ESR1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16144913
|
ESR1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16144913
|
ESR2
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9841885
|
RARA
|
ESR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9841885
|
TIF1B
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
20858735
17056014
32807901
20864041
|
TRI33
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20603019
34079125
|
ANDR
|
CBX5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33640491
34585037
|
CBX5
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10562550
21531907
|
PPARG
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
32929351
|
ESR1
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
ESR1
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
CDC16
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CNKR1
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NTAQ1
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN785
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN331
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RFPLB
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
ZN133
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
Z324B
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN764
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZIM2
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN254
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN264
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN550
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN483
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN695
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
Z324B
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN331
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZIM2
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN254
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN764
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN264
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN785
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZN695
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
ZIM2
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
Z324B
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CBX5
|
ZN764
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
20562864
|
CDC16
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
31753913
23160376
|
NADC
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
TIF1B
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21531907
28068325
33961781
29955894
|
NADC
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NTAQ1
|
TRI33
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
31753913
|
CBX3
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
34079125
10562550
16713569
21531907
|
PPARG
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11500849
35140242
11877444
30595551
|
ESR1
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9717844
23403292
9121466
|
ESR2
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21182203
21951318
|
CBX3
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
30804502
27248496
24981860
21888893
14578449
|
TIF1A
|
ESR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
11500849
29509190
21182203
10598587
|
ESR1
|
RARA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9717844
25303530
25604459
|
TIF1A
|
P53
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24820418
22389628
19556538
|
P53
|
GCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11080152
16189514
11562347
16713569
|
THA
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9115274
31753913
|
TIF1A
|
GCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31182584
9115274
|
CBX3
|
CBX5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
ESR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MCR
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10935545
11518808
9115274
|
MCR
|
GCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11154266
16131566
|
P53
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16713569
26556313
10766163
17545634
21761334
|
TIF1A
|
ANDR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19909775
16713569
9115274
33640491
34585037
|
TIF1A
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21531907
31753913
21164480
|
TIF1A
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29021135
34079125
32677374
29129908
21164480
|
TIF1B
|
GCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9742105
22863883
|
CBX5
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17314413
11336697
16713569
20850016
27705803
20231385
33961781
21888893
24981860
15306854
34079125
20562864
19498464
|
CBX3
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10562550
10330177
11336697
20850016
32068487
29955894
27705803
33961781
21888893
20936779
20675861
34079125
|
CBX5
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18404153
11336697
30804502
33961781
21888893
24981860
30021884
15306854
|
PPARG
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22363753
16189514
12763030
10944516
31547433
30404011
20211142
35140242
25609649
17312272
23703729
7838715
19047629
12966085
22205725
14587029
10882139
30595551
30699358
9065481
21833030
9568716
34081964
21478865
9121466
23275339
17579352
19147680
26260846
16713569
12591919
10854698
30651555
32929351
23711995
11877444
15888456
18217139
19043829
17980149
|
ESR2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29509190
12630920
17991765
21182203
19022902
10706629
19746436
9473491
|
RXRA
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
ESR1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
TIF1A
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12684500
30479348
29955894
34518220
21531907
|
TRI33
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24820418
12096914
30479348
26496610
31753913
21531907
24981860
|
RARA
|
TIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
12503607
8598193
16713569
9115274
|
TIF1A
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
11851396
8598193
9632676
9115274
|
RXRA
|
RARA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5212283
10698945
|
H31
|
CBX3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24576085
16415788
34133717
26527279
24981860
20011120
15136563
33097091
|
CBX5
|
H31
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
16415788
26157143
16687578
26527279
33961781
24981860
19783980
34079125
20011120
16622419
25281560
19498464
|
TIF1A
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9115274
9259327
10598587
23403292
21182203
9632676
8598193
9774463
21164480
|
THA
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
16189514
1331778
19422879
11117530
1314167
15604093
|
CBX5
|
TIF1B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
31427381
12154074
19498464
10330177
32068487
23645696
12411497
21888893
22496453
10562550
22205726
10938122
15882967
11336697
27705803
33961781
24981860
24018422
20562864
|
RARA
|
RXRA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
9415406
25241761
21988832
16540467
15604093
1310351
10698945
14521715
12052862
9582446
19345331
31700049
7760852
15528208
21478865
9121466
10882070
16769902
15171703
22539306
25303530
7705655
16713569
1314167
16224062
|
PPARG
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
RARA
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
H31
|
H4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
8598932
25416956
30804502
23319141
27248496
16622419
19498464
20080577
14578449
29568061
21724829
19410544
26527279
18571423
25533843
19766566
22828868
14718166
20739937
33961781
20498094
34079125
|
RXRA
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
12763030
25609649
20211142
11877444
16504037
17579352
16713569
9065481
22205725
23331499
22363753
10854698
19147680
19043829
12591919
9568716
10882139
10935544
17980149
26260846
21478865
14587029
23711995
9121466
18217139
31547433
7838715
19047629
23275339
21833030
12966085
17312272
11237216
15888456
|
ESR2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
14754635
24284820
15207704
18784357
11566442
12630920
22820289
19001520
18511514
14676837
19207817
22622808
21763263
18339713
15087130
|
ESR1
|
RARA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
8300756
8912864
8732679
11038749
15831516
15870697
10076999
9626663
18414489
|
ESR1
|
ESR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12630920
9473491
19746436
21182203
10706629
10022879
|
ESR1
|
RARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
17641689
15831516
9717844
9841885
|
RARA
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
50.0
|
1.0
|
Omnipath
|
15528208
19345331
16713569
16769902
21988832
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