Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
PIN1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9499405
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
PIN1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11774038 16713569
NPM1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219698 17318229
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK3 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MYT1 YAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 30312684
MYT1 PLP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8530187 12356912
NPM1 MYT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK3 RPS6KA2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MYT1 PIN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10504341 16713569
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PLK1 PIN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10037602 9499405 16118204 16713569 16189514
AURKA PIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23970419
NEUROG3 GCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21395400 16809427 21983268
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MAPK1 MBP â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
HDAC1 SIN3B â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MAPK1 MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 11258664 17255944 12760422 10371216 12944901 1939237 9792705 16401070 15380617
MAPK3 MBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 10339476 16401070 1939237 1699809
MBP PLP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 2467009 6083474 16713569
AURKA PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 18566290 23618492 27721411 24338364 15713655 28126323 34260926 19364923 33805672 33771996 32284347 27504491 33898950 10980711 26206521 21474997 32060423 27662907 28994651 33963314 18615013 23695676 34197606 18669648 25925375 26114094 19228686 28591578 22281053 18691976 20603326 15611664 27068477 27908669 26919439 26012549 18477460 34140642 25660017 27899378 19369195 21454580 25871386 24349352 12207013 20869364 11854496 20633640 28351953 24667170 25042804
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
MYT1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 61.0 1.0 Omnipath 17145710 19901323 25733813 26658951 25609063 19413330 11202906 17480229 20798132 14972559 19415658 20362450 22621333 22709126 25301733 9552418 24651440 16083285 24143279 20068231 18452278 12912980 25344910 28264028 11730318 18669648 22836368 27669826 18691976 18378775 17718912 23410205 23301080 20068230 10504341 20419782 19651622 9001210 9268380 10209160 24136233 23494566 25435947 20530684 27170181 15837193
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
NPM1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 23602568 8939914 12832467 17906627
PLK1 MYT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28415805 12738781
PLK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19651622 17081983 20068231 27619510 15190079 20352051 19413330
PLK1 PIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27618008 23633483 16118204 9499405 16713569 25070718 25766872 10037602 22926167