Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SOCS3 JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10421843 10064597
SOCS3 LIFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17312100
JAK1 CNTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12707266 7852997
LIF JAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12601009 15519241
JAK1 CNTFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12707266 7852997
LIFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11294841
CNTFR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11464862
JAK1 SOCS3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10707961 10373548
IL6RB LIFR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8999038 12047380
IL6RB CSEN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956
OSMR JAK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 10586060 33961781
IL6RB IL6RA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11238858 2788034
LIF IL6RB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12707269 16051226 14527405
PTN11 IL6RB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9388212 9794795 9195977 12403768 10777583 10946280
CNTF CNTFR â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CNTF LIFR â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IL6RA CNTF â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12643274 1281789
IL6RB IL6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14557255 7744001 11251120 18775332 12829785
OSMR IL6RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9188471 8999038 24501689
IL6RB CNTFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12707266 11285233
PTN11 SOCS3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12403768 10777583 17138568
IL6RB CNTF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12643274 16051226 18775332
ONCM LIFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8999038 1542794 16051226 1536831
LIFR CNTFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12707266 11285233 11943154
IL6RB ONCM â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 8999038 33961781 26186194 16051226
IL6 JAK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8134389 8272873 9382798
PTN11 JAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8995399 9794795 11036942 12270932 12403768
IL6RB JAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21220115 9388212 11742534 11468294
IL6RA IL6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14557255 9694899 7744001 2788034 18775332 11238858 8702737 12643274 28265003 12829785 9028955
SOCS3 IL6RB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24438103 32548823 12403768 10777583 10946280
LIFR CNTF â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 12643274 10207005 16051226 18775332
LIF LIFR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8999038 8662595 16051226 9852103 12601009
CNTF CNTFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7810882 10812968 18775332 8627290 20584990 7539796
JAK1 SOCS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 25682267 10950967 16459330 10707961 10373548
CNTF LIFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 18775332 16051226 10207005 12643274 10966616
CNTF CNTFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 10812968 18775332 20584990 7810882 8627290 8081242 7539796 10966616
JAK1 LIFR â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 11306493 19833085 21840487 22595692 24857661 7512720 7521688
JAK1 LIF â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 11306493 19833085 21840487 22595692 24857661 7512720 7521688
JAK1 IL6 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 LIF â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 11306493 19833085 21840487 22595692 24857661 7512720 7521688
JAK1 IL6 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
JAK1 LIFR â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 11306493 19833085 21840487 22595692 24857661 7512720 7521688
JAK1 IL6 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
OSMR JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10586060 23331499 15935618
LIF LIFR â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 11306493 19833085 21840487 22595692 24857661 7512720 7521688
LIF LIFR â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 11306493 19833085 21840487 22595692 24857661 7512720 7521688
LIF LIFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 19833085 7521688 23331499 24710148 12601009 11306493 9852103 24857661 7512720 16051226 9143707 9716487 8999038 10428964 21840487 22595692 26192618 8662595