ACKR3
|
CXCL12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9618518
16107333
|
IL1R2
|
IL1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16971486
0603545103
|
IL1A
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16971486
0603545103
|
IL1A
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2946959
8327496
|
APP
|
TNF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TNF
|
LTBR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8171323
24636534
|
CXCR6
|
CXCL16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11060282
9166430
|
CCL21
|
CCR7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
8383238
7851893
|
BMP10
|
ACVRL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17068149
17311849
|
IL1R1
|
IL1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221365
9062193
|
APP
|
NGF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
NGF
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
IL4R
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10219247
5211389
|
IL2RA
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
IL2RG
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
IL2RA
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
IL2RB
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15178252
16477002
|
EBI3
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
IL27RA
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24743305
24572363
|
IFNE
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22410872
32196115
|
IL36G
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17208301
23331499
|
IL2RA
|
IL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0607058103
17032757
|
IL10RB
|
IFNL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
IL10RB
|
IFNL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
OSM
|
IL6R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
16204061
21840487
|
IL33
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18450470
19836339
|
TNFRSF21
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14585074
9714541
|
CD70
|
CD27
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17237405
19062317
|
IL36G
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17208301
23331499
|
IFNE
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22410872
32196115
|
IL22
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17208301
23331499
|
ACVR2B
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
CXCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22633458
15178708
|
ACVR2B
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
ACVR2A
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9748228
8612709
|
BMPR1B
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1B
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
BMPR1A
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10712517
|
ACVR2B
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
INHBE
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22710174
|
BMPR1A
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7644468
7791754
|
INHA
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
29747587
32196115
|
ACVR2B
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
IL12A
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
IL6ST
|
CTF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2779549
15519241
|
IL6ST
|
IL11RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
7957045
8637716
|
IL6ST
|
EBI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22306691
12829785
|
IL6ST
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12707266
7852997
|
IFNLR1
|
IFNL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
IFNLR1
|
IFNL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
15166220
19457860
|
EDA
|
EDA2R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14656435
10484778
|
EPOR
|
EPO
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
IL1RN
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
1828071
2139180
|
IL23A
|
IL12B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
IL12A
|
IL27RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
24743305
24572363
|
CCL1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11470772
10910894
|
CCL18
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23951310
32103204
|
CCR3
|
CCL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12554737
9276730
|
CCR6
|
CCL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9169459
12149255
|
BMP6
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16446785
|
PF4V1
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22633458
28859966
|
IL24
|
IFNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18511292
|
CCL25
|
CCR9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10229797
10640743
|
IL17C
|
IL17RE
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21993848
21993849
|
ACVR1
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
ACKR3
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
ACVR1
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
CSF2
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11468284
9187659
|
IFNA4
|
IFNA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IFNA4
|
IFNA8
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ACVRL1
|
BMP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
GDF11
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
IFNA5
|
IFNA6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
CCR5
|
CCL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9334377
10477718
10498628
8663314
23597562
12427015
9468473
|
CSF3
|
CSF3R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
16492764
10364174
|
IFNA2
|
IFNA5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IL9R
|
EDA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
BMPR2
|
BMP6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11401330
10504300
|
IFNA5
|
IFNA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IFNL3
|
IL10RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
LTB
|
LTBR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
IL1B
|
IL1R2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
TGFB2
|
TGFB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
27684187
11483955
33961781
11157754
|
CD70
|
CD27
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
7479974
8186199
9862673
9767422
21917027
15723067
8120384
33961781
26186194
8580829
|
LTA
|
LTBR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
IL12B
|
IL23R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
IFNL3
|
IFNLR1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
12469119
|
IL22RA1
|
IL22
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
18675809
6693914
|
LTA
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
CCR3
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8642344
10733106
|
BMP7
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8006002
18070108
16189514
|
CCR4
|
CCL22
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9743322
9933589
9430724
|
CCR4
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8573157
12270118
|
IL2RG
|
IL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
8266077
9010926
11858939
8128231
9371812
|
IL2RA
|
IL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
17032757
16477002
1993646
|
CCL23
|
CCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9886417
9558365
10660125
|
IL6ST
|
OSM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
860.0
|
0.86
|
STRING
|
36370105
|
ACVR2B
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
ACVR2B
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
CCL5
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
LIFR
|
OSM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CCR1
|
CCL7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8530354
7545673
9336350
|
CCR3
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
10733106
8642344
7622448
9289016
|
CCR1
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11449371
12270118
8530354
7545673
14637022
11116158
7622448
9115216
9289016
10910894
9336350
|
IL16
|
CD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
7910967
16189514
1851800
|
EDAR
|
EDA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11309369
11035039
|
FAS
|
FASLG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
IFNA14
|
IFNA6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
IL20RB
|
IL22RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
BMPR2
|
BMP7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7644468
7791754
|
IL1R1
|
IL1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7878046
9062193
|
IL15
|
IL2RG
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
8178155
10903799
