Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RRAS RALGDS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7809086
H3-4 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 RAPGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 RAPGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
CTNNB1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21772333 19213727
FBXW11 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22017875 21900206
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
NEDD4L RAPGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8289927 21765395
YWHAZ RAPGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
UBC YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAZ KIF5B â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
KIF5A KIF5B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
UBC XIAP â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
PHB2 XIAP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
YWHAZ YAP1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5217040 15161933
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BTRC UBC â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
BTRC YAP1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CTNNB1 FBXW11 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
YAP1 BTRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
RRAS2 RALGDS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 11788587
RALGDS RRAS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 11788587
YAP1 YWHAZ â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HRAS RALGDS â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
CTNNB1 RAPGEF2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
NEDD4 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NEDD4L UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BTRC YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20048001 23431053 24976009 21900206
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
FBXW11 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23331499 9784611 22682247 10074433
HRAS RALGDS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 17145710 11786539 20936779 10922060 25241761 24441586 11313862 7972015 9150145 15031288 9154803 8550624 9038168 10783161 7809086 10545207
KRAS PRKCQ â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 23943869 26590425 9436858 11585916 29311131 20802526 25713064 16483930 24033119 27697864
KRAS RALGDS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10783161 7809086 21988832
PRKCQ RAPGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18796635 22888329
RAP1A RALGDS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8636102 10922060 10022812 23236378 10085114 7809086 11786539
RAP2A RALGDS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10085114 11786539
RAPGEF2 RAP1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10608883 10934204 10608844