TP53
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23940366
9360971
|
TP53
|
BDKRB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15632413
10748162
|
TP53
|
AVP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11382762
16133124
|
TP53
|
BDKRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
EDN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
RELA
|
CCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CYSLTR2
|
GRIK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GLP1R
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18445652
0710402105
|
GAL
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
USF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RELA
|
F2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11463837
19351910
|
RELA
|
CRHR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20233629
|
ESR2
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16549430
17261755
|
NFKB1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18031796
|
CUX1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14612449
22422878
|
NFKB1
|
ADORA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9547356
|
NFKB1
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21334436
|
CALCA
|
CALCR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
6148938
1331173
|
GRIA3
|
GRIA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0708699104
17989220
|
GNAQ
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219925
17498700
|
GNA11
|
GNAQ
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
ADRA1B
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9481484
31160049
|
ADRA1A
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
1334487
|
GRPR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
17251915
|
GALR2
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
9685625
|
CRHR1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10598591
22869609
|
CHRM3
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
7629074
|
EDNRA
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15475516
31160049
|
HTR6
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12650852
31160049
|
HTR2B
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11916537
31160049
|
HTR2C
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11916537
31160049
|
CCKAR
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
31160049
11313903
|
F2RL1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9349532
31160049
|
EDNRA
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19202075
0807158106
|
ADRB2
|
ARRB2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
EDNRA
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19202075
0807158106
|
ARRB1
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219925
17498700
|
ARRB1
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11579203
17498700
|
ARRB1
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16407241
11171997
|
HTR2B
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11916537
8621713
|
CHRM1
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14976183
12200418
|
CNR1
|
HCRTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29751001
12690115
|
USF1
|
FSHB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19423764
18550775
|
USF1
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1427648
2659342
|
TTF1
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12730191
18395010
|
STAT5B
|
ESR2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11731618
|
ADRB2
|
KCNJ6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ADRB2
|
CCKBR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
HTR4
|
ADRB2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
5217738
15896782
|
BDKRB1
|
GRIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GCG
|
GIPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0706404104
17715056
|
DRD4
|
ADRA1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22723743
1001347
|
DRD4
|
ADRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22723743
1001347
|
DRD4
|
ADRA1B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
22723743
1001347
|
DRD4
|
ADRB1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
22723743
1001347
|
GABBR2
|
GABBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218685
16724110
|
BDKRB1
|
GABBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
BDKRB2
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
TFAP2B
|
DRD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10640692
|
GPR35
|
CRHR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GHSR
|
GHRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10604470
11322507
|
F2RL2
|
F2R
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
17376866
0700763104
|
CTSG
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10978167
|
TTF1
|
GNRH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11036938
11161473
|
IRF2BPL
|
GNRH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17627301
|
CTSG
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10978167
|
APLNR
|
APLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8294032
9792798
|
AGT
|
AGTR2
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
16597412
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GRIA2
|
GRIA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
14687553
17989220
|
CASZ1
|
ESR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29509190
25640309
|
GRIA3
|
GLRB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EDNRB
|
EDN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16713569
12972292
23597562
|
GRIA3
|
GRIA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
KCNJ3
|
KCNJ6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
KCNJ3
|
KCNJ9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
GRIA1
|
GRIK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8288598
10358037
|
GNA11
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
10789830
|
GABRA1
|
GABRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
GCG
|
GCGR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
AGTR1
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11579203
17498700
15611106
|
GRIK5
|
GRIK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8288598
15583001
9466455
|
EDN1
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
16189514
10770212
16713569
7509919
23597562
|
GAL
|
GALR2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
10601261
|
AGT
|
AGTR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CGA
|
FSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
AKT2
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
12149249
9736715
12176337
11445557
33961781
14500673
11278835
11546794
|
AKT1
|
ARNT
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15833858
28628118
28205554
|
ITPR1
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24947355
18250332
|
ARRB2
|
DRD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
32450252
21256133
25162404
|
FSHR
|
FSHB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22802634
15662415
10395410
|
CALCA
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ADRB1
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10862778
18787115
|
ESR2
|
MED23
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
29509190
21182203
11867769
|
HCN1
|
HCN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12928435
11133998
12034718
|
ADRB2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
GABRA1
|
GABRB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
GAL
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
GABRA1
|
