ATM
|
H2AX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1106300109
22451927
|
FOXO3
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18344987
18424439
|
E2F3
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18469863
12527885
|
ATM
|
H2AX
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16858402
5218840
|
E2F3
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12527885
18319725
|
CASP3
|
BID
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
FAS
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15659383
25241761
|
CTSS
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14581476
|
CTSK
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14581476
|
BID
|
CYCS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9873064
9727491
|
CAPN2
|
CASP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CASP8
|
CASP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18669646
0712034105
|
FOXO3
|
CASP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20211690
19807657
|
CASP6
|
CASP3
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP3
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17899380
|
CASP3
|
EIF4EBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10672017
|
CDKN2A
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
CTBP2
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19798104
23255392
|
ETS1
|
COL1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16564026
|
DNAJB1
|
DNAJC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16189514
9920933
|
FOXO3
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12391153
15509806
|
ATF4
|
CASP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CEBPB
|
GADD45G
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11012671
|
BCAR1
|
ACTB
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6174726
18164686
|
IRF5
|
CCL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20483755
12138184
|
FYN
|
CYCS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATP6V1G1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PSME2
|
PSME1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
FCGR2B
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
CNTFR
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
CD28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
FYN
|
CSF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8981370
20489731
|
FYN
|
CD86
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8946678
9973466
|
FYN
|
FAS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17159908
5219434
|
IFNGR1
|
IFNG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
376230
7617032
|
IFNGR1
|
CAMK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
IFNG
|
CAMK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
FGB
|
BCAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16581250
8649368
|
FZD5
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10428961
8666229
|
AXIN1
|
CSNK1A1L
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11884395
23331499
|
ETS1
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11970950
|
CEBPB
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7543095
11473033
|
BIRC2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17145710
12887920
|
CEBPB
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7513199
21455770
|
ETS1
|
CD3D
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12324448
|
IFNGR2
|
CAMK2B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15322115
11972023
|
ATF6
|
DNAJC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12601012
|
CEBPB
|
APOBEC3G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18809921
0807269105
|
GNB3
|
GNA11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
GNA11
|
GNB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
CASP6
|
GNB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GNA11
|
GNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
25675501
15889144
|
CHRM2
|
GNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8786435
3037705
|
CHRM1
|
GNB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14976183
8196770
|
F2RL3
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17158345
31160049
|
GNAI1
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15922020
19703466
|
CYP2C8
|
APOE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21163940
114280
|
ERBB2
|
BLNK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
IFIT3
|
IFIT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CHRM1
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14976183
12200418
|
CD3D
|
CD3E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3D
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
CD3E
|
HLA-DPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
ATP6V1G2
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14667819
5216829
|
BMPR1B
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1A
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10712517
|
ACVR2B
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
CASP1
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667412
|
CASP6
|
CASP7
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
intact
|
0707715105
18723680
|
CASP12
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209154
|
CFD
|
CFB
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
809512
279011
|
BMP6
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
CNTFR
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21715184
10966616
|
BCAP31
|
FDPS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
CLEC4E
|
CXCL9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
BCAR1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
EPHA2
|
EFNA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
7218654
19525919
|
CCR1
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
IFNA4
|
ISG15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ATF4
|
CEBPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20102225
11018027
|
AXIN1
|
AXIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22682247
20128690
|
CD244
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23346089
15169881
|
DAXX
|
CHMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26496610
|
IFNA4
|
IFNA8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CXCR2
|
GNAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
IFNA8
|
ISG15
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BIRC2
|
BCL10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16775419
33961781
10753917
|
DAPK3
|
DAXX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12917339
|
CD27
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CD27
|
ADCY9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFNA8
|
IFIT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
GNA11
|
EDNRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
10789830
|
IFNA8
|
IFIT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFNA8
|
OMA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
ERBB2
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30898150
28628118
28205554
|
ATF4
|
DAPK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9488481
21408167
|
CCNE1
|
CDK6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9716181
28628118
28205554
|
CD244
|
CD48
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
CD86
|
CD28
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27708164
21931534
11021528
7513726
|
CCL23
|
CCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886417
9558365
10660125
|
AXIN1
|
CSNK1A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
BIRC2
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
ATM
|
H2AX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16858402
27918549
22184063
9488723
32518374
20081839
18344987
21676867
22451927
21704408
11571274
11893489
26095369
|
CASP8
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9727492
15659383
9727491
12097160
11832478
12196516
11085743
|
CASP3
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
10364179
11399776
18723680
|
CCNA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25091198
16713569
9244350
10373534
|
CASP8
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
15254227
11832478
18669646
11437602
8962078
|
CASP6
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8900201
25241761
18723680
|
CASP8
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12887920
27810922
15069192
22274400
|
BIRC7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
25416956
33961781
26186194
22711539
21113135
|
GSTM5
|
GSTM4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
26186194
|
DNAJB1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PSME1
|
PSME2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
GSTM4
|
GSTM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ATM
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
IFIT1B
|
IFIT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HuRI
|
32296183
|
DNAJC3
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CD3D
|
CD3E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CCNB1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
11278247
23246971
9244350
|
BIRC2
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
17069460
9384571
11084335
19258326
11106668
|
BIRC7
|
CASP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11024045
23563149
11084335
|
CUL4A
|
CUL4B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17041588
31973889
23555860
18593899
33961781
16964240
21145461
30945288
32140073
|
EFNA1
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14692877
7973638
8755474
19573808
20505120
8139691
22244754
19525919
|
ATP6V1E2
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
DAXX
|
ETS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15247905
16861237
10698492
|
CASP7
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
16339151
9384571
11084335
33961781
15580265
19258326
|
IFIT1
|
IFIT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
25416956
21642987
21516116
27107012
30833792
|
CASP8
|
BID
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9727492
|
ATM
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11114888
11278964
29656893
10783165
11016625
10866324
10550055
15713674
18344987
10608806
17478428
|
FOXO3
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18344987
|
H2AX
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12485996
34321665
19766185
18001824
31501894
11927591
18344987
20681793
26095369
18001825
29499138
19805520
26121674
10959836
12419185
|
E2F3
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17106239
|
CASP3
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12149654
|
EGR2
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
PSME3
|
CDKN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18805416
31565481
|
EFNA5
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20228801
20505120
9245480
33961781
|
ETS1
|
COL1A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16564026
24058639
11278621
|
H2AX
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
ATF4
|
CEBPB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16026328
|
ATF4
|
EIF2AK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23009153
21146245
17141186
|
CDK6
|
CCND2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
16713569
28628118
10022865
28205554
11360184
30217970
33961781
23602568
11358847
9178893
|
FYN
|
CLEC4E
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
11110698
17050534
18776906
|
GPSM3
|
GNAI1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
14656218
33961781
25416956
|
PSME2
|
PSME1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32296183
8663520
16189514
9346951
22863883
33961781
19017543
22939629
9325261
|
EIF4E
|
ETS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
15563472
9155017
9878069
|
APC2
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9601641
10980707
|
CSF1
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
ETS1
|
