Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
POMC MC4R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1325670 6274691
AGRP MC1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14535656 20371771
KLF4 ATF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21205742
FOXO1 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18375530
FOXO1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25510553 19049975
STAT3 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129668
POMC MC1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1325670 6274691
POMC MC3R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1325670 6274691
POMC MC5R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1325670 6274691
AGRP ASB7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGRP KITH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGRP NOTC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGRP NHLC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGRP BIRC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGRP GRN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AGRP MC4R â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10318826 11747427 12815165
POMC MC2R â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1325670 8463333 14463577
POMC MC4R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 8884876 9058374 11024027 10493100 12165561 20371771 11101306 20694162
AGRP MC4R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 9311920 10318826 9299416 20371771 12815165 11747427
FOXO1 AGRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23462798 16604086 28270795 16783365
AGRP MC5R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9892020 20371771 98920209892020
AGRP MC3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9819197 9893984 9311920 10318826 20371771 11747427
FOXO1 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19049975 23370526 16783365 28270795
LEPR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11018044 21166956 8608603 18718905 11445068
POMC MC1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 12007532 19656324 11041375 10942578 1516719 20371771 7774675
POMC MC2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12213892 9058374 905837412213892 20371771
POMC MC3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 11024027 10493100 10358030 17702843 20371771 7774675
POMC MC5R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 12007532 11606131 11785979 8185570 20371771 7774675
STAT3 POMC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23370526 17023536 19049975 12239103 10196143 11104795 12697721 12639901