8568232
9371812
|
IL2RG
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
11886175
10903799
8006584
20816854
|
CD4
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10816381
15660419
14592831
|
GDF5
|
BMPR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19229295
9525338
|
BMP4
|
BMPR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
TGFBR2
|
TGFB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
8044119
21054789
|
IL3RA
|
IL3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9278420
7957082
8649415
|
CCR5
|
CD4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10816381
30542158
15660419
|
CSF1R
|
IL34
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22483114
23478061
|
BMPR2
|
ACVR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
7890683
28514442
7791754
|
ACVR2A
|
INHBA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
BMPR2
|
BMP4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28126904
12045205
7673243
7644468
8702914
|
IL15
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
BMPR1A
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ACVR2A
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
IL1RN
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
2876877
|
CXCR1
|
CXCL6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
1840701
3260265
9164944
|
CCL16
|
CCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCL16
|
CCR8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
7679328
9207005
8048929
|
CCR5
|
CCL5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11449371
10477718
10488147
9334377
8663314
14637022
9207005
11116158
9289016
|
IL2RG
|
IL21R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11418623
11016959
12093291
|
IL15
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
25416956
23104097
10903799
9176231
8026467
|
IL2
|
IL2RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11035066
16477002
8049354
8006584
22446627
|
IL15RA
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17709786
15265897
7641685
|
IL12A
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
IL12B
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18389480
7638186
7528775
|
IL6ST
|
IL12RB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
24743305
22306691
12829785
|
IFNK
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17208301
23331499
22410872
|
IL10RB
|
IFNL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12469119
21716315
23291588
|
IL10RB
|
IFNLR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12469119
21716315
23291588
|
IL10RB
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12483210
23331499
12974481
|
CSF1R
|
CSF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26235028
2408759
22483114
8355686
22153499
22902366
|
CSF1
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16492764
23331499
|
CSF1
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
CCR5
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12429730
15660419
18632580
|
OSM
|
LIFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
8119965
2779549
12811586
|
LIFR
|
CTF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11834704
7862649
7738033
|
LTB
|
CD40
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7916655
|
CSF3
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
10572088
|
IL37
|
IL18R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12096920
25654981
|
IFNK
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17208301
23331499
22410872
|
IL24
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12351624
22802649
11706020
|
IL20RB
|
IL20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11163236
22802649
12351624
|
AMHR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
14746809
16446785
|
INHBC
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12651901
|
GDF11
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12414726
|
ACVR2A
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12682303
9032295
8612709
|
INHBE
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22710174
|
ACVR2B
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
17295905
16446785
|
IL6ST
|
IL27RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14764690
27119567
24771852
|
IL6ST
|
IL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14764690
27119567
24771852
|
EBI3
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22306691
28280243
|
CCR3
|
CCL11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8676064
10733106
9169459
9712872
9207005
8642344
25450766
8609214
23597562
|
EPOR
|
EPO
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
9030560
29997244
9808045
17327410
9774108
26481148
15358619
10318834
8662939
|
TNFRSF13B
|
TNFRSF17
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
11571266
10398604
10359578
|
IL23A
|
IL12B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29997244
12023369
11114383
18680750
|
IL12B
|
IL12A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10899108
10779781
7527811
|
IL17RA
|
IL17C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23834281
21993849
21993848
|
IL12A
|
EBI3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22487722
18033300
9342359
|
IL24
|
IL20RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
12351624
22802649
11706020
|
CCL13
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10699158
23846739
|
CCR10
|
CCL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
CCR10
|
CCL28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
10781587
10725696
10725697
|
INHBC
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12651901
|
IL27RA
|
IL27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14764690
27119567
24771852
|
IL17RE
|
IL17C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
23834281
21993849
21993848
|
BMPR1B
|
GDF5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
IL6R
|
IL6ST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
SGTA
|
TNFRSF10C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HuRI
|
32296183
|
EPO
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
SGTA
|
TNFRSF21
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
GDF2
|
ACVRL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
17068149
|
IL34
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
24890514
|
TNFRSF1A
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
BMP4
|
BMPR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
LEPR
|
LEP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
22405007
9786864
33961781
8608603
|
IL23A
|
IL23R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
IL17A
|
IL17RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
924.0
|
0.92
|
STRING
|
36370105
|
IFNAR2
|
IFNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
IL20RA
|
IL20RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
IL20
|
IL20RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
PRL
|
PRLR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
931.0
|
0.93
|
STRING
|
36370105
|
CD40
|
CD40LG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL15RA
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL15RA
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CSF3
|
CSF3R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IFNAR1
|
IFNW1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL20
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IFNL1
|
IFNLR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
GH1
|
PRLR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
IL1R1
|
IL1RN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
IL1R2
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
ACVR2B
|
GDF11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
IL1B
|
IL1R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
IL2RB
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
CCL20
|
CCR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
10488147
10498628
9169459
9223454
9294137
|
ACVR2A
|
BMP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
ACVRL1
|
GDF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
IL1RAP
|
IL1RL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
IL1RL1
|
IL33
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
IFNAR1
|
IFNAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
IL2RG
|
IL4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
18243101
8266078
|
IL2RG
|
IL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
16477002
8049354
11418623
8006584
10662798
22446627
|
LTA
|
LTB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
IL12A
|
IL12B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
ACVR2B
|
INHBA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
953.0
|
0.95
|
