Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
FXR1 TRIOBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 TRIOBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
VIM IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TSC1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
VIM TRIOBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
TSC1 TRIOBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GSK3B TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15972957 16959574
GNAQ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20399743
HECTD3 TRIOBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18194665
FGFR2 FGFR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EGFR NTRK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
FXR1 FXR2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
VIM CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
FXR2 FXR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 7489725 21653829 8668200 24778252 33961781 24981860 29395067
PPP1R12A PLK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 18477460 22641346 22365832
PLK1 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 18477460 22641346 22365832
VIM GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A PCNA â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
PPP1CB PPP1R12A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
GSK3B CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 22154077 28916781 12058028 11779850 17570479 20519948 15212693 17283049 19440234
CDKN1A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 23443559 25411249 20606006 8868473 15576034 16474839 25416956 20605778 16510448 18703516 23139781 11302688 11254741 26272819 16616141 21988832 11313979 7780738 17588519 12964161 25502805 10022118 8861913 16189514 26496610 16082198 8861969 17129767 18263614 26186194 22383522 22911014 7915843 7911228 27107012 23223023 17115032 32296183 19895794 18794347 19704162 10873631 9546435 8662825 31515488 21415862 9545252 11350925 12930846
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1382070 31980649 24658140 12560083 9230083 15212693 10377409 15647376
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
NUAK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17739896 24171924 22516431 18088087 19367720 19690332 20354225 19413330 18669648 29106388
PLK1 TRIOBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22820163 24692559
PLK1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 28390425 27603133 24196446 18056432 16260496 28953239
FGFR1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11019781 12601080
TSC1 RAC1 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11955434 12829230 12906785 15611338 15851026 15967165 16636147 17680028 18974095 19022819 20146692
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153