Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CASP3 TGM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10556977
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC42 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
VAV2 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994827 9032261
TGFBR1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 19114990
HRAS CHMP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R1A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
FNTA HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24294527 2217184
FNTA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12374986 24294527
FNTB KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12374986 24294527
HRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
TP53 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TNIK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
IKBKB TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19196987 0812256106
KRAS PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
TP53 LATS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17015431
TIPRL PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17384681
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
TP53 PRNP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24339999 19064990
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ETF1 RPL13A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CAN1 FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CJ071 DYR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TSKS PGTB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 FNTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL18 NP1L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL18 FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL18 FNTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
E41L5 FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F117B FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CJ071 FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CJ071 FNTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARNT2 FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TSKS FNTA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
FNTB CAN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DYR1A FNTA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23602568 30773093 24981860
AMERL PGTB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HEYL PGTB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PGTB1 CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15451670 31980649
NP1L1 FNTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NP1L1 E41L5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NP1L1 FNTA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AMERL FNTA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FNTB F117B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HEYL FNTA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TNIK RAP2A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15342639
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TP4A2 FNTB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28675297 17353931
TP4A2 FNTA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28675297 17353931
DYR1A FNTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 23602568 26186194
DYR1A F117B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 30773093 31024071 28514442 23602568
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PGTB1 FNTA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 24981860
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FNTB HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15451670 24294527 2217184
PPM1A IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18930133
TP53 PTP4A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
FNTA PGGT1B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
PPP2CA TIPRL â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EEF2 RPL13A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FNTA FNTB â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
INHBB ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11266516
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10224094 9463408
CASP3 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9367996 11741536
VAV2 CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10934226 11080163 11262396 12094222 14623913 15365099 15886116 9822605
DYRK1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20696760 24901999
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
FNTB FNTA â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 15248757 12036349 32296183 11687658 24981860 15170324 15451670 26186194 12825937 28514442 16189514
FNTA GNGT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 12825937 8494894 11687658 12036349
TGFBR1 FNTA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8530343
FNTB GNGT1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 12825937 8494894 11687658 12036349
HRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
VAV2 HRAS â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10934226 11080163 11262396 12094222 14623913 15365099 15886116 16713974 9822605
TP53 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21552926 9662334 11127813 21552928
KRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
TP53 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11514734 18555006 10953306 14741382 19107228 20124454 8274455 16061648 10448271
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
TGFB1 TGFBR1 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR1 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TGFB1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 22326956 10187774 7852346 22703233 12809600 7706250 11323414 8047140 8235612 26194464