AP2S1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2M1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
CAPN2
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
21887410
23242420
|
SMAD3
|
BAX
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11906909
16603637
|
BAX
|
AIFM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12232790
|
VDAC1
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0907555106
19706527
|
STAT5B
|
BCL2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16741510
18793823
|
CAPN2
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12000759
|
CAPN1
|
BCL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12000759
|
FASLG
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15659383
25241761
|
CAPN1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8695851
|
ITCH
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12226085
5215735
|
CBL
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
CBL
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
TLR4
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17126326
5219377
|
HGS
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20308550
0911188107
|
EGFR
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18776048
0806158105
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
PML
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12673202
9819401
|
EGFR
|
GRK2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5217433
15620700
|
EPN1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19054389
|
SH3KBP1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11894095
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
EGFR
|
ARF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24797263
20029029
|
VPS37C
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
HGS
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
HGS
|
VPS37A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
HGS
|
MVB12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
HGS
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
HGS
|
VPS37B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
HGS
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
23208550
8428323
|
PARP1
|
AURKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16647857
|
ZFYVE9
|
PML
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18511908
6798777
|
H2AC4
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CLTCL1
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC25A5
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC25A6
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TNFRSF1A
|
CASP8
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8095238
21157428
|
ARF6
|
PIP5K1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
12447393
15817676
|
ARF6
|
PIP5K1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10589680
|
ARAP1
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
ARPC3
|
ARPC1B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
20404198
0911668107
|
USP8
|
CHMP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
CHMP6
|
USP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
USP8
|
CHMP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
VPS37C
|
VPS36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
VPS37C
|
SNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
VPS37C
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
TGFBR2
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21358634
9679059
|
TGFBR2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21358634
9679059
|
TGFBR2
|
ARFGAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SMURF2
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22298955
15221015
|
TGFBR1
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18511908
6798777
|
ZFYVE9
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
ZFYVE9
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
19620243
9865696
|
TGFBR1
|
SMAD2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
10973958
|
SMURF2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
8308197
22045334
|
CAMK2A
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SMURF1
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
EEA1
|
IGF2R
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16977309
5219086
|
ARFGEF2
|
ARF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8945478
8945477
|
SMURF2
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
14722617
15265520
|
TGFBR1
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19726546
15761153
|
TGFBR1
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
19114990
|
HRAS
|
VPS37A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8621645
5220985
|
HRAS
|
CHMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RIPK3
|
GLUD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19632174
19498109
|
MLKL
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
31138766
24316671
|
RIPK3
|
PYGL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19632174
21903422
|
CAPZB
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PDCD6IP
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
31138766
24316671
|
CAPZA1
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSPA8
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC25A5
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
AIFM1
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ZBP1
|
RIPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32200799
19590578
|
BIRC2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17145710
12887920
|
IL2RA
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
AP2B1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2A2
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2B1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2B1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2S1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
SLC25A6
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
SLC25A5
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HSP90AB1
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
AIFM1
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TRADD
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
TNFAIP3
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12654725
|
RHOA
|
KIF5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10913441
11689693
|
STAT6
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20006706
|
CDC42
|
KIF5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10913441
11689693
|
CDC42
|
PARD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16189514
10934474
|
CBLB
|
ASAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
CBLB
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
CBLB
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLB
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
ITCH
|
CBLC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
12226085
5215735
|
CBLC
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CBLC
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
ZFYVE9
|
SPART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF2
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
19379695
9674432
|
SMURF2
|
DAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMURF2
|
SPART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
PRKCI
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5213720
11257119
|
PRKCZ
|
PARD6A
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17057644
5219258
|
RAB7A
|
DNM2
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20711168
8045116
|
PRKCZ
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18667433
17646398
|
BIRC3
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23070005
18485876
|
JAK3
|
STAT6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12207328
26758199
|
HSP90AB1
