Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IRF3 TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
IRF3 TBK1 â—¼   COLOCALIZATION 2.0 0.8 intact 17599067 5220070
CDC37 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DDX3X TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
MAVS IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
TRAF2 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
TRAF3 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
HSP7C MAVS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IKKE PSB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30682859 17353931
IKKE PSDE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32476569 17353931
IKKE IRF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079066 19153231
HS90A TPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 16263121
MAVS CYLD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30410068 18636086
CYLD DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27591049 31762063
TM173 IRF3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33086059 25636800 24622840 30018345
IKKE HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939624 14743216
TM173 IKKE â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28346439 22312431 19433799
IKKE TRAF3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32656094 24763515 34084167 29920243 23308279 26519536 29125880 27980081 19380580 22079989
TBK1 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939624 14743216
TRAF2 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25241761 14743216
MYL6 MYH10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
IRF3 HS90A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20628368 16394098
CLH1 HSP7C â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 27684187
MAVS IKKE â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24706939 21903422 32511263 16177806 19380491 21200404 19153231 29125880
IKKE TCPE â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25852190 14743216
IKKE HSP7C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
HS90A IKKE â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939624 14743216
IKKE ML12A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
IKKE RUVB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
TPM3 IKKE â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
IKKE MYL6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
IKKE CALM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
IKKE TBKB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17568778 21931555 21903422
TBK1 TM173 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22745133 33086059 32383759 23542348 21903422 29899553 30943264 24622840 28763789 19433799 31534043 18724357 33139700 33767426 21074459 28346439 32678307 19416887
MAVS DDX3X â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20127681 27980081
TANK TRAF3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAVS TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IRF3 MAVS â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IRF7 IRF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11162841 18641315
IKKE CLH1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14743216 17353931
RUVB1 HSP7C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17643375 27684187
TBK1 IKKE â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29251827 21903422 30420664 31534043 32298923 25939384 17599067
IKKE CYLD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18636086 23453969 29755980
IKKE MYH10 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14743216 17353931
DDX3X IKKE â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20657822 18636090 27980081
HS90A TBK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22939624 20628368 14743216 16394098
MAVS TM173 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23542348 20080758 24622840 18724357 22908223 22000020 22312431 19416887 22911572
TBK1 CYLD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18636086 25923723 29755980
TBK1 MAVS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33372174 24643253 21903422 32511263 21813773 25636800 23028469 29125880 28346439 32366851 29743353 16153868
MAVS TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HS90B HSP7C â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29930177 25864199 26344197
IKKE TRAF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 23453969 23007157 25852190 14743216 20449947 29125880
TRAF3 TBK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22792062 32779804 20174559 22908223 19380580 33187908 24763515 24622840 27135603 23308279 29125880 22079989 33411856 33372174 34084167 32324863 33608556 31404116 23717208 23986588 28049150 26928339 29920243 17991829 22330071
TANK TRAF2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
IRF3 IKKE â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32656094 27622505 22072751 28346439 15695821 19153231 19380580 18636086 12692549
IRF3 TBK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843640 20304918 18636086
IRF3 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20483755 15367631 15664995
HSP7C HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20039095 26344197 22504172 27708256 25864199 19875381 9269769 16189514 21360678
IKKE CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 21903422 14743216 17353931
IKKE TANK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 23007157 10759890 25852190 21931555 21212807 17823124 17568778
MAVS IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950 16153868
MAVS TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
IRF3 TBK1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
TBK1 IRF3 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17599067 5220070
TBK1 IRF3 â—¼   PHOSPHORYLATION ✅ 0.92 0.92 mint 6948053 18583960
TBK1 IRF3 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 17599067 5220070
PSB1 PSDE â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 27428775 17323924 22939629 28821611
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
TBK1 TRAF3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 22792062 26221961 23545497 22908223 19893624 20080758 30527812 24622840 29125880 22022264 22079989 31390091 33411856 16858409 30267576 22901541 21200404 32324863 33608556 19419966 32511263 31806368 26519536 27980081 32366851 33582548 27348524
TANK TBK1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC37 HS90A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21871133 25036637 33961781 27353360 22729780 26496610 19875381 12930845 9685350 15647277 16335536 25486457 24462205 22504172 22939624 22315411 12176997 20159553 24292678 24189400 21360678 26804907 15001580 11413142 21745565 14718169 16611982
CDC37 HS90B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28215707 25036637 33961781 26496610 11036079 22939624 23428871 27339980 24189400 25486457
TBK1 TBKB1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 27035970 21903422 30420664 29395067 14743216 21931555 23286385 17568778 32707033
TBK1 TANK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 31114588 30420664 23286385 18307994 23007157 21931555 17568778 32707033 30561431 10581243 29395067 14743216 21988832 17823124 25409927 24488098 16189514 29251827 27035970 21903422
HS90A HS90B â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 31536960 25036637 33961781 26344197 26496610 20353823 19875381 22863883 21360678
TRAF3 IRF3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
TBK1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 24549848 18583960 22072751 16380379 26811330 16127453 17618271 23478265 19153231 12692549 28618271 17599067 22388039 15841462 25636800 21903422 15210742 33990776 20532218 16699525 20170763 30842273 12702806 16306043 17018283 20628368 16914100 33411856 23746807 28159912 16394098 18356163 22904301 34379517 22810896 14703513 22750291 27548204 29800227 22079989 24056301 14679297 17706453 20511230 24396068 19211767 18440553 16281057 12524442 16625202 9463386 19893624 18636086 15749911 18818105 27125670 24807708 15695821 9566918 30496178 17526488 19656901 23028469 32351706 24371060 15367631 16199137 25803835 24622840 16155125
MAVS IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17020950 25636800 21903422 16153868 22750291
CYLD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12917691 23405219 17851586
TANK IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
TRAF3 IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
TBK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 17599067 9786932 15210742 22787218 26712804 16127453 12702806 15367631 12692549 16380379 17706453 16199137 16914100
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
MAVS TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 21813773 15210743 16127453 33372174 17020950 25636800 21903422 15210742 16753195 16306936 12702806 24643253 16177806 27419230 16153868 16858409 29743353 17468758 17327220
MYH10 MYL6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
TANK TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16127453 17568778 27035970 25409927 23286385 18307994 24488098 21419663 21988832 21903422 15210742 14743216 16189514 19820708 21931555 10581243 23007157 17823124 17468758 17327220
TANK TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20562859 21988832 21903422 8710854 12005438 14743216 10581243 16713569 23007157 10759890
TRAF3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27135603 15210743 16127453 15210742 16306936 12702806 23986588 22792062 16177806 20389019 17991829 20174559 16858409 23717208 34084167 22330071 17468758 17327220 24622840