1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17548604
10969083
15662113
31980649
14681060
25241761
24189400
25468996
24658140
25402006
|
MAPK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
12556561
1651322
17081983
3138233
15901825
1939237
91332050
2543683
2115882
17192257
1651323
15302935
|
MAPK3
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
1651322
17081983
3138233
15901825
16785992
1939237
91332050
27531070
17570479
2543683
2115882
34086370
17192257
1651323
15302935
|
PTPN2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15592458
15588985
9488479
10488121
11514572
11479308
|
PRKCD
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
11447289
8321321
11313945
12040186
15302935
6321473
1860884
6090944
19568798
14585353
17496910
21386996
2984676
11940581
85012702
19615955
2987962
12845332
3379075
15567848
16488589
17956904
|
PTEN
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16288286
10648629
17218262
12040186
15584861
|
EGFR
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
17496910
31980649
23956138
19531499
16273093
24658140
11172806
1334406
25402006
|
EGFR
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17496910
31980649
25241761
16273093
24658140
25402006
|
EGFR
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12556561
15531749
|
EGFR
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17496910
26918608
7797556
25241761
19531499
16273093
8662998
14967450
16713569
21701776
|
EIF2S1
|
EIF2AK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
18664456
12370288
16288713
17956313
11907036
10026192
|
EIF2AK3
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
76.0
|
1.0
|
Omnipath
|
25429617
25579745
14967143
17998059
21981022
27009865
10504407
23356742
3352609
26622781
24316205
24706853
16288713
20408811
30070006
18840095
27638465
21844328
21029306
23293645
21901118
29199180
30081573
14638860
19007793
9819435
23935851
8099443
21029301
19220912
31226023
25660019
22509299
22169477
11337501
24904562
15314157
9930704
23314846
17998206
17325203
16179258
25393282
19583950
26028033
29396442
26487695
10542257
18694499
1677563
11555640
24705207
20040105
24159375
25541374
24958502
11907036
29163417
|
EIF2AK4
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
22593757
28781602
15684420
10504407
3352609
24706853
20454906
9819435
8099443
15550948
27613409
11337501
32513922
9930704
29281830
21919885
17940089
22355110
16179258
30196486
19583950
28671615
10542257
1677563
25079372
15355306
|
MAPK1
|
GORASP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
19651622
17081983
18767875
20068231
17287340
16713569
19413330
11408587
|
HMGB1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
18070982
15247281
21220427
12140561
12138165
8837778
19592497
18347055
|
HMGB1
|
TLR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
10952726
11672593
12646658
12803886
15802534
16267105
16327802
19931333
21372296
22842346
26618107
27048821
27192565
|
NRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RAF1
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
HRAS
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
MAPK1
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11802164
15239952
21779496
11802165
15260967
|
MAP2K2
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
68.0
|
1.0
|
Omnipath
|
21675959
11704645
9694850
17081983
7565670
12750173
19690332
12932319
11823456
18799465
15592455
11337027
18083107
21365009
12788955
11134045
19219045
17389395
9447970
15342917
23331499
19534553
17569879
7559390
23047924
8226933
8223433
17272394
15851026
15811950
19494114
18988627
18669648
11549292
23519423
19541618
18691976
1381507
16293107
17906627
11986622
19933846
8376945
19053285
16094384
11971971
17192257
11136732
11948414
8388392
7898932
9731057
11730323
18039929
11118451
19369195
12920017
15951569
15466214
10746662
|
PPP2CA
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
12624094
12840032
18039929
16680151
16456541
10995457
18042541
10592173
7780739
18588945
2154696
20626350
|
PPP2CB
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
18039929
16680151
16456541
10995457
18042541
7780739
18588945
2154696
|
MAP2K1
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
149.0
|
1.0
|
Omnipath
|
21675959
9694850
17081983
10757792
11319218
18799465
15592455
12788955
19415658
12697810
17389395
9447970
15342917
8226933
15851026
12270934
12644307
17255949
10998418
11242034
1378617
1381507
17906627
11986622
8376945
8157000
7992057
11948414
9731057
19651622
11251083
11266467
18707149
14743221
11279118
11704645
12750173
12932319
16497976
11337027
23331499
12048245
7559390
17272394
15811950
19494114
18669648
18691976
11741894
15972258
19053285
16094384
17192257
7898932
24623782
9166761
19369195
21336309
12920017
15466214
17016520
19901323
1712480
19690332
11823456
9032297
11134045
12876277
19534553
10995751
20068231
21506533
8223433
8248196
16153436
12594221
10567369
19933846
17563371
11730323
29175850
11352917
16135787
15951569
19058874
15212693
23241949
9560161
91184134
18083107
16887817
18578522
17569879
21071413
9148935
18452278
1330321
8670897
19541618
10777511
15935618
12925710
11971971
9765155
11136732
11118451
12082107
12952943
10746662
21768338
|
MAPK1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12975377
23602568
16424009
19058874
23397142
21707490
|
MAPK1
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
15616583
|
MAPK1
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12801888
|
MAPK1
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
17081983
18767875
15849194
19690332
11409918
14654779
23331499
23180781
8226933
20068231
18988627
21917714
18669648
19541618
18691976
16407412
19933846
9922370
15664191
8388392
19651622
10801873
8349614
18775330
9604935
|
MAPK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
12054624
15547943
20080742
14967450
12040186
15173823
12697810
11940578
7545671
16227978
21035469
12738796
16039586
9722592
17255949
15774499
15187187
19541618
19091303
19565474
17052211
19085255
11279232
9271440
18039929
18775330
11705993
10601235
12792650
11431469
|
MAPK1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
21071439
19339977
19864431
21325048
22493283
|
MAPK1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16954218
10551817
18519666
18687685
26784107
|
MAPK1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15342917
15851026
18794886
|
MAPK1
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
15001544
17081983
18949383
16123357
27014871
16914728
17360977
16099428
30401435
16131083
17640984
12510059
15613682
21850561
14579029
20594869
8626671
9395471
19651622
15576463
22289259
14769130
16020478
17242212
|
MAPK1
|
STK11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
25679014
25846811
|
KRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
NRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
HRAS
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RAF1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
MAPK3
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11802164
15239952
21779496
11802165
15260967
|
MAP2K2
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
101.0
|
1.0
|
Omnipath
|
19901323
17081983
11704645
9694850
12750173
1411546
19690332
12932319
18799465
16497976
18083107
11134045
8626767
9006895
17389395
19219045
15342917
9447970
16887817
23331499
17569879
7867743
7559390
21071413
19534553
8226933
20068231
8223433
17272394
93330262
15851026
15811950
26987942
18988627
19494114
18669648
19541618
11242034
15466476
18691976
1381507
17906627
11986622
19933846
8376945
11971971
17192257
11136732
11948414
7898932
7687743
9731057
19651622
11730323
16464493
18983981
11251083
11118451
15580310
19369195
18707149
12920017
15951569
15466214
10746662
15212693
|
MAP2K1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
106.0
|
1.0
|
Omnipath
|
9694850
17081983
11319218
18799465
17389395
9447970
15342917
8226933
15851026
12270934
12644307
11242034
1381507
17906627
9677429
11986622
8376945
7992057
11948414
7687743
9731057
19197339
11704645
7565670
12750173
12932319
8626767
23331499
12048245
7559390
17272394
15811950
26987942
19494114
18669648
18691976
17192257
8388392
7898932
16464493
19369195
12920017
15466214
19690332
11134045
19534553
10995751
7867743
8223433
8248196
10567369
19933846
17563371
1518847
11730323
18983981
16186792
16135787
15951569
19058874
15212693
10748187
