Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ACKR3 CXCL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9618518 16107333
ESR1 ACKR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23352615 18414489
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
IL16 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10479680 9422780
ESR1 CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18563714
ESR1 CXCL12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16912174
ELAVL1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19151756
ELAVL1 IL13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18279945
ELAVL1 CXCL8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18650551
HSP90AA1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CEBPB HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880553 10440232
CEBPB HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18266962
HSP90AA1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18591668 21465483
HSP90AB1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TBK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FADD IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227629 23131831
IL1R2 IL1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16971486 0603545103
IL1A IL1R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16971486 0603545103
IL1A IL1R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2946959 8327496
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ESR1 MAPK12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16885352 22399296
TNF CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21887257 19287455
ESR1 CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20404154 17932106
IL10RA IL10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11485736 5214351
CXCR6 CXCL16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11060282 9166430
CCL3 CXCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9312096 11470772
CCL21 CCR7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8383238 7851893
BMP10 ACVRL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17068149 17311849
FADD FAS â—¼   COLOCALIZATION 2.0 0.8 intact 16498403 5218359
CHUK NFKBIA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12799363 23430059
IL1R1 IL1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221365 9062193
IFNGR1 IFNG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 376230 7617032
IFNAR1 IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18929502 23331499
ESR1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12603855 26790618
CEBPB FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7543095 11473033
FOS FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10903433
CASP8 TNFSF10 â—¼   COLOCALIZATION 2.0 0.8 intact 23678861 8429107
IL1B CASP8 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 1574116 22267217
CASP8 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CASP8 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
HSP90AB1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK IKBKB â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12799363 23430059
IL2RG IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
EBI3 IL12RB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22306691 12829785
FOS IL18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15543578 10975835
IFNE IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22410872 32196115
FOSB IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7989759 9171236
FOSL1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1737937 11385624
CEBPB CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7513199 21455770
IL10RB IFNL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
IL10RB IFNL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
CD70 CD27 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 17237405 19062317
CXCR4 CXCL14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23669361 8427967
CXCL14 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32239134 28360196
FOS BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19009553 18495116
HSP90AB1 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IFNE IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22410872 32196115
CEBPB DEFB4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15985221 11781391
CEBPB IL24 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10942517
CEBPB PRLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16651265 21670145
IL22 IL20RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17208301 23331499
ACVR2B ACVRL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
GSK3B FOSL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20154735
ESR1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9259323 8625613
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
PRL ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25193864 19524120
CXCL11 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22633458 15178708
ACVR2B ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
BMP8B ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10504300
ACVR2A ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9748228 8612709
BMPR1B ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
BMPR1B ACVR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
BMPR1A BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10712517
ACVR2B BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
BMPR1A ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
ACVR2B ACVR1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
BMP8B BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10504300
IFNLR1 IFNL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
IFNLR1 IFNL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
TRAF3IP2 IL17RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17035243 17277779
EDA EDA2R â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14656435 10484778
EPOR EPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
IL1RN IL1R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1828071 2139180
IL23A IL12B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCL1 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11470772 10910894
CCL18 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23951310 32103204
CCR3 CCL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12554737 9276730
CCR6 CCL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9169459 12149255
BMP6 AMHR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
CNTFR CLCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21715184 10966616
CCR2 CCL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12554737 9276730
CX3CR1 CX3CL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9024663 9390561
IL24 IFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18511292
IL1F10 IL1RL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26892022 22315422
IL36A IL1RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11466363 30452921
CCL25 CCR9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10229797 10640743
IL17C IL17RE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21993848 21993849
ACVR1 BMP7 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ACKR3 CXCR4 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
IL17F IL17RA â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ACVR1 BMPR2 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ESR1 FAS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
CSF2 CSF3R â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11468284 9187659
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
IFNA4 IFNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNA4 IFNA8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNA4 IFNA7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACVRL1 BMP10 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
GDF11 TGFBR1 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
IFNA5 IFNA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CCR5 CCL4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9334377 10477718 10498628 8663314 23597562 12427015 9468473
CSF3 CSF3R â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16492764 10364174
IFNA2 IFNA5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
BMPR2 BMP6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11401330 10504300
IFNA5 IFNA4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IFNL3 IL10RB â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IL21 IL21R â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IL1B IL1R2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NFKBIA IKBKG â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
IKBKG NFKBIA â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
TGFB2 TGFB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 11483955 33961781 11157754
CD70 CD27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 7479974 8186199 9862673 9767422 21917027 15723067 8120384 33961781 26186194 8580829
IL12B IL23R â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
IL17RA TRAF3IP2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
IFNL3 IFNLR1 â—¼   PHYSICAL_INTERACTION ✅ + 0.85 0.85 Signor 12469119
IL22RA1 IL22 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 18675809 6693914
CCR3 CCL7 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8642344 10733106
BMP7 ACVR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8006002 18070108 16189514
CCR4 CCL22 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9743322 9933589 9430724
CCR4 CCL5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 8573157 12270118
CCL23 CCR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9886417 9558365 10660125
ACVR2B TGFBR1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ACVR2B BMPR1A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
IKBKE TNF â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCL5 CCR3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
