Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
E2F6 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15574595 18319725
SMARCA4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7914327 20224553
HIST2H3A HIST2H3D â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RRP8 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H3C2 L3MBTL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16415788 5218238
H3C2 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H3C2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
PTEN CSNK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
CSNK2B SET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23374587
EPAS1 KDM5C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
KDM5C FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23872847 23545502
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
LHX6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KDM5C ME3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17320160 23545502
KDM5C KRT9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17320160 17468742
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
SMARCC2 PEX14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCA4 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
PKCB1 MGAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 31753913
TFDP1 MGAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
RING1 MGAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
K1683 KDM5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PKCB1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 31753913
PKCB1 MBD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 31753913
KDM5C PKCB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 31753913
TRI35 KDM5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEFI8 KDM5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NOE2 KDM5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CBX3 TFDP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
REST EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17468742 15200951
HDAC1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26496610
SSH3 KDM5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SKP2 KDM5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TFDP1 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
HLAF KDM5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC1 MGAP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
RHG25 KDM5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC1 PKCB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31753913 26655721 26496610 23752268
BRD4 CBX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34079125 30554943 32416067 31239290
MAX CBX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 29028833 27705803
MAX E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 25609649 27705803 29028833
HDAC1 E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
IER2 KDM5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LHX6 KDM5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SCML4 KDM5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAX RING1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 29028833 27705803
CBX3 HIST2H3D â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 HIST2H3A â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HIST2H3D PHF8 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST2H3A PHF8 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST2H3D PBRM1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HIST2H3A PBRM1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
HDAC2 HIF1A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25241761 11641274
MAX TFDP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24981860 25609649 27705803 29028833
KDM5C THTPA â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
EP400 MAX â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
KDM5C MGAP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 17468742
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
MGAP MAX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 20936779 25609649 21988832 27705803
E2F6 MGAP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26186194 27705803 28514442
BRD4 H32 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31239290 18500820
BAP1 CBX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 29686263 32509391 34591877
CBX3 RING1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 12004135 27705803
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
HDAC1 REST â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10491605 18806873
HDAC1 TFDP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27705803
SMAD3 MAX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25241761 16189514 12551947
EHMT2 HIST2H3D â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
KDM5C H32 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17320161 17468742 17320160
KDM5C E2F6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 17468742
E2F6 RNF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
KDM5C MAX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 17468742
E2F6 MGA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC2 SMARCA4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MGAP CBX3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 34079125 20936779 27705803 20850016
CBX3 E2F6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 12004135 27705803 34079125
MAX EP400 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 11509179 25609649 20946988 29028833
HDAC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14988403 11929879 16189514 16713569
TFDP1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7734951 14618416
CBX3 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19111658 16127177 17540172
PHF8 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20531378 20210320
KDM5D H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
KDM5C H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
EHMT2 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 17962312 22514736 15200951 27705803 34079125
MBD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 33961781 10471499 12183469 12665568 27173435 24981860 21258344 17634443 26496610 11102443 23752268 28514442 11297506 27593931
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
HIF1A KDM5C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020 32938217
MBD2 ME3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23970103 20714105 20644511
E2F6 TFDP1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
TFDP1 E2F6 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CBX3 EHMT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
E2F6 RING1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11171983 24981860 27705803
HDAC2 MBD2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
PBRM1 SMARCA4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PBRM1 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SMARCA4 SMARCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
REST BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 21832040 11779185 18518926 23145961 17041593 23151521 18075316 20126541
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
MBD2 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22152480 22371483 20650264 20644511 23970103 20714105 25254151 20851996 23711388
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
SMAD3 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 25241761 16189514 12551947
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
NCOR1 SMAD3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10549282 10485843 10535941 10531062 11389444
REST SYN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15654842 20530487 18692536 23250796 9756936 12492469 11741002 21693630 9820593