TP53
|
BAD
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17000778
22869582
|
IKBKB
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23332762
|
FAS
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15659383
25241761
|
FADD
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15659383
25241761
|
HLA-DRA
|
CD74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218024
16242130
|
CD74
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218024
16242130
|
HLA-DMB
|
CD74
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
2391366
8574855
|
HLA-DMA
|
CD74
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
2391366
8574855
|
EIF2AK3
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19029953
|
TRAF2
|
IKBKE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
IFIH1
|
IKBKE
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0700544104
17600090
|
IKBKE
|
IFIH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0700544104
17600090
|
IKBKE
|
STING1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0900850106
19433799
|
IRF3
|
IKBKE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20304918
21182093
|
FADD
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16227629
23131831
|
TRAF2
|
IRF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15361868
19479062
|
MAVS
|
IRF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15361868
19479062
|
IRF7
|
IFIH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15361868
19479062
|
IRF9
|
IRF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10924517
12768031
|
STAT2
|
IRF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10924517
12768031
|
IRF7
|
IFNA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19349300
12242290
|
IRF7
|
IFNA7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10938111
19349300
|
IRF7
|
TAP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16014964
11119603
|
IRF7
|
IFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16410796
|
MTOR
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
MTOR
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5214238
11438723
|
AKT1
|
MTOR
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17611497
18954143
|
TNFRSF1A
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
11786908
6731384
|
IFNB1
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10022928
18508557
|
STAT2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10022928
18508557
|
IFNAR1
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10022928
18508557
|
TYK2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
10022928
18508557
|
PTPN11
|
SRC
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8288622
20308328
|
TYK2
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9794795
|
TP53
|
PPP1CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
TP53
|
HLA-A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15501971
12857899
|
TP53
|
HLA-E
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1400626
1652755
|
TP53
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17564708
24180280
|
TP53
|
EIF2AK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19416861
10082513
|
IKBKB
|
TP53
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19196987
0812256106
|
PIK3R3
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
32606738
|
TP53
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16917513
|
TP53
|
TAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
FAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9841917
|
IFIH1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16153868
19479062
|
TRAF6
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19713527
|
IRF3
|
IFNA7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19349300
12821121
|
STING1
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22394562
18818105
|
IRF3
|
CCL5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11991981
|
IRF3
|
IFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16410796
|
SOCS3
|
IFNG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10421843
10064597
|
SOCS3
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10421843
10064597
|
SOCS3
|
IFNGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10421843
10064597
|
SOCS3
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10421843
10064597
|
NFKB1
|
SOCS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23335796
|
FADD
|
FAS
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16498403
5218359
|
MAP3K7
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219785
17363973
|
MAP3K7
|
CARD9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22069318
20038579
|
ZNF205
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
TRAF2
|
IFIH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16153868
19479062
|
IFNGR2
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15120645
23331499
|
IFNB1
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10918594
|
IL1B
|
IRAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12538665
17507369
|
IFNGR1
|
IFNG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
376230
7617032
|
IFNAR1
|
IFNGR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18929502
23331499
|
STAT2
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9218597
21178011
|
IFNB1
|
TYK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10542297
|
TYK2
|
EIF2AK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23236554
17290288
|
EIF2S1
|
EIF2AK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9431994
6735217
|
EIF2S1
|
EIF2AK2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
9431994
6735217
|
EIF2B2
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8887689
15054402
|
RELA
|
POU2F2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9360945
|
RELA
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
12842894
5216511
|
PIK3R2
|
HLA-E
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
HLA-E
|
PIK3CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15536084
11907067
|
NFKB1
|
HLA-E
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
1423646
8428579
|
PPP1CA
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8288823
20186153
|
ALYREF
|
AKT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18562279
0802533105
|
NFKB1
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18031796
|
PPP1CA
|
AKT1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8288823
20186153
|
PPP1CA
|
AKT1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8288823
20186153
|
NFKB1
|
TAPBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18694960
|
NFKB1
|
POU2F2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9360945
|
NFKB1
|
TAP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18694960
|
NFKB1
|
HLA-F
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9725221
11137213
|
NFKB1
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9294162
9733516
|
IKBKB
|
EIF2AK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10848580
16600570
|
PDIA3
|
ZNF101
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PDIA3
|
ZNF181
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TAPBP
|
PDIA3
|
â—¼ DISULFIDE_BOND
|
✅
|
|
2.0
|
0.8
|
intact
|
17170699
5219449
|
HLA-DRA
|
HLA-DQA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8520027
9850860
|
PPP1CA
|
IFIH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23499489
|
IRF9
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7843405
20038197
|
JAK1
|
SOCS3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
10707961
10373548
|
IKBKG
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
812.0
|
0.81
|
STRING
|
36370105
|
AKT3
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AKT1