CCR1 CCL7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 8530354 7545673 9336350
CCR5 CCL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9334377 10477718 9169459 11700073 9468473
CXCL9 CXCR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9660793 11259614 12782716 9625760
CCR3 CCL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11449371 10733106 8642344 7622448 9289016
CCR1 CCL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11449371 12270118 8530354 7545673 14637022 11116158 7622448 9115216 9289016 10910894 9336350
IL16 CD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 7910967 16189514 1851800
EDAR EDA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11309369 11035039
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FAS FASLG â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CASP8 FASLG â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
ACVR2B BMP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CNTF CNTFR â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IFNA14 IFNA6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IL20RB IL22RA1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BMPR2 BMP7 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7644468 7791754
IL1R1 IL1B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7878046 9062193
IL15 IL2RG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 8178155 10903799 8568232 9371812
CD4 CXCR4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10816381 15660419 14592831
GDF5 BMPR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19229295 9525338
BMP4 BMPR2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IKBKG TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BMP2 BMPR1B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
TGFBR2 TGFB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8044119 21054789
CCR5 CD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10816381 30542158 15660419
BMPR2 ACVR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 7890683 28514442 7791754
BMPR2 BMP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28126904 12045205 7673243 7644468 8702914
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
IL15 IL2RG â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
BMPR1A GDF5 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ACVR2A BMPR1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
FADD TNFSF10 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
IL1RN IL1R1 â—¼   PHYSICAL_INTERACTION ✅ - 0.89 0.89 Signor 2876877
CASP3 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9367996 29752472
IKBKE TRAF3IP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23066157 21822257
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
FOS IL1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8688489
ESR1 CCL7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
CXCR1 CXCL6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1840701 3260265 9164944
CEBPB CCL4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20702408 19109189 24038085
CCR7 CCL19 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 11698286 17035340 19759904
CCR7 CCL19 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 11698286 17035340 19759904
CCL16 CCR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7679328 9207005 8048929
CCL16 CCR8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7679328 9207005 8048929
CCL16 CCR2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7679328 9207005 8048929
FOS CD40LG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11160303
CCR5 CCL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11449371 10477718 10488147 9334377 8663314 14637022 9207005 11116158 9289016
IKBKB NGF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8837778 11244088 8599092
CASP8 TNFSF10 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
TBK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10783893 21138416
IL2RG IL21R â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11418623 11016959 12093291
IL12A IL12RB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
IL12B IL12RB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
IL12RB1 IL12RB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
IFNK IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17208301 23331499 22410872
IL10RB IFNL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
IL10RB IFNLR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
IL10RB IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12483210 23331499 12974481
CSF1R CSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26235028 2408759 22483114 8355686 22153499 22902366
CSF1 CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16492764 23331499
CSF1 CSF2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10572088
CCR5 CXCR4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12429730 15660419 18632580
CEBPB CSF3R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20659895 10453008
CSF3 CSF2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10572088
IFNK IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17208301 23331499 22410872
IL12A IL12RB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
IL12B IL12RB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18389480 7638186 7528775
CEBPB ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 16651265 7651415 19652226 9817600
CEBPB CCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16864713
CEBPB CSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10855690
CEBPB IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11509602 24012417 11279072
IL24 IL20RA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12351624 22802649 11706020
IL20RB IL20 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11163236 22802649 12351624
ESR1 BMP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15040833 17574840 16232348
ESR1 CCL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 PRLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16705189 16651265 18414489
FOSL1 IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22253262 12929935 9488674
AMHR2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 14746809 16446785
GDF11 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12414726
ACVR2A ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12682303 9032295 8612709
FOSB IL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21931225 20927330 19665600
BMPR2 BMP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10880444 10712517 25938661 7791754
ACVR2B BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 17295905 16446785
CCR3 CCL11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8676064 10733106 9169459 9712872 9207005 8642344 25450766 8609214 23597562
EPOR EPO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9030560 29997244 9808045 17327410 9774108 26481148 15358619 10318834 8662939
IL23A IL12B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29997244 12023369 11114383 18680750
IL12B IL12A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10899108 10779781 7527811
IL17RA IL17C â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23834281 21993849 21993848
IL12A EBI3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22487722 18033300 9342359
IL24 IL20RB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12351624 22802649 11706020
CCL13 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10699158 23846739
CLCF1 CNTFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26858303 11285233 10966616 11294841
CCR10 CCL27 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10781587 10725696 10725697
CCR10 CCL28 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10781587 10725696 10725697
IL1RL2 IL36A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11466363 22315422 25673295
IL36RN IL1RL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20081871 20959797 24332029
DEFB4A CCR6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11934878 10521347 10914484
IL17RE IL17C â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23834281 21993849 21993848
BMPR1B GDF5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EPO EPOR â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
TNFSF10 FADD â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 10894160 5212774
FAS CASP8 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 11717445 5214823
CASP8 FAS â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 5219431 17159907
FAS CASP8 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 16498403 5218359
GDF2 ACVRL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.91 0.91 Signor 17068149
IL11 IL11RA â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CCL19 CCR7 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 9153236 9507024
TNFSF10 CASP8 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 10894160 5212774
TNFSF10 CASP8 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 8429107 23678861
BMP4 BMPR1A â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
IL23A IL23R â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CASP8 FAS â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
IL17A IL17RA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
IFNAR2 IFNW1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
IL20RA IL20RB â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
IL20 IL20RB â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PRL PRLR â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
CD40 CD40LG â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IL15RA IL2RG â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CSF3 CSF3R â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IFNAR1 IFNW1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IL20 IL20RA â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IFNL1 IFNLR1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
GH1 PRLR â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IL1R1 IL1RN â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
IL1R2 IL1RAP â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
