Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRIN2A LRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
MAP2K3 MAPK14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
F2R MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
NFATC2 NFATC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19564342 11786533
NFATC1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18962896 21398617
CREB1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
IL10 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12773629
RELA CCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALM2 ITPR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7755592 10456332
SRC ITGB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
ITGB5 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19910644 10592173
CYSLTR2 GNAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ITGB3 ITGAV â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214491 11546839
EPO PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
PLCG1 F2RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRIN2A PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9231720
AVP GNAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9756892 8621513
CHRM3 GNAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
MC5R GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31160049 20371771
ADORA2A GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8995267 6162091
RELA F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11463837 19351910
RELA CRHR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20233629
RELA AGER â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18622638 19616578
SRC F2RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC F2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC AXL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22327215 8381689
SRC ADRB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219452 17170700
SRC F2RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17474147
GULP1 ITGB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12606711 5216162
CREB1 ADRA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10520459
CREB1 ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1356108
CREB1 NPY â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12967770
CREB1 AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15089973 9389510
CREB1 GALR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15934937 11145992
MAPK11 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11532940 11335727
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPB GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15299028 22074460
GAS6 MERTK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19631584 25695599
MAP2K3 MAPK11 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8622669 7535770
GRIN2B CAMK2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8294337 19453375
CAMK2A GRIN2B â—¼   COLOCALIZATION 2.0 0.8 intact 8294337 19453375
GNRH1 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12810529
NR1H2 ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25838426 20951680
NFATC1 F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19460777 19351910
ADRB2 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
HTR4 ADRB2 â—¼   PROXIMITY 2.0 0.8 intact 5217738 15896782
DRD4 ADRA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22723743 1001347
DRD4 ADRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22723743 1001347
DRD4 ADRA1B â—¼   PROXIMITY 2.0 0.8 intact 22723743 1001347
DRD4 ADRB1 â—¼   PROXIMITY 2.0 0.8 intact 22723743 1001347
NPBWR2 NPW â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12719537 7590751
NFATC3 EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20647310 24291639
NMB GRPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1655761 8383682
F2RL2 F2R â—¼   PROXIMITY 2.0 0.8 intact 17376866 0700763104
F2RL1 ADCY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
F2RL1 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CHRM3 BSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
LPAR1 ITPR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CALCRL GNAS â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
GNA13 DRD5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12623966 16189514
NR1H2 ABCA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23931754 25838426 20951680
GNA12 DRD5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12623966 16189514
C1QC C1QB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21054788 16189514 12960167 28325905
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EDN1 EDNRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 10770212 16713569 7509919 23597562
SRC PLCG1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 1689310 7510703 16713569 7682059 8657103 8885868
GCGR GNAS â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
DOCK1 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17474147 12615911
NMBR NMB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10544247 8253343 8392057
PLCG1 GHR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17474147 9632636
NTRK1 PLCG1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
C1QB C1QA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14681455 21054788 12960167
SRC ADRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11013230 17170700
NPY1R NPY â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 12007534 9001438 23597562 7559383
GABRA1 GABRG2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DUSP4 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16849326 16189514 11387337
MAPK14 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11278789 10806218 12917630
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 DUSP5 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 17208316 22569528 20463170
MAP2K3 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8226933
NFATC2 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18962896 21398617 22427656
C1QC C1QA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14681455 21054788 12960167 28325905
GIP GIPR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15655707 17715056 12627975 8795084 7589426
AXL PLCG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 9178760 8026679 1201123
NTRK1 PLCG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25921289 9856458 1715690 8384556 10092678 1400471 10708759
SRC PLCG1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
GNAS ADORA2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 17371980 17909080 18758473
GNAS ADORA2A â—¼   SHARES_COMPLEX 3.0 0.9 ACSN 17371980 17909080 18758473
GNAS ADCY9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
GNAS ADCY7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9228084 21406690 32196115
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
NR3C1 GZMA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17180578
CEBPB CSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10855690
CEBPB AVP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8466483 15123720 11414683
MERTK GAS6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17442946 16737840 17064312
CAMK2A OPRM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10908300
CAMK2A GABBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20643921
NR1H2 NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12470667 11875109 22194611
LPAR1 GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31160049 15856019 20331961