STRING
|
36370105
|
CSH1
|
CSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
LIF
|
LIFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
8999038
8662595
16051226
9852103
12601009
|
PRL
|
PRLR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10966654
9626554
22325776
23048206
7984244
|
CRLF2
|
IL7R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
964.0
|
0.96
|
STRING
|
36370105
|
IL6ST
|
LIF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
IFNA2
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
GH1
|
GHR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CCL5
|
CCR5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IFNA2
|
IFNAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL1B
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL7
|
IL7R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
IL12B
|
IL23A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
CCL11
|
CCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
IL22
|
IL22RA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
CCR5
|
CD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
TGFBR1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
CSF1R
|
IL34
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
TNF
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
LTA
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CXCL12
|
ACKR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23396314
20956518
24218476
16107333
22633458
20161793
|
CXCL11
|
ACKR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
29386406
29180449
27875312
24218476
22633458
16940167
20161793
|
CXCL12
|
CXCR4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
15261139
15882617
17035340
20535745
20644254
21521526
22025564
23034983
23402812
23567181
24277834
|
CXCL12
|
CXCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
24023874
10233851
10699158
11859124
22633458
18648536
18448868
8752280
30476826
12714578
16725153
9712844
8752281
9551924
21757744
19837984
25495026
26582643
16626895
|
CXCL12
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9660793
|
IL15
|
IL1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL1A
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
25241761
16971486
7878046
1833184
9862719
23395675
78780467878046
|
IL1A
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
23331499
29469592946959
8142597
19479203
7692435
9565970
7775431
2946959
17507369
7964161
|
IL1A
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9820540
9862719
7775431
17507369
|
TNF
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
TNFRSF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
TRADD
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
IL15
|
TNF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
TNF
|
LIF
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
TNF
|
TRADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
CXCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10925299
11112697
11438547
11875494
12646658
12811837
1431106
14607933
14625680
15099563
15699106
16713974
17916596
18633355
19411070
20038811
20184663
20435894
21133840
21411734
21826665
22595692
22955274
23170255
23430059
23508573
23510023
23567181
23769623
24092389
24378531
26201938
8910423
|
IL6R
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
35.0
|
1.0
|
ACSN
|
11306493
11867689
12754507
1439146
14610620
15099563
15356132
15573129
18209571
18555777
18555778
19581928
19833085
20138012
20406969
21115385
21840487
23034983
23567181
24011634
24091328
24346288
24418198
25002027
25582338
26201938
26268945
27216177
27557510
7512720
7521688
7543512
7590867
8837607
9845545
|
TNF
|
TNFRSF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
98.0
|
1.0
|
Omnipath
|
17145710
19084540
8288897
11448951
23746843
22801493
14732063
2848815
9568681
2158863
8182064
9488135
23070005
20080539
11239407
26670046
14743216
21724995
21133840
24070898
25911380
7852363
2170974
17151142
26186194
27560715
25241761
23032187
24726327
20103630
8805640
11502070
19442713
3034874
23955153
18067990
22099304
15485837
22675546
12753742
1310388
12887920
19287455
10634209
2170559
1331108
24980434
22028622
|
TNF
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
12887920
19287455
15485837
32196115
|
TNF
|
TNFRSF1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
17145710
19084540
11448951
12040173
8590321
14732063
7930591
9568681
2158863
8182064
9488135
11239407
14743216
24070898
7966397
7852363
17151142
8805640
7664431
15485837
2172983
1310388
15450251
1655744
19287455
1328224
|
TNF
|
TNFRSF21
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9714541
|
TRADD
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
LTA
|
TNFRSF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8171323
8182064
8288897
2170974
16189514
8387891
7995952
12387745
1310388
|
TNFRSF1A
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
17145710
8565075
8943045
11934887
8612133
9915703
11684708
8621670
9430227
19641494
27552911
16611992
21760970
11821416
10187805
21724995
12721308
21741934
21232017
10795740
21119000
15310755
11502070
15115707
23955153
18776134
18939944
9916731
9129204
9082980
15485837
15173123
22297296
15357952
24130170
12887920
10634209
24758719
19524513
15465831
7758105
11035039
8791485
15725726
|
LTA
|
TNFRSF1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8182064
9552007
2160731
7995952
1328224
8123048
1310388
|
CCL7
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
14991608
12381680
9115216
10699158
11994538
7545673
22633458
9336350
8530354
|
CCL7
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8642344
10733106
10699158
22633458
|
CCL7
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
10477718
16298345
10699158
22633458
10477710
|
CCL7
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10706668
9364936
|
CCL7
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
9660793
|
CXCL8
|
CXCR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL8
|
CXCR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
15079071
17533374
17784835
17916596
18555778
18633355
18980965
21328342
21847358
24406209
25922287
26201938
26548401
27557510
|
CXCL6
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8702798
10699158
9485196
16189514
9692902
22633458
12964882
10593335
|
CXCL5
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8702798
10699158
16189514
9692902
12964882
9485196
|
PPBP
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702798
1427896
8195702
8137938
24335961
16189514
22633458
|
CXCL8
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
8702798
8137938
9195914
10699158
1840701
12628493
10188995
15946947
22262769
8550564
9553055
1379593
8662882
8245475
10368283
9485196
8940121
15282370
11350788
9725262
10206993
|
CXCL1
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8702798
9195914
10699158
16189514
1379593
12964882
|
CXCL3
|
CXCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
129648828702798
8702798
16189514
12964882
|
CSF2
|
CXCL1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
CSH1
|
PRLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17145710
10966654
|
SGTA
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
23533635
28104892
23129660
23246001
25179605
|
BMP7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9748228
7790373
12667445
|
BMP7
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11282024
8006002
31619522
122976748006002
16189514
12297674
|
BMP7
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
106311828605097
8605097
10631182
|
BMP7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
18342887
16446785
7791754
7644468
|
BMP7
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9748228
23331499
16446785
|
BMP7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
16189514
7791754
12297674
8605097
|
CXCL16
|
CXCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
11017100
14625285
11290797
22633458
|
CCL21
|
CCR7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11970971
10488147
9507024
10699158
16713569
22633458
22221265
9585422
|
CCL21
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26888559
11907075
|
BMP10
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17068149
|
BMP10
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16049014
|
BMP10
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15621726
16049014
|
BMP10
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
30246251
30246252
27252362
31127068
|
BMP10
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15621726
31127068
16049014
|
IFNA6
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA6
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
CCL4