|
BAD
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
9346240
|
TSC2
|
MTOR
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
0.82
|
0.82
|
Signor
|
12271141
|
TNFRSF1A
|
TRAF2
|
â—¼ UP_REGULATES
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
10795740
|
TRAF2
|
MTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14743216
25241761
|
TRAF6
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20097753
24464131
23524849
29545793
|
IFNA5
|
IFNA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
MAVS
|
TRAF5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27348524
31806368
20161788
31390091
26221961
|
IFNA2
|
IFNA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
EIF2B5
|
EIF2S1
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
15054402
|
IKBKB
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
JAK1
|
TYK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8702790
7589562
|
MAVS
|
TRAF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
BIRC3
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
TRAF6
|
TICAM1
|
â—¼ POLYUBIQUITINATION
|
✅
|
+
|
0.84
|
0.84
|
Signor
|
20047764
|
IKBKB
|
NFKB1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
11158290
|
TRAF6
|
IRF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18710948
30927622
21743479
21183682
15361868
22095711
26224488
|
RHEB
|
MTOR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
18550814
16098514
16915281
15854902
33157014
15772076
15878852
25351248
|
IRAK4
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
23381138
16189514
11960013
|
TRAF5
|
TRAF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9718306
32296183
21903422
|
SRSF3
|
SRPK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
23602568
|
TRAF6
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10635328
16189514
22447928
29545793
|
AKT1
|
FAS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25640309
31980649
|
IKBKG
|
RELA
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
15489227
|
CD74
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
TRAF6
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
8153045
21516116
|
IRF3
|
MAVS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16153868
22908223
25636800
24379373
21903422
|
TRAF2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
IKBKE
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MAP3K7
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IFNAR1
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
IFIH1
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MAVS
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
PIK3R2
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
MAP3K7
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
TAP1
|
TAPBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
IKBKE
|
IRF3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
IRF3
|
MAVS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
IKBKB
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
IRF7
|
IRF3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18641315
11162841
|
TRAF6
|
TRAF5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
8153045
21516116
|
TRAF2
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
32296183
16189514
16260598
21782231
16713569
25416956
9500555
33961781
21516116
21903422
|
TRAF5
|
TRAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32296183
22493164
25416956
29176576
33539883
21516116
27107012
|
HCFC1
|
HCFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
24981860
15199122
|
MAVS
|
IFIH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22623778
16127453
19881509
19416887
32612200
22301138
17600090
33372174
33649232
30193849
27312109
21903422
|
IKBKG
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
EIF2B4
|
EIF2S1
|
â—¼ GTPASE_REACTION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
15054402
|
IRF7
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
IKBKB
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
TICAM1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
EIF2AK1
|
EIF2S1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
10563826
|
HLA-A
|
PDIA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
AKT1
|
TSC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12438239
12150915
15342917
12167664
|
MAVS
|
TRAF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32296183
27348524
16153868
31806368
30527812
29125880
33582548
32877691
26221961
21516116
31390091
30561431
21903422
|
PDIA3
|
TAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
9545232
17055437
11823531
30833792
|
PDIA3
|
TAPBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
892.0
|
0.89
|
STRING
|
36370105
|
SRSF3
|
SRSF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
BIRC3
|
CASP9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
IKBKB
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
IKBKB
|
MAP3K7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
897.0
|
0.89
|
STRING
|
36370105
|
CASP9
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16701639
25241761
21988832
16339151
9545235
15069192
|
RELA
|
CD74
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8164652
|
NFKB1
|
CD74
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8164652
|
TP53
|
CD74
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12527807
8948636
11956069
|
IKBKG
|
IKBKB
|
â—¼ PHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
intact
|
8209688
506093200
16126728
|
IKBKG
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15489227
|
IRF7
|
IRAK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15361868
15767370
15492225
|
IRF3
|
IRF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20483755
15367631
15664995
|
MAVS
|
IRF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17020950
16153868
|
MTOR
|
AKT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
18566587
25792870
15718470
14970221
24670654
10910062
18505677
29567957
22337773
21177249
26293922
19299511
18566586
30639242
21045808
11438723
22084251
23872070
21343617
22307628
|
TYK2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15919823
7512451
20671117
|
TAP2
|
TAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
11133832
12213826
19297616
11381133
17055437
26789246
33961781
16828748
18802093
30833792
19201886
|
TP53
|
ZNF611
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
TP53
|
ZFP37
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
TP53
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17409411
18431400
|
TRAF6
|
MAVS
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
27348524
16153868
20080758
31806368
22908223
30527812
29125880
23545497
32511263
26385923
26221961
31390091
21903422
|
SOCS3
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
18055217
16543409
|
TRAF6
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
34938598
19713527
|
IRF3
|
IFIH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12692549
16153868
16846591
|
RELA
|
SOCS3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23386688
23335796
|
RHEB
|
TSC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12869586
12820960
30514904
12842888
17077083
15854902
12771962
|
AKT3
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12150915
12167664
12172553
|
LTA
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8663299
9122217
12571250
|
IRF9
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8864350
22252317
9218597
|
IL12B
|
TYK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
EIF2B4
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16288713
8887689
15054402
|
SRC
|
PIK3R3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25814554