GABRG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
TP53
|
EDN2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18431400
|
GIP
|
GIPR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15655707
17715056
12627975
8795084
7589426
|
CTSG
|
C3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24315997
1861080
|
RELA
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10628750
8833654
8613256
|
NFKB1
|
KCNN4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
21725609
23178297
23572150
|
NFKB1
|
AGT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10628750
8613256
|
IAPP
|
CALCR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1331173
9620797
2608057
|
AGTR1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17498700
31160049
11313903
|
GRM1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
1847995
1320017
12351712
|
HTR2A
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11916537
31160049
6483122
|
ADRB2
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23208550
24658140
17148612
24561123
27226565
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
EDNRA
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
7882989
10789830
|
ESR2
|
ADORA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19376833
|
AGT
|
CTSG
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
6807977
9570564
20889553
|
CTSG
|
AGT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11747312
10899625
|
ESR2
|
NR5A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19376833
|
AHR
|
GHRHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14678789
10561076
18086832
|
F2RL2
|
F2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
F2
|
F2RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
873923
8615752
10079109
|
F2RL2
|
F2
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9618465
9087410
1672265
|
F2
|
F2RL3
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9618465
9087410
1672265
|
GLP2R
|
GCG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9990065
10322410
15471943
|
HCRT
|
HCRTR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10583376
9491897
10364220
|
HCRT
|
HCRTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9491897
10364220
16429482
|
GNRH1
|
GNRHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1333190
6090951
9419371
|
GNRH2
|
GNRHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1333190
6090951
9419371
|
CCK
|
UBQLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
AKT1
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
18191226
19122674
19262695
|
GRIA1
|
GRIA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
14602821
24706758
18311135
10358037
|
ADM
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
GIP
|
GIPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
F2
|
F2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
GRIK2
|
GRIK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
ARRB2
|
AGTR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
11226259
11279203
15611106
28298427
|
FSHB
|
FSHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
F2
|
F2RL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
F2
|
F2RL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
GRIA2
|
GRIA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
GH1
|
GHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CGA
|
FSHB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
AHR
|
ARNT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
KCNJ3
|
KCNJ5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
GRIA1
|
GRIA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
ARNT
|
AHR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8065341
28514442
11768231
9704006
11259609
7488247
19380484
20006590
22138065
11025203
10617682
23477502
9887096
31675361
12024042
12139968
11551916
17392787
18096572
8384309
10619402
7628454
19390533
26350169
8631989
8621524
10671489
33961781
10395741
8619634
|
GABBR1
|
GABBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
GRIN1
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
GRIN1
|
GRIN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
YY1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10787423
10634504
8816507
10505791
18391986
|
AHR
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17070097
15111621
11191113
20478272
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
NFKB1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10348347
11032029
8051093
12145335
20097177
|
TP53
|
GHRHR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10529175
24297337
11852084
24737129
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
NFKB1
|
YY1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17438126
21725609
23178297
23572150
|
ESR2
|
CRH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18597742
8408641
17947358
12161509
15564578
|
CRH
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8536644
8243338
23504413
11123370
|
CRH
|
CRHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
8612563
8536644
19124613
7477349
11416224
9178757
7692441
9851694
20966082
11123370
9326293
10598591
18801728
|
CCK
|
CCKAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
10368033
9006937
10595537
11300760
10400673
9603948
|
CCK
|
CCKBR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
10368033
12695525
10438490
8349705
15001692
15520004
7681836
23597562
15068617
|
GIP
|
GIPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
12627975
26572091
17715056
8795084
15655707
7589426
15655705
|
GNA11
|
CYSLTR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10191087
3086311
16754659
1905813
8664309
|
GNAQ
|
CYSLTR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10191087
3086311
16754659
1905813
8664309
|
GCG
|
GLP1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
18248821
11116211
15528268
7937318
8404634
|
GALR3
|
GAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
9832121
9722565
1710578
1722333
7524088
9685625
|
GALR2
|
GAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
9832121
9722565
1710578
1722333
7524088
9685625
|
GAL
|
GALR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
9832121
9722565
1710578
1722333
7524088
9685625
|
GAL
|
GALR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
9832121
11600206
9880084
9480833
10601261
9685625
|
GAL
|
GALR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
9808667
11481429
10689365
11600206
9168941
7524088
9880084
9685625
8617199
|
GAL
|
GALR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
9832121
9880084
9722565
|
C3
|
C3AR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8702752
11342658
8765043
20527893
9476119
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RELA
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20186924
18031796
20649564
|
RELA
|
EDN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21334436
10969841
18226221
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
AKT1
|
ITPR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24947355
18250332
16332683
18955969
|
AKT1
|
AKT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11546794
14500673
12176337
11445557
9736715
12149249
11278835
|
AKT1
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11809767
9032240
|
GCG
|
GCGR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
22863277
4305077
8382034
12529935
|
CALCB
|
CALCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
2177866
8626685
2985435
6609312
14722252
|
CALCRL
|
ADM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
8387282
11693189
10217420
9620797
14615490
|
CALCA