FLT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16861237
18625704
10554042
|
ETS1
|
CSNK2A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10849443
19027835
|
CASP1
|
FGF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18329368
|
IRF5
|
IFNA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18332133
18824541
12138184
|
EDNRA
|
GNA11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
7882989
10789830
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
CLCF1
|
CNTFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26858303
11285233
10966616
11294841
|
ACTB
|
ACTG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
GNAI1
|
GNB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
FAS
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
11717445
5214823
|
CASP8
|
FAS
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
5219431
17159907
|
FAS
|
CASP8
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
16498403
5218359
|
DLG1
|
DLG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
12351654
26496610
|
CASP8
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
GNB5
|
GNG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CCND2
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1C1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
ACTG1
|
ACTB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8153045
21516116
|
ELOC
|
ELOB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
8153045
21516116
|
ATP6V1E1
|
ATP6V1G2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
950.0
|
0.95
|
STRING
|
36370105
|
ATP6V1C1
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
BCAR1
|
FYN
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10739664
32296183
9360983
16713569
17474147
31413325
9188452
|
ELOC
|
ELOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
10205047
25416956
12149480
20211142
23333304
21516116
30166453
23988114
32296183
31253590
19159283
10449727
17922844
10587522
12050673
9447969
17997974
11739384
29401731
24402281
7660129
22939629
21822215
10224134
12004076
22863883
24981860
31444342
16675548
26344197
|
CHMP2A
|
CHMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
IFIT1
|
IFIT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
EFNA1
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
EFNA5
|
EPHA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
ATP6V1E1
|
ATP6V1G1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
EIF4EBP1
|
EIF4E
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16504179
5218377
|
CDK6
|
CDKN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
ATP6V1A
|
ATP6V1E1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
GNB5
|
GNG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB3
|
GNG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB3
|
GNG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB4
|
GNG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB4
|
GNG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
GNB2
|
GNG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
EIF2B4
|
EIF2B5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EIF4E
|
EIF4EBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
H2AX
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11934988
15279782
12792649
11893489
10959836
|
BRCA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
22021381
16153896
18923075
18805091
21325134
22792074
19419957
21052091
18971343
25122754
11301010
21240188
|
ATM
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
18662573
16122425
25077544
16122426
21113148
17525332
|
ATM
|
EIF4EBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
9806882
17525332
10713094
21315178
17570479
26777338
10608806
11146653
12588975
18212344
29152614
|
ATM
|
DAXX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23405218
17525332
25659035
|
ATM
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
197.0
|
1.0
|
Omnipath
|
27410735
28544233
16426903
28797244
9488723
23847653
30197789
21930799
18158901
21693595
18848500
22819196
15603757
16760673
17570479
24688021
24793032
27458206
16531125
22028490
30154456
19230794
23202908
25852739
19059218
26073471
22247744
28259974
29584802
25691887
19049966
20368801
26700820
29386061
28124509
20613862
27550454
20847938
27388041
27752097
23269287
24480460
22237206
20461094
20971043
26941327
18285803
21690091
15279774
23891287
25847270
24490130
25349305
26906421
20637859
26314960
15286739
27780918
20454618
30013081
28671946
25218945
23742011
26391293
23972723
23382699
26416514
27442013
20703100
24726884
26512707
27332952
29641431
25287622
26295265
14643438
29163809
25264544
19895790
26504743
26113859
27431324
28790385
18413980
21283714
21787120
20205745
19781914
25093845
27135971
23227178
22224778
20923785
20860841
24244154
23386996
30065307
16858402
11879731
28009280
23343929
20192759
22761798
26855420
24378750
20068231
20580718
14504478
24893124
29048667
25661368
26860083
26019182
20488183
28764946
22205726
23977391
18471973
19591958
28239143
20542002
17525332
20495376
18755145
23050241
17782711
11571274
19473884
28431265
25742493
18248856
17690115
20684759
26317467
21727091
24651472
25827888
27164092
28587922
20976184
30723510
20471486
23772364
29794999
11893489
19014481
20165693
26671524
16997395
20936109
26114388
23845989
15138496
22761813
23355489
27455285
28943310
21348461
19647519
23678292
23166506
28099474
29434792
25249630
25269479
27310012
15177039
22559321
26045162
20865059
22972376
21148072
26760771
21188122
22962268
22768044
26711340
20460517
27845910
28855246
|
ATM
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
79.0
|
1.0
|
Omnipath
|
26927092
17303408
15159397
24746700
12024016
10866324
30197789
12919958
11114888
26745677
26383678
34301763
12427729
11313470
16163361
28035057
20068231
25939603
26320175
17570479
19683496
22743550
10608806
23802008
23847781
21203981
15964794
12183412
12607003
17525332
19996295
15459660
11278964
19651622
21706030
11877377
20952512
10373534
19622773
10550055