22402981
|
STAT2
|
IRF9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
8943351
17923090
24065129
33961781
9242679
21903422
|
NFKB1
|
LTA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2104232
19126379
18990758
|
HLA-DRA
|
HLA-DQA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9312039
1956401
16618111
|
POU2F2
|
HLA-DRA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9823775
7629508
|
SRSF3
|
NXF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18364396
17036044
|
PIK3R2
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22402981
8596638
11733063
|
LTA
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8663299
9122217
12571250
|
BIRC3
|
TRAF2
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
18997794
|
AKT1
|
MTOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
EIF2AK2
|
EIF2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
EIF2AK4
|
EIF2S1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
32513922
|
TRAF6
|
MAP3K7
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
18758450
|
TYK2
|
IFNAR1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
8605876
|
TSC2
|
RHEB
|
â—¼ GTPASE_REACTION
|
✅
|
-
|
0.91
|
0.91
|
Signor
|
15340059
|
IRF9
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
BCL2L1
|
BID
|
â—¼ PHYSICAL_INTERACTION
|
|
|
921.0
|
0.92
|
STRING
|
36370105
|
MTOR
|
AKT1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.92
|
0.92
|
Signor
|
21592956
|
TNFRSF1A
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
C3
|
CFP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
BAD
|
BCL2L1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
PIK3CB
|
PIK3R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
IKBKG
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
HLA-DMA
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15998799
10358075
25241761
11500364
9381178
11994280
23085457
15722337
19667065
15784622
|
FAS
|
FADD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
5219431
17159907
|
FAS
|
FADD
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16498403
5218359
|
HLA-DRA
|
HLA-DRB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
962.0
|
0.96
|
STRING
|
36370105
|
IKBKB
|
NFKB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
HLA-DMB
|
HLA-DRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
963.0
|
0.96
|
STRING
|
36370105
|
IFNA2
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
HLA-A
|
TAPBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
TRAF2
|
BIRC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25241761
30948266
10753917
21988832
9384571
20385093
19815541
20562859
8643514
16891304
16282325
24464131
8548810
11907583
21331077
27534557
23524849
15310755
23543740
16713569
23007157
33961781
|
RHEB
|
TSC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
IFNAR1
|
TYK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
TAP1
|
TAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
HLA-DMA
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
BCL2L1
|
BAD
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
11583631
5214629
|
IKBKG
|
IKBKB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219009
16938294
|
IKBKB
|
IKBKG
|
â—¼ PHOSPHORYLATION
|
✅
|
|
0.98
|
0.98
|
mint
|
8209688
16126728
506093200
|
MAVS
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
BIRC3
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
MTOR
|
RHEB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
LTA
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
MAP3K7
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
EIF2B2
|
EIF2B5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EIF2B4
|
EIF2B5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EIF2B2
|
EIF2S1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
EIF2B2
|
EIF2B4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
IKBKB
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
AKT1
|
BAD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
PPP1CA
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17145710
10811615
17274640
22820751
|
AKT3
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
26.0
|
1.0
|
Omnipath
|
9346240
11493700
20398329
21506126
9381178
20028971
12040186
21303971
15280015
20214616
10230394
10558990
8929531
10837486
11882383
10611223
23109003
12954615
22094462
10949026
15023346
17680028
18218901
17270021
|
AKT1
|
BAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
137.0
|
1.0
|
Omnipath
|
10880354
19052636
21506126
20028971
21303971
20214616
11994280
8929531
17570479
12832477
17555943
25241761
11715018
18636226
21998731
9812896
17680028
11500364
18385666
18707149
10201527
18218901
11983683
10490655
19030972
19667065
11756412
11020382
16931767
18372248
15808505
20138985
18046313
18669648
19121340
19703413
11714830
10949026
15972258
16341064
10358075
23085457
18220336
10516287
12897128
9580112
9651683
11923280
9346240
16697215
19690332
11493700
15452053
12040186
10826997
12175651
15722337
14737178
11882383
15226424
10521512
15023346
15784622
17052453
16044149
16403219
12444011
20166139
20398329
9381178
11544290
15037618
12767520
15280015
10230394
10558990
15998799
10082559
11577096
10837486
15169778
10611223
23109003
12954615
22094462
11438654
11312610
11254732
21540285
10383455
19664994
10722653
20832730
18570873
10926925
17270021
|
BAD
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
79.0
|
1.0
|
Omnipath
|
9305851
22705850
9389483
11483855
16697956
19667065
18628207
11907096
25416956
10620799
31467278
32814053
20837658
9388232
11077446
21988832
26871637
11206074
8929531
16189514
7834748
19427857
12115603
11494146
26186194
15694340
25241761
23109003
20603619
32296183
15705582
15131699
29997244
9372935
11583631
31515488
9824152
|
RELA
|
BCL2L1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15079071
15536066
17550372
19171876
23430059
8383323
9743347
|
RELA
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10925251
17673602
14978135
20585448
15231833
14739605
10585435
20066113
16904634
9439816
10733571
15756023
15986355
21722408
12226754
15856023
16453001
18223231
19706766
|
NFKB1
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10925251
17673602
12176906
11992002
14978135
15231833
14739605
10585435
20066113
16904634
9439816
18222423
10733571
15756023
15986355
12226754
15856023
16453001
11756417
18223231
|
TP53
|
BCL2L1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22869582
9582400
9989972
11713584
18172861
23519249
12705879
9000137
11713302
|
AKT1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
20138985
15169778
9812896
17680028
11756412
11923280
20214616
16697215
10949026
10722653
20832730
18570873
18372248
11715018
20398329
17052453
18636226
15808505
|
NFKB1
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10428780
19211554
10435632
10428030
11756417
|
BID
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
9727492
19074440
16697956
15694340
17289999
25241761
22464442
14963330
16189514
27159560
24814347
15574335
|
TP53
|
BCL2L1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
BCL2L1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16189514
25241761
9539746
|
BCL2L1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
24814347
12667443
16151013
26556313
14963330
16713569
20837658
24474649
21900206
|
TP53
|
BID
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12402042
16151013
18574470
|
TP53
|
BID
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15240700
12402042
18431400
15024076
|
AKT1
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
11756412
11923280
16697215
20398329
18372248
15004527
15808505
20138985
20214616
15703181
17570479
28177918
18840507