ACVR2B GDF11 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
IL1B IL1R1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CCL20 CCR6 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 10488147 10498628 9169459 9223454 9294137
ACVR2A BMP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
ACVRL1 GDF2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
IL1RAP IL1RL1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
IFNAR1 IFNAR2 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
IL2RG IL2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16477002 8049354 11418623 8006584 10662798 22446627
IL12A IL12B â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
FASLG TNFRSF6B â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACVR2A BMP2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CSH1 CSH2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
FAS FADD â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219431 17159907
FAS FADD â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16498403 5218359
PRL PRLR â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10966654 9626554 22325776 23048206 7984244
CRLF2 TSLP â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
IFNA2 IFNAR1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CNTF CNTFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7810882 10812968 18775332 8627290 20584990 7539796
NFKBIA IKBKB â—¼   PHOSPHORYLATION ✅ 0.97 0.97 mint 8209688 16126728 506093200
BMPR1A BMP2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19804412 7261592
GH1 GHR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CCL5 CCR5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IFNA2 IFNAR2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IL1B IL1RAP â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IL12B IL23A â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CCL11 CCR3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
IL22 IL22RA1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CCR5 CD4 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
TGFBR1 TGFBR2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
IKBKG IKBKB â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219009 16938294
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
CASP8 FADD â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 5219431 17159907
TNFRSF11A TNFSF11 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BMP2 BMPR1A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
FADD CASP8 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21785459 23142077 21988832 23972990 17290218 24098568 14681455 20103630 33469115 18485876 22274400 22864571 25043603 27560715 25939870 29795330 19524512 17159907 30561431 27552911 19176810 15659383 9343261 22179575 22173242 25911380 27321185 8681376 15280356 21737330 26437781 31046799 21458669 12702723 11717445 21737329 19060883 21525013 23429285 20448643 12107169 17047155 9228018 12887920 29497034 12911633 14612908 23955153 33961781 20829884 26972597 21620750
IKBKG NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CHUK NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
IKBKB NFKBIA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CXCL12 ACKR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23396314 20956518 24218476 16107333 22633458 20161793
CXCL11 ACKR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 29386406 29180449 27875312 24218476 22633458 16940167 20161793
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP3 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9367996 11741536
CXCL12 CXCR4 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CXCL12 CXCR4 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CEBPB CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17656649 19962993 23098564 25453873
CXCL12 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24023874 10233851 10699158 11859124 22633458 18648536 18448868 8752280 30476826 12714578 16725153 9712844 8752281 9551924 21757744 19837984 25495026 26582643 16626895
CXCL12 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9660793
ELAVL1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12963828 18519672
CEBPB GDF15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24086573 20110283
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
IKBKE NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10783893 18794072 8657102 8601309 15939554 12138192 10329681 10882136 9721103 12403772 21171089 16888014 15879144 20717897 16007147 7796813 11815618 10421793 25133483 21872579 10398585 16199137
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
NFKBIA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
CSF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10426994 11015446 11280761 11460167 11777960 11907067 12193690 12907458 14660645 15536084 16713974 17301840 18264787 20805416 21133840 21232017 21765015 22869907 24030977 24699077 24958845
FADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IL2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10807786 11280761 11460167 14660645 15289500 15563472 17301840 1825141 18264787 18758473 19528259 21133840 21232017 22224781 23650441 24699077 24958845 26755705 2965306 6164929 9625766
IKBKG NFKBIA â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IL13 IKBKG â—¼   DOWN_REGULATES ✅ - 20.0 1.0 ACSN 11280761 11460167 12223527 12401408 14610620 14657224 14660645 15099563 17301840 18250477 18264787 18451175 20184663 21097505 21133840 21232017 24699077 24958845 26755705 9535722
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
IKBKG NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 17145710 7862124 11087742 10602462 16818647 8657102 16965765 22435544 11064457 24369075 10880512 7739562 14743216 16319058 7878466 16126728 10329646 15836773 16177806 21217772 16153868 10195894 12514169 18617513 15371334 16493424 17706453 15145317 10723801 15870263 7796813 17468758 16603398 17965022 11830587
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
IL15 IL1A â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
IL1A IL1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25241761 16971486 7878046 1833184 9862719 23395675 78780467878046
IL1A IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 29469592946959 8142597 19479203 7692435 9565970 7775431 2946959 17507369 7964161
IL1A IL1RAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9820540 9862719 7775431 17507369
MAPK1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 21980398 19443782 17570479 19413330 19723873 15367685
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
MAPK1 IL16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14768064
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 24342355 17290218
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
TNF FADD â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF FADD â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
IL15 TNF â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
TNF CXCL1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
IL6R TNF â—¼   DOWN_REGULATES ✅ - 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
TNF CCR2 â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10623817 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
FOS TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19285436 2506186 16834785 22322974 10837498 12057991 9030359 25567680 19026727
CEBPB TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 10775602 21059644 9831247 26114754 19530226 20220144 9566900 10748079 19489038 8726660 10754326 19109189 10838190 14514692 24012417 12184911 23971673 23590297 14976147 16850160 10629048 22074460 15850785 7929820 10887174
TNF NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19053972 24083678 25215581 29088783 24386331 25888769 20460401 16866128 19934328 9363938 24349153
CCL7 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 14991608 12381680 9115216 10699158 11994538 7545673 22633458 9336350 8530354
CCL7 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8642344 10733106 10699158 22633458
CCL7 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9276730 22633458 9115216 10699158 9346309 9195948 9312096 12554737 9336350 7759884 8530354
CCL7 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 10477718 16298345 10699158 22633458 10477710
CCL7 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10706668 9364936
CCL7 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9660793
CCL2 CCR2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 10623817 15032599 17681149 19915063 23527025 23567181 23943801 24531940 27216177
CCL2 CCR2 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 10623817 15032599 17681149 19915063 23527025 23567181 23943801 24531940 27216177
TGFBR1 CCL2 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
CSF1 CCL2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11306493 15749884 16713974 17404308 20547845 24669294
TGFBR2 CCL2 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
CEBPB CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17180354 10748205 20019816 12145301 16784777 17390372 18649942 20730378 19026986 15710476
FOS CCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18024959 18443042 14752027 8063765 12667961 17424890 7602115 9558097 16206198 19404962
CCL2 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 10770925 10488147 10699158 22633458 9169459 11470772 28389721 9336350 8530354 15629146 11310855 9276730 20219869 9115216 9346309 9312096 9837883 10529171 15207250 9287323 12554737 7759884
CCL2 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9364936 10706668
CCL2 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8631787 7679328 76793288631787 9115216 10699158
CCL2 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8642344
CCL2 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10477718 16298345 1629834510477710
CCL2 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17160712 16421945