MAPK9 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16648474 10978313 11274345
F2RL2 F2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 873923 8615752 10079109
F2 F2RL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 873923 8615752 10079109
F2RL2 F2 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
F2 F2RL3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 9618465 9087410 1672265
F2R GNA15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 10644723 31160049
GAS6 AXL â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 16362042
C1QB C1QC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ELMO1 DOCK1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 12134158 5215575
CALM2 CAMK2A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MAP2K3 MAPK14 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
ADM CALCRL â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
GIP GIPR â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
F2 F2R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ADCY9 GNAL â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
AXL GAS6 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ADCY9 GNAS â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
DOCK1 ELMO1 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
F2 F2RL2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
F2 F2RL3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CSH1 CSH2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DOCK1 ELMO1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21930703 16495483 15723800 28514442 18768751 15247908 12134158 11595183 20732417 33961781 26186194 26882976 20016009
C1QA C1QC â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
C1QA C1QB â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CAMK2A GRIN2B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SRC LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12789267 11854294 18381291 21650223
DUSP8 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 8910287 10915787 23159405 9922370
MAP2K3 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 12589052 11279118 17081983 20213747 7914033 18767875 17322306 23602568 8622669 18855897 19690332 23904011 9162092 11426938 15592455 18083107 7997261 12384504 15735649 18291705 23331499 17389395 7535770 19534553 7839144 21071413 16083285 21614932 20068231 12738796 16189514 17255949 18669648 16153436 14970210 26186194 16407200 11242034 18691976 18088087 11304531 15972258 10781613 17192257 18586681 10734320 19651622 7592586 16157584 19369195 9582275 15674326 9528766 7693711 9841871 12758252 11309380 7750576 15212693 15659558 11274345 15735648
DUSP2 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 8626452 7535770
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 15649893 16648474 11997522 10747897 18347059 17255949 11274345 12697810
MAPK14 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15187187 18039929 12738796 11274345 12697810
MAPK14 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
MAPK14 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11175347 12356771 15733869 11160957 11532940 7958915 9829964 12235136 16189514 11335727 9687510 8887554 11698596 23532963 8688081 9528766 11018520 11969286 11377386 11909979
MAPK14 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 25847991 12351702 28582465 31974640 20047289 22911818 19841061 12000743 15817653 20660302 17570479 22401993 17440046 17185395 24024586 19812390
MAPK14 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15649893 20516082 16648474 12944472 11997522 10788511 15304486 10747897 17255949 10652349 11274345 12697810
MAPK14 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15649893 20516082 16648474 15121840 12944472 10788511 11030334 10747897 17255949 11274345 12697810
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
DUSP5 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23331499 10224087 12944906 7836374 19741200
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAPK13 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
DUSP4 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 15315965 18988627 7535768
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK3 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15994958 11278789 12917630
MAPK3 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15657420
MAPK3 NFATC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10652349
MAPK3 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12351702 17440046 9199329 20047289
NFATC1 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19915002 18078995 15657420 18299389 16455648 11402342 11030334
MAPK9 NFATC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14517246 15184502 16648474 10978313 17570479 15958558 11274345
MAPK9 NFATC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16648474 10978313 17875713 27893713 11274345
CREB1 IL10 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11579131 15187187 15749884 16007092 16713974 17404308 20547845
RELA IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18760861 9310124 19124729 19122653 18077329 22070873 27324129
CEBPB IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24715531 17525287 12493739 12847250 16413748
CREB1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22140263 26408955 21986577 19564345 12493739 22116830 10540320 18263767 17202341
CCK CCKAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 10368033 9006937 10595537 11300760 10400673 9603948
CALM2 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9952395 8625412 12379661 9728925
CALM2 CAMK2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3006921 17353931 20668654
GIP GIPR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 12627975 26572091 17715056 8795084 15655707 7589426 15655705
ITGAV ITGB5 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGAV ITGB5 â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
ITGB5 DOCK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
GNA15 CYSLTR2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309
ITGAV ITGB3 â—¼   PHYSICAL_INTERACTION 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV ITGB3 â—¼   SHARES_COMPLEX 23.0 1.0 ACSN 10022831 10545505 10837075 11146654 11335727 11532940 11553709 12000961 14697347 15031725 16919435 18353785 19161977 19339212 19449109 22035837 7512751 7529872 7657702 8636223 8755653 9295024 9763615
ITGAV DOCK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10837075 11146654 14697347 15031725 18353785 22035837 22470492 9295024 9763615
PLCG1 SRC â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
PLCG1 SRC â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
SRC PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 8388373 16497976 16126727 16713569 17389395 1689310 20068231 17570479 16153436 16038803 1708307 7682059 7510703 18594017 12601080 8885868 8657103 17016520
AXL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9178760
NTRK1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10708759 23331499 1400471 8552402 9856458 21071413 8384556 10092678 25921289 18988627 1715690
GHR PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17474147 9632636
ADORA2B GNAS â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
ADORA2B GNAS â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 2553705 3127824 9651336 12106601 12860470
ADRB2 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12036966 15782186 23798571 6149763