15169778
11714830
10949026
16341064
11715018
18636226
10529400
9812896
17680028
19440551
10722653
20832730
18570873
17052453
|
PPP1CA
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22311969
12792650
16888006
|
AKT3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9812896
|
BIRC3
|
CASP9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
16339151
21988832
9990849
15069192
25241761
9545235
16701639
|
CD74
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
CD74
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
CD74
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
EIF2S1
|
EIF2AK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
18664456
12370288
16288713
17956313
11907036
10026192
|
EIF2AK3
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
76.0
|
1.0
|
Omnipath
|
25429617
25579745
14967143
17998059
21981022
27009865
10504407
23356742
3352609
26622781
24316205
24706853
16288713
20408811
30070006
18840095
27638465
21844328
21029306
23293645
21901118
29199180
30081573
14638860
19007793
9819435
23935851
8099443
21029301
19220912
31226023
25660019
22509299
22169477
11337501
24904562
15314157
9930704
23314846
17998206
17325203
16179258
25393282
19583950
26028033
29396442
26487695
10542257
18694499
1677563
11555640
24705207
20040105
24159375
25541374
24958502
11907036
29163417
|
EIF2AK4
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
22593757
28781602
15684420
10504407
3352609
24706853
20454906
9819435
8099443
15550948
27613409
11337501
32513922
9930704
29281830
21919885
17940089
22355110
16179258
30196486
19583950
28671615
10542257
1677563
25079372
15355306
|
IKBKE
|
TICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
Reactome
|
12692549
15210742
16306936
16281057
14530355
17526488
17047224
14703513
23453971
|
IFIH1
|
IKBKE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
16177806
17020950
15210742
15210743
16306936
16127453
12702806
16858409
|
MAVS
|
IKBKE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
17145710
15210743
16127453
19153231
17020950
25636800
15210742
16306936
12702806
16177806
27419230
36056146
19546225
19380491
16858409
21200404
24706939
18207245
17468758
17327220
|
TICAM1
|
IKBKE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14739303
16410796
12692549
16281057
|
IKBKE
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
16127453
19153231
12692549
24722368
15210742
20532218
12702806
16380379
14703513
29800227
14679297
17706453
24396068
18440553
16281057
16625202
9463386
18818105
16199137
9566918
15695821
14739303
21138416
17526488
15212693
16914100
|
IKBKE
|
IRF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
16625202
25225665
9786932
15210742
22787218
10893229
26712804
16127453
12702806
16380379
15367631
12692549
17706453
16199137
16914100
|
IKBKE
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
28317833
12842894
16046471
20188669
15128824
17561400
17003035
30223576
15485852
10521409
15489227
15849198
16407239
26025205
15212693
12767944
|
TICAM1
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15064760
15814722
16115877
16603398
16547522
|
TRAF6
|
IKBKG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
18180283
18347055
21220427
16547522
|
RELA
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
TRAF2
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
NFKB1
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
MAP3K7
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10391247
11280761
11460167
11477091
12620219
14633987
14660645
15082531
15125833
16603398
16799562
17301840
17363905
18264787
18641653
19161412
20164171
21041997
21133840
21232017
22941947
23681101
24403530
24699077
24958845
|
FADD
|
IKBKG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
IKBKG
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
38.0
|
1.0
|
ACSN
|
11280761
11438547
11460167
12133805
12811837
14660645
15145317
15199157
15485931
15536066
15573129
16818229
16970925
17237376
17254973
17301840
17363905
17485448
17693255
18264787
18716620
19833085
20138012
20300203
21133840
21217011
21232017
21807870
22435554
23086447
23422957
23430059
24378531
24699077
24766893
24958845
2649237
28462531
|
TRAF2
|
IKBKG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
84.0
|
1.0
|
ACSN
|
10542212
10754326
10820262
10925299
10952726
11112697
11274345
11280761
11438547
11460167
11875494
12133805
12433365
12646658
12811837
12907458
1431106
14607933
14625680
14660645
15099563
15199157
15465827
15485931
15536066
15592525
15644117
15699106
15749903
16243976
16413922
16713974
16818229
16878026
16970925
17237376
17254973
17301840
17363905
17404308
17462996
17485448
17693255
17916596
18264787
18345002
18633355
18641653
18716620
19392652
19411070
20038811
20138012
20184663
20300203
20435894
21133840
21217011
21232017
21411734
21807870
21826665
22435554
22955274
23086447
23170255
23390297
23422957
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
2649237
28462531
7594497
8910423
9743347
|
TRAF6
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
17562858
17728323
17947236
14695475
18180283
15620648
15125833
12867425
11057907
|
NFKB1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
MAP3K7
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
24911653
11477091
17301840
18180283
19909372
15125833
24699077
17363905
16356855
18641653
24403530
18079694
18223652
14514672
17496917
19531477
20300203
11325957
21133840
21232017
18264787
9744859
10391247
16799562
15836773
10702308
23109003
12620219
14633987
17363973
19161412
22941947
23681101
17047224
29145629
11280761
16301747
15082531
26192618
14660645
20038579
24958845
15327770
20164171
11460167
16603398
21041997
|
AKT1
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20837477
20098747
17660512
|
TNFRSF1A
|
IKBKG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16189514
10755617
|
IKBKG
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
150.0
|
1.0
|
Omnipath
|
17145710
16938294
20932476
35339487
18266324
16260493
27929056
25979343
19666608
26496610
12133833
12192055
9751060
21423167
19706536
15836773
17561400
22099304
23986494
19959994
15327770
25400026
24266532
18450452
12657630
20434986
11583588
20200955
20300203
21903422
22990857
14743216
20167598
20098747
16126728
19656241
25852190
16906147
10195894
17000764
18329793
16186825
16547522
16611882
18037881
10968790
16497931
25286246
18462684
18207244
16603398
17965022
17977820
24240172
17568778
15084594
16129692
23506214
16319058
23123196
18949366
15218526
22605335
20368414
10837071
19820708
10980203
23131831
17363973
15214841
25304104
16493424
15184390
15691841
11864612
15802604
17693255
21455180
11865184
20211142
11971985
16970925
24469399
24618592
12486103
11057907
24369075
19365808
18583959
27426725
12612076
19422324
10094049
23109003
21803029
12459277
21640763
16285893
18266467
12709429
15620648
17072322
19815509
15749833
|
IKBKG
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14743216
|
TICAM1
|
IRF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15210742
16281057
14703513
9566918
17157040
|
RELA
|
IRF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15265881
16982926
11877397
|
NFKB1
|
IRF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15265881
16982926
11877397
|
IRF7
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
22547704
24532789
12604599
15355347
16186222
12915551
16014964
22065573
19176627
23906644
17785777
22698399
17236232
9877175
10938111
11303025
19557165
21994549
10848607
20637800
19349300
14729983
10692430
20581830
11846976
20483755
12821121
19570869
|
IRF7
|
IFNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10938111
11473119
19349300
17236232
10692430
|
TRAF6
|