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
7594543
12381680
10699158
7545673
10910894
8530354
|
CCL4
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7622448
|
CCL4
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10699158
9521068
|
CCL4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10498628
16298345
8663314
10477718
9468473
20219869
23597562
10699158
9334377
9790730
16467191
22633458
12427015
12964882
|
IFNA14
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA14
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
CCL22
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9933589
9430724
29637711
10699158
22633458
9743322
|
CCL17
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10498628
10488147
9169459
9430724
29637711
10699158
9169480
10540332
22633458
|
CCL5
|
CCR4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8573157
12270118
|
CCL16
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
11470772
|
CCL16
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11470772
22633458
10910894
|
CCL16
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
10910894
|
CD40LG
|
CD40
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD40
|
â—¼ PROTEIN_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD40LG
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
11581322
15034038
17200410
17371980
23125331
8760829
|
CD40LG
|
CD40
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
1280226
1374165
19426221
7516405
11163401
7543281
12324477
10647992
17183360
|
TGFB1
|
TGFBR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
TGFBR1
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFBR2
|
CCL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
TGFBR2
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
IL18
|
TGFBR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
IL15
|
TGFBR2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
TGFB2
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8106553
1310899
23331499
21071413
12729750
16446785
12809600
11157754
|
TGFB1
|
TGFBR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
122.0
|
1.0
|
Omnipath
|
1310899
22874531
8047140
11279127
22710166
7878020
16424049
17673906
24132110
18922473
22943793
12729750
16446785
20519943
7706250
15761153
7594497
15548370
15761148
15265520
19010789
26194464
7852346
12717440
17768418
19050695
11133108
14557817
11278410
19920116
22949611
22703233
23331499
23070005
20060931
17070508
21614932
1333888
10716993
16572188
20860622
11323414
21900405
12724770
8106553
23034983
26192618
2871107
12809600
11382746
21372296
20538542
16200688
11792802
26201938
24403530
15099563
11013220
17979848
21054789
23784029
15003992
20644162
8515656
7935686
11157754
20856203
18382895
15282297
18855897
9865696
21441952
10678166
16127449
21041659
10026191
22315516
12767520
17404308
19732719
20616810
21071413
17934056
12738796
18423981
21098712
19747910
9311995
15034927
11274345
12154066
18758450
24336330
21278795
26966341
9261125
16474430
15653932
18490733
8242742
19038247
19109155
|
TGFBR2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
48.0
|
1.0
|
Omnipath
|
7774578
9463378
19556242
8047140
23868260
18243111
7890683
10026191
23331499
8576253
21071413
7878020
21791611
10716993
18988627
11278251
19758997
25825445
22802914
16446785
11483955
8947046
11323414
11124802
15221015
11102446
11387212
12809600
7566156
26194464
|
IL1R1
|
IL1RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
14660645
16878026
17704786
17942936
18977329
19104081
19161412
23202296
23681101
23811849
24727385
|
IL1R1
|
IL1RAP
|
â—¼ PROTEIN_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11274345
12620219
12682231
14660645
16878026
17704786
17942936
18977329
19104081
19161412
23202296
23681101
23811849
24727385
|
IL1RAP
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15044087
23331499
15866876
9430229
10854325
11756486
9371760
7775431
12530978
17507369
|
IL1B
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
17145710
23331499
8142597
9062193
7878046
9820540
7775431
2946959
24166242
9625767
|
IL1RN
|
IL1R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
20959797
17145710
8142597
2876877
24332029
7589429
11641511
9062194
|
LIF
|
LIFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
11306493
19833085
21840487
22595692
24857661
7512720
7521688
|
LIF
|
LIFR
|
â—¼ SHARES_COMPLEX
|
|
|
7.0
|
1.0
|
ACSN
|
11306493
19833085
21840487
22595692
24857661
7512720
7521688
|
LIF
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
971648712707269
14527405
12707269
10811661
16051226
9143707
9716487
|
LIF
|
LIFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
19833085
7521688
23331499
24710148
12601009
11306493
9852103
24857661
7512720
16051226
9143707
9716487
8999038
10428964
21840487
22595692
26192618
8662595
|
IFNG
|
IL18RAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IFNG
|
IL18R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
31.0
|
1.0
|
ACSN
|
10485906
11489965
11579131
11777960
11870632
11964313
12413632
12818165
14607900
15634932
15778339
15811952
15814715
16286920
16424049
16713974
17016554
17559085
1825141
18272812
19833085
20038811
20819927
21149606
21411734
24658051
26755705
2965306
6425450
9834059
9864217
|
IL4
|
IFNG
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
TGFBR1
|
CCL5
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
44.0
|
1.0
|
ACSN
|
11279127
11792802
12809600
14557817
15003992
15099563
15265520
15653932
16127449
16424049
16474430
16572188
17070508
17404308
17768418
17934056
17979848
18423981
18490733
19038247
19109155
19732719
19747910
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
22703233
22874531
23034983
23784029
24132110
24336330
26201938
26966341
2871107
7594497
8515656
|
CCL5
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CCL5
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10734056
7622448
8642344
22633458
10733106
10699158
9289016
|
CCL5
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
42.0
|
1.0
|
Omnipath
|
10734056
7622448
14637022
22633458
9115216
9624164
10699158
11116158
12270118
7545673
9289016
9336350
10910894
8530354
|
CCL5
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
16298345
10488147
28381538
10699158
22633458
9289016
12213786
8663314
11449371
10318947
12964882
25923671
9207005
23480650
11116158
10477718
14637022
9334377
9790730
|
CCL26
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
10699158
16339911
22633458
|
CCL26
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22633458
15039444
|
CCL26
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
29637711
15039444
|
CCL26
|
CX3CR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22633458
20974991
29637711
|
TGFB1
|
TGFBR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ SHARES_COMPLEX
|
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
75.0
|
1.0
|
ACSN
|
10678166
11013220
11133108
11274345
11278410
11279127
11792802
12154066
12717440
12724770
12738796
12767520
12809600
14557817
15003992
15099563
15265520
15282297
15548370
15653932
15761148
15761153
16127449
16200688
16424049
16474430
16572188
17070508
17404308
17673906
17768418
17934056
17979848
18423981
18490733
18758450
18855897
18922473
19010789
19038247
19050695
19109155
19732719
19747910
19920116
20060931
20519943
20538542
20616810
20644162
21041659
21098712
21278795
21372296
21614932
21900405
22315516
22703233
22710166
22874531
22943793
22949611
23034983
23070005
23784029
24132110
24336330
24403530
26201938
26966341
2871107
7594497
8515656
9311995
9865696
|
TGFB1
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
22326956
10187774
7852346
22703233
12809600
7706250
11323414
8047140
8235612
26194464
|
TGFB1
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12867422
25241761
16189514
2119582
|
TGFB2
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22326956
10187774
7608141
11157750
12809600
11157754
|
GDF9
|
TGFBR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
14684852
14514671
27252362
|
TGFBR1
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
14580334
18333754
|
FASLG
|
FAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22075988
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FASLG
|
FAS
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
11003656
11274345
1134007
11583996
12215447
12702723
12724420
14744430
15592525
15760909
16406523
16498403
16940415
17462996
18545270
18641653
19392652
19427028
19498109
19524512
19524513
19597341
19632174
19838173
20452955
20531300
21133840
21232017
22075988
22421439
22427918
23010170
23069999
23073834
23377657
23850759
24366341
24378531
26024392
26587781
26653790
26853145
26900751
26972597
