Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
SNAP29 VAMP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23466629 23578367
SNAP29 STX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23466629 23578367
SNAP29 STX17 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 23466629 23578367
SNAP29 VAMP8 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 23466629 23578367
STX17 VAMP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 23466629 23578367
STX17 VAMP8 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 23466629 23578367
GABARAP STX17 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BAKOR STX17 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25686604 31671609 30584088
PTPN12 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 28065597
CDH1 SRC â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
C5ARL STX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR TMCO3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
TMCO3 STX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VPS41 STX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24554770 33422265
STX17 VPS39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24554770 33422265
SNP29 STX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VPS11 VPS33A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
VPS11 VPS16 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
VPS11 VPS18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
VPS16 VPS18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
VPS18 VPS33A â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SNP29 VAMP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25416956 32296183 30833792
STX5 VAMP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 32296183 30833792
SNP29 VAMP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33947832 33961781 23217709 25419848
VPS16 VPS33A â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
VAMP8 STX17 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31251111 33422265 23217709 25419848
SNP29 VAMP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 12853575 26186194
CDH1 CTNNA1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
SNAP29 VAMP7 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
VPS41 VPS11 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 26463206 28514442 28931724 33422265
STX3 SNP29 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 9852078 32296183
TLR2 EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 17126326 25402006 24658140
MLH3 MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 10615123 11292842 27229929 24443562 32814343
SNP29 STX17 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 23217709 25419848 9852078 33422265
SMAD4 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22775504 17452626 24625091
EGFR PTPN12 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
STX3 VAMP8 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
SNAP23 STX3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
VPS33A VPS16 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 29778605
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
VPS33A VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS16 VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS18 VPS39 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
VPS39 VPS41 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
MSH2 MLH1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 12799449 30770470 10748159 25241761 31843968 10783165
MLH1 MSH2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
VPS16 VPS11 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 11382755 26496610 23901104 26463206
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
VPS11 VPS33A â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
VPS11 VPS16 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
VPS33A VPS41 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS11 VPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS11 VPS39 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS11 VPS41 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS16 VPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS18 VPS33A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
VPS16 VPS41 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
VPS18 VPS41 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
VPS16 VPS33A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDH1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17496910 19029934 22370635 16099633 23343194 19734908 10744074 16039586 22203675 19171760 22007144 19619488 17143292
CDH1 CTNNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17145710 7542250 19016843 25468996 9326449 16212417 11960376 11801604 8227214 10381631 16219695 9700170 24336504 22750944 9233779 11226248
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
PTPN2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15592458 15588985 9488479 10488121 11514572 11479308
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
MLH1 MLH3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15703371 16612326 16697054 18157157 18406444 19847258 20478261
PTPN12 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19595712 18482983
PTPN2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15696169 18948751 27611995 22080863
VPS39 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12941698
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368