Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2V1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1551980 11057907
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
IRAK4 PELI1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0900774106 19264966
IRAK1 PELI1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0900774106 19264966
PELI1 TRAF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12804775 16951688 29720226 12496252
PELI1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MAP3K7 RIPK2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RIPK2 TRAF6 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 9642260 18329614 21097508
IRAK1 MAP3K7 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
IRAK4 TRAF6 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23381138 16189514 11960013
IRAK4 IRAK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20485341 21903422
IRAK2 IRAK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12138165 21903422 10383454
PELI3 M3K7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12874243 15917247 18326498
IRAK2 TRAF6 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
TRAF6 UBE2V1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PELI3 TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18326498 25027698 12874243 15917247 23042151
IRAK2 TRAF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33799071 21988832 9374458 33961781 26250868 10383454 17878161 21903422
PELI2 IRAK4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12860405 17675297
IRAK1 IRAK4 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
M3K7 TRAF6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31127032 22924441 28024152 10921914 27249171 19232515 10882101 16543409 19675569 24434549 10094049 33768585 18758450 19521662 11259596 22851693 19843958 12496252 11518704 14633987 12242293 21822258 19112497 27501752 19820695 16517750 22643835 26038599 31885808 25963657 12609980 31404116
TRAF6 UBE2N â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18710948 17327397 15147900 17709375 21113135 27791197 19810754 24610907 29950522 27695001 27918549 31074699 34490261 18617513 30979779 25548215 11057907 19465916 29537486 31638574 15327770 19549727 31578830 27173435 28244869 29432170 23885119
UBE2N MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17965022 17079228 10702308
IRAK2 MAP3K7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15327770 19675569 10882101
PELI1 IRAK4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 17675297 12496252 19264966 21204785 16951688 17997719
IRAK4 IRAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 12860405 19166926 18221795 12538665 17785851 11960013 16024789 16951688 17276401 21903422
PELI3 IRAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16884718 17675297 18326498 25027698 12874243 15917247 19081057
PELI1 IRAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16884718 26082489 17675297 12496252 19264966 21204785 15917247 16951688 17997719 19081057
IRAK4 PELI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
IRAK1 PELI3 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
IRAK1 PELI2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
TRAF6 IRAK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18347055
TRAF6 MAP3K7 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18758450
IRAK1 PELI1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
IRAK2 IRAK4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
IRAK1 TRAF6 â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
TRAF6 IRAK1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22033459 24735611 11397809 19716405 17197697 30872404 8837778 10346818 17785851 11960013 18234474 16951688 16024789 11287640 12034707 21220427 23381138 19166926 24434549 28882891 18056395 11259596 23244239 12496252 22447928 20043910 12566447 11518704 12242293 10920205 10383454 18347055 9374458 31921110 14625308
PELI2 IRAK1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16884718 12370331 17675297 12860405 25027698 15917247 19081057
TRAF6 UBE2N â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAP3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TRAF6 IRAK1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 MAP3K14 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
UBE2N TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 18710948 1551980 17327397 11057907 15147900 18981220 21113135 17709375 31074699 19549727 18617513 24610907 27791197 29432170 19465916 23885119 15327770 27173435 21872579 25548215
IRAK4 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12496252 16189514 11960013
IRAK1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 10346818 17145710 17785851 16024789 14625308 11259596 10383454 18234474 9374458 11287640 23244239 21220427 11518704 19166926 16951367 15894263 10747026 35926385 18056395 12566447 12496252 22447928 12242293 8837778 10920205 11960013 19716405 24735611 20043910 24434549 17785432 11397809 18347055 22033459 12140561 23381138 17197697
IRAK2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 21988832 10383454 21903422 9374458 12659850 17878161 26250868 24973222 33799071
TRAF6 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9275204 11278268 25241761 16286467 10921914 16189514 10075662
TRAF6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 19675569 17947236 19843958 10882101 19521662 11259596 17079228 28024152 31885808 19112497 22924441 10094049 27501752 18922473 11518704 11809792 16517750 19232515 10702308 16410796 14633987 19820695 22851693 10921914 18758450 12496252 12609980 21822258 12242293 25963657 24434549 27249171 22643835 21245467 17965022 26038599
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
PELI3 PELI2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17675297 12496252 12860405 15917247 17997719
PELI1 PELI2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17675297 12496252 12860405 15917247 17997719
IRAK4 PELI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17675297 17145710 12860405
PELI2 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 18326498 12370331 17675297 17997719 12860405 16884718 19081057
IRAK1 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12242293 17197697
RIPK2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18079694 17079228 17947236 10702308 17348859 17965022 15075345
MAP3K7 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 10094049
IRAK4 IRAK1 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IRAK1 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 12738796 14504095 14660645 14662834 15099563 15125833 15802534 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849 26885855 27048821 27066895 9469432
IRAK4 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17145710 17785851 18252867 17276401 16024789 14625308 15084582 21903422 15292196 25452754 19775907 18221795 15905496 19166926 12538665 12860405 14751757 12496252 11960013 24735611 26143580 17337443
IRAK2 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK1 IRAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 10383454 21903422 16024789 12138165 24973222
PELI3 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 18326498 17997719 17675297 12874243 16884718 19081057
IRAK1 PELI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 17997719 17675297 16884718 16951688 19081057 26082489 12496252 19264966
IRAK1 PELI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 18326498 17997719 17675297 12874243 16884718 19081057
PELI3 PELI1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17675297 12496252 12860405 15917247 17997719