|
NLRP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
29712950
17435760
|
USP8
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
USP8
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
ARFGEF2
|
ARFGEF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19332778
0901558106
|
BIN1
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21779028
11231140
|
VPS37A
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
STAM
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
STAM
|
VPS37B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
STAM
|
MVB12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14624836
15218037
|
CHMP1A
|
USP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
CHMP3
|
STAMBP
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
RAB7A
|
SH3KBP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20711168
8045116
|
MAPK10
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19782076
7263131
|
SH3KBP1
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
5219572
17255943
|
SH3KBP1
|
ASAP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
ASAP1
|
SH3KBP1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
5219572
17255943
|
USP54
|
CHMP4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
PDCD6IP
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0707601105
18434552
|
CHMP4B
|
USP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
CHMP5
|
USP54
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
VPS36
|
MVB12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
MVB12A
|
SNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
VPS36
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
VPS37B
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
8153045
21516116
|
USP54
|
CHMP2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19302785
6946733
|
GRK2
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10085131
|
VPS4A
|
PDCD6IP
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17853893
6169256
|
VPS37A
|
SNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
SNF8
|
VPS37B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
CAPZB
|
CAPZA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SH3KBP1
|
ASAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
STAT5B
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8709637
7489741
|
IL2RA
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
CAMK2D
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20668654
1000426
|
VPS36
|
VPS37A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
VPS36
|
VPS37B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
21757351
15218037
|
SH3GLB1
|
SPART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CAV2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
CHMP4A
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
DNM2
|
DNM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
SMURF2
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5217094
15231748
|
CAV1
|
RHOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
31871319
20460433
9647788
|
PARD6A
|
PARD3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
5213720
11257119
|
ARPC5
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.81
|
0.81
|
mint
|
24981860
|
KIF5A
|
KIF5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
CHMP1A
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
ARPC1A
|
ACTR2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
24981860
|
AMPH
|
AP2M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
EGFR
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17047074
17307140
|
EGFR
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24780295
28065597
|
ARRB1
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23208550
20505072
|
HGS
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23208550
20505072
|
PYGM
|
PYGB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
33961781
|
VPS36
|
CHMP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
14505570
33961781
|
ARF1
|
ARF5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26344197
|
DAB2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22323290
34079125
|
AMPH
|
AP2S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RAB7A
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31536960
31871319
|
CAV3
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CAV1
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
19595769
|
ARRB1
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17947233
18544533
|
VDAC1
|
AIFM1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
29128334
|
ARRB2
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32962859
17620599
|
EEA1
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
12493736
10491193
|
CHMP5
|
CHMP3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ASAP3
|
ASAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ASAP3
|
ASAP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ACTR3C
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
ARF1
|
IQSEC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
821.0
|
0.82
|
STRING
|
36370105
|
EGFR
|
STAT5B
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
11751923
|
CBL
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12226085
19341794
|
EGFR
|
AP2S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24797263
25754235
24189400
|
PML
|
SMAD3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
15356634
|
PYGB
|
PYGL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25910212
25416956
32296183
33961781
|
CHMP6
|
SNF8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14505570
16371348
33961781
|
IFNA5
|
IFNA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CXCR2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16189514
11170396
|
BIRC2
|
RNF31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24726327
30561431
27545878
23524849
|
RNF31
|
CYLD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28189684
27591049
27545878
27458237
27307491
26670046
|
CASP8
|
RIPK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
19524512
30420664
22864571
19524513
|
AP2A2
|
DAB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
22323290
11247302
|
ARRB1
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33158816
15878855
21685939
|
VPS4B
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
AP2A1
|
AMPH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
12057195
33961781
|
EPN3
|
EPN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFNA2
|
IFNA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
VDAC1
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31536960
22939629
29128334
|
RUFY1
|
RUFY2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26496610
|
CHMP1B
|
VPS4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
NEDD4L
|
SMAD3
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
19917253
|
SNX2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
24797263
9819414
|
ARPC4
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.84
|
0.84
|
mint
|
24981860
|
CDC42
|
CAPZB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
31478661
31980649
|
EPN1
|
EPN3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
21115825
33961781
26186194
|
DNM1
|
DNM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
HSP90AB1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CHMP4A
|
VPS4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
CYLD
|
RNF31
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CHMP1A
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
EGFR
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24797263
24189400
7534311
23956138
|
EGFR
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24797263
8548289
24189400
23956138
31959764
|
ARF6
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11533043
16189514
11867621
|
ARF1