IRF7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22095711
18710948
21743479
30927622
15361868
|
MTOR
|
IFNG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
12150925
12408816
12906785
15755954
16469695
17604271
17680028
18372248
18492954
19022819
19143636
19446321
19568798
19706736
19864431
20805416
21157483
21981924
22504639
23087689
24795729
24973821
25002027
25730849
26159692
28216025
|
MTOR
|
AKT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
45.0
|
1.0
|
ACSN
|
10722653
10949026
11274345
11715018
11756412
11756498
11923280
12408816
12906785
15169778
15808505
16469695
16697215
17052453
17461779
17680028
18000759
18372248
18492954
18570873
18636226
18925875
19022819
19143635
19151919
19568798
19720745
20027184
20138985
20214616
20338997
20398329
20832730
21157483
21474067
21981924
23087689
24795729
24973821
25002027
25730849
26159692
27331412
28216025
9812896
|
RHEB
|
MTOR
|
â—¼ UP_REGULATES
|
✅
|
|
7.0
|
1.0
|
ACSN
|
12906785
16636147
17604271
18466115
19022819
19143635
23087689
|
RHEB
|
MTOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
18670866
18075516
18550814
16631613
18466115
16915281
23331499
15772076
16098514
20006481
15878852
21071413
23272152
19299511
15854902
19487463
20226003
19143635
17604271
16636147
17470430
12906785
|
MTOR
|
AKT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17517883
18372248
19203586
17277771
15718470
|
MTOR
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
80.0
|
1.0
|
Omnipath
|
18000759
20027184
21157483
11756412
11923280
24670654
16697215
11438723
21592956
20398329
17461779
18372248
21177249
21045808
20338997
15808505
16221682
20138985
20489726
15899889
20214616
8978681
21474067
14970221
19203586
17660512
15718470
19568798
20333297
23006971
15169778
25241761
18566586
19720745
17517883
18925875
22084251
10949026
14761976
11715018
19143635
17277771
18636226
10910062
15047712
9812896
18505677
21343617
19844585
17680028
19151919
18566587
9736715
23872070
10722653
20832730
18570873
17013611
17052453
12408816
15364915
11274345
|
HLA-B
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11513144
11994457
8976179
8986721
9605119
9751747
|
HLA-E
|
PTPN11
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10358164
11015446
11062502
12731048
15120186
15536084
22464172
2731048
8478617
9485206
9486650
9655483
|
PTPN11
|
IL1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
1238444
12393695
12421919
12707331
15169881
15240681
15699106
15713798
16204085
17307799
19406987
19479342
19833085
20363967
20435894
21469115
22483603
22683124
22955274
27557510
9751747
|
PTPN11
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
34.0
|
1.0
|
ACSN
|
10358138
11447289
11449354
11572860
12138178
12176909
1238444
12393695
12421919
12707331
12773515
12917349
15169881
15240681
15699106
15713798
16204085
19833085
20363967
20435894
21469115
22483603
22513334
22683124
22952938
22955274
25355530
26667266
26755705
27474009
8976179
8986721
9751747
9765283
|
HLA-DQA1
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
HLA-DRA
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
12947224
15358536
18173375
18759926
|
JAK1
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23331499
8790359
21071413
8995399
12270932
12403768
9794795
11036942
|
SOCS3
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
12403768
17138568
11356008
10777583
|
PTPN11
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
18950707
23109003
16371368
17722974
22315502
16107703
9660791
8080844
9632795
15790353
|
PTPN11
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
18757826
18482983
10698938
17974954
14687660
24632723
20308328
|
TAP2
|
TAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
10973281
11717192
14508489
16181333
17204652
22076556
22790179
|
TAP2
|
TAP1
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
10973281
11717192
14508489
16181333
17204652
22076556
22790179
|
TRAF2
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TNFRSF1A
|
BIRC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
35941131
22179575
22848449
23313255
24098568
34876703
16282325
20385093
22435550
18178551
19910467
|
TRAF2
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRAF2
|
TNFRSF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
LTA
|
TNFRSF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8171323
8182064
8288897
2170974
16189514
8387891
7995952
12387745
1310388
|
TNFRSF1A
|
FADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21760970
15357952
15033800
21741934
9129204
|
TNFRSF1A
|
TRAF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
26212014
8565075
8943045
8612133
16713569
16611992
22179575
11821416
7544915
12721308
21741934
10795740
21119000
19150425
27321185
25241761
15115707
18776134
15743837
15485837
20448643
12887920
24735611
20333651
18022363
19815541
|
RELA
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
18269916
10348347
11032029
8051093
20061391
15155458
21332394
9890939
21887328
|
NFKB1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10348347
11032029
8051093
12145335
20097177
|
TP53
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10101800
12788915
15580300
16317104
16322229
14719118
16557594
20797428
11103825
19615968
7539102
12447615
12944915
12963547
11313989
16951143
9841917
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
EIF2AK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17451862
16083285
1088347
10082513
10348343
10884347
16552184
9315650
9737981
19413330
16713569
10747897
|
PPP1CA
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
16501611
16713569
15231748
15178317
|
TRAF6
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11274345
12150927
12620219
14660645
15125833
16252010
17948050
18264787
18758450
18922473
19161412
|
IRAK4
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12496252
16189514
11960013
|
TICAM1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
19795416
15932500
16410796
14530355
14739303
14982987
24812060
14751757
20047764
25736436
15474016
16281057
|
TRAF6
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16260493
15691841
15620648
15327770
10195894
16186825
16493424
17965022
10094049
10837071
|
TRAF6
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
19675569
17947236
19843958
10882101
19521662
11259596
17079228
28024152
31885808
19112497
22924441
10094049
27501752
18922473
11518704
11809792
16517750
19232515
10702308
16410796
14633987
19820695
22851693
10921914
18758450
12496252
12609980
21822258
12242293
25963657
24434549
27249171
22643835
21245467
17965022
26038599
|
IRF3
|
STING1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
12133833
15210742
22394562
16281057
18818105
16306936
19926846
19776740
22579474
19433799
24560620
|
IRF3
|
IFNA2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10938111
11473119
12821121
19349300
24185615
10692430
|
IRF3
|
IFNA5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20638368
19349300
18851954
12242290
|
IRF3
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
84.0
|
1.0
|
Omnipath
|
19108859
22911767
20453844
22684309
15857993
17540767
16699525
9891032
24185615
12885884
16125763
19349300
20581830
11846976
20610716
16954376
23911869
9707562
12821121
18851954
26483348
23096996
12604599
12829834
22065573
19176627
9649509
20375222
24180280
27481269
18539711
21492741
19570869
20048166
16641293
20304918
15955070
25531393
18641315
19153231
24257594
20130065
16186222
15699120
12077266
17785777
17243100
22285490
9877175
11303025
22417706
23843640
21148557
18225953
17692882
21281747
11222729
9541017
20660350
21228327
17652396
18614628
19541850
20083668
24532789
22902624
18272195
17079289
21632562
