Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NOTCH1 DLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 20351093 22363487
NOTCH1 DLL1 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 20351093 22363487
NOTCH1 LFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15207708 22298955
MESP2 ITF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MESP2 HTF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MESP2 TFE2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
HTF4 TFE2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12566462 9050988 21828274 1446075
ITF2 HTF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 25609649
ITF2 TFE2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 20211142
MESP2 NOTCH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17306789 12900443 15902259
TBX6 MESP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18849530 20346937 16505380
DLL1 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17537801 11006133 9819428 21685328 1006133 16140393 98194281 22353464
LFNG NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10935626 16713569 12486116
NOTCH1 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11604490 16713569 18988627
NOTCH1 LFNG â—¼   GLYCOSYLATION ✅ 5.0 1.0 Reactome 10734111 16385447 9187150 10935637 9207795
TBX6 DLL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12620991 15986483 15545628 17584735