Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 EEF1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15501971 12857899
TRIM31 MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MIEF1 MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
UQCRB MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SH3GLB2 MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAGEA1 SH3GLB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
UQCRB MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MIEF1 MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TRIM31 MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SH3GLB2 MAGEA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAGEA1 SH3GLB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
MDM4 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 19521340 7290688
TP53 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7711923 20206173
SNW1 RBM22 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34133714
NOTCH1 SNW1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CBX4 PCGF6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 33961781 27705803
PCGF6 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22325352 27705803
MAGEA1 S100A9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MAGEA1 S100A9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PIAS1 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NOTCH1 FBXW7 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 23022380
EID3 NSMCE2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L MIEF1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 EEF1A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23799104 9269753 18431400
TP53 FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23518350 19366810 12824889
TP53 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31346036 12824889
NSMCE1 NSMCE2 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
RBM22 SNW1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
FBXW7 NOTCH1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
TP53 MDM4 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7290688 19521340
TP53 MDM4 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7290688 19521340
EID3 NSMCE1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NSMCE1 NSMCE4A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
SFN TP53 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MDM4 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SGK1 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21620836 28850619 21147854 23431463
FBXW7 NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11425854 11461910 20571051 23331499 20823234 17909182 25344755 32792479 11585921 16713569 17646408 27229929 15546612
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HUWE1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 15989956 19918835 19960022 19590512
TP53 MDM4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16492744 18172009 21750655 20036872 21422812 17510313 9926934 18336191 19521340 20372076 10469568 20080970 22290440 21394211 23474762
MDM4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 74.0 1.0 Omnipath 25609649 18677113 28487147 24445145 30045945 20515689 26148237 22266850 11528400 19521340 21088494 16713569 15916963 9226370 12874296 21925390 16024788 25825738 24667498 16227609 24127580 8895579 20174603 18485870 12963717 15604276 25464845 12370303 10608892 23028042 25961923 26186194 17110929 22374672 26876197 17301054 23671280 21965653 17875722 22807444 10075736 19305137 17080083 29023092 27114532 20724842 10827196 19255450 24659749 28035068 23946421 20705607 19075013 21075307 12393902 11223036
NOTCH1 SNW1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 23331499 10713164 11404076 15546612
PIAS1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 15133049 10380882 20805487 11867732 16713569 11583632 11788578
TP53 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18281511 10101800 22427654 12640112 17404570 12447694 17361185
TP53 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20206173 17546054 18431400 21340684 20066118 20457558 20182602 11896572 6396087 14517281 21625211
TP53 SGK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9058378 18430410 19756449 8647846
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368