Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MECP2 OPTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OPTN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11137014 5213395
OPTN MGARP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MECP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DAPP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
MGARP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TARDBP APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MECP2 MGARP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMN1 MGARP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP PSEN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
A2M MGARP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP TRIM54 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
MGARP TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MGARP GDAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SP1 MECP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15109260 20385708
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
TRAK2 TRAK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 12435728 33961781 26186194
HTT OPTN â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
MECP2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21655924 23242655 15870696
SMN1 A2M â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TRAK2 RHOT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16630562 19103291 30111583
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
SP1 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8921911 18586551 18608091 21056687 24946209 11724400 9867871