|
ASAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16223492
16332543
|
AP2A2
|
BIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9195986
10430869
9182529
|
CBLC
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12226085
|
PRKCZ
|
PRKCI
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
24375676
|
AIFM1
|
PGAM5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
34079125
27218139
29568061
|
SNX2
|
VPS29
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11102511
22863883
22939629
26344197
|
CHMP2A
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
CHMP2B
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
853.0
|
0.85
|
STRING
|
36370105
|
PYGB
|
PYGL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
ARF6
|
CYTH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
CHMP4B
|
VPS4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
ARFGAP1
|
ARF1
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
10102276
|
CAPZA1
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
SLC25A4
|
SLC25A5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
CASP8
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16183855
11406564
|
PLD1
|
ARF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
12379803
|
CHMP2A
|
VPS4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
RAB7A
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
26496610
|
ITCH
|
BIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26613292
28235806
|
RAB7A
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31536960
26496610
|
VPS28
|
VPS36
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
18539118
17215868
|
AP2A2
|
EPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
STAM
|
USP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
CHMP2A
|
VPS4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
BIRC2
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
861.0
|
0.86
|
STRING
|
36370105
|
BAX
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9727492
15659383
9727491
12097160
11832478
12196516
11085743
|
EGFR
|
ARRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
PLD1
|
ARF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9688545
26344197
|
CASP8
|
BIRC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12887920
27810922
15069192
22274400
|
CASP8
|
TRADD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19524513
18776134
17047155
12887920
29108854
30561431
|
AP2A1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
34079125
33961781
26344197
|
PRKCZ
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
5219258
17057644
|
PARD6A
|
PRKCZ
|
â—¼ COLOCALIZATION
|
✅
|
|
0.87
|
0.87
|
mint
|
5219258
17057644
|
RAB7A
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
29360040
26496610
|
EGFR
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
AMPH
|
AP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
PDCD6IP
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ARF1
|
ARFGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CASP8
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
USP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
BIRC2
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
RHOA
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
AP2B1
|
ARRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
ARAP1
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
CC2D1A
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
IFNA14
|
IFNA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ZFYVE9
|
SMAD3
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
20515759
|
CASP8
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CFLAR
|
ITCH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CLTB
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CAMK2D
|
CAMK2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24797263
20029029
24189400
23956138
25754235
7534311
31959764
|
IL2RB
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21362618
18445679
|
PLD1
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31871319
10747870
|
ARF1
|
ARF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
26344197
|
SMURF1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
MLKL
|
RIPK3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27560715
29883609
22265413
31358971
30420664
24316671
22265414
|
CASP8
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
AP2A2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12086608
16189514
33961781
34079125
26344197
|
ARRB2
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17947233
18544533
|
RAB7A
|
RAB5B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10329441
26344197
|
IST1
|
VPS4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
26344197
|
VPS4A
|
VPS4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
CAV1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CYTH2
|
ARF6
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
14565977
|
CHMP6
|
SNF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
STAM
|
STAMBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
TICAM2
|
TLR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CHMP1B
|
STAMBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CHMP1A
|
VPS4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
CHMP2A
|
CHMP2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
ACTR3B
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
AP2A1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
AP2M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24797263
20029029
31980649
24189400
23956138
24067654
25754235
31959764
|
AP2M1
|
AP2S1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
AP2M1
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
AP2M1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
24189400
33961781
26186194
19380743
26344197
|
AP2M1
|
EPN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
33961781
26186194
|
VDAC1
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9843949
16189514
15637055
28760928
12767928
|
CBLB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24797263
11375397
20308550
19531499
33848699
10635327
30515972
18271526
28572092
10086340
16729043
31959764
16702950
15657067
|
EGFR
|
ARF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
24797263
20029029
31980649
|
EGFR
|
HGS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23477725
12953068
20308550
23153581
23602387
25588945
18508924
15212941
|
EGFR
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
|
H2AX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
16377563
20000738
27728808
33961781
28796254
18406329
28242625
16522924
20085707
|
ARF6
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11533043
16189514
11867621
|
SMAD2
|
DAB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11387212
16713569
|
CFLAR
|
ITCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19808964
30736843
18559494
33631302
19090833
31443721
33469115
21474069
|
AMPH
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
10748223
33961781
|
AP2S1
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
12086608
16189514
33961781
34079125
26344197
|
EGFR
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
CHMP1B
|
CHMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
CHMP1A
|
STAMBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
SMURF2
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
AMPH
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
ASAP1
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CASP8
|
BID
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
9727492
|
CHMP4C
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
SMAD3
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
CAV1
|
CAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ARRB2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20947020