9560161
9925641
9733512
18083107
11104681
9006895
17569879
21071413
7731720
1330321
93330262
19541618
15466476
12925710
11971971
11136732
11118451
10746662
|
PPP2CA
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12624094
12840032
18039929
16680151
16456541
10995457
18042541
18588945
|
MAPK3
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21757713
21071439
19339977
19864431
|
MAPK3
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
15547943
20080742
14967450
12040186
15173823
12697810
11940578
16227978
12738796
16039586
9722592
17255949
15774499
15187187
19541618
19091303
19565474
17052211
11279232
9271440
18039929
18775330
10601235
12792650
11431469
|
MAPK3
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10551817
18519666
24099156
|
MAPK3
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
15001544
16131083
8626671
14769130
9335553
15613682
12510059
15212693
9395471
14579029
|
MAPK3
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
25241761
15616583
26769850
|
MAPK3
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
28115363
12801888
|
MAPK3
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15342917
16244323
15851026
18794886
19188143
|
MAPK3
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
14654779
23331499
19541618
18691976
16407412
19933846
9446616
9922370
15664191
18988627
|
MLH1
|
MLH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
15703371
16612326
16697054
18157157
18406444
19847258
20478261
|
MLH1
|
MLH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
15703371
16612326
16697054
18157157
18406444
19847258
20478261
|
MTOR
|
MLST8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
MLST8
|
â—¼ SHARES_COMPLEX
|
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
MLST8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
AKT1
|
MLST8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
SQSTM1
|
MLST8
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
25002027
26587781
28574505
|
MLST8
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MLST8
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
MLST8
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MLST8
|
DEPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
MLST8
|
â—¼ LOCALISATION
|
✅
|
|
88.0
|
1.0
|
ACSN
|
10702316
10722653
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16556040
16678438
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17461779
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18481918
18492954
18566586
18570873
18925875
19022819
19027299
19143635
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20027184
20138985
20338997
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21533173
21621563
21708191
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
9069260
|
MLST8
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RHEB
|
MLST8
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RHEB
|
MLST8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17604271
15854902
19299511
16636147
12718876
15878852
17470430
19143635
12906785
18466115
|
MLST8
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
16697215
20398329
17461779
18372248
20338997
15808505
20138985
20214616
21474067
19203586
15718470
19568798
15169778
19720745
17517883
18925875
10949026
11715018
19143635
17277771
18636226
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
MTOR
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
RPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
RPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
SQSTM1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
25002027
26587781
28574505
|
MTOR
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
MTOR
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
MTOR
|
DEPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
37.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17461779
17604271
17680028
18000759
18372248
18492954
19022819
19143635
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
MTOR
|
RPTOR
|
â—¼ LOCALISATION
|
✅
|
|
72.0
|
1.0
|
ACSN
|
10702316
11108711
11274345
11756498
12150925
12408816
12533512
12709531
12713446
12844354
12867079
12906785
15314020
15749884
15755954
15905173
16286006
16469695
16679021
16713974
16915281
17052453
17053147
17368478
17404308
17604271
17680028
18000759
18046414
18048642
18372248
18391071
18423201
18492954
19022819
19143636
19151919
19225151
19244117
19339977
19446321
19568798
19597330
19706736
19720745
19864431
19930715
20138985
20547845
20647036
20805416
20832730
20932932
21157483
21177869
21233202
21474067
21981924
22504639
23087689
24795729
24973821
25002027
25682865
25730849
26159692
26597054
27328425
27331412
27510662
27572739
28216025
|
RHEB
|
MTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RPTOR
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
139.0
|
1.0
|
Omnipath
|
15268862
24403073
20427287
22258093
21321085
19446321
15467718
19875983
17461779
12665511
12719976
16631613
21045808
21177249
23911927
24337580
25446900
24516643
18614546
12718876
12747827
16603397
17043309
18519641
22544753
25007995
27043084
19145465
23953116
19619545
16919458
24375676
15459249
16837165
16847060
25332233
12150926
22424946
26348909
12150925
18955708
20381137
22356909
17386266
17565979
18030348
16354680
20169205
19114562
21071439
27329724
35561222
16798736
15809305
22493283
17277771
15661536
16962653
1683716516603397
17604271
18676370
16183647
18505677
23297343
23872070
24036451
15066126
18570873
21614075
18722121
12408816
17599906
|
RHEB
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
18670866
18075516
18550814
16631613
18466115
16915281
23331499
15772076
16098514
20006481
15878852
21071413
23272152
19299511
15854902
19487463
20226003
19143635
17604271
16636147
17470430
12906785
|
MTOR
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
111.0
|
1.0
|
Omnipath
|
25062042
17510057
17081983
15208671
22873724
16922504
23077579
12087098
28270148
16286006
15896331
25356520
17664694
21790669
26919095
26313911
21561857
10567431
16099428
21977024
14679009
11940578
15899889
15388791
12829246
21980324
22751450
12604610
9465032
20068231
10601311
28122439
19302577
21602892
15718470
15631631
23273915
18669648
21307646
10579915
23261705
20169205
25936802
25486097
24411482
12586835
23342114
15809305
14560963
22472346
11279232
15760907
9271440
27856330
12370290
23486913
12782654
11914378
24795562
19877273
28242756
11500364
26698305
14993219
20459645
23029019
16964243
15212693
25505994
|
MTOR
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20338882
17517883
18372248
19203586
27418134
17277771
15718470
26491696
|
MTOR
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
22570710
15952059
19561084
21282364
25973388
14769130
11287630
9335553
17698034
20863384
|
MTOR
|
DEPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22017877
22017876
22017875
19446321
28086984
|
MTOR
|
RPS6KB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12150925
11914378
17510057
21157483
17680028
19864431
12087098
15755954
16286006
9465032
15060135
11733037
14560963
12408816
20932932
23486913
19568798
|
MTOR
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17517883
18372248
19203586
17277771
15718470
|
MTOR
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
70.0
|
1.0
|
Omnipath
|
18000759
19225151
21157483
25759175
15755954
28464882
19446321
27681874
26417067
28518135
19706736
24119841
27325266
26906453
27731364
29686608
25026281
27935582
28366635
28674405
27617292
26869683
29507183
25679763
28389629
25686248
19568798
27387347
21383122
26118643
32134989
26887051
12150925
29540819
29849901
10995454
23136410
30093610
19864431
24358342
26844203
29787772
30127742
19690328
21460634
26447757
26589724
21258367
22770472
29057166
29752434
29066806
17680028
19151919
24998849
30174616
26734992
17595159
12408816
11274345
|
MTOR
|
ULK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
12150925
19211836
18000759
19225151
21157483
17680028
19151919
19864431
15755954
19446321
19706736
12408816
11274345
19568798
|
MTOR
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
25.0
|
1.0
|
Omnipath
|
17604271
17386266
18030348
28978182
19114562
17517883
26876939
18570873
18372248
17277771
|
MTOR
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
24670654
16697215
11438723
21592956
20398329
17461779
18372248
21177249
21045808
20338997
15808505
16221682
20138985
