Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LRP6 KREMEN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20053636 18606139
DKK1 KREMEN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20053636 18606139
DKK1 LRP5 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 11516963 33961781 26186194 15035989
DKK1 LRP6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11448771 21984209 27322059 11357136 33961781 26186194 21944579 15035989
LRP5 DKK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19158955 18044981 17047023
CTNNB1 DKK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15592430 15592505
LRP5 KREMEN2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19158955 18044981 17047023
DKK1 LRP6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
DKK1 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 23331499 19339249 21071413 12527209 21944579 11448771 21984209 11357136 11516963 18988627 29925589
KREMEN2 LRP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12050670 29925589
LRP6 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 25088803 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
DKK1 KREMEN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 12050670 12527209 19101658 18786602 16307379
DKK1 LRP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19101658 11448771 18786602 16307379 11516963