IL1B
|
CASP1
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0812690106
19439663
|
EXOC4
|
EXOC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
23037926
|
IL1R2
|
IL1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16971486
0603545103
|
IL1A
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16971486
0603545103
|
IL1RN
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1828071
2139180
|
EXOC1
|
EXOC5
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
EXOC4
|
EXOC5
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
EXOC1
|
EXOC8
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
EXOC7
|
EXOC8
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
EXOC1
|
EXOC3
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
IL1R2
|
RSPRY
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
NDUAC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
NDUS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
DYN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
CCD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
ZNT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
EXC6B
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
27173435
|
EXC6B
|
EXOC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
27173435
|
IL1R2
|
EXC6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
AT2B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
RHBT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
CIP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
DUSTY
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
SE6L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
MTU1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
NUD16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
CBWD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
CISD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
EXOC1
|
JUN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
NLRX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
SCRIB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
QSOX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
LONP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
TBCD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
OCRL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
IL1R2
|
LRRC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
EXOC4
|
EXOC8
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
EXOC3
|
EXOC4
|
â—¼ CORRELATES
|
|
+
|
0.82
|
0.82
|
CCLE
|
31978347
|
EXOC3
|
EXC6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
27173435
|
EXOC2
|
EXOC5
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
EXOC2
|
EXOC3
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
IL1B
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
EXOC5
|
EXOC8
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
EXOC2
|
EXOC8
|
â—¼ CORRELATES
|
|
+
|
0.84
|
0.84
|
CCLE
|
31978347
|
EXOC1
|
EXOC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
NDUAC
|
NDUS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24344204
22939629
33961781
|
EXOC1
|
EXC6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
27173435
|
EXOC7
|
EXC6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
27173435
26344197
|
EXOC8
|
EXOC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
27173435
|
EXOC6
|
EXOC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
27173435
|
EXOC1
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
27173435
|
EXOC1
|
EXOC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
27173435
|
EXOC1
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
IL1AP
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9862719
20802483
|
EXOC7
|
EXOC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14525976
27173435
22939629
26344197
|
EXOC5
|
EXOC7
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
EXOC2
|
EXOC4
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
EXC6B
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
27173435
26344197
|
EXOC1
|
EXOC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
EXOC8
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
27173435
26344197
22939629
28514442
21241894
|
EXOC7
|
EXOC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
27173435
26344197
|
EXOC1
|
EXOC4
|
â—¼ CORRELATES
|
|
+
|
0.89
|
0.89
|
CCLE
|
31978347
|
IL1AP
|
IL1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9820540
22426547
16306937
20802483
|
CASP1
|
IL1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18329368
|
EXOC4
|
EXOC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
27173435
26344197
17043677
31413325
90000000
19889837
28514442
19885391
|
EXOC7
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27173435
26344197
12687004
22939629
12738960
21241894
|
EXOC1
|
EXOC2
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
IL1R2
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
EXOC5
|
EXC6B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
27173435
32296183
26344197
|
EXOC4
|
EXOC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
27173435
22939629
21241894
26344197
|
EXOC6
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
EXOC4
|
EXOC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
EXOC6
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
EXOC3
|
EXOC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
EXOC5
|
EXOC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
IL1B
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
EXOC2
|
EXOC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
EXOC5
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
EXOC7
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
EXOC2
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
EXOC3
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
EXOC2
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
EXOC2
|
EXOC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
EXOC3
|
EXOC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
EXOC4
|
EXOC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
EXOC5
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
EXOC2
|
EXOC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
EXOC3
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
EXOC4
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
EXOC4
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
EXOC2
|
EXOC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
EXOC3
|
EXOC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
NDUFA12
|
NDUFS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CASP1
|
IL1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
1919001
7642516
7797510
17039247
28147281
8999548
19439663
9121587
|
JUN
|
CCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19162185
18024959
18443042
14752027
22674286
23583295
19299558
12667961
10918580
19371341
26554515
|
JUN
|
GLI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11001584
11274345
16054035
16396903
16406505
16880536
17000779
17439715
17638910
18754008
18813803
19081070
19190345
19219074
20107231
22354771
23031257
26587781
8545107
|
JUN
|
GLI1
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11001584
11274345
16054035
16396903
16406505
16880536
17000779
17439715
17638910
18754008
18813803
19081070
19190345
19219074
20107231
22354771
23031257
26587781
8545107
|
JUN
|
GLI1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
11001584
11274345
16054035
16396903
16406505
16880536
17000779
17439715
17638910
18754008
18813803
19081070
19190345
19219074
20107231
22354771
23031257
26587781
8545107
|
GLI1
|
IL1R2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
11001584
11960000
12138125
14555646
15087129
15520176
16054035
16158046
16328026
16396903
16406505
16571352
16880536
17000779
17035233
17638910
18754008
18813803
19081070
19190345
19219074
19736394
20107231
21059263
21442356
22354771
23031257
|
JUN
|
IL1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19299558
8688489
|
IL1A
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9820540
9862719
7775431
17507369
|
IL1A
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
25241761
16971486
7878046
1833184
9862719
23395675
78780467878046
|
JUN
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11306276
18566416
7935377
10226077
14686613
16365456
11145674
17283046
20463008
23608488
8133045
8798756
18789903
16729332
|
IL1B
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
8332913
7878046
1833184
20802483
|
IL1B
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9820540
7775431
20802483
|
JUN
|
IL1R2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11274345
16054035
16396903
16406505
16880536
17000779
17439715
18813803
19190345
19219074
20107231
26587781
8545107
|
IL1RN
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20959797
24332029
1834644
7878046
1833184
|
NDUFS4
|
NDUFA12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFS4
|
NDUFA12
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|