20489726
15899889
20214616
8978681
21474067
14970221
19203586
17660512
15718470
19568798
20333297
23006971
15169778
25241761
18566586
19720745
17517883
18925875
22084251
10949026
14761976
11715018
19143635
17277771
18636226
10910062
15047712
9812896
18505677
21343617
19844585
17680028
19151919
18566587
9736715
23872070
10722653
20832730
18570873
17013611
17052453
12408816
15364915
11274345
|
NRAS
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3CA
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
KRAS
|
PIK3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HIF1A
|
PIK3R1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21835053
20724477
14726529
11359907
16682453
15833446
16982770
16618748
|
HRAS
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9069260
25241761
10212255
11313862
9150145
16713569
15021914
|
IRS2
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
21241768
23439647
11024460
19561084
12107746
9334184
15715521
11438664
15514089
26496610
9233603
23617393
8910607
9852124
19109239
|
IGF1R
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8603569
17496910
25241761
8697095
7642582
17570479
18595745
7589433
|
PTEN
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16288286
10648629
17218262
12040186
15584861
|
IRS1
|
PIK3R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
12444011
11788580
14632132
14511371
19030972
16931767
7486683
21798082
11403293
12173038
8382612
12220227
12767520
10826997
16230374
7680095
23439647
19561084
16150444
12107746
10358772
11748924
12175651
7499365
7935461
15316008
9564850
16354680
16043515
12730242
11416002
7680644
23643389
21540285
8628286
15514089
11438664
8175658
9233603
1381348
25814554
|
PIK3R1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10527852
16799564
19442713
|
PIK3R1
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8596638
25241761
20713702
27107012
11733063
21825134
32814053
26496610
8139559
14729945
10358930
14665640
|
PIK3R1
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
9113989
8596638
21827948
12147247
11733063
22020336
24165795
31031754
14665640
|
PPP2CA
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11959144
|
MAP2K4
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11335711
|
PDPK1
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
16505477
21310943
11839738
31511386
9748166
25472878
25755284
15811957
15133032
11781095
19664995
15024053
15302935
15949469
14581488
28784722
17570831
18669648
11381116
20058876
17965192
19632318
20501830
|
SRC
|
PRKCD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
15851033
14970215
17569658
19366211
26876198
27203386
15961393
24211614
16982614
17570831
23329791
23329794
15541367
18550549
22689788
28637715
14715667
29422059
17658731
10319993
19138410
11927579
29452094
19632318
15337529
|
PRKCD
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11884618
11447289
19615955
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
PRKCD
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
15364919
17081983
16131083
15069075
15199052
23328071
16129690
12031982
15143153
18285345
14583092
16611834
15212693
15516986
16099428
12351658
|
RPTOR
|
RRAGA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RPTOR
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
AKT1
|
RPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
RPTOR
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RPTOR
|
HIF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
12150925
12777372
15755954
15854902
16469695
16915281
17991864
19299511
19864431
19942859
20484410
22025673
22841746
23087689
26159692
|
RPTOR
|
SQSTM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
20.0
|
1.0
|
ACSN
|
12150925
12777372
15340068
15755954
15854902
16252010
16469695
17991864
19299511
19864431
19942859
20484410
20531300
21981924
22025673
23087689
25002027
26159692
26587781
28574505
|
RPTOR
|
DEPTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11274345
11756498
12150925
12408816
12906785
15749884
15755954
16469695
16713974
17404308
17604271
17680028
18000759
18372248
18492954
19022819
19143636
19151919
19446321
19568798
19706736
19864431
20547845
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
|
RHEB
|
RPTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RRAGC
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
21816923
25561175
20006481
18497260
24337580
25446900
21981924
|
PRKAA1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21460634
18439900
|
RHEB
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17604271
15854902
19299511
16636147
24337580
15878852
17470430
19143635
16631613
12906785
18466115
25446900
|
AKT1S1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17604271
17510057
18030348
17386266
18215133
17517883
33230243
|
PRKAA2
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
18220336
19369195
18722121
18439900
20083114
19413330
18669648
|
AKT1
|
RPTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
29.0
|
1.0
|
Omnipath
|
18000759
21157483
11756412
11923280
16697215
20398329
17461779
18372248
15808505
20138985
20214616
19568798
15169778
19720745
17517883
10949026
11715018
19143635
17277771
18636226
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
RPTOR
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16183647
12087098
12604610
9465032
28249155
12150926
|
TRAF6
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11274345
12620219
14660645
15125833
15340068
15721744
16252010
17948050
18264787
18758450
18922473
19161412
20531300
21981924
25002027
26587781
28574505
|
TRAF6
|
SQSTM1
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11274345
12620219
14660645
15125833
15340068
15721744
16252010
17948050
18264787
18758450
18922473
19161412
20531300
21981924
25002027
26587781
28574505
|
SQSTM1
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15340068
16252010
20531300
21981924
25002027
26587781
28574505
|
NBR1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
29343546
16861740
20808283
15802564
24879152
25007327
19250911
12813044
21935636
|
WDFY3
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20971078
20417604
20168092
|
GABARAPL1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
21691068
25416956
31053714
16189514
32296183
21617041
19250911
|
MAP1LC3A
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
54.0
|
1.0
|
Omnipath
|
20061800
23022382
23459205
35044719
22963397
36036324
31053714
21045561
25921531
19250911
17580304
21628531
20204693
28740232
23640897
25686248
24100292
26075355
20562859
22658522
25984893
21460636
16286508
19427866
32296183
23989536
19021777
26268733
22714671
24998849
18653543
31366950
33436498
16169070
23239879
26754771
|
GABARAPL2
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17580304
20562859
23022382
17353931
24582747
25416956
33436498
31053714
16189514
32296183
21460636
19250911
21900206
|
TBK1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
24818040
25040165
29147513
28655770
31810986
28871090
25505069
32966780
27846364
31444413
27404485
34996837
32835772
24886973
30223576
29930914
29973599
27005665
22921120
25723488
25972374
33084718
|
MAP1LC3B
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
18083104
23022382
35044719
26413874
25416956
22434781
31053714
24023838
19250911
17580304
23333919
20452972
24668264
28085563
21900206
20562859
20010802
25007327
32296183
33302793
24582747
33436498
16169070
|
SQSTM1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
15870274
27458013
10747026
27681126
16079148
16189514
18382763
16874300
11244088
17389358
|
PRKAA1
|
STK11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
14511394
15579580
8779952
14985505
14614828
11018120
|
PRKAA2
|
STK11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
14511394
15579580
8779952
14985505
14614828
11018120
|
PRKACA
|
STK11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
11853558
17482548
11297520
17482549
10642527
|
STK11
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10642499
14976552
8910387
18693249
12764152
26489410
15509864
14614828
12413941
20160076
19197243
15980064
|
STK11
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
25763354
17875968
15987703
16107342
11035045
12077256
18321849
23379765
21779440
12297295
25336918
|
STK11
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
64.0
|
1.0
|
Omnipath
|
16434556
25792737
14985505
14976552
20489196
21062936
20656472
20616029