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17145710
11693189
8626685
3001670
16293613
12234182
14668209
23597562
10347248
9620797
|
ADM2
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
21658025
14615490
|
ADM
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11693189
10347248
9620797
|
CALCB
|
CALCRL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11693189
8626685
3001670
12196113
12234182
14668209
10347248
9620797
|
ADCYAP1
|
ADCYAP1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
8703026
16930633
12488235
10583729
11931347
21350482
10100920
17470806
8253796
|
ADM
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
10781016
12565884
15692146
|
CALCA
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
14722252
9487987
7588285
11033437
2158663
1331173
11023820
26125036
10342886
6148938
15692146
12565884
|
ADM2
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21658025
15692146
|
CALCB
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
14722252
9487987
7588285
11033437
2158663
11023820
10342886
15692146
12565884
|
IAPP
|
CALCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9487987
24169554
10342886
12529937
|
GNAQ
|
CYSLTR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10191087
3086311
16754659
1905813
8664309
|
CHRM1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3110621
1341877
8576109
31160049
|
BDKRB1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12130679
11379050
31160049
11713280
|
CUX1
|
STAT5B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
21330321
14660670
17698633
10935490
|
ARRB2
|
ADRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
23208550
17148612
17666399
24658140
27226565
2163110
24561123
22364396
|
GNA11
|
CYSLTR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
10191087
3086311
16754659
1905813
8664309
|
GNRHR
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10734055
1333052
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
AGT
|
AGTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
2775266
21464395
8315512
21542804
17138938
8185599
15930094
9797979
8242249
7850406
|
AHR
|
GCG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16988001
18854429
11845228
7776982
1986932
|
ARNT
|
AHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
17145710
8621524
8384309
9887096
20006590
10395741
18096572
12024042
7628454
9704006
19380484
17823304
11259609
19390533
22138065
8631989
8619634
8065341
11768231
7488247
|
ARNT
|
EDN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7539918
1823643
16716598
12829734
9159130
13130303
9588211
12080085
11566883
10403805
9746763
8943284
15451019
9278421
16887934
|
F2
|
F2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
9058715
10978167
15707890
10644723
14652070
11356985
23450633
18250335
12563219
22972936
|
F2
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10978167
1135698510978160
11356985
|
F2
|
F2RL3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1273221212732210
12732212
22318735
|
F2
|
F2RL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11356985
12732212
1135698512732210
|
GRIN2B
|
GRIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12191494
19487695
15030493
8139656
|
GCG
|
GLP2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
24990862
11738243
9990065
|
FSHB
|
FSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15662415
17145710
2126341
10395410
|
CGA
|
FSHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15662415
2126341
12374801
30910395
|
C5
|
C5AR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
9881961
11773063
9553099
15661745
10602324
1847994
|
GH2
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
2387255
1955498
|
GH1
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
2825030
8943276
17500058
1549776
9353194
26713839
1935820
31279174
9030599
23331499
7862673
7691587
19927328
10551877
21889455
9571026
3349036
2387255
31100495
29145629
24280222
24243840
|
HCRT
|
HCRTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
85.0
|
1.0
|
Omnipath
|
18488139
11250867
14691055
11266181
17115071
11162621
9491897
21718304
26582739
12702704
12606634
21362456
15271651
11403934
22550093
10498827
11205421
20002100
18599270
12208495
|
HCRT
|
HCRTR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
9491897
26582739
12702704
12606634
10498827
27237973
12890892
18599270
11162621
12208495
|
STAT5B
|
GH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20378540
12127257
11517160
12682066
16339156
12588773
20702579
14532269
9231797
11562369
10373481
15677453
|
EDN1
|
EDNRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
EDN2
|
EDNRB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
EDN1
|
EDNRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12972292
16597412
16713569
15629009
8440682
|
EDN3
|
EDNRB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
8460684
8086489
8904635
11982704
8001160
15629009
8440682
7524189
|
EDN1
|
EDNRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
90829707
6479761
9082970
7509919
16597412
16713569
23597562
15629009
8440682
7647976
10770212
|
GALP
|
GALR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10689365
1068936515944000
15944009
23233848
|
EDN3
|
EDNRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
EDN2
|
EDNRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
1710450
1719979
8440682
2649896
|
EDN2
|
EDNRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
2175397
9082970
15629009
8440682
7647976
|
GRP
|
GRPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
17251915
1720612
10454496
7838118
19463875
21729729
|
GNRH2
|
GNRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17942747
17452338
19638591
|
GNRH1
|
GNRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
26398856
414473
11726197
17452338
9414473
19640273
26774084
4930860
17095587
|
CORT
|
GHSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12161511
1122773711227730
11227737
|
AVP
|
AVPR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2991279
4065330
8106369
7929452
|
AVP
|
AVPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
2991279
4065330
8106369
7929452
|
AVP
|
AVPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
15084136
9334232
10519430
12446593
10780976
9884074
1560825
9322919
9264324
9459574
9864265
8106369
10866830
|
AVP
|
AVPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
73.0
|
1.0
|
Omnipath
|
15084136
10519430
12446593
10780976
9884074
1560825
9322919
11012895
9264324
7774575
11857925
9459574
9864265
|
AVP
|
AVPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
15084136
10519430
12446593
10780976
9884074
9322919
9264324
9459574
16158071
7929452
9864265
|
GHRL
|
GHSR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
29233536
12907757
21402696
11314756
11227737
10628755
10604470
15905359
15070777
|
KISS1
|
KISS1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
15665093
11457843
11385580
12944565
|
GHRH
|
GHRHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
1333056
26917260
7680413
76804131333056
|
APLN
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
10617103
12939143
11336787
10802050
10777510
12603839
16189514
9792798
15341513
|
GRP
|
BRS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11112777
|
APELA
|
APLNR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
29357134
25995451
25639753
29079036
28137936
26611206
28663440
24316148
|
GALP
|
GALR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9832121
983212115944009
15944009
|
GALP
|
GALR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9832121
20880399
10601261
15944009
23233848
|