SP1
|
STARD3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12802284
|
SP1
|
SCARB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10801817
12816880
|
SP1
|
CYP27A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11867220
|
SP1
|
CYP7A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9875228
|
SP1
|
TSPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17402746
21958735
|
SP1
|
PAX3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20435036
18314536
|
ABCG8
|
ABCG5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16870176
5218866
|
HP
|
APOA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19758344
7258755
|
VDAC2
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VDAC3
|
VDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP3
|
TSPO
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17402746
21958735
|
SP3
|
HP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12021177
12888570
|
SP3
|
LCAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9610763
|
SP3
|
CYP27A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11867220
|
WFS1
|
LCAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VDAC3
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
WFS1
|
VDAC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APOC2
|
LPL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10727238
11579204
|
WFS1
|
LPIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
WFS1
|
PLA2G12A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP3
|
SP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
15247906
11517158
10825178
16734381
9329821
12414801
12200149
23825960
|
VDAC3
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
LPIN3
|
LPIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
LPIN3
|
LPIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
VDAC1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
VDAC1
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31536960
22939629
29128334
|
APOA1
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28183703
7592581
19164805
|
APOA1
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10722751
24981860
3104518
|
LDLR
|
MYLIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
APOA1
|
APOC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15174051
11991719
|
LRP2
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11421580
7768901
16713569
|
VAPA
|
VDAC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
26344197
26496610
|
LRP2
|
APOH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
9727058
16713569
|
VAPA
|
VDAC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22939629
26344197
26496610
|
NPC1
|
NPC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20674861
27238017
|
VDAC2
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31536960
22939629
30021884
|
LRPAP1
|
SORT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
SP1
|
SP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
VAPA
|
VAPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
APOA1
|
LCAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
PLTP
|
APOA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
9469594
|
LDLR
|
APOB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24447298
12031600
|
APOA1
|
PLTP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11854286
9469594
|
LRP1
|
LRPAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
LDLR
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24447298
12036962
20030366
|
APOA1
|
ABCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12084722
30458687
27017521
|
VDAC1
|
VDAC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31536960
22939629
29128334
30021884
|
LRP1
|
APOE
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
2779654
11421580
20030366
15182176
|
SP1
|
LCAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9610763
|
SP1
|
CETP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12730302
10669650
|
SP3
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9329821
15247906
10825178
|
VAPA
|
VAPB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
19515777
16227268
9920726
26496610
33961781
26186194
34079125
|
PCSK9
|
LDLR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18250299
22081141
25613181
18753623
17435765
23085658
|
MYLIP
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
30896554
26666640
23382078
|
ABCG8
|
ABCG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12208867
16870176
27144356
|
LCAT
|
APOA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
4335615
15654758
16189514
1644835
10026251
10222237
1587806
17676061
3104518
|
SP3
|
ABCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15922656
10884428
|
SP3
|
PCYT1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12584202
10744779
|
NPC1
|
NPC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
LDLRAP1
|
LRP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
ABCG5
|
ABCG8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
LDLR
|
PCSK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
A2M
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10652313
1702392
12194978
19026743
|
LRPAP1
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
10747918
1718973
1374383
14596620
20030366
|
LRP2
|
LDLRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
14528014
23836931
7768901
8710919
8706697
|
SP3
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
21554857
12509426
9632663
10362515
19223508
15857802
20096088
16806531
15854045
15118068
9788252
12773549
16617124
11517158
12554796
9666093
15869407
12888570
11287330
15541732
8845379
16574784
8070411
|
SP1
|
APOC3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7640286
11802721
9012660
|
SP1
|
APOE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15670754
11229886
18467438
2188976
|
SP1
|
LDLR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
24358207
14568562
7836375
11250935
10894816
9610768
11792717
16647292
7597088
14998783
7627719
10841543
16303770
9271397
10224053
16449644
|
SP1
|
ACHE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
24315822
7829523
15576380
2677669
1846185
|
SP1
|
PCYT1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10216289
12794070
16484221
20096375
10744779
17384411
16157598
15247247
|
SP1
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11250933
11111087
15129808
10919277
|
SP1
|
APOA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22901716
11278817
10829013
15164326
15375792
11121483
23293065
|
APOE
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
12036960
24447298
31677479
20030366
12036962
15840700
11327878
|
PCSK9
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
22081141
29209441
17435765
25613181
23085658
18753623
18250299
|
APOB
|
LDLR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12031600
24447298
11986215
15840700
1132787812031600
11327878
|
HP
|
APOA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15533931
19758344
17824618
|
APOA1
|
ABCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
30458687
12084722
12869555
22271762
27100352
|
APOA1
|
LCAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
1587806
10222237
10026251
19860440
16189514
15654758
4335615
17676061
1644835
|
PTDSS1
|
SCARB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12016218
8999945
|