17255104
16041368
25696921
21399626
12391032
20160076
17244528
15980064
17054914
22517326
14532170
21918180
28694351
18693249
26771234
20801214
16600998
18195011
28723898
16912160
22039048
26068970
14614828
19884317
25679763
22575644
19197243
27864418
30022161
25683918
18303014
17287464
15327994
12764152
16054095
15509864
26506235
14511394
27181208
28625738
25874865
8910387
17276402
26247630
21680840
19414597
23418352
24289924
15383373
|
SUPT20H
|
ATG9A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19893488
|
TANK
|
TBK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
16127453
17568778
27035970
25409927
23286385
18307994
24488098
21419663
21988832
21903422
15210742
14743216
16189514
19820708
21931555
10581243
23007157
17823124
17468758
17327220
|
TLR2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
18070982
15247281
21220427
12140561
12138165
8837778
19592497
18347055
|
TRAF6
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
14660645
15125833
16252010
17948050
18264787
18758450
18922473
19161412
|
TRAF6
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
19675569
17947236
19843958
10882101
19521662
11259596
17079228
28024152
31885808
19112497
22924441
10094049
27501752
18922473
11518704
11809792
16517750
19232515
10702308
16410796
14633987
19820695
22851693
10921914
18758450
12496252
12609980
21822258
12242293
25963657
24434549
27249171
22643835
21245467
17965022
26038599
|
TRAF6
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10346818
17965022
15692051
17947236
|
UVRAG
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
BECN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
10604474
10949026
11085534
11704864
12667443
16179260
16227588
17106237
17446862
17891140
18097445
18612260
19265852
22039431
22093031
22166994
22421439
22836101
22885520
23030059
23064052
23301705
23377657
23430059
23725295
23850759
24070470
27754749
28645028
8929532
9765397
|
UVRAG
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
BECN1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
10604474
10949026
11085534
11704864
12667443
16179260
16227588
17106237
17446862
17891140
18097445
18612260
19265852
22039431
22093031
22166994
22421439
22836101
22885520
23030059
23064052
23301705
23377657
23430059
23725295
23850759
24070470
27754749
28645028
8929532
9765397
|
UVRAG
|
PIK3C3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10604474
10949026
11085534
11704864
12667443
16179260
16227588
17106237
17446862
17891140
18097445
18612260
19265852
22039431
22093031
22166994
22421439
22836101
22885520
23030059
23064052
23301705
23377657
23430059
23725295
23850759
24070470
27754749
28645028
8929532
9765397
|
UVRAG
|
PIK3C3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
PIK3R4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
UVRAG
|
ATG14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
16227588
17106237
17446862
17891140
18612260
19265852
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
SH3GLB1
|
UVRAG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18032918
17891140
21068542
|
UVRAG
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20562859
18957027
|
UVRAG
|
RUBCN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20562859
22423967
21062745
|
UVRAG
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
27203177
17106237
24956373
21311563
19050071
18843052
18641390
21597469
26496610
23954414
22081109
20562859
24034250
32296183
19270696
16799551
19172397
25490155
24056303
|
CAMKK2
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
16051629
22561688
21228273
34044797
24959379
17244528
15980064
23716691
25065674
15465812
34421352
12413941
19197243
18692468
33502468
34216621
23863464
34064003
16054096
16054095
15509864
33675805
20538596
19958286
25937278
34290400
34253170
23612973
22304913
|
MAP3K7
|
PRKAA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
18692468
15980064
|
PRKAA2
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18692468
16959574
19339977
14651849
|
PRKAA2
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21205641
19584320
|
PRKAA2
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18692468
19339977
14651849
|
ATG3
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20562859
17145710
17353931
16303767
|
ATG4B
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
20562859
17353931
19549685
14530254
16303767
16169070
32296183
15187094
21900206
|
ATG4A
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12473658
17347651
|
ATG7
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15197469
20562859
17145710
11890701
16303767
11096062
|
NBR1
|
GABARAPL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
19250911
|
IGBP1
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23892082
21988832
20092282
16085932
18782753
24484909
28330616
9647778
21454489
26496610
32296183
24145130
19156129
11371618
10441131
|
TBK1
|
OPTN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
27247382
29246869
29594070
27035970
21617041
18307994
22364875
29755463
21903422
26376340
29867991
23794264
26101267
26365381
21862579
27538435
25026213
25923723
29282133
29626651
29971063
30294276
30223576
20174559
26266977
23414517
27086836
23178947
22518139
27906974
25803835
|
ULK1
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
17145710
17353931
22885598
11146101
23043107
31053714
25126726
|
WDFY3
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20562859
24668264
|
ATG7
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20562859
17145710
11890701
16303767
11096062
|
ATG3
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11825910
17145710
16303767
20562859
|
NBR1
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
24879152
19250911
|
ATG4B
|
GABARAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
20562859
14530254
16303767
16169070
15187094
25126726
|
GABARAP
|
ATG7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20562859
17145710
11890701
16303767
11096062
|
BECN1
|
PIK3C3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
PIK3C3
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
BECN1
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
AMBRA1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21358617
22441670
23030059
23377657
23974797
|
DAPK1
|
BECN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11323415
17703233
18974095
19180116
|
DAPK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
19180116
19878311
26950124
23760551
30397185
25373623
28301741
29113343
19395874
29910671
29717115
24710488
26108642
|
VMP1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23316280
19056683
17940279
|
ATG14
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
19270693
19050071
25594178
19223761
18843052
27513923
26496610
23954414
23332761
22081109
20562859
26108642
25891078
24034250
23112296
32296183
24980960
19270696
21062745
20711182
25490155
|
ULK1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
26390974
25545884
28301741
29734735
29233870
30292171
28518135
29313410
24191236
26546165
24848530
25026281
26921696
25026296
25373623
17595159
16940348
26108642
29371398
25891078
23685627
24370004
26008601
28238651
30397185
29233871
24834848
29867359
|
AMBRA1
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
20562859
23974797
20711182
20417604
21358617
25438055
23954414
20921139
24587252
17589504
25499913
33562550
|
RUBCN
|
BECN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
22423967
25594178
22493499
26876213
19270693
19270696
|
BECN1
|
PIK3R4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
20562859
18843052
20711182
18957027
25490155
26496610
19270696
19050071
|
BECN1
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
18628207
36042481
19713971
19050071
16179260
25594178
21936852
18843052
24980959
28128446
25906440
26496610
26783301
23954414
19379691
23332761
20562859
23974797
24034250
16390869
24980960
19270696
25825496
19172397
20711182
23315026
25490155
24472739
17438366
23364696
|
TSC2
|
TSC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12150915
12172553
12869586
12906785
14551205
14651849
15342917
15611338
15851026
16556040
16636147
16678438
16959574
17604271
17680028
17693255
18198340
18481918
18692468
18974095
19022819
19027299
19339977
20146692
21533173
21621563
21708191
23030059
26597054
27328425
9069260
|
TSC2
|
TSC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
12150915
12172553