27558815
27984721
28498367
28574505
28645028
9184224
9217161
9488730
9759866
|
FASLG
|
FAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
17145710
8521815
9126929
1375228
1713127
14965271
21803845
9039262
11239407
25241761
9228058
15659383
12753742
7505205
12887920
15725726
|
NGF
|
NGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
10764727
11546791
11756498
12376548
12387875
14673001
15099563
15548667
15721744
16252010
16630834
17488777
17764704
22465479
23314527
25071162
9841888
|
NGF
|
NGFR
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
10764727
11546791
11756498
12376548
12387875
14673001
15099563
15548667
15721744
16252010
16630834
17488777
17764704
22465479
23314527
25071162
9841888
|
NGF
|
NGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10764727
11729324
16893414
2172988
1372492
24224055
14985763
22227462
11114882
15258592
14699954
3037029
1714587
9775403
|
IL2RG
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL13
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL4
|
IL4R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL13
|
IL4R
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL2RG
|
IL4R
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4
|
IL4R
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21115385
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
CSF2
|
IL4R
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10426994
11015446
11280761
11460167
11777960
11907067
12193690
12907458
14660645
15536084
16713974
17301840
18264787
20805416
21133840
21232017
21765015
22869907
24030977
24699077
24958845
|
IL4R
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4R
|
INHBA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL4R
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL13
|
IL4R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12704343
19880493
18243101
8910586
1270434311709750
8920992
7721786
11709756
|
IL4
|
IL4R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
11786020
17145710
18852293
23597562
23331499
12704343
8639787
2307934
7918378
21889455
10219247
17312100
8266078
11815609
10850446
18243101
2278997
791837811786020
9874253
7721786
|
IL4R
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17145710
11815609
12704343
23331499
18243101
8266076
8266078
7918378
|
IL2
|
IL2RG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RG
|
IL9R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
25297818
15143194
1376929
7718508
21439476
|
IL2RG
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RG
|
IL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RG
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
12811837
14607946
15289500
15563472
16212621
16799562
16815076
17371980
17398124
17459805
1825141
18758473
19528259
19833085
19913445
20007590
20856220
21307131
21840487
22224781
23124025
23650441
24829413
25582338
26755705
2965306
6164929
7512720
7521688
7523571
8683106
9625766
|
IL2RG
|
IL15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RG
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2
|
IL2RG
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RG
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RG
|
IL4
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10358772
10485906
10856136
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RG
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RG
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
12811837
14607946
15289500
15563472
16212621
16799562
16815076
17371980
17398124
17459805
1825141
18758473
19528259
19833085
19913445
20007590
20856220
21307131
21840487
22224781
23124025
23650441
24829413
25582338
26755705
2965306
6164929
7512720
7521688
7523571
8683106
9625766
|
IL2RG
|
IL15
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RG
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RG
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RG
|
INHBA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL2RB
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
8568232
15265897
7514277
10903799
11886175
8026467
15933202
7681595
15178252
1545122
8260650
16189514
11851401
8006584
|
IL2
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
15265897
16477002
10807786
19528259
19833085
7521688
17371980
8049354
15563472
18758473
10662798
15289500
23331499
26755705
8683106
23180781
12095053
11418623
6164929
9625766
24829413
1825141
8006584
16799562
7829965
8568232
10820393
7512720
23650441
20856220
7681595
10849428
22224781
1631559
16212621
21840487
26192618
2965306
8260650
23124025
|
IL4
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
18243101
79183788266078
11418623
8266078
7918378
|
IL15
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8568232
9371812
15265897
1526589
10903799
8026467
19710453
11418623
16189514
8178155
78568232
|
IL2RA
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15933202
15265897
8568232
8260650
|
IL7
|
IL2RG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17145710
9371812
11858939
7522165
11418623
8266077
20089933
8128231
9010926
|
IL2RG
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
8568232
15265897
7514277
10903799
11886175
8026467
15933202
7681595
15178252
1545122
8260650
16189514
11851401
8006584
|
CSF2
|
CSF2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2RB
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2
|
CSF2RB
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2RB
|
IL3
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
CSF2RB
|
IL3RA
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL3
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11700046
8649415
18692472
9278420
7957082
|
CSF2
|
CSF2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
1702217
2645577
18692472
8278375
2828352
7957082
|
IL2
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL15
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RB
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RB
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL15
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2RB
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2RB
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL2
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
8568232
3095922
15265897
16477002
11035066
3098894
15933202
1940342
15178252
8260650
3116143
22446627
8006584
8049354
|
IL15
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
23104097
9176231
15265897
10903799
8026467
25416956
19710453
16189514
8178155
|
IL2RB
|
IL2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8568232
15265897
11886175
15933202
15178252
1545122
8260650
3116143
8006584
|
IFNAR2
|
IL15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IL15
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IL15
|
IL15RA
|
â—¼ PROTEIN_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10820393
12811837
14607946
16212621
16815076
17398124
17459805
19833085
19913445
20007590
20856220
21307131
21840487
23124025
24829413
25582338
7512720
7521688
7523571
|
IFNAR2
|
IL15
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR2
|
IL15
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IL15
|
IL18R1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL18RAP
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
10426994
10952726
11907067
14607946
15536084
16713974
17398124
17459805
19913445
20007590
21307131
25582338
7523571
|
IL15
|
IL15RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
17709786
17145710
23331499
15265897
7641685
10903799
19710453
8530383
16284400
|
IL2
|
IL12RB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10807786
11280761
11460167
14660645
15289500
15563472
17301840
1825141
18264787
18758473
19528259
21133840
21232017
22224781
23650441
24699077
24958845
26755705
2965306
6164929
9625766
|
IL12A
|
IL12RB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11086056
943050
8943050
|
IL12B
|
IL12RB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11086056
8943050
1108605611940480
11940489
|
IL1B
|
IL12RB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10198225
7528775
9038232
8943050
9454765
7594594
|
IL18
|
IL18RAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IL18R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IL18RAP
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18
|
IL18R1
|
â—¼ SHARES_COMPLEX
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL13
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL4
|
IL18
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL18
|
CCR7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10679398
11592085
14504095
14662834
15099563
15802534
26885855
27048821
27066895
9469432
|
IL18