CXCL8 CXCR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555778 18633355 18980965 21328342 21847358 24406209 25922287 26201938 26548401 27557510
CXCL8 CXCR1 â—¼   PROTEIN_INTERACTION 14.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555778 18633355 18980965 21328342 21847358 24406209 25922287 26201938 26548401 27557510
CXCL2 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8702798 9260277 16189514 1379593 12964882
CXCL6 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8702798 10699158 9485196 16189514 9692902 22633458 12964882 10593335
CXCL5 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8702798 10699158 16189514 9692902 12964882 9485196
CXCL8 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 8702798 8137938 9195914 10699158 1840701 12628493 10188995 15946947 22262769 8550564 9553055 1379593 8662882 8245475 10368283 9485196 8940121 15282370 11350788 9725262 10206993
CXCL1 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8702798 9195914 10699158 16189514 1379593 12964882
CXCL3 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 129648828702798 8702798 16189514 12964882
CSF2 CXCL1 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10426994 11015446 11280761 11460167 11777960 11907067 12193690 12907458 14660645 15536084 16713974 17301840 18264787 20805416 21133840 21232017 21765015 22869907 24030977 24699077 24958845
CXCL1 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 7592830 8702798 9195914 10699158 12628493 22633458 10188995 12549928 8550564 28389721 16189514 1379593 8662882 9126332 10216072 24218476 8940121
CSH1 PRLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 10966654
IL10 IL10RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10 IL10RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
FOS IL10 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 9064320
CSF1 IL10 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11306493 15749884 16713974 17404308 20547845 24669294
IFNG IL10 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
CEBPB IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24715531 17525287 12493739 12847250 16413748
IL10 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17208301 23331499 9312047 12974481 20462497 11485736 10347215 12513909 11035029
IL10 IL10RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 17208301 11717514 7759550 23331499 21071413 12974481 8897595 20462497 15837194 10347215 9568901 19161426 8120391 12513909 26260587 10788470 11591769 11485736 8248239 10231374
BMP7 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9748228 7790373 12667445
BMP7 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11282024 8006002 31619522 122976748006002 16189514 12297674
BMP7 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15621726 106311828605097 8605097 10631182
BMP7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18342887 16446785 7791754 7644468
BMP7 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9748228 23331499 16446785
BMP7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16189514 7791754 12297674 8605097
CXCL16 CXCR6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 11017100 14625285 11290797 22633458
CXCL5 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8702798 10699158 16189514 9692902 22633458 9485196
TGFBR1 CCL3 â—¼   DOWN_REGULATES ✅ - 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
TGFBR2 CCL3 â—¼   DOWN_REGULATES ✅ - 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
CEBPB CCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20702408 19109189 24038085 9885903
CCL3 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 11170631 10734056 10488147 10699158 7545673 10202040 22633458 10498628 9169459 9336350 10910894 8530354 23765404 9687537 9207005 20219869 9115216 9624164 10660125 7622448 12381680
CCL3 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8573157
CCL3 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24218476 7594543 7622448
CCL3 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 11170631 16298345 10477718 23765404 15075201 9468473 20219869 9169459 11700073 10699158 9334377 9790730 22633458 12964882
CCL21 CCR7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11970971 10488147 9507024 10699158 16713569 22633458 22221265 9585422
CCL21 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26888559 11907075
CCL21 ACKR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10706668 23341447 16713569 22633458
BMP10 ACVRL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17068149
BMP10 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
BMP10 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16049014
BMP10 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15621726 16049014
BMP10 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30246251 30246252 27252362 31127068
BMP10 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15621726 31127068 16049014
CXCL9 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9660793 12782716 15761110 9625760 12750173 10699158 11259614 12884299
CXCL9 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458
IFNA6 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA6 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
CCL4 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 7594543 12381680 10699158 7545673 10910894 8530354
CCL4 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7622448
CCL4 CCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10699158 9521068
CCL4 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 10498628 16298345 8663314 10477718 9468473 20219869 23597562 10699158 9334377 9790730 16467191 22633458 12427015 12964882
IFNA14 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA14 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
CCL19 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10706668
CCL19 ACKR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10706668 23341447 16189514 22633458
CCL19 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CCL19 CCR7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10512740 9507024 15546958 10699158 9153236 24218476 22633458 11342595 16904643
CCL22 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9933589 9430724 29637711 10699158 22633458 9743322
CCL17 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10498628 10488147 9169459 9430724 29637711 10699158 9169480 10540332 22633458
CCL5 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8573157 12270118
CNTF CNTFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 10812968 18775332 20584990 7810882 8627290 8081242 7539796 10966616
CASP8 FADD â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
FADD FASLG â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FADD CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD FAS â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FADD CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD FAS â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FADD FASLG â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FAS FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 22864571 8521815 11717445 21713032 16762833 23606538 8967952 20935634 7538907 21803845 9325248 19118384 12721308 21959933 18328427 16189514 25563855 10196099 17159907 27321185 26186194 25241761 9880544 16498403 21625644 9082980 12107169 15659383 15993755 21382479 7536190 11464215 26942442 11035039 15725726 16410793
FADD CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 82.0 1.0 Omnipath 22864571 17145710 11717445 19524512 34591612 15280356 17047155 27552911 12911633 25043603 21458669 11788820 19176810 21525013 21988832 22179575 25939870 12702723 21737330 21741934 26437781 25911380 9228018 21785459 20829884 23972990 21620750 12220669 9774341 17159907 10521396 27321185 17290218 27560715 20103630 24098568 20203691 14612908 8681377 18485876 12107169 15659383 22421964 20448643 9343261 20125124 8681376 12887920 19060883 21737329 23142077 22173242 26972597 22274400 19935698 16410793
IKBKB NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
TBK1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 10783893 9721103 16007147 12138192 7796813 12403772 10990461 10421793 11815618 8657102 10398585 8601309
CHUK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 113.0 1.0 Omnipath 17145710 15922746 11087742 18074035 12626540 11527961 9244310 11809792 15836773 16177806 9721103 18501560 11923072 17706453 9509763 10723801 11858955 10421793 25133483 10398585 9346484 9346241 21765415 8657102 16737960 9315679 9252186 21490922 16219905 14743216 20484017 10329646 18922877 10882136 16153868 10195894 14751757 16007147 7796813 17053167 9632633 15856023 17965022 10783893 10602462 23602409 27682876 10469655 16965765 15084594 16493072 11095741 12138192 10723127 15210742 10329681 7878466 26930276 9914500 9520446 12514169 12403772 10527519 15145317 16493424 9135156 16023083 12637324 10593898 14636585 9214631 7862124 10074115 15389589 12486103 9891086 8601309 10880512 7739562 16286467 17379600 23109003 9689078 15371334 10733566 29145629 11042193 23970940 10085062 17468758
IKBKB NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 164.0 1.0 Omnipath 18593939 17145710 18375836 11087742 16793322 11527961 28086098 21232017 12429743 21423167 17693123 21399639 15836773 16177806 9721103 29139553 9271416 17561400 11923072 10889159 17706453 10723801 12791687 11858955 22037600 16365431 10421793 25133483 10398585 9346484 9346241 11158290 18539148 23328071 15574499 21765415 16818647 8657102 18202307 16737960 9315679 21490922 9252186 20001801 15919917 16495515 11368781 16291755 24386391 14743216 25759022 10329646 10882136 16153868 10195894 14751757 18981174 10807933 16007147 7796813 9632633 15856023 17965022 25753787 10783893 10602462 27682876 16965765 15084594 19196987 17322026 12138192 10723127 15210742 16319058 15217903 15218526 7878466 9914500 17367806 9520446 15214841 16846590 12514169 18657515 12403772 10527519 15145317 16888014 16493424 17047224 9135156 15024091 16023083 10593898 14636585 22579987 9214631 24911653 7862124 10320352 16970925 23707515 9346485 12949498 17363905 12486103 9891086 8601309 10880512 7739562 16286467 23109003 9689078 25595906 15371334 16285893 11356195 29145629 23970940 10085062 11815618 17468758 17615396 24586253 17072322