12869586
12906785
14551205
14651849
15342917
15611338
15851026
16556040
16636147
16678438
16959574
17604271
17680028
17693255
18198340
18481918
18692468
18974095
19022819
19027299
19339977
20146692
21533173
21621563
21708191
23030059
26597054
27328425
9069260
|
AKT1
|
TSC2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
DAPK1
|
TSC2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11323415
17703233
18974095
19180116
|
TSC2
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12906785
16636147
17680028
19022819
20146692
|
TSC2
|
TSC1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
12150915
12172553
12869586
12906785
14551205
14651849
15342917
15611338
15851026
16556040
16636147
16678438
16959574
17604271
17680028
17693255
18198340
18481918
18692468
18974095
19022819
19027299
19339977
20146692
21533173
21621563
21708191
23030059
26597054
27328425
9069260
|
PRKAA1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19339977
33271062
14651849
16959574
15261145
28591720
18692468
20363874
|
AKT1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
75.0
|
1.0
|
Omnipath
|
16873412
12820960
17018601
11756412
32308763
11923280
16697215
19690332
21893193
20398329
18372248
21177249
12438239
18466115
15808505
29042482
20138985
15342917
17597835
20214616
12271141
16702951
20837138
17570479
26844273
15169778
17386266
10949026
16288292
24590173
11715018
15661536
18636226
18411301
20028854
9812896
16636147
20169078
17680028
12172553
19664994
18707149
10722653
12150915
18570873
20832730
12364343
17052453
18283331
21666717
27451907
|
AKT2
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
12150915
12167664
12172553
19188143
|
DAPK1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
18974095
|
TSC2
|
RHEB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
15340059
15854902
23331499
16636147
12869586
17680028
21071413
20146692
12771962
20226003
12906785
12842888
|
TSC2
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
84.0
|
1.0
|
Omnipath
|
12167664
16424383
12511557
21134130
14551205
10915759
11741832
15340059
20166753
23331499
15342917
9580671
21071413
16464865
15851026
11290735
9809973
15851513
12869586
10807585
15963462
10585443
11741833
20412061
20226003
11175345
25263562
16339216
18411301
16636147
14651849
17658474
17693255
12176984
17077083
|
VPS39
|
SMAD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12941698
|
PRKCQ
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10652356
15214048
15536066
16606694
17544292
17548359
18784374
19201850
23077238
23433459
23474202
23886063
25960930
|
MAP3K7
|
MAP2K4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
PPP2CA
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18299321
17079228
|
PRKCQ
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23433459
19201850
23109003
17544292
18784374
15536066
16606694
23886063
26192618
20164171
17548359
17363905
23077238
10652356
25960930
23474202
15214048
|
MAP3K7
|
RAB8A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
34088839
32227113
32017888
31292254
32601174
33887226
30709905
|
MAP3K7
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16054096
16054095
15509864
19197243
17244528
20615388
18692468
15980064
|
MAP3K7
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15692051
17947236
11865055
17965022
17186025
|
MAP3K7
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
11477091
17301840
13130464
18855897
15125833
24699077
9278437
17363905
18641653
24403530
20060931
21133840
21614932
9891069
12738796
21232017
9851932
18264787
10391247
16799562
23109003
12620219
14633987
12709432
8177321
19161412
22941947
23681101
12556533
11280761
15082531
26192618
14660645
24958845
20164171
11460167
16603398
21041997
11274345
|
PTEN
|
AKT1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
22.0
|
1.0
|
ACSN
|
10753747
11747822
12040186
15721744
16288286
16982858
17218262
17409395
19440036
19847259
19945467
20609352
21084277
22179046
22465479
23732914
24030100
24254977
25364523
26597054
27328425
27572739
|
SRC
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24830552
22891331
12869565
21532586
|
AKT1
|
PTEN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
19903340
15987703
10790335
20596030
10592173
20605778
10866658
12077256
11035045
16107342
12297295
|
PTEN
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16288286
10648629
17218262
12040186
15584861
|
PTEN
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16288286
10648629
17218262
12040186
15584861
|
HRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RAF1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
HRAS
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
KRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
10958680
12750173
9516156
12932319
9665134
10783161
8805624
1386920
1639773
8340422
8601312
19595761
23331499
16041367
21071413
8332195
9446616
10882715
25852190
10531446
1996324
19029954
8503013
16093354
19541618
23153539
16293107
1708096
19933846
26721396
11136732
10205168
20802526
31980649
7760835
18775988
8307946
12917261
11134016
20080631
8180183
1990291
|
RRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8911690
8530446
10848612
8035810
9099670
19805522
7730360
|
PRKACA
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
19007248
11971957
20166139
18767875
20230923
9001246
10576742
23331499
20068231
7935389
18669648
18691976
9922370
15664191
19651622
12801936
9091312
10862777
9710607
11997508
|
AKT1
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
51.0
|
1.0
|
Omnipath
|
19197339
11971957
18767875
20230923
10576742
20068231
17570479
16189514
18669648
25241761
18691976
10576741
10618391
20688159
21745501
12087097
12801936
12048182
22798428
16854453
19058874
11997508
|
HRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
147.0
|
1.0
|
Omnipath
|
17145710
18273062
9523700
1639773
8601312
19595761
20133694
11032808
9154803
10882715
14654780
1996324
19222999
16301319
11948414
8530446
7969158
11313862
9150145
20080631
1990291
12750173
15031288
12932319
9665134
8805624
8340422
1386920
23331499
16916524
16041367
23180781
18988627
20178605
15688026
15664191
22169110
11733498
7862125
8180183
19063885
12391160
9144171
8035810
9020159
14724584
19696784
21779497
9261098
12173045
12620389
8628317
19914712
1708096
19933846
26721396
7730360
10205168
8332187
16803888
18775988
12917261
9099670
10545207
25684575
8670882
10783161
12379659
10887184
17569879
21071413
8332195
7523381
10531446
24929361
8503013
16093354
19541618
10369681
8911690
18073111
11136732
10922060
7760835
11134016
|
RRAS2
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12620389
10064593
11788587
16189514
10557073
10783161
|
PRKAA1
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
19651622
12801936
19007248
11971957
20166139
20068231
9091312
10576742
9710607
11997508
|
RHEB
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15854902
16803888
15150271
16189514
9001246
19222999
|
PPP2CA
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18039929
7604263
16680151
16239230
10995457
18042541
18588945
|
NRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
9867809
12750173
12932319
9001246
9665134
8805624
1386920
1639773
8340422
8601312
19595761
23331499
21071413
8332195
10531446
10882715
7811320
1996324
18988627
21779497
8636091
8503013
7766599
16093354
19541618
8180183
1708096
19933846
32296183
9525741
8876196
11136732
10205168
21478863
7760835
18775988
12917261
11134016
18641128
20080631
9488663
1990291
|
SRC
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
7692235
12551923
7517401
17097642
15258589
9689060
16189514
16630891
10998357
11376654
29063113
8876196
10205168
28846113
12952943
22592532
11134016
15710605
16170185
|
RAF1
|
MAP2K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
7565670
12750173
18799465
16364241
11909642
19219045
21988832
23331499
15342917
8933152
9671314
8393135
9808624
8223433
16189514
18988627
18669648
19541618
16293107
10969079
10567369
8157000
11136732
11948414
7898932
9069260
18039929
19369195
8607979
10327068
17116858
24746704
12920017
16129686
19058874
15466214
|
RAF1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
143.0
|
1.0
|
Omnipath
|
10757792
18337766
18799465
15342917
23728975
26496610
15866172
17053865
11242034
9351825
9677429
8157000
7992057
11948414
11604401
16129686
10677502
12695496
19197339
7565670
12750173
7936666
1326789
19219045
23331499
18556463
10976102