17079305
17496231
22083261
10938111
19846511
10848607
17845078
9446577
10692430
18309294
20483755
17947522
24656046
17296604
|
IKBKB
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
25070846
20604809
9566918
14703513
19153595
27992402
18272581
16914100
|
MAVS
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17020950
25636800
21903422
16153868
22750291
|
TICAM1
|
IRF3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14739303
12471095
16281057
|
IRAK4
|
SOCS3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
11274345
11964313
12620219
12682231
12907458
14607900
14660645
15749884
15749903
16127449
16243976
16413922
16713974
16878026
17404308
17485448
17704786
18633355
20547845
21372296
21826665
23508573
23681101
23811849
9743347
|
JAK1
|
SOCS3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
25682267
10950967
16459330
10707961
10373548
|
IFNA6
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
TRAF2
|
FADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
74.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11875494
12215447
12646658
12702723
12724420
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21826665
22427918
22955274
23010170
23069999
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
8910423
9488730
9759866
|
FADD
|
TICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
22421964
21737330
15814722
19278658
12620240
20308068
12181749
|
FADD
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
52.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
TRAF2
|
FADD
|
â—¼ SHARES_COMPLEX
|
|
|
74.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11875494
12215447
12646658
12702723
12724420
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21826665
22427918
22955274
23010170
23069999
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
8910423
9488730
9759866
|
FADD
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
52.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
TRAF2
|
FADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
74.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
1134007
11438547
11460167
11583996
11875494
12215447
12646658
12702723
12724420
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
15760909
16406523
16498403
16713974
16940415
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19597341
19632174
19838173
20038811
20184663
20435894
20452955
20531300
21133840
21232017
21411734
21826665
22427918
22955274
23010170
23069999
23170255
23377657
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
27984721
28574505
8910423
9488730
9759866
|
FADD
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
FAS
|
FADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
22864571
8521815
11717445
21713032
16762833
23606538
8967952
20935634
7538907
21803845
9325248
19118384
12721308
21959933
18328427
16189514
25563855
10196099
17159907
27321185
26186194
25241761
9880544
16498403
21625644
9082980
12107169
15659383
15993755
21382479
7536190
11464215
26942442
11035039
15725726
16410793
|
AKT1
|
TSC2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10722653
10949026
11715018
11756412
11923280
15169778
15808505
16697215
17052453
17680028
18372248
18570873
18636226
20138985
20214616
20398329
20832730
9812896
|
TSC2
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
12906785
16636147
17680028
19022819
20146692
|
AKT1
|
TSC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
75.0
|
1.0
|
Omnipath
|
16873412
12820960
17018601
11756412
32308763
11923280
16697215
19690332
21893193
20398329
18372248
21177249
12438239
18466115
15808505
29042482
20138985
15342917
17597835
20214616
12271141
16702951
20837138
17570479
26844273
15169778
17386266
10949026
16288292
24590173
11715018
15661536
18636226
18411301
20028854
9812896
16636147
20169078
17680028
12172553
19664994
18707149
10722653
12150915
18570873
20832730
12364343
17052453
18283331
21666717
27451907
|
TSC2
|
RHEB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
15340059
15854902
23331499
16636147
12869586
17680028
21071413
20146692
12771962
20226003
12906785
12842888
|
MAP3K7
|
TICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
15327770
19675569
16115877
10882101
|
TRAF2
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
57.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11280761
11438547
11460167
11875494
12646658
12811837
1431106
14607933
14625680
14660645
14730360
15099563
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26972597
28574505
8910423
9488730
|
IKBKB
|
MAP3K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
20300203
9744859
17047224
11460167
17496917
14514672
|
TRAF2
|
MAP3K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
12547194
20038579
14633987
14743216
17384642
|
MAP3K7
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
24911653
11129660
25195736
16006187
16260493
15502405
14530355
10779355
28159912
10094049
10837071
15836773
25659581
10195894
9689078
17363973
10807933
15214841
16186825
16493424
10022904
18316610
10187861
12547194
33895773
28475177
16301747
15691841
15620648
15327770
29748387
19632174
11460167
17965022
|
TRAF2
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
TRAF2
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
TRAF2
|
FAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
36.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
15592525
15760909
16406523
16498403
16940415
17462996
18641653
19392652
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22427918
23010170
23069999
23377657
23850759
24378531
26587781
26653790
26972597
27984721
28574505
9488730
9759866
|
TRAF2
|
IKBKB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
11274345
12847084
15592525
17462996
18641653
19392652
19509052
21133840
21232017
23430059
23850759
24378531
26587781
|
NFKB1
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15723831
15041463
19392652
18990758
|
RELA
|
TRAF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15041463
19392652
21573233
15723831
9733516
|
TRAF2
|
BIRC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
36.0
|
1.0
|
Omnipath
|
18997792
8643514
11907583
16713569
18621737
18997794
21988832
18606850
9384571
16891304
10753917
18981220
24464131
20562859
25241761
23543740
20385093
21331077
23007157
16282325
23524849
8548810
19815541
|
TRAF2
|
TICAM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
19795416
14982987
20418377
20047764
|
TRAF2
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
27387502
15725726
12547194
11359906
25241761
20449947
16713569
18362886
23007157
10795740
21119000
19150425
|
IFNB1
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
15312780
9121453
10395669
9334213
15778442
12842042
17969444
|
IFNAR1
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15312780
8943354
18508557
15449939
17969444
16171819
|
IFNG
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
16467876
7617032
7673114
12438563
10986460
7615558
1396683
8550631
|
JAK1
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
JAK1
|
TYK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
85.0
|
1.0
|
ACSN
|
10433356
10485906
10542212
10623821
11160275
11207245
11306493
11371360
11698286
11867689
11870632
11875494
11964292
12223527
12401408
12496409
12754507
12811837
12818165
1439146
14607900
14610620
14657224
14764699
15099563
15282297
15356132
15573129
15579430
15864272
16200688
16243976
16413922
16424049
16713974
17404308
17485448
17513775
18209571
18250477
1825141
18451175
18555777
18555778
19581928
19833085
20138012
20184663
20406969
20510870
20856220
21097505
21115385
21191065
21220452
21469115
21840487
21930765
21930769
22595692
23034983
23124025
23390297
23567181