CXCL8 CXCR2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555777 18555778 18633355 18980965 21328342 21847358 23869868 24406209 25922287 26201938 27557510
CXCL8 CXCR2 â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555777 18555778 18633355 18980965 21328342 21847358 23869868 24406209 25922287 26201938 27557510
CXCL6 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8702798 9485196 16189514 9692902 22633458 12964882 10593335
CXCL3 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8702798 10699158 16189514 22633458
CXCL2 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8940121 8702798 9260277 8550564 10699158 16189514 1379593 22633458 10188995 12964882
CXCL8 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 7592830 8702798 22904195 9195914 10699158 7559482 12628493 23597562 10188995 15946947 8626516 8550564 9553055 1379593 8662882 19190236 8245475 9126332 10216072 1891716 9485196 8940121 15282370 9464567 11350788 11511101 9725262 10206993
CCL16 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22633458 11470772
CCL16 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22633458 11470772
CCL16 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11470772 22633458 10910894
CCL16 CCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22633458 10910894
CD40LG CD40 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD40 â—¼   PROTEIN_INTERACTION 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG CD70 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD40LG IL2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11581322 15034038 17200410 17371980 23125331 8760829
CD40LG CD40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1280226 1374165 19426221 7516405 11163401 7543281 12324477 10647992 17183360
TGFB1 TGFBR2 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 TGFBR1 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR2 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 TGFBR1 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR2 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFBR2 CCL5 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
TGFBR2 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
IL18 TGFBR2 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 10679398 11592085 14504095 14662834 15099563 15802534 26885855 27048821 27066895 9469432
IL15 TGFBR2 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
TGFB2 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8106553 1310899 23331499 21071413 12729750 16446785 12809600 11157754
TGFB1 TGFBR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 122.0 1.0 Omnipath 1310899 22874531 8047140 11279127 22710166 7878020 16424049 17673906 24132110 18922473 22943793 12729750 16446785 20519943 7706250 15761153 7594497 15548370 15761148 15265520 19010789 26194464 7852346 12717440 17768418 19050695 11133108 14557817 11278410 19920116 22949611 22703233 23331499 23070005 20060931 17070508 21614932 1333888 10716993 16572188 20860622 11323414 21900405 12724770 8106553 23034983 26192618 2871107 12809600 11382746 21372296 20538542 16200688 11792802 26201938 24403530 15099563 11013220 17979848 21054789 23784029 15003992 20644162 8515656 7935686 11157754 20856203 18382895 15282297 18855897 9865696 21441952 10678166 16127449 21041659 10026191 22315516 12767520 17404308 19732719 20616810 21071413 17934056 12738796 18423981 21098712 19747910 9311995 15034927 11274345 12154066 18758450 24336330 21278795 26966341 9261125 16474430 15653932 18490733 8242742 19038247 19109155
TGFBR2 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 7774578 9463378 19556242 8047140 23868260 18243111 7890683 10026191 23331499 8576253 21071413 7878020 21791611 10716993 18988627 11278251 19758997 25825445 22802914 16446785 11483955 8947046 11323414 11124802 15221015 11102446 11387212 12809600 7566156 26194464
IL1R1 IL1RAP â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11274345 12620219 12682231 14660645 16878026 17704786 17942936 18977329 19104081 19161412 23202296 23681101 23811849 24727385
IL1R1 IL1RAP â—¼   PROTEIN_INTERACTION 14.0 1.0 ACSN 11274345 12620219 12682231 14660645 16878026 17704786 17942936 18977329 19104081 19161412 23202296 23681101 23811849 24727385
IL1RAP IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15044087 23331499 15866876 9430229 10854325 11756486 9371760 7775431 12530978 17507369
IL1B IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 17145710 23331499 8142597 9062193 7878046 9820540 7775431 2946959 24166242 9625767
IL1RN IL1R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 20959797 17145710 8142597 2876877 24332029 7589429 11641511 9062194
IFNG IFNGR1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNGR1 IFNGR2 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 22003200 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNGR1 IFNGR2 â—¼   SHARES_COMPLEX 42.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 22003200 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 16110316 12915721 12438563 7514165 15530433 23331499 16237089 23898330 9111318 15143187 16467876 10986460 18988627 1396683 8550631 20304997 11250200 10860730 12165521 29145629 10811850 7617032 18591661 8631301 7615558 7510216 7673114
IFNG IFNGR2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IFNGR2 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10485906 11489965 11579131 11777960 11867689 11870632 11964313 12413632 12811837 12818165 14607900 14610620 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 17683974 1825141 18272812 19833085 20038811 20406969 20819927 21149606 21411734 21840487 24091328 24658051 26755705 27216177 2965306 6425450 7512720 7521688 9834059 9864217
IFNG IL18RAP â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IFNG IL18R1 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
FOS IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19285436 16713974 7759501 8756632 12842891 12432566
CEBPB IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10995751 15878863 16331681 17556653 19521987 11312260 11009091 8634139
IFNG IFNGR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 12915721 7673114 7514165 12438563 15530433 23331499 16237089 9111318 15143187 16467876 10986460 18988627 1396683 8550631 29145629 10811850 7617032 18591661 8631301 7615558 7510216 20304997
TGFBR1 CCL5 â—¼   ENZYMATIC_REACTION ✅ 44.0 1.0 ACSN 11279127 11792802 12809600 14557817 15003992 15099563 15265520 15653932 16127449 16424049 16474430 16572188 17070508 17404308 17768418 17934056 17979848 18423981 18490733 19038247 19109155 19732719 19747910 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 22703233 22874531 23034983 23784029 24132110 24336330 26201938 26966341 2871107 7594497 8515656
CEBPB CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11937564 11413310 12388374 16239564
CCL5 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CCL5 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10734056 7622448 8642344 22633458 10733106 10699158 9289016
CCL5 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10734056 7622448 14637022 22633458 9115216 9624164 10699158 11116158 12270118 7545673 9289016 9336350 10910894 8530354
CCL5 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 16298345 10488147 28381538 10699158 22633458 9289016 12213786 8663314 11449371 10318947 12964882 25923671 9207005 23480650 11116158 10477718 14637022 9334377 9790730
CCL26 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 16102831 10488147 15207250 10699158 16339911 22633458
CCL26 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15207250 12689946 22633458
CCL26 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22633458 15039444
CCL26 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22633458 29637711 15039444
CCL26 CX3CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22633458 20974991 29637711
TGFB1 TGFBR1 â—¼   PHYSICAL_INTERACTION 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR1 â—¼   SHARES_COMPLEX 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
FOS TGFB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 15067049 15749884 16243976 16327802 16393692 16394015 16413922 16713974 17404308 17485448 19667062 20547845 21372296 21385848 22634314 23390297 23430059 9064320
TGFB1 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 75.0 1.0 ACSN 10678166 11013220 11133108 11274345 11278410 11279127 11792802 12154066 12717440 12724770 12738796 12767520 12809600 14557817 15003992 15099563 15265520 15282297 15548370 15653932 15761148 15761153 16127449 16200688 16424049 16474430 16572188 17070508 17404308 17673906 17768418 17934056 17979848 18423981 18490733 18758450 18855897 18922473 19010789 19038247 19050695 19109155 19732719 19747910 19920116 20060931 20519943 20538542 20616810 20644162 21041659 21098712 21278795 21372296 21614932 21900405 22315516 22703233 22710166 22874531 22943793 22949611 23034983 23070005 23784029 24132110 24336330 24403530 26201938 26966341 2871107 7594497 8515656 9311995 9865696
TGFB1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 22326956 10187774 7852346 22703233 12809600 7706250 11323414 8047140 8235612 26194464
TGFB2 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22326956 10187774 7608141 11157750 12809600 11157754
GDF9 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14684852 14514671 27252362
TGFBR1 ACVRL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 14580334 18333754
FOS CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11973337 18317936 12218154 22095787 12748173 10969814 15005855 17586662 16818736 24048734 14686613 16846747 15057743 15615716 8999951 25567680 19173296
ESR1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15208657 16029657 19440537 14991571 18669446 17932106