18988627
15485920
15175348
18691976
16407412
10409742
9311917
17192257
7898932
8621729
23934108
11684694
21336309
7624324
12920017
11948406
15466214
11042690
12907640
9032297
27169363
12876277
8933152
8223433
8248196
8131746
12594221
10969079
10567369
17979178
17724343
24746704
19058874
10958680
8090753
21071413
7731720
7873542
1330321
8503013
16093354
19541618
8394352
15466476
25155755
11136732
9069260
94178255
8607979
10327068
10359597
8039496
20212043
|
RAF1
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15485920
10523633
9819434
10486249
16189514
19058874
21139044
|
PDPK1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
PIK3R2
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
HRAS
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
SRC
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12695509
9626657
9020108
25157176
33413561
|
HRAS
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9069260
9113989
9235916
21779497
11739523
10545207
|
HRAS
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11525649
8137421
16810318
16713569
|
HRAS
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
9069260
9113989
8052307
24412244
17540175
9931431
11313862
14724584
10592173
9150145
8665852
10783161
|
RHEB
|
BNIP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
12906785
17928295
18466115
19022819
19143635
23087689
|
RHEB
|
DEPTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17680028
18466115
18492954
19022819
19143635
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
26597054
28216025
|
RHEB
|
BNIP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
12906785
17928295
18466115
19022819
19143635
23087689
|
RHEB
|
DEPTOR
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17680028
18466115
18492954
19022819
19143635
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
26597054
28216025
|
TSC1
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
12906785
14551205
16636147
17604271
17680028
17693255
19022819
20146692
|
AKT1
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
RHEB
|
DEPTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17680028
18466115
18492954
19022819
19143635
19568798
19864431
21157483
21981924
23087689
24795729
24973821
25002027
25730849
26159692
26597054
28216025
|
TSC1
|
RHEB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
17604271
16636147
20006481
17680028
20146692
14551205
17693255
|
BNIP3
|
RHEB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19136941
17928295
|
RHEB
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
17604271
17510057
16636147
12820960
12869586
17386266
19446321
19143635
17277771
18466115
|
DAPK1
|
PPP2CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
12598906
17703233
18582460
19543238
20495383
21172648
21172653
|
DAPK1
|
PPP2CB
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
12598906
17703233
18582460
19543238
20495383
21172648
21172653
|
DAPK1
|
TSC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11323415
17703233
18974095
19180116
|
SRC
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
28976934
21785723
17803936
|
DAPK1
|
STX1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12730201
|
DAPK1
|
DAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15611134
15367680
18239682
|
DAPK1
|
CAMKK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
18691976
15209507
|
CFLAR
|
ATG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12215447
15760909
17462996
19838173
23301705
23377657
23725295
24070470
26972597
|
CFLAR
|
ATG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
12215447
15760909
17462996
19838173
23301705
23377657
23725295
24070470
26972597
|
AKT1
|
CFLAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19339247
|
PIK3C3
|
ATG14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG14
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
PIK3C3
|
ATG14
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ATG14
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
ULK1
|
ATG14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
27938392
29371398
30397185
23685627
29313410
|
ATG14
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18843052
19270693
22493499
19050071
|
PIK3C3
|
PIK3R4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
PIK3C3
|
PIK3R4
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
17106237
17446862
18612260
22093031
22166994
22421439
22885520
23030059
23301705
23377657
23725295
24070470
27754749
28645028
|
HIF1A
|
PIK3C3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15806152
16682453
15833446
16618748
|
RUBCN
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
19270693
22423967
21062745
|
PIK3R4
|
PIK3C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20562859
27411398
8999962
18957027
21575909
|
ATG5
|
ATG12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG5
|
ATG12
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG5
|
ATG3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG12
|
ATG5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11825910
20562859
17145710
12890687
17353931
22342342
9759731
9852036
23202584
11265251
12207896
12482611
|
ATG10
|
ATG5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15197469
16963840
10508157
12482611
|
WDFY3
|
ATG5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20417604
|
ATG5
|
ATG16L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
20562859
23262492
22342342
20639872
23392225
12665549
23202584
18448665
25484072
28594407
10406794
21575909
22847423
|
ATG12
|
ATG3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
22093031
22166994
23030059
23301705
23725295
24070470
24257061
|
ATG10
|
ATG12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17145710
16963840
12482611
17353931
10508157
11265251
18704115
|
ATG7
|
ATG12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
20562859
15197469
11265251
11890701
9759731
11100732
18704115
11096062
12482611
|
CDH1
|
CTNNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17145710
7542250
19016843
25468996
9326449
16212417
11960376
11801604
8227214
10381631
16219695
9700170
24336504
22750944
9233779
11226248
|
CDH1
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17496910
19029934
22370635
16099633
23343194
19734908
10744074
16039586
22203675
19171760
22007144
19619488
17143292
|
HIF1A
|
BNIP3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14612449
11457733
18752464
17878221
|
HIF1A
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19144925
17220299
17488804
14726529
15277220
|
HIF1A
|
BNIP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20864819
17848618
11559532
20332243
19745228
17513511
11550088
10922063
12879018
|
HIF1A
|
TLR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19828020
18159247
|
HIF1A
|
AURKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18562694
19828020
|
RB1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15674338
|
HIF1A
|
BNIP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16585195
19136941
18054315
11559532
|
SRC
|
PIK3CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
12682286
15314172
20861220
18657504
11689445
12431978
25587652
11044445
22266855
11029403
11029009
|
PRKCQ
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
16488589
6321473
8321321
12845332
11313945
12040186
19568798
15567848
14585353
|
PTPN12
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
19595712
18482983
|
PRKACA
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
19651622
17081983
20166139
2474754
18088087
15546918
19664994
11804588
|
PTPN2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15696169
18948751
27611995
22080863
|
SRC
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12750372
10592173
17275257
10830300
|
SRC
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21780115
15032589
11526404
23109003
22880054
10488096
|
SRC
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
20643654
14585963
16314505
11481331
15212693
12738763
1148133
15302935
|
SRC
|
PPP2CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
25003662
10978272
21292165
23796501
24676687
22771321
24395787
17635907
26378614
16286244
27013170
23222956
25726524
24997451
31992581
12921784
1325671
17303700
23251465
20558158
21554241
23926298
25931585
22299660
18208556
21791414
23436320
32130916
17394530
|
SRC
|
RRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17474147
15212693
10570155
11682467
|
