Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TYK2 IFNL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
IFNLR1 IFNL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
JAK1 IFNL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
IL10RB IFNL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15166220 19457860
IFNLR1 IL10RB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
IL10RB JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 12974481
TYK2 IFNL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
IL10RB IFNL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
JAK1 IFNL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
IFNLR1 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15120645
IL10RB IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12483210 23331499 12974481
TYK2 IFNLR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
IL10RB IFNLR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12469119 21716315 23291588
IL10RB TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 10347215 12974481
IFNL1 IFNLR1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IFNLR1 JAK1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IFNL1 IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL1 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL2 IFNLR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNL2 IL10RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17208301 23331499 12469119 12974481
IFNLR1 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15120645 23331499 27133025
JAK1 IL10RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
TYK2 IL10RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
TYK2 IL10RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 IL10RB â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
TYK2 IL10RB â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 15833879 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
JAK1 TYK2 â—¼   PHYSICAL_INTERACTION 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK1 TYK2 â—¼   SHARES_COMPLEX 85.0 1.0 ACSN 10433356 10485906 10542212 10623821 11160275 11207245 11306493 11371360 11698286 11867689 11870632 11875494 11964292 12223527 12401408 12496409 12754507 12811837 12818165 1439146 14607900 14610620 14657224 14764699 15099563 15282297 15356132 15573129 15579430 15864272 16200688 16243976 16413922 16424049 16713974 17404308 17485448 17513775 18209571 18250477 1825141 18451175 18555777 18555778 19581928 19833085 20138012 20184663 20406969 20510870 20856220 21097505 21115385 21191065 21220452 21469115 21840487 21930765 21930769 22595692 23034983 23124025 23390297 23567181 24011634 24030977 24091328 24346288 24418198 25002027 25582338 26201938 26268945 26755705 27216177 27557510 2965306 7512720 7521688 7543512 7590867 8837607 9535722 9834059 9845545
JAK1 TYK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702790 19901323 7504784 7589562 15659558 30029643