Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PPP1CB CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14592972 16467385
PPP1CC CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14592972 16467385
SLC25A11 CDK5R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EGR1 CDK5R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15289351
EGR1 LMTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15289351
NPT2B LMTK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LMTK2 PPP1CC â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RBM14 PARP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11443112 16713569
PPP1R2 PPP1CC â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8286865 10807923 003082200
EIF2S2 RPS29 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EIF2S1 RPS29 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PRKDC PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20085707 16794079 21575865 9398855
ABCE1 EIF2S1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
SSRP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
ABCE1 EIF2S2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
KLC1 KLC4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KLC1 KLC2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MYO6 LMTK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18429820 29467281 19855435 18029400
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
LMTK2 PP1G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 30344098 28330616 26496610 28065597 26186194 24366813 23080069 28514442 21382349
LMTK2 PP1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28065597 12393858
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PP1G PP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 30344098 28330616 26496610 26186194 24366813 28514442
CDK5 PPP1CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 010002200 11320080 8286802
PPP1R2 PPP1CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8286865 003082200 10807923
KIF5B KLC4 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
KIF5B KLC2 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
SSRP1 SUPT16H â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CDK5R1 CDK5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 23543736
PPP1CB PPP1R2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
KIF5C KLC1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CDK5 CDK5R1 â—¼   PHOSPHORYLATION ✅ - 0.94 0.94 Signor 18326489
KIF5B KLC1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PPP1CA PPP1R2 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
KLC2 KIF5C â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9624122 26344197
KLC4 KLC2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 30217970 22863883 26496610
PPP1CC PPP1R2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
ABCE1 RPS29 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PPP1CC PPP1R7 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP1CB PPP1R7 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP1CA PPP1R7 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CDK5 CDK5R1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP1CA CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9543386 14592972 11897663 16467385
CDK5 PARP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759
CDK5 CDK5R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11583627 23602568 15689152 11389014 17036052 25076872 21220307 15890360 16189514 23979715 26186194 17591690 17762160 14521924 20133653 22654103 28637746 12223541 23543736 18326489 28077789 17121855
CDK5 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12202491 9122166 17202132
CDK5 LMTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12832520 23331499 28580371 22220831
CDK5R1 LMTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22220831 23331499 12832520
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
PPP1CC EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 21622569 9023344 27629041 9694816 12941928
PPP1CA EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21622569 9694816 9023344 12941928
PPP1CB EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21622569 9694816 9023344 12941928
LMTK2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12202491 24120663 23331499 17283141 16785988 17202132 12393858 21996745 18250156 29764992 22220831
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
PPP1R2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 22321011 26186194 28330616 20826336 27173435 18250156 10807923
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368