27170701
15212693
23704879
|
CAPN2
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
21887410
23242420
|
CAPN1
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
19931333
|
CSNK1A1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11583622
12598529
20356928
|
CAPN2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18469004
12000759
20709625
17264306
21670566
11404357
21738214
16129881
17593948
21266584
11940658
|
CASP3
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
11085742
11085743
|
CASP8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
12196516
18458084
9727491
11085742
11085743
12097160
9873064
|
CASP1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11085743
9727491
|
CAPN1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18469004
12000759
20709625
17264306
21670566
11404357
21738214
16129881
17593948
16189514
21266584
11940658
|
CSNK2A1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11583622
12598529
20356928
|
BRCA1
|
H2AX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18001824
18001825
17145710
12419185
|
BIRC7
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23563149
11024045
17145710
11084335
|
BIRC2
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
9990849
12042762
9384571
17069460
11382748
11106668
16189514
11084335
|
CASP8
|
CASP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
15755874
17179148
9501089
9950028
18669646
23308069
10988287
18458084
16964285
9885230
9765224
11437602
15014070
21295084
8962078
9208847
|
CASP3
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11511102
11447317
10712510
|
CASP3
|
CASP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
25241761
17899380
8900201
9922454
18723680
|
E2F3
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18663357
15175242
11883935
19340300
|
ELF4
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20814243
21447739
18596985
19233846
|
ETS1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17370299
22714536
11234019
19240179
|
E2F3
|
CDKN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15177020
15175242
18319725
11883935
|
CDKN2A
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
17881001
26186194
23602568
9751050
11739795
11556834
9380698
15232106
16713569
17955473
10491434
16915296
17909018
|
HSPA1A
|
DNAJB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10954706
1754405
1586970
9920933
15802566
12974469
12853476
|
HSPA1B
|
DNAJB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10954706
1754405
1586970
9920933
15802566
12974469
12853476
|
EFNA5
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
20228801
9245480
24003208
15114347
22570727
11114742
9330863
20505120
|
EFNA1
|
EPHA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
8139691
20505120
23331499
11248553
14692877
24003208
7973638
8755474
18988627
15114347
9576626
22244754
9330863
19573808
11114742
19525919
|
CSNK1A1
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20110348
19188143
|
CEBPB
|
GDF15
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24086573
20110283
|
IFNG
|
HMGB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
HMGB1
|
FYN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12646658
15802534
19931333
22842346
26618107
27048821
27192565
|
HMGB1
|
AGER
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20192808
9812979
19727205
25014009
32296583
|
ETS1
|
HMOX1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15590657
20348279
16310515
10022513
|
IRF7
|
IFNA13
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
21670437
10933732
12077266
11473119
17785777
9877175
10938111
19798431
11303025
12242290
16612387
16251417
21940674
15265881
12138184
16175599
19349300
10692430
27012395
11162841
17702615
|
IRF7
|
IFNA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10938111
11884139
9786932
19557165
16014964
16380379
17785777
9877175
24185615
10692430
|
CCND2
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10477583
17517622
16713569
|
CEBPB
|
CCL3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20702408
19109189
24038085
9885903
|
CCL3
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
11170631
10734056
10488147
10699158
7545673
10202040
22633458
10498628
9169459
9336350
10910894
8530354
23765404
9687537
9207005
20219869
9115216
9624164
10660125
7622448
12381680
|
GPSM3
|
GNAI1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
14656218
22843681
32296183
25416956
|
CSNK2A1
|
EIF2B5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11500362
18669648
|
FYN
|
CD28
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
|
FYN
|
CD86
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
FYN
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
16286920
19290918
19909365
20814939
20819927
21378271
22437870
22683124
22863785
24440149
27192565
28900677
9738502
|
FYN
|
FCGR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8756631
17474147
10704309
|
FYN
|
BCAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17129785
9188452
9020138
10739664
31413325
16713569
11181827
9360983
17474147
|
CD48
|
CD244
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
10359122
15998796
16081768
26794910
|
CD48
|
CD244
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26697006
9834056
26794910
16002700
11163399
15870174
18296487
15153464
|
IFNG
|
IFNGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNGR1
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
42.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
22003200
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNGR1
|
IFNGR2
|
â—¼ SHARES_COMPLEX
|
|
|
42.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
22003200
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
16110316
12915721
12438563
7514165
15530433
23331499
16237089
23898330
9111318
15143187
16467876
10986460
18988627
1396683
8550631
20304997
11250200
10860730
12165521
29145629
10811850
7617032
18591661
8631301
7615558
7510216
7673114
|
IFNG
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR2