GNAS ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9228084 9395396 1719547 9268375 21406690
GNAS ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9228084 9748257 9268375 21406690
CREB1 RELA â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
CREB1 RELA â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 11579131 12417340 15079071 15187187 15279786 15337521 15536066 16007092 16713974 17303408 17550372 17565603 17660363 18590585 19171876 19879327 20144767 23430059 7575488 8383323 9743347
RELA EDN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21334436 10969841 18226221
RELA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10833420 20966071 16317091 7536741 16627481 16385502 10946302 19422386 22708120 23042817 19281832 10553096 10329958 11359843 7692229 16249517 10496926 7537851 16453001
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
SRC GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10884433 18184784 11483655 11024032
SRC CDH5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 36.0 1.0 Omnipath 28712573 24525631 26504080 24590762 25675998 25447529 24358106 27381080 20708398 33836597 26905827 24136461 19644057 21123455 24446483 22648953 22897853 24583284 29326721 16909109 33604918 21037229 25924235 28057793 28119542 16027153 26598555 33712448
SRC ITGB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10330414 17473008 8631894 18156175 25694433 18840695 18364349 18398066 10592173 16935858 21956114 17353363 18088087 12359711 15212693 14996908 15695822 15699036 11723131 20702409
SRC BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10085087 16226010
SRC GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10884433 10458595 10195142 23933820 12932824 10846184 29063113 26942227 19834457 33037073 11677266 26441533 20448061
CREB1 GRIN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15774772 16313514 23012887 22364833
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
CAMK2G CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CEBPB ARG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9013624 15922518 19805133 8612622 23913966
CEBPB ADRA1D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16431954 10796884 10051504 10871045 11058951 11481261
CEBPB ADM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12630823 9480831
CAMK2A CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1314426
NR3C1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25202013 9817600 9428795 11279134
GAS6 MERTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 27801848 8939948 9160883
GAS6 AXL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 7867073 23331499 8621659 27801848 8939948 27829217 12218057 7854420 18988627 16362042
CALCB CALCRL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 2177866 8626685 2985435 6609312 14722252
ADM CALCRL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11693189 10347248 9620797
CALCB CALCRL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11693189 8626685 3001670 12196113 12234182 14668209 10347248 9620797
MAP2K3 MAPK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18291705 11704645 23331499 11242034 19369195 21614932 14724572 12738796 11274345 18083107 18855897
MAPK11 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
CAMK2A GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12147342 11306676 19453375 21610080 16120608 8940188 11459059 22427672 16436603
NR1H3 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 12032171 19718435 17587765 15280160 12198243 21219878 11788472 11641412 15292368 16141411 14764426 22305277 23466610 24603323 22429094 15922656 22389325 15171719 21521932 15949682 19342446 22683903 23523156 17526932 18580406 16254209 16901265 18372238 11287605 17887732 20570635 15774904 16099444 10858438 11264984 19787078 17026988 22711909 23686490 16803904 16730733 19201410 17135302 19258656 20419060
F2R GNA13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8290554 20223821 10922491 16189514 22318735 22972936 21331223
NR1H2 ABCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15831500 16141411 15292368 23523156 16644917 20951680 16825483 21507939 19258656
MAP2K3 MAPK13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 11242034 21614932 12738796 11274345 9374491 18083107 9790884 18855897
MAPK9 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12351702 18337589 9482836 9199329
F2 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9058715 10978167 15707890 10644723 14652070 11356985 23450633 18250335 12563219 22972936
F2 F2RL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10978167 1135698510978160 11356985
F2 F2RL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1273221212732210 12732212 22318735
F2 F2RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11356985 12732212 1135698512732210
GH2 GHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2387255 1955498
GNA15 OPRM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9544801 16415903 11786497 10215864
LPAR1 GNA12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22863277 31160049 15856019 20331961
F2R GNA12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8290554 16189514 31160049 22972936
KNG1 BDKRB2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18127230 3366244 8063797 1314587
KNG1 BDKRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9203620 8063797 8302267 28966616
NPW NPBWR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12130646 12401809 12719537
NPW NPBWR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12130646 12401809
EDN1 EDNRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 90829707 6479761 9082970 7509919 16597412 16713569 23597562 15629009 8440682 7647976 10770212
NMB NMBR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 1655761 11313903 25976083 10454496 10544247 8392057 18055507 7838118 15169928 8253343 21729729
NPY NPY1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 7559383 16189514 9549761 23597562 9001438 12007534
EDN3 EDNRA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 1710450 1719979 8440682 2649896
NMB GRPR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 1655761 1720612 10454496 7838118 19463875 21729729
GNA15 CYSLTR1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 10191087 3086311 16754659 1905813 8664309
OXT AVPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 9884074 9322919 12660315 9264324 7774575 9459574
OXT AVPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9884074 9322919 9264324 9459574 16158071
AVP AVPR1B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2991279 4065330 8106369 7929452
AVP AVPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 15084136 10519430 12446593 10780976 9884074 1560825 9322919 11012895 9264324 7774575 11857925 9459574 9864265
AVP AVPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 15084136 10519430 12446593 10780976 9884074 9322919 9264324 9459574 16158071 7929452 9864265
NPY NPY4R â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 1317848 3202875 7592911 7592910 6373251 6589611 10461880
NPY NPY4R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7592911 7493937
DUSP4 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8626452 32296183 25241761
MAPK9 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12917630 15994958 11278789 20068231
MAPK9 NFATC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14517246 16648474 10978313 23047924 9374467 9630228 11274345
KISS1 KISS1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 15665093 11457843 11385580 12944565