17199046
12958364
|
AP2B1
|
AP2M1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
12086608
16189514
16713569
24189400
33961781
19380743
26186194
30021884
34079125
26344197
|
BAX
|
BID
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
15574335
20956295
23374347
17289999
|
CAPN1
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
19931333
21887410
23242420
|
EGFR
|
CBL
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27059931
7657591
8665853
27903975
15107835
24797263
28791635
9756944
23799367
23175185
28198003
12734385
14505571
20940296
19155296
10635327
15117950
22833562
29629558
12061819
8662998
10086340
33762435
11994282
20877636
32714745
25005938
31182136
19578043
7782294
24714105
10799548
23158001
26055326
33617900
23153581
15210722
25872741
15657067
19947936
10428778
18508924
16969069
17971399
15962011
19531499
25521828
23774213
22976291
31959764
22591401
18255265
15735736
16713569
20562913
17880946
16914641
9890970
22394513
16729043
32114396
17995934
17182860
18319245
18271526
17545148
15383614
25140053
32377695
15465819
33627783
8798643
25754235
15282549
26177020
22266821
16923119
17242169
30544639
12604776
11239464
9130710
19225046
11370743
21772844
16105874
18273061
7592693
23897813
17486068
16246327
23457600
32904620
12803489
31120930
15668240
22203672
23418353
20124286
28541302
33323455
10092522
14627991
15677445
15159412
20308550
16849543
12593795
19836242
9121472
19713535
18316398
11408594
|
CBL
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18632619
17635922
10514377
|
EGFR
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
CBLC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22888118
29945960
10571044
10362357
31959764
|
EGFR
|
CAV2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
15273741
25402006
16799092
|
EGFR
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16407214
19446582
22411794
31980649
12388423
24658140
15273741
25402006
16799092
9374534
34079125
12354760
10781609
15657067
|
HGS
|
ZFYVE9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
11094085
|
PML
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
15356634
|
PLD1
|
RHOA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9565577
12593858
31871319
11311142
|
ARF6
|
PLD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
30944160
12379803
|
ARF1
|
PLD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16054594
9688545
|
ASAP2
|
ARF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10022920
10749932
|
TGFBR2
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
TGFBR2
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
TGFBR2
|
NEDD4L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
TGFBR2
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8774881
15104092
|
SMAD2
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
ITCH
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15350225
23331499
|
SMAD3
|
DAB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11387212
16189514
16713569
|
ASAP1
|
ARF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11773070
16223492
|
ARF1
|
PIP5K1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16189514
10589680
10747863
|
TGFBR1
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
TGFBR1
|
NEDD4L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15496141
11163210
11278251
|
CASP8
|
CFLAR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
22322857
24438025
12097160
33469115
19416807
22864571
9208847
9326610
17159907
11741985
15280356
19710364
21737330
31046799
21737329
9289491
17047155
9228018
12887920
9380701
33961781
26186194
12215447
19343040
|
AP2A2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20947020
17199046
12958364
|
ARRB2
|
AP2B1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21118812
17620599
12070169
10097102
|
ARRB2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
20947020
17199046
12958364
|
TRADD
|
BIRC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8943045
12887920
|
CAV2
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12414992
16189514
31980649
9361015
18081315
33961781
24013648
10212252
|
DNM2
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
PRKCZ
|
STAT6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15526032
|
CAMK2A
|
CYLD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24614225
|
CAMK2B
|
CYLD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24614225
|
ASAP2
|
ARF5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10022920
10749932
|
ARRB2
|
ARRB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24069330
17353931
33961781
17620599
|
STAM
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
0509166103
7102318
16636290
|
SNF8
|
VPS36
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18539118
14505570
28514442
32296183
17010938
16973552
33961781
11278625
16371348
26344197
|
JAK3
|
STAT5B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23109003
11406370
12495636
|
VPS4A
|
CHMP2A
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
30989108
|
SMAD2
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
BAX
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
BCL2
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
SNX2
|
VPS26B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
902.0
|
0.9
|
STRING
|
36370105
|
CLTA
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
SMAD3
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
MLKL
|
RIPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CASP8
|
TNFRSF10B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CBLB
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CHMP2B
|
VPS4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
CHMP4A
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
ZFYVE9
|
SMAD2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
20515759
|
SMAD2
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
TNFRSF1A
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
ACTR3B
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
CHMP4B
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
VPS28
|
VPS37A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
CBL
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ARFGAP1
|
ARFGAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
ARFGAP1
|
ARFGAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
AP2B1
|
EPN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
34079125
22863883
|
CHMP1B
|
VPS4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CHMP1B
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
BROX
|
CHMP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
VPS28
|
VPS36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CHMP1A
|
CHMP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
CHMP1B
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
SH3KBP1
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
6170278
12177062
|
VPS4B
|
VPS4A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
11563910
12594041
33961781
26186194
|
CHMP6
|
VPS36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
PARD6A
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
BROX
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
CHMP4B
|
CHMP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CHMP6
|
VPS4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
SHARPIN
|
RNF31
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
23032186
8410237
|
SNX4
|
BIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
31413325
12668730
|
IST1
|
VPS4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
ACTR3B
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
954.0
|
0.95
|
STRING
|
36370105
|
CBLB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CAMK2A
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CAPZA1
|
CAPZA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
