Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RRAS FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN RRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17474147
FARP2 SEMA3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16286926 10679438
PAK2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
PAK3 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PAK1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7215301 19264842
PAK3 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
RAC1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK3 RAC1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PAK2 PAK3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
FYN GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
NRP1 GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
GSK3B CDK5R1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
GSK3B SEMA3A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
GSK3B CDK5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
GSK3B PLXNA4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
CDK5 SEMA3A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12372285 17607942 14685275
SEMA3A CDK5R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12372285 17607942 14685275
SEMA3A NRP1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 25335892
PAK2 RAC1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CDK5R1 CDK5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 23543736
CDK5 CDK5R1 â—¼   PHOSPHORYLATION ✅ - 0.94 0.94 Signor 18326489
PAK1 PAK2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23455922 32707033 31980649
NRP1 SEMA3A â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
RAC1 PAK3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11478794 11862216 25301945
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
CDK5 CDK5R1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
CDK5 CDK5R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11583627 23602568 15689152 11389014 17036052 25076872 21220307 15890360 16189514 23979715 26186194 17591690 17762160 14521924 20133653 22654103 28637746 12223541 23543736 18326489 28077789 17121855
CDK5 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20058876 17114649 12176333 12950086 19298660 19664994 12176334 15542607 19413330 23537649 19036346 19664995 21825040 11604394
SEMA3B NRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25335892 10196546 16189514 10196540
SEMA3A NRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9331348 25335892 10196546 10520994 10498602 29067024 15721238 15121181
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
RAC1 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 8107774 10023776 8805275 9744077 23331499 8910277 22705156 20936779 9535855 19264842 19628037 11728826 20696164 16212495 12480336 11152757 9823899
RAC1 PAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9744077 10023776 8805275 16212495 12480336 11152757 25301945 11728826 11478794 8910277
SEMA3A PLXNA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25335892 15814794 15721238