24011634
24030977
24091328
24346288
24418198
25002027
25582338
26201938
26268945
26755705
27216177
27557510
2965306
7512720
7521688
7543512
7590867
8837607
9535722
9834059
9845545
|
JAK1
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
JAK1
|
IFNG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
JAK1
|
IFNGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
JAK1
|
IFNG
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
JAK1
|
IFNAR1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
JAK1
|
TYK2
|
â—¼ SHARES_COMPLEX
|
|
|
85.0
|
1.0
|
ACSN
|
10433356
10485906
10542212
10623821
11160275
11207245
11306493
11371360
11698286
11867689
11870632
11875494
11964292
12223527
12401408
12496409
12754507
12811837
12818165
1439146
14607900
14610620
14657224
14764699
15099563
15282297
15356132
15573129
15579430
15864272
16200688
16243976
16413922
16424049
16713974
17404308
17485448
17513775
18209571
18250477
1825141
18451175
18555777
18555778
19581928
19833085
20138012
20184663
20406969
20510870
20856220
21097505
21115385
21191065
21220452
21469115
21840487
21930765
21930769
22595692
23034983
23124025
23390297
23567181
24011634
24030977
24091328
24346288
24418198
25002027
25582338
26201938
26268945
26755705
27216177
27557510
2965306
7512720
7521688
7543512
7590867
8837607
9535722
9834059
9845545
|
JAK1
|
IFNGR1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
JAK1
|
IFNGR2
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNAR1
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
8943354
18508557
8232552
17351669
8524272
7526154
9334213
23331499
10542297
11694501
10982844
15449939
15312780
8702790
8621447
17969444
8605876
10022928
15120645
16171819
29145629
8197134
16987978
24243840
|
JAK1
|
TYK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702790
19901323
7504784
7589562
15659558
30029643
|
JAK1
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9774657
15021914
|
JAK1
|
STAT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
29145629
23331499
10542297
24243840
8197134
10022928
7532278
18508557
16987978
8232552
9020188
12040185
8605876
18988627
10982844
25386349
|
JAK1
|
IFNGR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12133952
8232552
8550631
8156998
7796299
7615558
8649432
19041276
|
IFNG
|
IFNGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNGR1
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
42.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
22003200
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR1
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNGR1
|
IFNGR2
|
â—¼ SHARES_COMPLEX
|
|
|
42.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
22003200
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
16110316
12915721
12438563
7514165
15530433
23331499
16237089
23898330
9111318
15143187
16467876
10986460
18988627
1396683
8550631
20304997
11250200
10860730
12165521
29145629
10811850
7617032
18591661
8631301
7615558
7510216
7673114
|
IFNG
|
IFNGR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
IFNG
|
IFNGR2
|
â—¼ SHARES_COMPLEX
|
|
|
41.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11867689
11870632
11964313
12413632
12811837
12818165
14607900
14610620
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
17683974
1825141
18272812
19833085
20038811
20406969
20819927
21149606
21411734
21840487
24091328
24658051
26755705
27216177
2965306
6425450
7512720
7521688
9834059
9864217
|
TICAM1
|
IFNG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
ACSN
|
11672593
11964313
12032143
12811837
15644117
16306937
16917499
17114424
20154735
20547845
23508573
|
IFNG
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
48.0
|
1.0
|
ACSN
|
10485906
10679398
11489965
11579131
11777960
11870632
11964313
12133954
12413632
12759422
12818165
14607900
14668329
15079071
15536066
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17145890
17404308
17550372
17559085
1825141
18272812
19171876
19833085
20038811
20138012
20819927
21149606
21224476
21411734
23430059
24658051
26755705
2965306
6425450
8383323
8580069
8641346
9743347
9834059
9864217
|
NFKB1
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12759422
21642544
21243522
9374532
10227974
16481345
17556653
19732956
21224476
14662860
12757742
18690006
17407192
|
RELA
|
IFNG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
17035338
12759422
12105194
21243522
9374532
10227974
20643337
19929594
19732956
21224476
23195252
23667107
12842891
14662860
12757742
18690006
17407192
10075983
|
IFNG
|
IFNGR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
12915721
7673114
7514165
12438563
15530433
23331499
16237089
9111318
15143187
16467876
10986460
18988627
1396683
8550631
29145629
10811850
7617032
18591661
8631301
7615558
7510216
20304997
|
IFNB1
|
TYK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15312780
8943354
18508557
15449939
17969444
16171819
|
TYK2
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
TYK2
|
IFNAR1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
IL1B
|
TYK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10198225
7528775
9038232
8943050
9454765
7594594
|
TYK2
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
9677371
8524272
24704786
14647450
7526154
16551269
21949722
23223197
16189514
9121453
8702790
9461596
8605876
7559568
12220192
21994561
15337770
8700538
20937132
8628273
18166147
95059042
9733772
10523853
|
TYK2
|
STAT2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
8943354
18508557
8232552
17351669
12040185
7526154
9334213
23331499
10542297
24243840
23223197
11694501
15449939
18988627
15312780
8702790
8621447
17969444
8605876
10022928
32953130
21994561
1638633
16171819
29145629
18989459
34521819
8197134
16987978
10982844
8605877
|
RELA
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
12820969
11478739
17510282
19786024
12050170
21138578
12122011
19828633
18367595
22030901
18502824
16707500
10926836
11413310
20663893
22388040
15144466
9120310
12603855
26096887
11259372
21189258
12388374
15972972
11389171
25523420
18525004
|
NFKB1
|
CCL5
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
12820969
11413310
11478739
12122011
17065335
17510282
11700023
15144466
19786024
16707500
21189258
12388374
15972972
9120310
11389171
12050170
11259372
|
AKT1
|
RHEB
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
17517883
17277771
18372248
12524439
17386266
|
NFKB1
|
FAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11473033
16317104
10022897
16784892
7528667
19628709
9733827
10871852
|
EIF2S1
|
EIF2B2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
12601012
12667446
16246152
23850759
|
EIF2S1
|
EIF2B2
|
â—¼ SHARES_COMPLEX
|
|
|
4.0
|
1.0
|
ACSN
|
12601012
12667446
16246152
23850759
|
EIF2AK2
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
85.0
|
1.0
|
Omnipath
|
28167698
11432733
28781602
20685959
9335428
10504407
3352609
24178712
25687824
17290288
24706853
16288713
19043413
19259124
23399035
21738672
8626809
9431994
21899699
11985496
2912723
23259068
28670265
19364808
2116318
9819435
23706307
8099443
8096514
31226023
18096616
15550948
8099444
17372663
24335187
11337501
9930704
21377708
23056444
21418572
18971339
16179258
20149255
19583950
28623239
10542257
21368187
1677563
22174864
11452027
24909749
20040105
12737801
16179259
16289913
25521494
|
EIF2AK1
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
28781602
10504407
3352609
11041858
24706853
16288713
28670265
2116318
9819435
8099443
15550948
11337501
9930704
16179258
19583950
10542257
10563826
1677563
24714526
|
PPP1CA
|
EIF2S1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21622569
9694816
9023344
12941928
|
NFKB1
|