958.0
|
0.95
|
STRING
|
36370105
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
16729043
5218694
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
AP2S1
|
AP2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
31353312
16189514
7593184
33961781
26344197
|
BIN1
|
AMPH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
9348539
9315708
33961781
31413325
|
ACTR3B
|
ARPC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
CAMK2B
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
ACTR3B
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
ACTR2
|
ACTR3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
ACTR3B
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CDC42
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
MVB12A
|
VPS37B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
AP2A1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
SH3KBP1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
6170483
15090612
|
ARPC4
|
ARPC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
32296183
23148219
11162547
22863883
33961781
24981860
22939629
26344197
|
ARPC3
|
ARPC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
23148219
26655834
22863883
33961781
24981860
26186194
22939629
26344197
|
AP2S1
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
33961781
26344197
|
EPN1
|
AP2A2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12057195
9723620
|
PARD3
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
CAMK2A
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
NEDD4L
|
SMAD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
CHMP4B
|
PDCD6IP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
CHMP2A
|
CHMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
ARPC1A
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
AP2A1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CHMP3
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
CAPZA2
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
SMAD2
|
ZFYVE9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
SMAD3
|
ZFYVE9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
SNX2
|
VPS29
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
PARD6A
|
PRKCI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
CHMP3
|
STAMBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
VPS26B
|
VPS29
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
ACTR3B
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
TGFBR1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ARF1
|
CYTH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ARPC2
|
ARPC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
11805826
26655834
22863883
24981860
22939629
26344197
|
ARPC2
|
ARPC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
11805826
11162547
22863883
33961781
24981860
22939629
26344197
|
TNFAIP3
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CHMP2A
|
CHMP4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
BAX
|
BCL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CBLC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
AP2A2
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CASP8
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CHMP1A
|
IST1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
VPS28
|
VPS37B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
CHMP1A
|
VPS4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
BAX
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21778226
18981409
15899854
32064756
10620799
21199865
17289999
9194558
8358790
21671007
16642033
21458670
22262057
9388232
10716992
20865015
14980220
9111042
24141421
17097560
15231068
9463381
33961781
17525735
29749471
23479509
26004684
|
BID
|
BCL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
16697956
15694340
19074266
11583631
9727491
9463381
15520201
14681455
17289999
18835031
12624108
|
ARPC2
|
ARPC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
11805826
23148219
22863883
33961781
24981860
9230079
26186194
22939629
26344197
|
ARPC4
|
ARPC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12451597
11162547
26655834
22863883
33961781
24981860
22939629
26344197
|
AP2A2
|
AMPH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
9280305
9195986
33961781
8552632
10748223
|
ACTR3
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
AP2B1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
MVB12A
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CAPZA1
|
CAPZB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
AP2B1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CHMP1B
|
IST1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
ACTR3
|
ARPC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
AP2M1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ARPC1B
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ARPC2
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
AP2A2
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
HGS
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC4
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC1A
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ARPC3
|
ARPC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PARD3
|
PRKCI
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
SNF8
|
VPS36
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ACTR3
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ACTR2
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ACTR2
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ACTR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ACTR3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR2
|
ARPC2
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
CLTCL1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
CLTB
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
AP2M1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
23956138
31980649
24189400
19351721
20029029
24797263
|
BCL2
|
BAX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
BCL2
|
BAX
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11704864
16227588
17446862
17891140
20709625
21641962
22039431
23064052
23377657
23430059
23850759
7644501
8358790
8929532
9872359
|
PRKCZ
|
BAX
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
10873802
10934475
10954424
14766748
15642728
17525161
20505164
|
BID
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20956295
17289999
25241761
19968986
15574335
10629050
19062087
10949027
12242151
23374347
14730312
17520191
8918887
|
CAPN1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20709625
21670566
21414921
16129881
17593948
14612448
21266584
|
SH3GLB1
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
19074440
11161816
11259440
16189514
16227588
|
PRKCZ
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16679323
14766748
15642728
17525161
|
BCL2
|
BAX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
60.0
|
1.0
|
Omnipath
|
17145710
22705850
18981409
9463381
21458670
17097560
17525735
8358790
10620799
26004684
29749471
9388232
21199865
17525161
22262057
21778226
15486085
17289999
9111042
12419244
9194558
15231068
10716992
8183370
14980220
9115213
21671007
16642033
23479509
10677502
|
BAX
|
VDAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16189514
10365962
9843949
12767928
|
BCL2
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16183855
11406564
|
BCL2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
18835031
17145710
9463381
16697956
17289999
19074266
12624108
11583631
9727491
15520201
8918887
|
CAPN2
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
21887410
23242420
|
CAPN1
|
BID
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
19931333
|
CAPN2
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
18469004
12000759
20709625
17264306
21670566
11404357
21738214
16129881
