Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSF4 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20620219 8972228
HSF4 HSF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
HSPB1 HSF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25036637 19597476
HSF4 HSF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21258402 25036637 33961781
DAXX HSF1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15016915 20620219
HSF4 SESD1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25036637 32296183
HSPB1 DAXX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15911090 25241761 11193028 31615977 11003656
HSF1 HSF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HSF1 SMARCA4 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CRYAB HSPB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CDK2AP2 HSF4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSF2 HSF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 26496610 26186194 26727490 28514442 12813038
TP63 HSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
HSF4 NUDT21 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSPB1 CRYAB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 23532854 12601044 20863832 1560006 28919577 26186194 17916631 28514442 11700327 18330356 23188086
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAPK1 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9649500
HSF1 CRYAB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12356732 9837746 20834230 9665826 23264262 15706094
DAXX HSPB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11003656 11274345 16406523 20452955
HSPB1 DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 25241761 11003656 11193028 15911090
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413