Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2AX SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H2AX H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
NPAT CASP8AP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17003125 0604227103
H4C6 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
E2F1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12629508
HINFP H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17974976
BCAS2 BUD13 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CHAF1A CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
E2F3 CDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8033208 7958856
CDK2 WEE1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 1396589 11585773
HINFP CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14585971 19590016
CDK2 TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25688093
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
CRK TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
E2F2 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7958836
E2F1 NPAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12665581
E2F1 E2F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15014447 18319725
E2F2 NPAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12665581
E2F4 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
TP53 E2F3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20428827
E2F3 NPAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12665581
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
E2F4 NPAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12665581
E2F4 WEE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14532282
E2F4 NPAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 12665581
GAPDH POU2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12887926
HINFP TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
IK SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STIP1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12138177 11779500
CCNE1 NPAT â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9472014 15555599 10995387
H2AX CRML â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
H2AX NPAT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASB7 NPAT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDK2 H4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23455922 21840486
H4 NPAT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRML NPAT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ASB8 NPAT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CDK2 E2F4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 33961781
ZN219 MBD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN219 NPAT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN219 RBBP7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CCHL NPAT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
WEE1 CRK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11839808 16713569
RBBP7 NPAT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HCFC1 E2F1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20622854 17612494
E2F1 E2F3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 35140242 24981860 20106982
HINFP NPAT â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15988025 14585971 22288532
TP53 S100A4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 19740107 7256480
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
INCENP TPX2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
S100A4 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CCNA1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16774918 10022926
TRRAP E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11418595 9708738 18542057
GATAD2A MBD3 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F1 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11245432 7969176 8458319 1530885 9199321
TP53 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530187 15456866
H4 RBBP7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9427644 18571423 30804502 20953179 19862764 28514442 29104064
E2F4 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14576826 10208422
HCFC1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17612494 19763085 23629655
HES1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15467735 19891787
E2F1 NPAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527885 12665581
E2F3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
E2F4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576826 10766737 18319725
HES1 GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GATAD2A RBBP7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
MBD3 RBBP7 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
H2AX H4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26095369 24981860 20224553 18285460 27248496 28514442 20000738 16522924 30021884
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
CREBBP STAT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8978686 23455922 15980415 24771265 15670215 15514162 26496610 20837141 25728284 9891079 33854239 10330164 8867812 23602568 14681455 11433299 16431923 9716181 20587660 28137908 14701826 14536078 17361108 33854235 10827081 8662825 9472014 25852190 16223725 9192873 11940657 12839982 11132966 10359664 7799941 21092281 8647086 8756624 19631451 28514442 21372285 9660939 17431037 17254967 29439025 19470470 21241890 9840943 17970072 1388288 18559665 12800980 15004009 26186194 24358021 23853094 12529437 15557281
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNA1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17660363 15840440 16135794 18590585 7575488 17303408 9736735 15133492 15558010 15123636 9556498 10022926 16213134 11980909 16123593 11739724 15279786
E2F4 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 11799066
E2F1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 21653699 19564413 20220142 23518498 8668155 7623816 1059478 14618416 20410059 12565705 17471231 23543735 10594784 24335704 22185819 21454377 11526499 10504464 8618861 8649818
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
WEE1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7575488 18590585 17303408 18319725 17660363 15279786
CCNE1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7575488 18590585 18687693 9315635 17303408 17660363 12006580 11420722 15279786
WEE1 CDK2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15279786 17303408 17660363 18590585 23508805 23897299 7575488
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
WEE1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 58.0 1.0 Omnipath 17303408 24927813 25458954 19690332 16497976 18083107 30266203 15279786 15302935 15632290 12181445 17389395 17095507 7575488 19534553 7743995 18452278 12912980 22999936 21900495 24419005 1396589 18590585 10896159 18691976 15144186 20462953 12972555 16177568 17660363 17192257 11029659 34156324 17545210 19369195 26240362 19664994 11585773 25361894 20465818 17016520 15659558 18212344 13678583
CDK2 NPAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10995387
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
STAT1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15695802 10848577 9773981 8848048 9037008 16481475 15894584 8986769
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
E2F3 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14576826 7958836 12063292
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
E2F4 E2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 21247883 9149906 15718499
NPAT HINFP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22288532 18850719 17974976 14585971 15988025
HINFP NPAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17163457 19170105 19590016 17096384 17974976 14585971 17577209
TP53 S100A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19740107 15116098 23752197 20591429 20070253 11527429 12942774 31837246 11278647
S100A4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19740107 15116098 23752197 20591429 20070253 11527429 12942774 31837246 11278647