17593948
21266584
11940658
|
CASP8
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9727492
10364179
10805722
11832478
12196516
18458084
9727491
11085742
11085743
12097160
9873064
|
CASP1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11085743
9727491
|
CAPN1
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
18469004
12000759
20709625
17264306
21670566
11404357
21738214
16129881
17593948
16189514
21266584
11940658
|
CAPN1
|
AIFM1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
11404357
11940658
17264306
18469004
19931333
|
HGS
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
CBL
|
STAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
SH3KBP1
|
CBL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
20130058
20711168
12618476
11894095
16407834
16713569
11071869
19268472
25472714
17306257
22262777
15456872
11152963
10679202
15962011
25036637
15107835
22833562
11067845
11894096
12177062
17675467
21830225
12135478
24167568
16228008
12874286
17072306
15090612
14596919
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CAV1
|
EGFR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
CAMK2G
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
3138233
10347170
16799092
1309762
7805884
7505275
92065884
15302935
|
CAMK2A
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
17389395
17081983
3138233
20166139
10347170
15901825
16799092
18691976
8226933
20068231
1309762
7805884
92065884
1956339
7505275
18669648
15302935
|
CBLB
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
19531499
11375397
10086340
12577067
10542134
17635922
10514377
|
USP8
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16520378
16120644
25853104
20736164
|
PDCD6IP
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
31980649
15456872
12771190
24658140
15557335
25402006
|
CBLC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
10362357
22888118
17635922
10514377
|
EGFR
|
STAT5B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10830280
10358079
12411494
10558875
16729043
17016520
11751923
|
EGFR
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12953068
17016520
|
EGFR
|
ARF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12446727
|
EGFR
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17145710
31980649
22411794
9374534
19446582
16799092
12388423
15657067
24658140
19625610
16407214
18789131
25402006
15951569
10781609
16332692
|
HGS
|
CHMP2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20708039
11333915
16867982
9733768
|
HGS
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
11094085
|
PML
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
15356634
16189514
18988627
|
PML
|
ZFYVE9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
21071413
15356634
18511908
16189514
18988627
|
TRADD
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TNFRSF1A
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
35941131
22179575
22848449
23313255
24098568
34876703
16282325
20385093
22435550
18178551
19910467
|
TRADD
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TNFRSF1A
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
17145710
8565075
8943045
11934887
8612133
9915703
11684708
8621670
9430227
19641494
27552911
16611992
21760970
11821416
10187805
21724995
12721308
21741934
21232017
10795740
21119000
15310755
11502070
15115707
23955153
18776134
18939944
9916731
9129204
9082980
15485837
15173123
22297296
15357952
24130170
12887920
10634209
24758719
19524513
15465831
7758105
11035039
8791485
15725726
|
TNFRSF1A
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15357952
12887920
21741934
8875942
15725726
|
RHOA
|
PLD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11102529
12593858
9565577
11311142
|
CYTH2
|
ARF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9417041
16189514
14565977
|
ARPC1B
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ARPC2
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC3
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC3
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
VPS4A
|
CHMP2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14505570
30989108
16730941
|
VPS37C
|
MVB12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
21757351
22405001
15218037
18005716
20448139
|
VPS37C
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
21757351
22405001
15218037
18005716
20448139
|
ACTR3
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ACTR3
|
ARPC2
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC1B
|
ARPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ARPC2
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC2
|
ARPC4
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC1B
|
ARPC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ARPC4
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
ARPC4
|
ARPC5
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10467124
10511705
10783245
11395419
11520460
12177428
12194823
14707117
15001467
15541654
16293614
16606694
17306570
19741094
21178402
23212475
8625410
|
TGFBR2
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
11133108
14557817
15265520
15548370
15761148
15761153
16474430
17934056
19010789
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22315516
22703233
22949611
24132110
24336330
7594497
|
TGFBR2
|
TGFBR1
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
PARD6A
|
â—¼ SHARES_COMPLEX
|
|
|
23.0
|
1.0
|
ACSN
|
11133108
14557817
15265520
15548370
15761148
15761153
16474430
17934056
19010789
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22315516
22703233
22949611
24132110
24336330
7594497
|
TGFBR2
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
14557817
15265520
16474430
17934056
20060931
20519943
21614932
22703233
24132110
24336330
|
TGFBR2
|
PARD6A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
11133108
14557817
15265520
15548370
15761148
15761153
16474430
17934056
19010789
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22315516
22703233
22949611
24132110
24336330
7594497
|
TGFBR2
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
14557817
15265520
16474430
17934056
20060931
20519943
21614932
22703233
24132110
24336330
|
TGFBR2
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
CAV1
|
TGFBR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
DAB2
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
16713569
11387212
|
SMURF1
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11278251
15221015
22298955
15761148
21572392
27048878
22949611
|
TGFBR2
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
10678166
9463378
11792802
11133108
19920116
14557817
11278410
15178549
20060931
17934056
21614932
8980228
9311995
20519943
21900405
15548370
19010789
15104092
16474430
30093905
11274345
9865696
|
TGFBR2
|
PARD6A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15761148
25756394
24231509
23249950
19114990
|
TGFBR2
|
ZFYVE9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9865696
|
TGFBR2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
7774578
9463378
19556242
8047140
23868260
18243111
7890683
10026191
23331499
8576253
21071413
7878020
21791611
10716993
18988627
11278251
19758997
25825445
22802914
16446785
11483955
8947046
11323414
11124802
15221015
11102446
11387212
12809600
7566156
26194464
|
SMAD3
|
SMAD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
9865696
|
SMAD3
|
SMAD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10454538
10964912
11007770
11013220
11074002
11279127
11283613
11283614
11792802
12545156
12702545
12809600
15001984
15095404
15155580
15265520
16179589
16713975
17055429
17550342
17705132
18353785
18768831
19815509
19901969
20027199
20713526
21042762
21252118
21614932
2191300
22331441
23140366
23338822
23869868
8515656
9312026
9389648
9618481
9670020
9865696
|
TGFBR1
|
