MIB2
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25565632
31366726
|
UBE2D2
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25565632
31366726
|
CYLD
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19131965
23010170
|
CYLD
|
IKBKG
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
12917691
15620648
|
CYLD
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17981138
19131965
|
CYLD
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29291351
18332137
|
MIB1
|
DLL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16140393
21985982
|
RIPK1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10880512
5212735
|
TBK1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
NEURL1
|
JAG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
15380241
|
NCL
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
UBE2D2
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25565632
31366726
|
TRAF2
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IKBKG
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
FA9
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
MAVS
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
30410068
18636086
|
CYLD
|
MIB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31462741
31067453
|
IKZF1
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IKZF5
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
P2RY1
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
NUPL1
|
MIB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
TNFRSF1A
|
TRAF2
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
10795740
|
RIPK1
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33654169
22848449
28900035
17981138
21408173
|
MAP3K7
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
CYLD
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
TNF
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
23815148
8432069
|
CFLAR
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9208847
32313199
16713569
10837247
16189514
|
TBK1
|
MIB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31462741
21903422
|
MAP3K7
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
BCL10
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAVS
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAP3K7
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
BCL10
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
11466612
32296183
25910212
10753917
16713569
25416956
|
TBK1
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18636086
25923723
29755980
|
IKBKG
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
TBK1
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33372174
24643253
21903422
32511263
21813773
25636800
23028469
29125880
28346439
32366851
29743353
16153868
|
CYLD
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
IKBKG
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
MAVS
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
DLL1
|
MIB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
TRADD
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23429285
30561431
21724995
27768232
8612133
16603398
24735611
|
TRAF2
|
UBE2N
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
IKBKG
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
TBK1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
TNF
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
TBK1
|
AZI2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29251827
21903422
30420664
29395067
14560022
14743216
23286385
21931555
27620379
17568778
32707033
|
MAP3K7
|
BCL10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
17158449
15327770
10882101
|
MIB2
|
JAG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15920166
|
UBE2N
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17965022
17079228
10702308
|
UBE2N
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18981220
14713952
|
TRAF2
|
RIPK1
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
10795740
|
TRAF2
|
RIPK1
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18621737
|
TNFRSF1A
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
IKBKG
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
RIPK1
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
TNFRSF1A
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
AZI2
|
TBK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
TRADD
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
AZI2
|
TBK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17145710
21903422
19820708
14743216
21931555
14560022
|
IKBKG
|
BCL10
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11280761
11356195
11460167
12133805
12356734
14660645
15145317
15199157
15485931
15536066
16809782
16818229
16970925
17052756
17237376
17254973
17301840
17363905
17462996
17485448
17693255
17948050
18264101
18264787
18716620
19302050
20138012
20300203
20685844
21133840
21199863
21217011
21232017
21807870
21873235
22435554
23086447
23422957
23430059
24560716
24699077
24958845
2649237
28462531
|
BCL10
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
14695475
19897484
18287044
27070702
17363905
|
TRAF2
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
RIPK1
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
CFLAR
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15024054
20696707
19278658
10837247
19416807
21235526
|
TRAF2
|
CFLAR
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
RIPK1
|
CFLAR
|
â—¼ SHARES_COMPLEX
|
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK1
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
TRAF2
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
CFLAR
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12887920
11002417
17047155
10837247
|
CYLD
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
12917691
23405219
17851586
|
CYLD
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
21988832
15341735
15870263
22990857
12917689
12917691
16627981
20932475
26802121
12917690
|
TNF
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
TRADD
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TRAF2
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
RIPK1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
MAP3K7
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
TNF
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
TRAF2
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
RIPK1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10880512
21383699
21458669
14653779
10980203
17702576
9927690
16603398
16547522
16965765
10755617
|
MAP3K7
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
24911653
11477091
17301840
18180283
19909372
15125833
24699077
17363905
16356855
18641653
24403530
18079694
18223652
14514672
17496917
19531477
20300203
11325957
21133840
21232017
18264787
9744859
10391247
16799562
15836773
10702308
23109003
12620219
14633987
17363973
19161412
22941947
23681101
17047224
29145629
11280761
16301747
15082531
26192618
14660645
20038579
24958845
15327770
20164171
11460167
16603398
21041997
|
TNFRSF1A
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16189514
10755617
|
MIB1
|
JAG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
25747658
20720151
21071413
12530964
18043734
|
TRADD
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TRAF2
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
RIPK1
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TRAF2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
12547194
20038579
14633987
14743216
17384642
|
MAVS
|
TBK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
21813773
15210743
16127453
33372174
17020950
25636800
21903422
15210742
16753195
16306936
12702806
24643253
16177806
27419230
16153868
16858409
29743353
17468758
17327220
|
TRAF2
|
RIPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