|
IL18RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9792649
|
IL18
|
IL18R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25261253
9792649
12096920
11046021
9325300
|
IL18RAP
|
IL18R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IL18RAP
|
IL18R1
|
â—¼ PROTEIN_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10679398
11274345
11592085
12620219
12682231
14504095
14660645
14662834
15099563
15802534
16878026
17704786
23681101
23811849
26885855
27048821
27066895
9469432
|
IFNB1
|
IFNAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
15312780
9121453
10395669
9334213
15778442
12842042
17969444
|
IFNAR2
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR2
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
IFNAR2
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR2
|
IFNAR1
|
â—¼ SHARES_COMPLEX
|
|
|
16.0
|
1.0
|
ACSN
|
11207245
11698286
11964292
12811837
14610620
14764699
15864272
17513775
19833085
21115385
21840487
21930765
21930769
7512720
7521688
7543512
|
IFNAR2
|
IL15RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNA5
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10395669
|
IFNA4
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNW1
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11278538
21854986
|
IFNA2
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
10395669
10339405
21854986
18027911
10984492
17001036
11888273
|
IFNA10
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNB1
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
8181059
10395669
7623815
11278538
1127853810395660
|
IFNA13
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
8181059
10395669
11278538
11698684
21856167
|
IFNA16
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA17
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7623815
21856167
|
IFNA21
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA8
|
IFNAR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10395669
8969169
|
IL2
|
IL2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2
|
IL2RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
15289500
15563472
16212621
16799562
17371980
1825141
18758473
19528259
19833085
20856220
21840487
22224781
23124025
23650441
24829413
26755705
2965306
6164929
7512720
7521688
8683106
9625766
|
IL2
|
LTA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
21.0
|
1.0
|
ACSN
|
10807786
11280761
11460167
14660645
15289500
15563472
17301840
1825141
18264787
18758473
19528259
21133840
21232017
22224781
23650441
24699077
24958845
26755705
2965306
6164929
9625766
|
IL2
|
IL2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
6815536
3095922
15265897
12649439
16477002
15933202
1940342
17032757
15178252
8260650
3116143
8894436
1993646
8580082
8960125
|
IL4
|
CSF2RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
IL13
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
INHBA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
31.0
|
1.0
|
ACSN
|
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20856220
21115385
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
7543512
9834059
|
IL4
|
CSF1
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL4
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11160275
11371360
11867689
11870632
12223527
12401408
12496409
12818165
14610620
16243976
16413922
17404308
17485448
18250477
1825141
19833085
20184663
20406969
20510870
20856220
21469115
21840487
23124025
23390297
24030977
24091328
27216177
2965306
7512720
7521688
9834059
|
IL4
|
CSF1R
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
17.0
|
1.0
|
ACSN
|
10485906
10820262
11160275
11371360
11870632
12401408
12433365
12496409
12818165
18250477
1825141
20184663
20856220
21097505
23124025
2965306
9834059
|
IL13
|
IL13RA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
12223527
12401408
14610620
14657224
15099563
18250477
18451175
20184663
21097505
26755705
9535722
|
IL13
|
IL13RA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
12223527
12401408
14610620
14657224
15099563
18250477
18451175
20184663
21097505
26755705
9535722
|
IL13
|
INHBA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL13
|
IL23A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
10485906
11867689
12223527
12401408
14610620
14657224
15099563
16243976
16413922
17404308
17485448
18250477
18451175
19833085
20184663
20406969
20510870
20856220
21097505
21115385
21469115
21840487
23124025
23390297
24030977
24091328
26755705
27216177
7512720
7521688
7543512
9535722
|
IL13
|
IL13RA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
31.0
|
1.0
|
Omnipath
|
18451175
18250477
20184663
27629921
26755705
23331499
12704343
26471366
15099563
23180781
1270434311003390
23972995
12401408
11003391
14985454
26192618
21097505
20223216
14657224
9535722
14610620
12223527
8663118
|
CXCL10
|
CXCR3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
18514095
18922917
22798340
23567181
|
CXCL10
|
CXCR3
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
18514095
18922917
22798340
23567181
|
CXCL10
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
|
CXCL10
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
9660793
12571234
10233762
9625760
15761110
12750173
10699158
9064356
16189514
12884299
|
CSF2
|
CSF2RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2
|
CSF2RA
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11015446
11306493
11777960
11867689
12393492
12811837
14610620
19833085
20406969
20805416
21765015
22323450
22869907
23046136
24030977
24091328
27216177
|
CSF2
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
23331499
16720384
11091218
11468284
7691413
16492764
9187659
|
CSF2
|
CSF2RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
10753826
8910448
11777960
27396825
12393492
19833085
10572088
22323450
23331499
22869907
9211889
24030977
11306493
11867689
9187659
11015446
1702217
2645577
20406969
23046136
20805416
2828352
7957082
18551128
26192618
18692472
21765015
24091328
27216177
2555171
14610620
12811837
|
IL10RB
|
IL26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20462497
16982608
14764663
23704922
7543512
|
IL10RB
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20462497
16982608
14764663
23704922
7543512
|
IL10RB
|
IL10RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
11207245
11875494
12818165
14607900
14610620
15282297
15579430
15833879
16200688
16424049
16713974
17404308
19833085
20184663
21115385
21191065
21220452
21840487
26755705
7512720
7521688
7543512
9834059
|
IL10RB
|
IL10RA
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
10433356
10542212
10623821
11207245
11875494
12818165
14607900
14610620
15282297
15579430
15833879
16200688
16424049
16713974
17404308
19833085
20184663
21115385
21191065
21220452
21840487
26755705
7512720
7521688
7543512
9834059
|
IL22
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
17208301
23331499
10875937
15120653
18509351
12513909
29608910
|
IFNL2
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IFNL1
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IL26
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17208301
23331499
14764663
23106140
|
IFNL3
|
IL10RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IL6R
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11238858
8706672
23331499
3136546
14656210
9694899
15895091
23663276
7744875
2788034
|
CSF1
|
CSF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
4.0
|
1.0
|
ACSN
|
10705574
11306493
20644254
24669294
|
CSF1
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7883784
8355686
1702217
22483114
22902366
2408759
26235028
22153499
24890514
26095744
|
IL3
|
IL3RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL3
|
IL3RA
|
â—¼ SHARES_COMPLEX
|
|
|
13.0
|
1.0
|
ACSN
|
11698286
12393492
15034038
15549123
15573129
17200410
18633355
22323450
23026134
23046136
23125331
23762788
24778133
|
IL3
|
CD40
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
15034038
15549123
17200410
23026134
23125331
23762788
24778133
|
IL3
|
IL3RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
23331499
11700046
8649415
9278420
7957082
1465408
|
IL1B
|
IL1RAP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9820540
7775431
20802483
|
TNFRSF10A
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9430228
9430227
|
TNFRSF10B
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9430228
9430227
|
CD40
|
CD70
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
16.0
|
1.0
|
ACSN
|
11207245
11581322
11698286
11964292
14764699
15034038
15197224
17200410
17317815
17371980
17513775
23002440
23125331
7523569
8760829
9359474
|
CD70
|
CD27
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
8120384
21917027