SMAD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
14557817
15265520
16474430
17934056
20060931
20519943
21614932
22703233
24132110
24336330
|
DAB2
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
16713569
11387212
|
CAMK2A
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11027280
|
SMURF1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10458166
23331499
15221015
20207742
15231748
|
TGFBR1
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
74.0
|
1.0
|
Omnipath
|
10678166
12220225
9892009
9463378
16024789
9136927
14625308
11792802
11133108
19920116
14557817
11278410
15134444
10085140
23331499
21071413
20060931
17934056
18511908
21614932
18988627
10973958
23221174
8980228
9311995
9346908
9235954
20519943
21900405
15350225
15548370
26057631
19010789
15104092
16474430
9346966
30093905
12957874
11744690
9525694
15212693
11274345
9865696
|
ZFYVE9
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
15613484
23331499
10615055
18729074
21071413
16916642
18511908
15356634
18988627
20515759
11094085
23687300
11243848
17272273
15231748
9865696
|
SMURF2
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
35509688
27447855
15221015
11016919
23331499
22045334
18729074
35379779
11389444
19122240
11158580
15231748
14507671
19620243
20937913
|
NEDD4L
|
SMAD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
19917253
26555259
15496141
15231748
|
SMAD2
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
21988832
26186194
12543979
9111321
15084259
9311995
25878769
18729074
12700238
|
TGFBR1
|
SMAD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
14557817
15265520
16474430
17934056
20060931
20519943
21614932
22703233
24132110
24336330
|
NEDD4L
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15496141
19917253
|
DAB2
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16713569
11387212
|
TGFBR1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
15104092
9311995
8774881
25714018
11438668
19458083
11792802
12957874
19701891
9380693
|
SMURF1
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10458166
23331499
15221015
15761153
15231748
|
ZFYVE9
|
SMAD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
26186194
18729074
15356634
25502805
20515759
31515488
16189514
12154125
15231748
9865696
|
RNF31
|
SHARPIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
RNF31
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
26997266
27591049
27545878
24098568
27458237
27307491
22435550
|
RNF31
|
SHARPIN
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11280761
11460167
14660645
17301840
18264787
21133840
21232017
24699077
24958845
|
ASAP2
|
ARF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10022920
11304556
10749932
|
ARFGAP1
|
ARF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
1010276
10102276
19020038
16189514
9733781
|
CYTH2
|
ARF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
14654833
17563369
8945478
16189514
10198630
9417041
|
TGFBR1
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
23.0
|
1.0
|
ACSN
|
11133108
14557817
15265520
15548370
15761148
15761153
16474430
17934056
19010789
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22315516
22703233
22949611
24132110
24336330
7594497
|
TGFBR1
|
PARD6A
|
â—¼ SHARES_COMPLEX
|
|
|
23.0
|
1.0
|
ACSN
|
11133108
14557817
15265520
15548370
15761148
15761153
16474430
17934056
19010789
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22315516
22703233
22949611
24132110
24336330
7594497
|
SMURF1
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
14657501
14722617
14744429
15265520
15761148
21572392
22949611
|
TGFBR1
|
PARD6A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
11133108
14557817
15265520
15548370
15761148
15761153
16474430
17934056
19010789
19109155
19920116
20060931
20519943
20644162
21278795
21614932
21900405
22315516
22703233
22949611
24132110
24336330
7594497
|
CAV1
|
TGFBR1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
11102446
17517963
18458534
19411448
20855962
21051947
21150282
21729786
22411312
22874531
23907124
25364523
26828520
|
ZFYVE9
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
9865696
23331499
12134149
14718519
12052882
18988627
|
SMURF1
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9335505
21897371
9335507
17317136
22949611
12151385
12857866
23331499
22921829
11278251
21572392
14657019
12519765
15761153
11163210
15221015
15761148
22286770
9215638
|
DAB2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
16713569
11387212
|
SMURF2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11278251
15221015
22921829
22624557
9335505
21897371
22286770
14722617
9335507
17317136
15761153
12151385
11163210
9215638
|
TGFBR1
|
PARD6A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
15761148
25756394
15761153
19114990
|
HRAS
|
PRKCZ
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
10228164
15314172
11689445
28539435
11726503
19879889
8635462
|
SMURF1
|
PARD6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
14657501
14722617
14744429
15265520
15761148
16472676
21572392
22949611
|
SMURF1
|
PARD6A
|
â—¼ PROTEIN_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
14657501
14722617
14744429
15265520
15761148
16472676
21572392
22949611
|
SMURF1
|
RHOA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
14657501
14722617
14744429
15265520
15761148
16472676
21572392
22949611
|
PARD6A
|
SMURF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21262463
15761148
19114990
|
SMURF1
|
RHOA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
15761148
21572392
16472676
16622418
28658604
15710384
14744429
14657501
22949611
|
AURKB
|
CHMP4C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
30905608
27126587
22724069
28004745
22422861
|
RIPK3
|
GLUD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
MLKL
|
GLUD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
GLUD1
|
PYGL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
GLUD1
|
PGAM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
MLKL
|
GLUD1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
GLUD1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
GLUD1
|
PGAM5
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
GLUD1
|
PYGL
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
GLUD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
MLKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
55.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
CFLAR
|
MLKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
MLKL
|
PYGL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
MLKL
|
PGAM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
MLKL
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
CFLAR
|
MLKL
|
â—¼ SHARES_COMPLEX
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
MLKL
|
â—¼ SHARES_COMPLEX
|
|
|
55.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16469705
16498403
16940415
17462996
17603935
18641653
19037093
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
20823910
20861672
21133840
21232017
22265414
22421439
22427918
23010170
23069999
23073834
23377657
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
26972597
27558815
27833036
27959630
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
MLKL
|
FASLG
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
MLKL
|
PYGL
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
MLKL
|
PGAM5
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
CFLAR
|
MLKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
MLKL
|
FASLG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
43.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK3
|
MLKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
27826146
24434512
25493335
26024392
28126382
26866270
34155344
27959630
24901049
27832137
26184911
30029665
26967968
29026104
24703947
28807105
27941671
23612963
24012422
29484439