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
FASLG FAS â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22075988 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
FASLG FAS â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22075988 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9184224 9217161 9488730 9759866
CEBPB FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12496392
FASLG FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 17145710 8521815 9126929 1375228 1713127 14965271 21803845 9039262 11239407 25241761 9228058 15659383 12753742 7505205 12887920 15725726
FASLG TNFRSF6B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 14697332 9872321 11239407 10318773 11994433
FOS NGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8473354 2111020 2849107 9221899 8717334
TNFSF10 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10894161 27821809 23678861
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
IL2 IL2RG â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL15RA â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IL2RG IL15 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IL2RG IL21 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
IL2 IL2RG â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL15RA â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IL2RG IL21 â—¼   SHARES_COMPLEX 15.0 1.0 ACSN 10426994 11907067 12244150 12811837 15536084 16081783 16713974 16785506 19833085 20856220 21840487 23124025 24751819 7512720 7521688
IL2RG IL15 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IL2RG IL18 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL2RG IL23A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL21 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11418623
IL2 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 15265897 16477002 10807786 19528259 19833085 7521688 17371980 8049354 15563472 18758473 10662798 15289500 23331499 26755705 8683106 23180781 12095053 11418623 6164929 9625766 24829413 1825141 8006584 16799562 7829965 8568232 10820393 7512720 23650441 20856220 7681595 10849428 22224781 1631559 16212621 21840487 26192618 2965306 8260650 23124025
IL15 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8568232 9371812 15265897 1526589 10903799 8026467 19710453 11418623 16189514 8178155 78568232
CSF2 CSF2RB â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2RB CSF2RA â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2 CSF2RB â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2RB CSF2RA â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2 CSF2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1702217 2645577 18692472 8278375 2828352 7957082
IFNAR2 IL15 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR1 IL15 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IL15 IL15RA â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IL15 IL15RA â—¼   PROTEIN_INTERACTION 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
IFNAR2 IL15 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR1 IL15 â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR2 IL15 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR1 IL15 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IL15 IL18R1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
IL15 IL18RAP â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
IL15 IL12RB2 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
IL15 IL2 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10426994 10952726 11907067 14607946 15536084 16713974 17398124 17459805 19913445 20007590 21307131 25582338 7523571
IL15 IL15RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17709786 17145710 23331499 15265897 7641685 10903799 19710453 8530383 16284400
IL12RB2 IL12RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10807786 11867689 12244147 12372421 14610620 15546391 19833085 20406969 21042762 21115385 22077060 24091328 24204259 27216177 7543512 8683106 8700208 9834059
IL12RB2 IL12RB1 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10807786 11867689 12244147 12372421 14610620 15546391 19833085 20406969 21042762 21115385 22077060 24091328 24204259 27216177 7543512 8683106 8700208 9834059
IL2 IL12RB2 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10807786 11280761 11460167 14660645 15289500 15563472 17301840 1825141 18264787 18758473 19528259 21133840 21232017 22224781 23650441 24699077 24958845 26755705 2965306 6164929 9625766
IL21 IL12RB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12244150 16081783 16785506 24751819
IL12A IL12RB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11086056 943050 8943050
IL12B IL12RB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11086056 8943050 1108605611940480 11940489
IL1B IL12RB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10198225 7528775 9038232 8943050 9454765 7594594
IL18 IL18RAP â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IL18 IL18R1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IL18 IL18RAP â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IL18 IL18R1 â—¼   SHARES_COMPLEX 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IL13 IL18 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 7512720 7521688 7543512 9535722
IL13RA1 IL18 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20856220 21115385 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
IL18 CCR7 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10679398 11592085 14504095 14662834 15099563 15802534 26885855 27048821 27066895 9469432
IL18 IL18RAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9792649
IL18 IL18R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25261253 9792649 12096920 11046021 9325300
IL18RAP IL18R1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IL18RAP IL18R1 â—¼   PROTEIN_INTERACTION 18.0 1.0 ACSN 10679398 11274345 11592085 12620219 12682231 14504095 14660645 14662834 15099563 15802534 16878026 17704786 23681101 23811849 26885855 27048821 27066895 9469432
IL21 IL18RAP â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12244150 16081783 16785506 24751819
IFNB1 IFNAR2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15312780 9121453 10395669 9334213 15778442 12842042 17969444
IFNAR2 IL15RA â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR2 IFNAR1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
IFNAR2 IL15RA â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR2 IFNAR1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
IFNAR2 IL15RA â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNA5 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10395669
IFNA4 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNW1 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11278538 21854986
IFNA2 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10395669 10339405 21854986 18027911 10984492 17001036 11888273
IFNA7 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA10 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNB1 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 8181059 10395669 7623815 11278538 1127853810395660
IFNA13 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 8181059 10395669 11278538 11698684 21856167
IFNA16 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA17 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7623815 21856167
IFNA21 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA8 IFNAR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10395669 8969169
IL2 IL12RB1 â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10807786 11280761 11460167 14660645 15289500 15563472 17301840 1825141 18264787 18758473 19528259 21133840 21232017 22224781 23650441 24699077 24958845 26755705 2965306 6164929 9625766
IL2 LTA â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10807786 11280761 11460167 14660645 15289500 15563472 17301840 1825141 18264787 18758473 19528259 21133840 21232017 22224781 23650441 24699077 24958845 26755705 2965306 6164929 9625766
FOS IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20557936 8893011 11260070 11685114 8397339 1737937 9605137 9590239 11262396 7989759 1916630 8473495 10601992 8114694 22474330 18725523 9233628 11385624 2518655 15170389 8468462 7565732 12432566 8660843 7739550 1305903 20680391 19181930
IL13 IL13RA2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26755705 9535722
IL13 IL13RA1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 7512720 7521688 7543512 9535722
IL13 IL13RA2 â—¼   PROTEIN_INTERACTION 11.0 1.0 ACSN 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26755705 9535722
IL13 IL13RA1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 7512720 7521688 7543512 9535722
IL13 IL23A â—¼   DOWN_REGULATES ✅ - 32.0 1.0 ACSN 10485906 11867689 12223527 12401408 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 7512720 7521688 7543512 9535722
IL13 IL13RA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 18451175 17485448 18250477 20184663 19833085 7521688 26755705 23331499 12704343 17404308 15099563 23180781 24030977 21469115 11867689 1270434311278620 23390297 10485906 20406969 20856220 20510870 7512720 11278629 8910586 12401408 21840487 26192618 21097505 20223216 9013879 18243101 14657224 9535722 24091328 27216177 23124025 14610620 16413922 7543512 21115385 16243976 12223527
IL13 IL13RA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 18451175 18250477 20184663 27629921 26755705 23331499 12704343 26471366 15099563 23180781 1270434311003390 23972995 12401408 11003391 14985454 26192618 21097505 20223216 14657224 9535722 14610620 12223527 8663118
CXCL10 CXCR3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 18514095 18922917 22798340 23567181
CXCL10 CXCR3 â—¼   PROTEIN_INTERACTION 4.0 1.0 ACSN 18514095 18922917 22798340 23567181
CXCL10 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458
CXCL10 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 9660793 12571234 10233762 9625760 15761110 12750173 10699158 9064356 16189514 12884299