SRC
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17389395
15212693
18691976
7559478
7493944
7537849
20068231
23472139
8550552
17016520
8940173
9480911
|
SRC
|
ATG9A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
27934868
|
SRC
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11445557
25241761
23242524
18283331
12600984
|
AKT1
|
TSC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
AKT1
|
TSC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
12167664
11756412
11923280
16697215
20398329
18372248
15808505
20138985
20214616
15169778
10949026
16288292
11715018
18636226
9812896
17680028
12172553
10722653
12150915
18570873
20832730
17052453
|
PDPK1
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10652356
11687500
11747822
12670391
15214048
15536066
15802604
16606694
17544292
17548359
17680028
18784374
18802401
19109239
19122654
19201850
23077238
23433459
23474202
23886063
25960930
|
KRAS
|
PRKCQ
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
Reactome
|
23943869
26590425
9436858
11585916
29311131
20802526
25713064
16483930
24033119
27697864
|
PRKCQ
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15364919
17081983
26956053
25381390
17709744
|
PDPK1
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
PDPK1
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
PDPK1
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
11687500
11747822
12670391
15802604
17680028
18802401
19109239
19122654
|
IGF1R
|
PDPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20044479
11054117
17570479
20643654
|
PDPK1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
15743829
15191648
10679787
23331499
19203586
15718470
26491696
26937223
9374542
24169049
15890450
28589878
9512493
12048203
10822383
12434148
20059950
11134526
|
PDPK1
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9512493
12162751
10208883
23603119
19203586
15718470
|
PDPK1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
70.0
|
1.0
|
Omnipath
|
17081983
12429015
15208671
18326039
16286006
11438723
21561857
18802401
19864428
16099428
7545671
7489717
27149630
15388791
12183455
10601311
9465032
26582459
29257917
12967624
24604594
15718470
9427642
10209156
23769967
12586835
15809305
9218810
11500365
14560963
9271440
20932932
12370290
11914378
11684675
17680028
14993219
19570988
9445476
|
PDPK1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8131746
8394352
15175348
15466476
94178255
7731720
7624324
8157000
8039496
8621729
|
PDPK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
156.0
|
1.0
|
Omnipath
|
15505410
12538620
12176337
19951971
24352480
11752451
19401591
11369519
10698680
10601311
15718470
24950409
20481595
24169049
10570282
16798838
14993273
11500365
9368760
19844585
17680028
7637810
9169478
26256536
7722458
9094314
12750173
11438723
18802401
9252186
23331499
18456494
9104825
10592173
16189514
20361045
18988627
11278835
20163786
20333297
20041157
12808134
19602588
8630736
10207050
11241670
10438924
9868760
25912234
20153221
25582703
11445557
21775285
12149249
14666721
18596232
9512493
23397142
11809791
12167717
21798082
16033886
10679787
16787925
29562639
15550174
21071413
8978681
10833263
19203586
10226025
26937223
14500673
20161206
11136732
11825911
11042193
9642236
22569334
18662999
9736715
12242303
11313365
11598012
11134526
|
PDPK1
|
MAP2K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15175348
15466476
|
PDPK1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
16026785
20732331
15481030
22493239
10698939
9707564
8706898
20137943
21774789
17192257
22154087
20481595
12372837
16765046
|
PDPK1
|
RPS6KB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
15209375
17680028
16286006
12713446
11733037
11500365
14560963
18802401
20932932
9445476
|
IGF1R
|
IRS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10086337
10826997
11274345
12175651
12444011
12556535
12655147
12767520
16931767
17145802
17673906
19030972
21540285
24103846
24782617
|
AKT1
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17570479
17640984
10497255
|
PRKACA
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17360977
12624099
|
RPS6KB1
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
47.0
|
1.0
|
Omnipath
|
21283818
17081983
16953237
24931005
11287630
15249583
27898058
16914728
25379019
23565163
15364919
15533996
19121779
9312143
17709744
20074531
22523661
23958494
16129690
23006971
23898460
26474286
28342808
17507185
25813876
26926384
15306821
20932932
34013180
15199052
18498745
18952604
18220336
12006582
19369195
29496905
27889207
26666849
|
MAPK9
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11160134
9335553
12417588
14579029
|
IGF1R
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
7541045
12444011
19030972
10082579
16931767
21798082
12220227
11259577
12767520
10826997
23331499
17827393
7504175
21071413
7559507
11572799
27856640
12175651
17570479
15829723
18988627
15629149
11557037
20670944
8530377
21540285
8776723
25886138
8662806
|
MAPK8
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
15001544
18728222
26882989
12409308
10592173
15314024
12417588
15613682
14579029
10722755
26538579
29207597
15199052
12351658
16055440
11606564
12510059
15212693
|
INS
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
25309812
25472611
23891856
20150288
29069585
24036112
21518983
11160134
19357636
22198320
17579213
21677282
11684411
23983791
28955049
25760026
21850561
22832498
19808019
22698915
23815272
18443205
20601126
16150913
25383313
27695421
23115649
22728334
19752148
19171749
27819676
16516141
22418434
19542202
25381390
22516431
24763529
26866272
23695665
23431498
|
IRS1
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
16931767
12175651
|
IRS1
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
11120660
7559478
10358772
16931767
12730242
12175651
7499365
15316008
|
IRS1
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
9415396
16931767
12175651
10417350
7542745
25814554
|
IRS1
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
16354680
16150444
16931767
10592173
12175651
1380456
23643389
1381348
11313948
9374521
20966354
9624169
|
IRS1
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12767520
10826997
12444011
21540285
19030972
16931767
14623899
11416002
12175651
|
INS
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
1851182
18988627
|
IGF1R
|
IRS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9553137
18988627
11316748
|
IGF1R
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17496910
25241761
9415396
9524259
|
IGF1R
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
8662806
9852124
10471495
|
AKT1
|
RRAGA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
AKT1
|
RRAGD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
INS
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
29432553
23912456
11679435
23866690
17335965
24646332
23798298
|
PIK3CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25793261
19117013
21041639
24950409
21816939
|
PPP2CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
21159657
26256536
15743829
10026142
20452955
11438723
18559511
11839802
19996169
19216069
16406523
10995457
18042541
19556239
18588945
16680151
11087733
18160256
15367694
18039929
18077353
11812651
16044149
20360384
12637511
|
PPP2CB
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15367694
11087733
18039929
19216069
18077353
19556239
19996169
10026142
10995457
18042541
20452955
18559511
8650155
18588945
16680151
11812651
20360384
16406523
|
TBK1
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21329883
21464307
21106850
|
AKT1
|
MAP2K4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
15911620
15998799
17570479
30680530
11707464
|
AKT1
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24947355
18250332
16332683
18955969
|
AKT1
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20016067
23331499
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
AKT1
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
19376078
16340011
16083285
26506913
27784766
24467442
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11943559
23331499
25241761
21071413
12183455
15149849
11438723
|
AKT1
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
63.0
|
1.0
|
Omnipath
|
18000759
17081983
17510057
12820960
21157483
11756412
11923280
16697215
19690332
19446321
20398329
17461779
18372248
19413330
15808505
20138985
23415227
20214616
12524439