22265413
|
RIPK3
|
PYGL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
PYGL
|
PGAM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
PYGL
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
PYGL
|
PGAM5
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK3
|
PGAM5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
PGAM5
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11274345
16469705
17603935
18641653
19037093
19498109
19524512
19524513
19632174
20823910
20861672
21133840
21232017
22265414
22421439
23010170
23073834
23627914
24366341
26024392
26587781
26653790
26807733
26853145
26900751
27558815
27833036
27959630
28498367
28574505
28645028
|
RIPK3
|
CFLAR
|
â—¼ SHARES_COMPLEX
|
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
FASLG
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
RIPK3
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19090789
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9242610
9488730
9759866
|
RIPK3
|
FASLG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
43.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16498403
16940415
17462996
18641653
19498109
19524512
19524513
19597341
19632174
19838173
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
24366341
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
CFLAR
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
CFLAR
|
FASLG
|
â—¼ SHARES_COMPLEX
|
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
CFLAR
|
FASLG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
48.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9217161
9488730
9759866
|
TNFRSF10B
|
CFLAR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15024054
20696707
19278658
10837247
19416807
21235526
|
CFLAR
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15024054
20696707
19278658
10837247
19416807
21235526
|
ITCH
|
CFLAR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
ACSN
|
10940313
11318614
16469705
16861923
18552861
18628966
21107885
21383157
26972597
|
ITCH
|
CFLAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
30736843
16469705
19090833
18786561
|
CFLAR
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
22864571
17145710
19416807
9217161
9326610
11741985
15280356
14585074
17047155
9794838
9208847
24438025
9289491
19710364
21737330
19343040
9228018
17159907
26186194
9380701
9880531
22421964
21737329
12887920
12215447
12097160
15024054
|
TNFRSF10B
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15024054
20696707
19278658
10837247
19416807
21235526
|
TLR4
|
CASP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21737330
12752666
15814722
16115877
14739303
21737329
|
CASP8
|
TICAM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
21737330
12752666
15814722
16115877
14739303
21737329
|
TRADD
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
15173123
20125124
12887920
10521396
20203691
21741934
14585074
17047155
22421964
19935698
11788820
|
TNFRSF10B
|
CASP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17047155
12721308
12218097
22421964
|
IL2RB
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RB
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
JAK3
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
7693677
16189514
10825200
7973659
9553136
7973657
|
IL2RB
|
IL2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8568232
15265897
11886175
15933202
15178252
1545122
8260650
3116143
8006584
|
TLR4
|
TICAM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
22139835
21903422
16410796
14556004
14517278
14519765
24265315
21829704
18221795
25736436
17258210
|
AP2A2
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
AP2A2
|
CLTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
CLTCL1
|
AP2B1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
CLTCL1
|
AP2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
BIRC3
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
35941131
22179575
22848449
23313255
24098568
34876703
16282325
20385093
22435550
18178551
19910467
|
BIRC2
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
35941131
22179575
22848449
23313255
24098568
34876703
16282325
20385093
22435550
18178551
19910467
|
TNFRSF10B
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9430228
9430227
|
PARD6A
|
RHOA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
8.0
|
1.0
|
ACSN
|
14657501
14722617
14744429
15265520
15761148
16472676
21572392
22949611
|
STAT6
|
RHOA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19857574
20859068
20006706
|
WIPF3
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11340081
11829459
10878810
12213210
11553796
10781580
11157975
|
CDC42
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16714282
7512369
9113980
23434736
11306516
|
CDC42
|
PARD6A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10934474
14676191
10873802
11260256
16189514
12606577
|
CDC42
|
PRKCZ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23109003
17353362
10733591
10873802
|
SHARPIN
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
26997266
27591049
27545878
24098568
27458237
27307491
22435550
|
CLTA
|
DNM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
14731593
2121367
9497313
8939989
|
CLTA
|
DNM2
|
â—¼ GTPASE_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
10480952
7650016
7592972
10593899
2121367
9497313
8939989
|
SPART
|
ITCH
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16055720
19580544
19307600
19765186
20504295
|
ITCH
|
SPART
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16055720
19580544
20719964
19307600
19765186
20504295
|
PRKCZ
|
PARD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24152735
23109003
17353362
12390250
|
AP2A1
|
CLTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
AP2A1
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
Reactome
|
1847920
20448150
10559856
19713939
19776351
21883765
15916959
26403691
22863004
23891661
19809571
21445324
15339664
21613550
21779028
19296720
|
STAT6
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9651359
7796300
23124025
15805299
8085155
|
STAT6
|
ALOX15
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11509556
18799463
23285160
10657944
12517954
|
USP8
|
STAM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16520378
10982817
20736164
|
MAPK10
|
KIF5C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24953741
26794516
19525941
|
CLTB
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9100026
6146630
17978091
26042225
20033059
|
HSPA8
|
CLTCL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9100026
6146630
17978091
26042225
20033059
|
ARF4
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
23945166
9819391
19153612
18685082
22983554
16431365
16038802
16136078
23567335
|
ARRB2
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19782076
11090355
18408005
11356842
|
STAM
|
SH3KBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
JAK3
|
STAM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
10899310
9133424
16189514
|
CHMP1A
|
VPS4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
17928862
16730941
23045692
14505570
11559748
|
PRKCI
|
PARD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17145710
14676191
22579248
27554858
|
ARRB1
|
MAPK10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19782076
11356842
19879840
|
RAB8A
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
20308558
22433857
22983554
12221131
23567335
21273506
|
VPS37A
|
MVB12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
21757351
22405001
15218037
18005716
20448139
|
VPS37A
|
VPS28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
21757351
22405001
15218037
18005716
20448139
|
ARPC1B
|
ARPC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
CCR5
|
JAK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23109003
11406370
12495636
17169327
|