CSF2 CSF2RA â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
CSF2 CSF2RA â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
FOS CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 1900839 8135780 11509589 9028942 12432566 7579683 8631792 9862439
CSF2 CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 16720384 11091218 11468284 7691413 16492764 9187659
CSF2 CSF2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 10753826 8910448 11777960 27396825 12393492 19833085 10572088 22323450 23331499 22869907 9211889 24030977 11306493 11867689 9187659 11015446 1702217 2645577 20406969 23046136 20805416 2828352 7957082 18551128 26192618 18692472 21765015 24091328 27216177 2555171 14610620 12811837
IL10RB IL20RA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20462497 16982608 14764663 23704922 7543512
IL10RB IL10RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL10RB IL10RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IL22 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17208301 23331499 10875937 15120653 18509351 12513909 29608910
IFNL2 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL1 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL3 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IL13RA1 IL23A â—¼   DOWN_REGULATES ✅ - 31.0 1.0 ACSN 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20856220 21115385 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 7543512 9834059
CSF1 CSF1R â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 10705574 11306493 20644254 24669294
CSF1 CSF1R â—¼   PROTEIN_INTERACTION 4.0 1.0 ACSN 10705574 11306493 20644254 24669294
CSF1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7883784 8355686 1702217 22483114 22902366 2408759 26235028 22153499 24890514 26095744
IL1B IL1RAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9820540 7775431 20802483
CD40 CD70 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
CD70 CD27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8120384 21917027 26697006 7479974 9862673 8580829 12324477 8186199 9767422 15723067
IL16 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10438516 1851800 7910967 16189514 7615501
CD4 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 10816381 29637711
FOS IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7679081 20463008 7935377 14686613
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
IL1B IL1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 8332913 7878046 1833184 20802483
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
CEBPB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15860545 18180320 21292824 12773552 10531366
FOS IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19285436 15187114 15270850 14688340 25567680
FOS FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8446579 13679379 17371847 15514944
TBK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10783893 21903422 21138416 10195894 14743216 16207722 10022904 14560022
IL22 IL10RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10875937
CSF3 CSF3R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10537111 10364174 15676205 16492764
CEBPB CSF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26114754 7513199 21455770 12355443
IL21 IL18R1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12244150 16081783 16785506 24751819
IFNB1 IFNAR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15312780 8943354 18508557 15449939 17969444 16171819
IFNAR1 IL15RA â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR1 IL15RA â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNAR1 IL15RA â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10820393 11207245 11698286 11964292 12811837 14607946 14610620 14764699 15864272 16212621 16815076 17398124 17459805 17513775 19833085 19913445 20007590 20856220 21115385 21307131 21840487 21930765 21930769 23124025 24829413 25582338 7512720 7521688 7523571 7543512
IFNA13 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 7932753 23331499 8181059 11698684 21856167
IFNB1 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 8181059 1834641 10049744 7592797 7623815 11278538 18988627 29311663 112785381834641
IFNA7 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA4 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA10 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA16 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA2 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7592797 9334213 1834641
IFNA17 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7623815 21856167
IFNA21 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IFNA8 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7592797 21856167
IFNW1 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1834641 11278538
IFNA5 IFNAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21856167
IL21 IL21R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 21071413 11418623 18988627 1141862311418620 16424177
IL12A IL12RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 11086056 7911493 11114383 12023369 8943050 7527811
IL12B IL12RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11086056 7911493 7843232 8943050 7527811
IL23A IL12RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 23331499 11114383 12023369 12671732 18988627
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB TNFSF11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20225273 25811130
CEBPB PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10455153 15479564 10649437 24248464 16227626
CEBPB GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17129742 12213825 15860545 20228168 11414683 18180320 21292824 17110376 10531366
GSK3B CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22369944 22355693 16055922 17601773 15985551 22080951 23046544 17570479 15985552 19940121
IL19 IL20RA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11196675 14580208 12351624 22802649
IL24 IL20RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17208301 23331499 1297448111706020 12974481 11706020
IL20 IL20RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17208301 23331499 12974481 12351624 11163236 22802649 14580208
IL19 IL20RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17208301 1297448111564760 23331499 11564763 12974481 18988627
IL20 IL20RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17208301 23331499 12974481 12351624 11163236 22802649 22232181 14580208
IL20 IL22RA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17208301 23331499 12974481 11163236
GDF2 ACVRL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17068149 25237187
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
ESR1 FOSB â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 25542856 18219272 3677090 20219941 23145106 1630819 3045126 15514030 24854081 22265404 17013392 21835891 9671459 21940756
ESR1 FOSL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22514284 20034404
ESR1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 3481434 9259323 7649480 18022314 2082192 10830306
CCL13 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10477718 9790730
CCL3L1 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11170631 10364178 10477718 16298345 11734558 11449371 11700073 9790730 22633458 12964882
CCL8 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10477718 9468473 10699158 9790730 22633458 12964882
CCL14 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16298345 20483925 22633458 11085751 12964882
CCL11 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10477718 9468473 10699158 9790730 11264152 22633458 12964882
TSLP CRLF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 29145629 11418668 23331499 22915648 10570284 26198769 10881176 10974032 18988627
PRL PRLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 10585417 23048206 2558309 23192981 22325776 23331499 15082796 18988627 9626554 7984244 18253483 10966654 21889455 18467331 11356126 20053995 16546209 29145629 9175708 24243840
AMH ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14656470
BMPR2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 21071413 16446785 7791754 7890683
BMP6 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12297674
BMP2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8006002 28977600
GDF2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27252362 19996292
BMP4 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7811286 8702914 11282024 8006002
GDF5 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702914 15890363 9525338 11282024 16127465 15569154 19229295
BMPR2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 18756288 10712517 7791754
AMHR2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 16446785 14746809 11420127
BMP6 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11401330 10504300
BMP2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7811286 12700180 9872992 10712517 15064755 19229295
GDF9 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12135884
BMP15 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15621726 12044914 12419820 1204491412419820
ACVR2A GDF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
GDF9 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12135884
GDF2 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22622516 19996292
GDF5 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8702914
GDF7 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
BMP2 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17483092 10880444 21702718 17295905 25938661 20959140
BMP6 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10504300
BMP4 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8702914 23331499 21071413 16446785 12045205 8006002 7673243 7644468
BMP4 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 8702914 26330344 20860622 21054789 11241215 8006002 16189514 7644468
IL11 IL11RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23331499 12740032 10948192 7670098 8940087 10504396 26551460 16189514