26697006
7479974
9862673
8580829
12324477
8186199
9767422
15723067
|
IL16
|
CD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10438516
1851800
7910967
16189514
7615501
|
CD4
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
10816381
29637711
|
IL1B
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
8332913
7878046
1833184
20802483
|
LIFR
|
CLCF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
8390097
9238703
16051226
11943154
|
CTF1
|
LIFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
9030543
11834704
|
CLCF1
|
LIFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10966616
|
OSM
|
LIFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
1536831
16051226
10854424
8999038
1542794
|
LIFR
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
21071413
24710148
12047380
9716487
8999038
16254248
|
OSM
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
16051226
10854424
9143707
8999038
|
OSM
|
OSMR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16286453
23331499
10997905
10854424
8999038
|
IL22
|
IL10RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10875937
|
CSF3
|
CSF3R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
10537111
10364174
15676205
16492764
|
IFNB1
|
IFNAR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15312780
8943354
18508557
15449939
17969444
16171819
|
IFNAR1
|
IL15RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15RA
|
â—¼ SHARES_COMPLEX
|
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNAR1
|
IL15RA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
30.0
|
1.0
|
ACSN
|
10820393
11207245
11698286
11964292
12811837
14607946
14610620
14764699
15864272
16212621
16815076
17398124
17459805
17513775
19833085
19913445
20007590
20856220
21115385
21307131
21840487
21930765
21930769
23124025
24829413
25582338
7512720
7521688
7523571
7543512
|
IFNA13
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
7932753
23331499
8181059
11698684
21856167
|
IFNB1
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
8181059
1834641
10049744
7592797
7623815
11278538
18988627
29311663
112785381834641
|
IFNA4
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA10
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA16
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA2
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7592797
9334213
1834641
|
IFNA17
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7623815
21856167
|
IFNA21
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IFNA8
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7592797
21856167
|
IFNW1
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1834641
11278538
|
IFNA5
|
IFNAR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21856167
|
IL26
|
IL20RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20462497
16982608
14764663
23704922
7543512
|
IL24
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17208301
23331499
1297448111706020
12974481
11706020
|
IL20
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
12351624
11163236
22802649
14580208
|
IL26
|
IL20RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17208301
23331499
14764663
15178681
23106140
|
IL20
|
IL20RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
12351624
11163236
22802649
22232181
14580208
|
IL20
|
IL22RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
11163236
|
GDF2
|
ACVRL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17068149
25237187
|
CCL13
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10477718
9790730
|
CCL3L1
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
11170631
10364178
10477718
16298345
11734558
11449371
11700073
9790730
22633458
12964882
|
CCL14
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16298345
20483925
22633458
11085751
12964882
|
CCL11
|
CCR5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
10477718
9468473
10699158
9790730
11264152
22633458
12964882
|
TNFRSF10A
|
TNFRSF10B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9430228
16319225
|
IL7
|
IL7R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17145710
23331499
8409434
11858939
7522165
2317865
19141282
10390077
8204885
8266077
20089933
8128231
1558969
|
IL7R
|
CRLF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11418668
23331499
10881176
10974032
|
IL34
|
CSF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
18467591
22483114
30205037
22729249
23478061
29796177
31616414
24890514
26095744
|
PRL
|
PRLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
10585417
23048206
2558309
23192981
22325776
23331499
15082796
18988627
9626554
7984244
18253483
10966654
21889455
18467331
11356126
20053995
16546209
29145629
9175708
24243840
|
INHBB
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11266516
|
AMH
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
14656470
|
BMPR2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
7791754
7890683
|
INHBA
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16189514
11266516
|
BMP6
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12297674
|
GDF2
|
ACVR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
27252362
19996292
|
BMP4
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7811286
8702914
11282024
8006002
|
GDF5
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
8702914
15890363
9525338
11282024
16127465
15569154
19229295
|
BMPR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
18756288
10712517
7791754
|
AMHR2
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16446785
14746809
11420127
|
BMP6
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
11401330
10504300
|
GDF9
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
BMP15
|
BMPR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15621726
12044914
12419820
1204491412419820
|
INHBA
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
INHBB
|
ACVR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
ACVR2A
|
GDF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
GDF9
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12135884
|
GDF2
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22622516
19996292
|
GDF5
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
8702914
|
NODAL
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11952836
|
INHBA
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11266516
10746731
1646080
11266510
24018044
9605406
12466190
|
GDF7
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
INHA
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12493742
|
INHBC
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12651901
22710174
|
BMP6
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10504300
|
INHBB
|
ACVR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11266516
1246619011266510
12466190
|
BMP4
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
8702914
23331499
21071413
16446785
12045205
8006002
7673243
7644468
|
BMP4
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
8702914
26330344
20860622
21054789
11241215
8006002
16189514
7644468
|
GDF1
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
INHBA
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
INHBB
|
ACVR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
GDF5
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
8702914
16446785
|
INHBC
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12651901
22710174
|
INHBB
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9202237
|
GDF2
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15851468
27252362
26047946
|
GDF11
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12414726
23331499
1241472616845370
16845371
16446785
|
MSTN
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23829672
11459935
|
INHBA
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
8622651
16446785
9202237
|
BMP6
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
10504300
|
NODAL
|
ACVR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
16446785
11952836
|
ACVR2B
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
23180781
8622651
16446785
12364468
18988627
|
LTA
|
TNFRSF14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
9462508
9153189
11164894
16189514
7995952
|
GDF9
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12135884
10712517
|
BMP5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11580864
16189514
|
BMPR2
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18756288
7791754
10712517
|
BMP6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
11401330
12297674
10504300
|
GDF6
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
9525338
160490149525338
16049014
|
GDF7
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF5