20068231
14973226
19568798
18669648
17329361
15169778
12869586
17386266
19720745
17517883
11352916
10949026
11715018
19143635
17277771
18636226
19651622
9812896
17680028
19151919
10722653
20832730
18570873
17052453
12408816
11274345
|
PRKACA
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23861900
16222244
16246726
33744274
29764989
26165940
11039908
17545617
27242098
26481147
28869606
26134678
33988677
26831064
33760847
16083426
17895985
|
ATG7
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
22170151
16303767
|
ATG7
|
MAP1LC3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
20562859
17145710
11890701
16303767
22170151
11100732
|
ATG7
|
ATG10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15197469
11890701
12482611
9759731
11096062
|
ATG7
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15197469
11825910
|
ULK1
|
AMBRA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23524951
25438055
20921139
|
MAP1LC3A
|
ATG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20562859
25503391
19838173
16303767
22170151
|
ATG3
|
MAP1LC3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
20562859
11825910
17145710
16303767
11100732
11265251
17227760
|
IRS2
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10594015
19109239
9651378
15715521
|
IRS2
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9113989
22810696
9374521
|
SEC22B
|
RAB1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
21532587
24917561
20966969
17287728
|
SEC22B
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
INS
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20338882
25304263
30179516
23832510
23801578
22307032
20041157
24725432
|
RAB1A
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
10903204
11306556
23378591
9150144
10679020
11285137
23698585
11927603
16624868
|
PPP2CB
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
18039929
19216069
10026142
10995457
18042541
20452955
18559511
8650155
18588945
16680151
16406523
|
PPP2CB
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
PPP2CA
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
PPP2CA
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18039929
16680151
1716348
10995457
18042541
18588945
20626350
|
PPP2CA
|
MAP2K2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
18039929
16680151
10995457
18042541
18588945
20626350
|
PPP2CA
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16109716
2826472
16899564
11438723
11124802
10200280
|
PPP2CA
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10921877
21159657
16885030
12370081
19890961
16916641
10702384
21376459
|
PPP2CA
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
15367694
18039929
19216069
10026142
10995457
18042541
20452955
18559511
18588945
16680151
16406523
18160256
|
AKT3
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20016067
17680028
20214616
17688959
20398329
16537363
17052453
19575820
|
PRKACA
|
PTPN12
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
19651622
18767875
20068231
7520867
94349924
18669648
|
PRKACA
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
12764152
17023420
27784766
|
PRKACA
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
2847175
1847804
8132598
19144319
12529267
14741364
|
NBR1
|
MAP1LC3A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23022382
21620860
19427866
19250911
21935636
|
ATG4B
|
MAP1LC3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
20562859
18083104
19549685
19322194
14530254
20010802
15355958
16169070
24023838
32296183
15187094
11038174
21900206
|
ATG4B
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
20562859
19549685
14530254
20404487
32296183
|
BET1
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
9094723
9647643
24119662
10747087
23378591
16303754
19164740
9307973
25406594
17038314
8663406
|
STX5
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
9094723
9647643
24119662
10747087
23378591
16303754
19164740
9307973
25406594
17038314
8663406
|
GOSR2
|
YKT6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22013193
19758564
24119662
19164740
|
GOSR2
|
GORASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
9094723
9647643
24119662
10747087
23378591
16303754
19164740
9307973
25406594
17038314
8663406
|
PIK3R3
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8596638
22402981
9415396
11733063
26496610
25814554
|
NRAS
|
PIK3CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
8052307
7820549
9150145
8665852
21779497
|
PIK3CA
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
15854902
19225151
20097763
21123297
30021155
24990947
20068231
19079619
15809305
20599721
14623952
11279232
34518212
33800846
18669648
|
KRAS
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
NRAS
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RRAGA
|
RRAGC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
MAP1LC3B
|
NBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
20562859
23022382
21620860
24879152
19250911
|
MAP1LC3C
|
NBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20562859
21620860
19250911
23022382
|
NBR1
|
GABARAPL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
20562859
21620860
19250911
23022382
|
MAP2K4
|
MAPK9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
17143273
7600581
11489946
10748139
18855897
14699111
10791986
17761173
18083107
12788955
9305638
22730327
23331499
19534553
23047924
11062067
21614932
12738796
15998799
11389443
18988627
9733714
11847100
16153436
21900206
11242034
14523011
26370088
10499589
16076903
7992057
7600582
9860979
17192257
15755722
12133933
19369195
9841871
10385525
12354380
9448004
12624093
11274345
11099046
|
MAP2K4
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
91.0
|
1.0
|
Omnipath
|
17143273
10713157
11489946
7600581
8702918
17145710
13130464
23416355
10748139
8805275
18855897
10791986
9108083
19690332
95141073
18083107
9724739
12788955
9305638
23331499
19534553
15068801
7839144
10958661
21071413
23047924
11062067
21614932
9808624
12738796
15911620
15998799
9891069
11389443
18988627
9733714
11847100
18669648
16153436
10521444
15302099
16282370
11242034
14523011
12709432
26370088
9661668
10499589
7652575
16076903
7992057
16440308
7600582
17192257
9860979
15755722
12133933
16533805
19369195
9312068
9207092
10385525
12354380
12917261
8910292
9487126
9448004
10962008
12624093
11274345
11099046
|
MAP2K4
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
17143273
11489946
10748139
18408005
18855897
17761173
18083107
8974401
12788955
10715136
23331499
23047924
11062067
21614932
15911620
12738796
11389443
18988627
12624093
11847100
11242034
26370088
16076903
12133933
19651622
12354380
14523011
11274345
|
MAPK8
|
RPS6KB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21988832
17570479
11279232
23816567
|
KRAS
|
MAP2K2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
RB1CC1
|
ATG16L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20562859
23262492
23392225
24954904
24100292
|
AKT2
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
17329361
19651622
17081983
17386266
17517883
12524439
11352916
20068231
18372248
19413330
17277771
14973226
18669648
23682635
|
AKT3
|
AKT1S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17440074
17517883
18372248
17277771
|
CAMKK2
|
PRKAA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
14985505
21918180
8910387
16054096
16054095
15509864
19197243
14614828
23625915
17244528
18692468
15980064
14511394
23583109
|
PRKAA1
|
ULK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24820971
23372762
28295473
21460634
19584320
21205641
21258367
28389629
34421918
34224814
25980607
32978258
|
NRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
KRAS
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
PIK3R2
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
PIK3R2
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
31135801
24897931
8665852
17998941
11136978
21779505
8052307
12121613
1716764
26085527
21779497
12094235
|
ATG101
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20562859
23392225
19597335
|
ULK1
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
25686248
26118643
19211835
|
ULK1
|
ATG9A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
25266655
27934868
|
MAP1LC3C
|
WDFY3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24668264
|
WDR45
|
ATG2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
28561066
31412244
20562859
|