BMP2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 20385559 16446785 28977600 15064755 18988627 17295905
BMP2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 17145710 17483092 10880444 10712517 26330344 21054789 16672363 10881198 11263668 20860622 15064755 18937504 25938661 15621726 12700180 10692589 19804412
BMP2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10880440 23331499 11263668 23180781 18342887 16446785 10880444 10712517 7791754 17295905 25938661 24337809
GDF1 ACVR2B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
GDF5 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 8702914 16446785
GDF2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15851468 27252362 26047946
GDF11 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12414726 23331499 1241472616845370 16845371 16446785
BMP6 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 21071413 16446785 10504300
ACVR2B ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 23180781 8622651 16446785 12364468 18988627
GDF9 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12135884 10712517
BMP5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11580864 16189514
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
BMP6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11401330 12297674 10504300
GDF6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9525338 160490149525338 16049014
GDF7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
GDF5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21543859 9525338 11282024 16127465 19229295
GDF11 ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12414726
GDF5 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8702914 23331499 9525338 23180781 18342887 16446785 19229295 87029149525338
IFNL2 IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL1 IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL3 IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IL17A IL17RC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16397230 16785495 8777726 11574464
IL17A IL17RC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17911633 19838198 18684971
IL17A IL17RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11058597 17911633 93675399367539 19838198 18684971 9367539
CCL11 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9660793 96607939660793 22633458
CCL11 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 15207250 9276730 9115216 9195948 11264152 22633458 12554737 12149192
CCL11 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 10488147 10699158 22633458 12218106 23597562 25450766 12149192 16102831 8642344 9169459 9005985 16339911 8676064 9276730 9207005 24702154 9712872 10733106 10706854 12761559 8609214 10854442
TNFSF11 TNFRSF11A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9367155 11581298 9520411 23333834 11239407 15110169 20483727 12897775 14741739
EDA EDA2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11039935 10484778 12270937 12084975
GH2 GHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 2387255 1955498
GH1 GHR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 2825030 8943276 17500058 1549776 9353194 26713839 1935820 31279174 9030599 23331499 7862673 7691587 19927328 10551877 21889455 9571026 3349036 2387255 31100495 29145629 24280222 24243840
EDA EDAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 11039935 18304980 10484778 11309369 11035039 12084975
EPO EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 8662939 9442088 15358619 9030560 9974393 9774108 18586265 23331499 2163696 10318834 21889455 17327410 16982323 29997244 9808045
IL1RN IL1R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20959797 24332029 1834644 7878046 1833184
IL12A IL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 10779781 10899108 8943050 7527811
IL12B IL23R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12023369 17587057
IL23A IL23R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 1202336912023360 12023369
IL22 IL22RA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 12941475 10875937 29608910 15120653 5898511035029 20462497 18675809 12513909 18599299 11035029
IL17RC IL17F â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16397230 16785495 8777726 11574464
IL17RA IL17F â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16397230 16785495 8777726 11574464
IL17F IL17RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18684971 19838198
IL17F IL17RC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19838198 18684971 17911633 28827714
IL17RC IL17RA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16397230 16785495 8777726 11574464
IL20RB IL19 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11196675 14580208 12351624 22802649
IL24 IL20RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17208301 23331499 12974481 11706020
IL19 IL20RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17208301 23331499 12974481 22802649 14580208
GH1 PRLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29145629 23331499 24243840 20053995 9556914 27003442 23192981 15082796 7984244 31100495 16546209
CCL15 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10699158 9346309
CCL8 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10699158 22633458 9115216
CCL23 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9886417 9558365 12381680 10699158 10660125 22633458
CCL3L1 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11170631 11449371 12381680 9115216 9624164 7545673 10202040 10660125 22633458 8530354
CCL14 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9687537 9548457 15905581 12381680 20483925 9346309 9405404 24218476 22633458 11085751
CCL8 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10699158 9005985
CCL28 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 22633458 12964882
CXCL11 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458 15178708
CCL3L1 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11449371 7594543 22633458
CCL15 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10699158 9346309
CCL13 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9276730 10733106 9005985 10699158 16339911 22633458 12149192
CCL14 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9548457 9346309 11085751
CCL24 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16102831 10488147 15207250 22633458 10733106 10699158 16339911 12218106
CCL18 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10640766 29637711 23999500 24218476 22633458 23951310
BMP15 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15621726 23331499 12419820 16446785
GDF2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28646109 15851468
BMP6 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 11401330 10504300
GDF7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
GDF6 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 9525338 16446785 18988627 160490149525338 16049014
GDF9 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1213588412135880 12135884
CCL20 CCR6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 10498628 9223454 10488147 9169459 9294137 10699158 12081481 24218476 22633458 12964882
CCL20 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9660793
CLCF1 CNTFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11294841 11285233 10966616
CCL13 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CXCL13 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11554781 16189514 22633458
CXCL11 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 15273303 9625760 15761110 12750173 10699158 16189514 11259614 12884299
AMH AMHR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8889695 23331499 8119126 16446785 18988627 79972308889695 7997230
CCL8 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115216 10699158 9195948 22633458 12554737 12149192
CCL24 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15207250
CCL13 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9276730 10699158 24890717 9195948 22633458 12554737 12149192
CCL27 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10781587 11821900 12718728 10725697 22633458
CCL28 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 10781587 22633458
CXCL13 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10706668
CCL25 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10706668
GDF1 ACVR1B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
CX3CL1 CX3CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9390561 10488147 14607932 10699158 28389721 11432858 16189514 22633458 9931005
CXCL13 CXCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 22913878 9486651 9463416 10699158 28389721 22633458
TNFSF10 TNFRSF10D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9242610 20103630 11239407 9382840 9430226
IL17B IL17RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10749887 24011563 11058597 1074988710749880
IL25 IL17RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24011563 11058597 19838198 1105859711058590
CCL17 CCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12832759 10699158 9521068 10910894
CCL8 ACKR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 26740381 9405404 10734104
GDF1 ACVR1C â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
CCL13 ACKR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 26740381 16189514 9405404 10734104
CCL25 ACKR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10706668 23341447 22633458
IL24 IL22RA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17208301 23331499 12974481
DEFB4A CCR6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20068036 26198319 25122636 25585877 10521347 11714836
CCL1 CCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 12967681 16221874 9207005 12645948 9211859 11470772 10699158 11154210 9469461 10419462 10910894
CCL25 CCR9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10498628 10699158 11159507 22633458 10229797
CCL18 CCR8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24218476 23999500