Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
TNR1A KHNYN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TKT KHNYN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 TKT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24654937 26344197
UBC UBQLN2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ZCCHV KHNYN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 34695163 24981860 29395067 28514442
RBCK1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
KHNYN NEDD8 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
EXO1 KHNYN â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368