RELA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
IKBKB
|
RELA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
RELA
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
27.0
|
1.0
|
Omnipath
|
12820969
14688340
20221401
11058167
10657616
10940886
19122653
18690006
11792125
19624579
17982049
9464836
17924060
7565674
14976188
15251981
12077291
17579043
24012417
19299558
16166378
12517966
17635610
24184907
15270850
20876114
9808189
|
RELA
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20186924
18031796
20649564
|
RELA
|
BIRC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
15231833
15050749
19343319
17673602
18226221
23250755
17000776
11880364
21279667
21765477
10733571
18566231
12010810
15723831
10823821
11297551
16291753
|
RELA
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
26596471
27338466
11114294
8413223
20975042
17707233
23383347
11058167
12686724
16433741
23667107
15382119
19122653
24009751
27211851
18566416
15292915
20617571
23056550
12517972
18285351
19843519
22267743
15812237
25161822
22388040
8021507
9878621
14960579
10963848
23195252
11395507
27534992
9058643
15543947
19846753
20696864
8679226
24908318
28389361
27371733
15972680
20336759
10080875
17082635
|
RELA
|
NFKB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16778171
20427719
23362108
16513645
1740105
20596645
16513841
19469019
8454856
21420936
16135789
9417120
|
RELA
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
23932714
15955070
22547704
19570999
10074115
21209118
17079305
7799921
17496231
15699120
12077266
8035474
17785777
12005436
24185615
10848607
16125763
9446577
20855868
24656046
23857586
|
NFKB1
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
88.0
|
1.0
|
Omnipath
|
17145710
16209943
25609649
8428580
12947093
16970925
17072323
2050119
15657065
21270162
11976329
16793322
21544861
22261743
8657102
9824778
11880271
9450761
17962807
21988832
25355951
9722548
18215660
14743216
15799966
10799898
16105840
15218526
8798655
14690596
22139845
22808155
11571291
17072327
16740634
10498867
8255759
8246997
15214841
16846590
15371334
16285893
17072322
17855547
18321863
16493424
7479976
15145317
17561400
20110362
9426183
23687337
12414801
11970949
20154269
20237821
24175631
24634218
34100597
14645533
17982102
21763497
16204234
9437432
20547752
15818410
7628694
|
IKBKB
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
135.0
|
1.0
|
Omnipath
|
15280197
17785205
27329558
22110409
22753932
22205033
21765477
15611068
18519641
15858576
25241761
33579825
23536830
28122346
19393267
34556881
24442433
14560022
15192014
21242976
16840782
19609947
33789981
10521409
26826124
21492457
19110719
23303310
16105840
22212641
26587973
34219129
15210811
16046471
11359840
27626700
15128824
28416608
17178723
21674813
17362989
28737909
19377466
15980040
16407239
15849198
20507904
26082493
15557193
34082140
21798539
26267322
29363544
12767944
20224721
26307684
12842894
17108032
26170389
24336331
27315556
31980577
11259436
34380537
20872791
21674474
15465828
15994321
17548605
26603838
16148147
25136068
33914760
26569329
22234699
17012367
14636585
22039465
32123095
15212693
27466442
33883226
15611276
22081069
19197368
17070014
20051109
26693062
14963024
33971703
28381553
33459422
27244888
18544167
18922932
20188669
15485852
20696864
22689577
17982102
20410276
15489227
|
IL1B
|
RELA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25606026
26999213
22240205
23666959
19197368
25306394
24009751
|
SRC
|
PIK3R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
21780115
15032589
11526404
23109003
22880054
10488096
|
SRC
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
17145710
12645577
12707358
15456896
|
SRC
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
11445557
25241761
23242524
18283331
12600984
|
IFNB1
|
STAT2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
15312780
9121453
10395669
9334213
15778442
12842042
17969444
|
STAT2
|
IRF9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
29145629
7537377
9242679
23331499
8621447
24065129
17923090
21903422
15978943
8943351
12590259
17351669
21178011
21268015
|
NFKB1
|
IL1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8413223
17707233
11058167
12686724
16433741
18285351
8021507
9878621
14960579
10963848
9058643
15543947
20696864
8679226
11035101
15972680
20336759
18772363
10080875
17082635
|
PPP1CA
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20186153
14633703
|
AKT1
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15184909
25241761
22689577
15856005
10485711
17660512
|
AKT1
|
ALYREF
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18562279
|
IKBKB
|
NFKB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
9315679
9914500
9721103
10593898
9135156
|
NFKB1
|
BIRC3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
21725609
23178297
23572150
9294162
9733516
|
NFKB1
|
BIRC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15231833
15050749
19343319
17673602
17000776
11880364
10733571
9733516
18566231
12010810
15723831
10823821
11297551
|
NFKB1
|
IL12B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
14688340
11058167
10657616
10940886
18690006
11792125
17982049
9464836
17924060
7565674
14976188
9234715
12077291
9497375
17579043
19299558
22427889
16166378
15270850
9808189
|
NFKB1
|
IFNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
15955070
17079305
7799921
17496231
15699120
10074115
20855868
24656046
10848607
12077266
8035474
17785777
20048166
21209118
16125763
12005436
22427889
21343618
|
IKBKB
|
NFKB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
57.0
|
1.0
|
Omnipath
|
31598684
11976329
16713569
10469655
29485707
26999213
12842894
10835356
27187478
27402796
18782567
27554194
12482991
25241761
10022904
15199157
19519322
15489227
19250910
15212693
11158290
11297557
|
EIF2B4
|
EIF2B2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
25910212
10805739
31515488
16189514
32296183
9446619
|
IKBKB
|
TICAM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15064760
15814722
16115877
16603398
16547522
|
MAVS
|
IKBKB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17145710
16177806
16153868
21903422
17468758
18207245
|
IFNB1
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15312780
8943354
18508557
15449939
17969444
16171819
|
IFNB1
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
8181059
1834641
10049744
7592797
7623815
11278538
18988627
29311663
112785381834641
|
IFNA7
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA10
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA2
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7592797
9334213
1834641
|
IFNA17
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7623815
21856167
|
IFNA8
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7592797
21856167
|
IFNA5
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
HLA-DRA
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DRA
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
PIK3R3
|
PIK3CB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8596638
22402981
11733063
25814554
|
IFIH1
|
MAVS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19416887
22301138
17600090
17020950
19052324
21903422
16410796
16785313
16713980
23499489
16127453
33372174
16125763
|
MAVS
|
STING1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
19416887
18818105
20080758
20019757
22312431
22844514
23542348
18724357
24622840
22911572
|
HLA-DQA1
|
HLA-DMA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA1
|
HLA-DMB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|
HLA-DQA1
|
HLA-DOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
9606180
7481823
9075930
9311912
7667286
8046351
10631952
|