RIPK1
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12556535
12655147
12738796
14730360
15170913
15592525
17462996
17496911
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23070005
23850759
24378531
26587781
26653790
28574505
28765050
9379049
9582321
|
RIPK1
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
RIPK1
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
78.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11668179
11875494
12048245
12556535
12646658
12655147
12738796
12811837
12887920
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
16713974
17301840
17462996
17496911
17560373
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19632174
19641494
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21614932
21826665
22955274
23010170
23070005
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
28765050
8910423
8974401
9379049
9488730
9582321
|
TRAF2
|
RIPK1
|
â—¼ SHARES_COMPLEX
|
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
RIPK1
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10465784
11274345
11668179
12048245
12556535
12655147
12738796
14730360
15170913
15592525
17462996
17496911
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23070005
23850759
24378531
26587781
26653790
28574505
28765050
9379049
9582321
|
RIPK1
|
TNF
|
â—¼ SHARES_COMPLEX
|
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
RIPK1
|
TRADD
|
â—¼ SHARES_COMPLEX
|
|
|
78.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11668179
11875494
12048245
12556535
12646658
12655147
12738796
12811837
12887920
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
16713974
17301840
17462996
17496911
17560373
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19632174
19641494
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21614932
21826665
22955274
23010170
23070005
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
28765050
8910423
8974401
9379049
9488730
9582321
|
TRAF2
|
RIPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
92.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11668179
11875494
12048245
12215447
12556535
12646658
12655147
12702723
12724420
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17496911
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21614932
21826665
22427918
22955274
23010170
23069999
23070005
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
28765050
8910423
8974401
9379049
9488730
9582321
9759866
|
RIPK1
|
TRADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
78.0
|
1.0
|
ACSN
|
10465784
10734135
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11668179
11875494
12048245
12556535
12646658
12655147
12738796
12811837
12887920
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15310755
15592525
15699106
16713974
17301840
17462996
17496911
17560373
17916596
18264787
18292600
18633355
18641653
18855897
19392652
19411070
19524513
19632174
19641494
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21614932
21826665
22955274
23010170
23070005
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
28765050
8910423
8974401
9379049
9488730
9582321
|
TRAF2
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
8702708
8612133
25416956
16713569
18621737
25882049
16291755
18981220
21741934
21232017
20577214
11181075
10795740
23972990
21119000
15175328
20203691
21810480
21282461
9712898
32296183
23007157
25716317
20448643
12887920
24735611
15258597
24434549
19815541
16603398
11479302
9020361
|
TRADD
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
12887920
24735611
20203691
21724995
8612133
21741934
16603398
21119000
|
TNFRSF1A
|
RIPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
25681446
11002422
20547836
8612133
18450452
27552911
26802121
10356400
19773432
18621737
23815148
16611992
22179575
12721308
21741934
7538908
18949366
21113135
8985253
10744744
10795740
21119000
22733818
10755617
27321185
15115707
24098568
18939944
18329793
20825417
20448643
15357952
21737329
12887920
24130170
15258597
24758719
16115877
19524513
18724939
16968706
22817896
28817177
18022363
19815541
25388546
21331078
22848449
|
TRAF2
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10820262
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12433365
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18345002
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TRAF2
|
TNF
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10820262
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12433365
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18345002
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
TRADD
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TRAF2
|
TNF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10820262
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12433365
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18345002
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
TNF
|
TRADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
12887920
19287455
15485837
32196115
|
TNF
|
TNFRSF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
98.0
|
1.0
|
Omnipath
|
17145710
19084540
8288897
11448951
23746843
22801493
14732063
2848815
9568681
2158863
8182064
9488135
23070005
20080539
11239407
26670046
14743216
21724995
21133840
24070898
25911380
7852363
2170974
17151142
26186194
27560715
25241761
23032187
24726327
20103630
8805640
11502070
19442713
3034874
23955153
18067990
22099304
15485837
22675546
12753742
1310388
12887920
19287455
10634209
2170559
1331108
24980434
22028622
|
TRAF2
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRAF2
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRAF2
|
TNFRSF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TNFRSF1A
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
26212014
8565075
8943045
8612133
16713569
16611992
22179575
11821416
7544915
12721308
21741934
10795740
21119000
19150425
27321185
25241761
15115707
18776134
15743837
15485837
20448643
12887920
24735611
20333651
18022363
19815541
|
TNFRSF1A
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
17145710
8565075
8943045
11934887
8612133
9915703
11684708
8621670
9430227
19641494
27552911
16611992
21760970
11821416
10187805
21724995
12721308
21741934
21232017
10795740
21119000
15310755
11502070
15115707
23955153
18776134
18939944
9916731
9129204
9082980
15485837
15173123
22297296
15357952
24130170
12887920
10634209
24758719
19524513
15465831
7758105
11035039
8791485
15725726
|
TRAF2
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
71.0
|
1.0
|
ACSN
|
10465784
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11668179
11875494
12048245
12556535
12646658
12655147
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15592525
15699106
16713974
17301840
17462996
17496911
17916596
18264787
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21614932
21826665
22955274
23010170
23070005
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
28765050
8910423
9379049
9488730
9582321
|
TRAF2
|
TRADD
|
â—¼ SHARES_COMPLEX
|
|
|
71.0
|
1.0
|
ACSN
|
10465784
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11668179
11875494
12048245
12556535
12646658
12655147
12738796
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15170913
15592525
15699106
16713974
17301840
17462996
17496911
17916596
18264787
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21614932
21826665
22955274
23010170
23070005
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
28765050
8910423
9379049
9488730
9582321
|
TRADD
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
8702708
8565075
14585074
16713569
27383048
18621737
14743216
12796506
21741934
11181075
21119000
10911999
20203691
10892748
23955153
11112773
18439848
32296183
15485837
12887920
12517920
19815541
11479302
9020361
|