|
BMPR1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
21543859
9525338
11282024
16127465
19229295
|
GDF11
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12414726
|
CTF1
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
9030543
11834704
|
OSMR
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10692570
23331499
21071413
10854424
18988627
8999038
9188471
|
CLCF1
|
IL6ST
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10966616
9143707
|
GDF5
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8702914
23331499
9525338
23180781
18342887
16446785
19229295
87029149525338
|
IFNL2
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IFNL1
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IFNL3
|
IFNLR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17208301
23331499
12469119
12974481
|
IL17A
|
IL17RC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16397230
16785495
8777726
11574464
|
IL17A
|
IL17RC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
17911633
19838198
18684971
|
IL17A
|
IL17RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11058597
17911633
93675399367539
19838198
18684971
9367539
|
LTA
|
LTBR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
7995952
8171323
|
IL33
|
IL1RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
29247993
17145710
29763370
23980170
19559631
19836339
18450470
19996325
16286016
19439663
20926795
|
CCL11
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
9660793
96607939660793
22633458
|
CCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
62.0
|
1.0
|
Omnipath
|
10488147
10699158
22633458
12218106
23597562
25450766
12149192
16102831
8642344
9169459
9005985
16339911
8676064
9276730
9207005
24702154
9712872
10733106
10706854
12761559
8609214
10854442
|
EDA
|
EDA2R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11039935
10484778
12270937
12084975
|
LTB
|
LTBR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8171323
7916655
7995952
12387745
|
GH2
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
2387255
1955498
|
GH1
|
GHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
2825030
8943276
17500058
1549776
9353194
26713839
1935820
31279174
9030599
23331499
7862673
7691587
19927328
10551877
21889455
9571026
3349036
2387255
31100495
29145629
24280222
24243840
|
EDA
|
EDAR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
11039935
18304980
10484778
11309369
11035039
12084975
|
EPO
|
EPOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17145710
8662939
9442088
15358619
9030560
9974393
9774108
18586265
23331499
2163696
10318834
21889455
17327410
16982323
29997244
9808045
|
IL1RN
|
IL1R2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
20959797
24332029
1834644
7878046
1833184
|
IL12A
|
IL12B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
10779781
10899108
8943050
7527811
|
IL12B
|
IL23R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12023369
17587057
|
IL23A
|
IL23R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
1202336912023360
12023369
|
IL22
|
IL22RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
12941475
10875937
29608910
15120653
5898511035029
20462497
18675809
12513909
18599299
11035029
|
IL17RC
|
IL17RA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16397230
16785495
8777726
11574464
|
IL24
|
IL20RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
11706020
|
GH1
|
PRLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
29145629
23331499
24243840
20053995
9556914
27003442
23192981
15082796
7984244
31100495
16546209
|
LEP
|
LEPR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9463481
22405007
12226096
23331499
9207021
9218470
8608603
9786864
|
CCL15
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL23
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9886417
9558365
12381680
10699158
10660125
22633458
|
CCL3L1
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
11170631
11449371
12381680
9115216
9624164
7545673
10202040
10660125
22633458
8530354
|
CCL14
|
CCR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9687537
9548457
15905581
12381680
20483925
9346309
9405404
24218476
22633458
11085751
|
CCL28
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
22633458
12964882
|
CXCL11
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
11110785
22633458
15178708
|
CCL3L1
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11449371
7594543
22633458
|
CCL15
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10699158
9346309
|
CCL13
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9276730
10733106
9005985
10699158
16339911
22633458
12149192
|
CCL14
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9548457
9346309
11085751
|
CCL24
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
16102831
10488147
15207250
22633458
10733106
10699158
16339911
12218106
|
CCL18
|
CCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
10640766
29637711
23999500
24218476
22633458
23951310
|
IL31
|
OSMR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16286453
23331499
15184896
|
BMP15
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15621726
23331499
12419820
16446785
|
GDF2
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
28646109
15851468
|
BMP6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
21071413
16446785
11401330
10504300
|
GDF7
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16049014
|
GDF6
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
9525338
16446785
18988627
160490149525338
16049014
|
GDF9
|
BMPR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
1213588412135880
12135884
|
CCL20
|
CCR6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
10498628
9223454
10488147
9169459
9294137
10699158
12081481
24218476
22633458
12964882
|
CCL20
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9660793
|
INHBA
|
ACVR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
INHBA
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
81675688397373
8167568
8397373
16189514
9605406
7890768
|
INHBB
|
ACVR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11117535
8196624
15123686
8622651
9032295
|
INHBB
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
11266516
15196700
12032389
|
INHBB
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15196700
|
CCL13
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9660793
|
CXCL13
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11554781
16189514
22633458
|
CXCL11
|
CXCR3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
15273303
9625760
15761110
12750173
10699158
16189514
11259614
12884299
|
AMH
|
AMHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
8889695
23331499
8119126
16446785
18988627
79972308889695
7997230
|
CCL27
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
10781587
11821900
12718728
10725697
22633458
|
CCL28
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10975800
10781587
22633458
|
CXCL13
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
CCL25
|
CCR10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10706668
|
GDF1
|
ACVR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
NODAL
|
ACVR1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19874624
11952836
|
IL27
|
IL27RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23331499
14764690
12121660
18988627
17318299
|
EBI3
|
IL27RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12121660
|
THPO
|
MPL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
23331499
8521814
11784712
9766811
7543416
9252374
10495959
|
IL17B
|
IL17RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
10749887
24011563
11058597
1074988710749880
|
IL25
|
IL17RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
24011563
11058597
19838198
1105859711058590
|
CCL17
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12832759
10699158
9521068
10910894
|
GDF1
|
ACVR1C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
ACVR1C
|
NODAL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
15485907
21229555
21356369
15150278
15531507
|
NODAL
|
ACVR1C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12606401
15531507
|
IL24
|
IL22RA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17208301
23331499
12974481
|
CCL1
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
35.0
|
1.0
|
Omnipath
|
12967681
16221874
9207005
12645948
9211859
11470772
10699158
11154210
9469461
10419462
10910894
|
IL31
|
IL31RA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
15184896
15194700
|
CCL25
|
CCR9
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
10498628
10699158
11159507
22633458
10229797
|
CCL18
|
CCR8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24218476
23999500
|