MAPK14
|
FOS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18253836
|
IFNG
|
CAMK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
HRAS
|
DPYS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ERBB3
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
FOS
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10903433
|
BRAF
|
MAP3K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16888650
5218924
|
MAP3K1
|
FLNB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19270716
7288582
|
BRAF
|
MAP3K1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16810323
5218785
|
FOS
|
NFATC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15073183
23619911
|
FOS
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19022561
|
DLST
|
PAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HCK
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
NLRP3
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
BLVRA
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0800750105
18463290
|
KSR2
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22510884
8396417
|
ERBB3
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
17496910
|
NFATC1
|
ACP5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20831919
21413932
|
NR4A1
|
CYP19A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17574328
15486232
|
ATP6V1B1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
P4HA3
|
NF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NT5C
|
FLNC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
COX5A
|
NDUFB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
FLNB
|
FLNC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22863883
19293945
|
ATP6AP1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
HRAS
|
BRAF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
34591642
|
HRAS
|
BRAF
|
â—¼ PROXIMITY
|
✅
|
|
0.87
|
0.87
|
mint
|
30194290
|
HRAS
|
NF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
NDUFB11
|
NDUFB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
MAPK14
|
MKNK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
ATP6AP1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
KSR2
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
BRAF
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
ATP6V1B1
|
ATP6V1D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1H
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
FGA
|
FGG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
ACTR2
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
BRAF
|
MAP2K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ATP6V1D
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
NCF1
|
MAPK14
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
16778989
25877926
14530365
27558335
|
DUSP2
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
8626452
7535770
|
MAPK14
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
15187187
18039929
12738796
11274345
12697810
|
MAPK14
|
EIF4EBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
35.0
|
1.0
|
Omnipath
|
17081983
11691836
18767875
12665511
17043358
19413330
10405182
19664995
10942774
9092573
20068231
9465032
11777913
18669648
8083223
12105188
17287340
9405468
12370290
19651622
10779345
10364159
12912989
|
MAPK14
|
MKNK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
15187187
20936779
18039929
26186194
23331499
25241761
23602568
12897141
9155017
10922375
12738796
17570479
11274345
15550948
|
MAPK14
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
15649893
20516082
16648474
12944472
11997522
10788511
15304486
10747897
17255949
10652349
11274345
12697810
|
IFNA14
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
PDGFRB
|
PDGFRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
ACSN
|
15099563
17145802
17496910
18633355
24359404
|
PDGFRB
|
PDGFRA
|
â—¼ SHARES_COMPLEX
|
|
|
5.0
|
1.0
|
ACSN
|
15099563
17145802
17496910
18633355
24359404
|
PDGFRB
|
PDGFRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
21071413
2161888
2542288
7523122
1847074
16189514
11331882
10417313
|
NFATC1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9374532
11994444
12842891
12836278
|
FOS
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19285436
16713974
7759501
8756632
12842891
12432566
|
HRAS
|
ERBB3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
NF1
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
8628317
19777070
26635368
24431436
19718661
|
HRAS
|
PIK3CD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9069260
9113989
9235916
21779497
11739523
10545207
|
HRAS
|
BRAF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
17145710
7706312
14970219
18567582
12932319
8073291
1386920
23331499
8601312
9154803
18988627
8668348
21779497
19541618
19933846
17563371
18098337
16803888
26165597
24441586
16135787
12917261
15710605
10545207
|
NDUFB5
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFB11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFV3
|
NDUFB11
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFV3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFB5
|
NDUFV3
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
IFNA16
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA21
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
CYBB
|
NCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
CYBB
|
NCF1
|
â—¼ SHARES_COMPLEX
|
|
|
25.0
|
1.0
|
ACSN
|
10679059
10714681
11062502
11146654
11385609
11747822
11907067
12626562
12740575
14697347
15169870
15184873
15536084
15927447
17517963
18423981
18809714
19372727
19380816
19732719
21178402
21383238
22157818
22827577
27331412
|
MAP3K1
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8385802
12048245
8131746
17110930
8034665
8019005
10969079
12456688
|
NAMPT
|
INSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
28490838
15604363
|
MAP2K1
|
LAMTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21779496
9733512
12479806
15118098
17178906
15547943
|
LAMTOR3
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
11266467
15547943
9733512
|
BRAF
|
MAP2K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
67.0
|
1.0
|
Omnipath
|
20212043
7706312
25437913
9560161
7936666
14970219
18567582
18332145
8413257
23331499
15342917
21071413
7731720
7873542
26496610
10976102
18988627
17667937
16255777
8131746
16888650
15485920
8394352
15175348
15466476
19541618
25600339
25155755
17563371
16810323
8157000
17979178
18039929
94178255
23934108
7835430
7624324
24746704
16135787
7935374
8039496
8621729
|
BRAF
|
LAMTOR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21779496
9733512
12479806
15118098
17178906
15547943
|
MAPK10
|
NFATC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16648474
10978313
10652349
11274345
|
OXT
|
AVPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
9334232
10519430
9884074
9322919
12660315
9264324
9459574
8106369
|