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
CEBPB
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10995751
15878863
16331681
17556653
19521987
11312260
11009091
8634139
|
IFNG
|
IFNGR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
12915721
7673114
7514165
12438563
15530433
23331499
16237089
9111318
15143187
16467876
10986460
18988627
1396683
8550631
29145629
10811850
7617032
18591661
8631301
7615558
7510216
20304997
|
EIF4E
|
ALYREF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
23582887
17317185
20630994
19494120
|
EIF4EBP1
|
EIF4E
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
111.0
|
1.0
|
Omnipath
|
24211447
24722188
35044719
16824195
18957614
8521827
25416956
11553333
10405182
22509910
11605658
17254965
16271312
17689282
22586265
16648488
16467844
12747827
16242075
10772338
12604610
12867426
12747804
10330171
21798997
12482586
16189514
15550948
21191102
12071973
10406811
18955708
12105188
20224576
17353931
26186194
8816458
17316564
15094042
10753870
16798736
10022874
32296183
19834456
10698949
15153109
15661536
11146653
12588975
16504179
10394359
7935836
7651417
22678294
20880835
10364159
23584478
15767663
|
CSNK1A1
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11487578
11955436
11884395
12554650
8638126
19244247
15327768
10581160
10421629
12051714
17318175
|
DAXX
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9184224
9488730
9759866
|
DAXX
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
40.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9184224
9488730
9759866
|
DAXX
|
FAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
40.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9184224
9488730
9759866
|
CSNK2A1
|
DAXX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21474068
|
FAS
|
DAXX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
15725726
9743501
25241761
11483955
11773067
11003656
14637155
11193028
11495919
9215629
|
BCAP31
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
9334338
17145710
12668660
|
CASP8
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18073771
9545235
10872455
18329793
9727491
9463409
|
CASP8
|
CASP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18329793
12232792
9727491
|
CSF2
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2
|
IRF5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
ETS1
|
CSF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9190901
7478534
8611694
15907486
12475968
15123671
|
CSF2
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
10753826
8910448
11777960
27396825
12393492
19833085
10572088
22323450
23331499
22869907
9211889
24030977
11306493
11867689
9187659
11015446
1702217
2645577
20406969
23046136
20805416
2828352
7957082
18551128
26192618
18692472
21765015
24091328
27216177
2555171
14610620
12811837
|
CD40
|
CD86
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD86
|
CD28
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10477595
11207245
11964292
14764699
15034038
15197224
17513775
20231889
20805416
21220452
22076556
22437870
23390297
24218453
25215878
25384214
7523569
8920882
9359474
|
CD86
|
CD28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21530327
22437870
18205792
23954143
11021528
21931534
21487479
7513726
|
CAMK2B
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12475968
|
EGR2
|
CEBPB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23155406
18396140
16054051
|
CD40
|
BIRC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
19426221
12374738
24298274
9718306
|
BIRC2
|
CASP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16339151
9384571
16189514
11084335
|
HLA-DPA1
|
CTSS
|
â—¼ CLEAVAGE
|
✅
|
|
4.0
|
1.0
|
Reactome
|
11684289
12078484
12748383
8687433
|
CEBPB
|
CCNE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16120603
22722334
19407981
11162569
|
CSNK2A1
|
CDC25C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15064744
|
E2F3
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15510213
18319725
|
E2F3
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15510213
11980909
10733529
18319725
|
CSNK2A1
|
CTNNA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20858269
31432583
20093040
32256776
19941816
|
CSNK2A1
|
HES6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12972610
|
CSNK2A1
|
EIF4EBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
11146653
12588975
18212344
9806882
|
AP1G1
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CD3D
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
CD3E
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
20346773
23580664
11827988
21543337
22426112
16461343
2530588
|
DNAJC3
|
EIF2AK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
25329545
9447982
8576172
|
AMHR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16446785
14746809
11420127
|
BMP6
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11401330
10504300
|
BMP6
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
10504300
|
ACVR2B
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
23180781
8622651
16446785
12364468
18988627
|
BMP6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11401330
12297674
10504300
|
CARD16
|
CASP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11536016
11432859
|
CASP1
|
CARD8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
15383541
11051551
11821383
11536016
11432859
15030775
19337385
|
CASP1
|
CASP5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
11051551
11536016
11432859
15383541
|
HLA-DOB
|
HLA-DPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DPA1
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
CCL23
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9886417
9558365
12381680
10699158
10660125
22633458
|
CLCF1
|
CNTFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11294841
11285233
10966616
|
AMH
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8889695
23331499
8119126
16446785
18988627
79972308889695
7997230
|