Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 CAST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 ARHGEF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 ACAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRKCA ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713049
AGTR1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
IRS1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18762365
BCL2L1 BAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BCL2L1 BAK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CAPN2 BAX â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 21887410 23242420
CAPN2 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12000759
CAPN1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12000759
NFKB1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704864 11313951
BCL2 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 10622714
CAPN2 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12000759
CDKN2A BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19049976
CAPN1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8695851
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
AKT3 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 AKT1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 AKT2 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 17544405 5219985
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP9 CASP7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
FYN CBL â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5220480 7642581
CBL ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CD44 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12748184 16189514
CLTC CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAPK3 ARRB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
MAPK3 CASP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219611 17290218
MAPK3 IRS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
CAV1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17502619 0611416104
BCAR1 ACTB â—¼   COLOCALIZATION 2.0 0.8 intact 6174726 18164686
ARPC2 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
CTTN ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
PRKCA ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15590896 10592173
ACTB CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11018051 7680654
ACTB ARPC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10592173 9600938
GAPDH EXOC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRKL ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ACTG1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ARAP1 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
GNGT1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17419683 16537363
FYN CYCS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VPS37C STAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14624836 15218037
ABI1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
CRK CAST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK ARHGEF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK AGPAT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CTTN ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12176742
ASAP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABI1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ARHGEF11 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ASAP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CAST FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
FYN GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARFGEF2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8945478 8945477
KIT PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7539802 7520444
CBLC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
KIT PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7520444
CTNNB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16132617 12200448
BIRC2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17145710 12887920
CASP8 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CAPZA1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12351658
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
CNKSR1 RHOA â—¼   PROXIMITY 2.0 0.8 intact 15670823 5217486
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
CBLB ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLB ASAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17255943 5219572
CBLC ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
CBLC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
IRS1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003536
CTNNB1 IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
CYTH1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
NFKB1 TLR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19779021 12686724
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
CYFIP2 CYFIP1 â—¼   COLOCALIZATION 2.0 0.8 intact 11438699 5214235
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
ACAP1 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP1 GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17959595
GNA12 ARHGEF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799111 10026210
AGTR1 ARFGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ARFGEF2 ARFGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19332778 0901558106
PIK3CA GNAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16268778 18515384
CTNNB1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219695
GNAQ AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219925 17498700
BIN1 AMPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21779028 11231140
AHNAK2 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
ARRB1 AGTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219925 17498700
ARRB1 AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11579203 17498700
ANXA2 AHNAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CAPZB CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CASP1 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667412
AGTR1 BNIP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
AGTR1 GNA12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CNKSR1 CYTH3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CAPNS1 CAST â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7698360 19020623
CLDN16 CLDN19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22373575 8387781
CHMP4A CHMP5 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
KIT CBL â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 8950973 16780420 25737303 15315962
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
ARPC5 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24981860
CHMP1A CHMP5 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
ABI1 BAIAP2 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
BCAR1 FYN â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
ARPC1A ACTR2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
SNX9 AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AMPH AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CRK ARAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 31980649
FYN ASAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17474147 16636290
ARF1 ARF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
SNX9 AP2A2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AMPH AP2S1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RAB7A CDC42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 31871319
CBLC BRK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CAV3 CAV1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
SNX9 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CHMP5 CHMP3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ABI1 BRK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
ASAP3 ASAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CASP5 CASP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ASAP3 ASAP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ACTR3C ARPC1B â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
ARF6 CYTH3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CXCR2 GNB1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ARHGEF1 RHOA â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 10836144
ATG16L1 WIPI2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ACTB CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17502619 28734243
CXCR2 ARRB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 11170396
BIRC2 BCL10 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16775419 33961781 10753917
KIT CBLB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12177062 15315962
WIPI2 ATG5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 30340022 33961781 24954904 26186194
RHOJ CDC42 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31871319 10967094
AGTR1 CAV1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TLR2 CXCR4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18765807 20802527
CXCR4 GNA13 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11994484 23773523
AP2A1 AMPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 12057195 33961781
RAB7A ARL8B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28325809 29360040 26344197
CLDN22 CXCR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ARPC4 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
BCL10 BIRC3 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CDC42 CAPZB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
AKT1 IRS1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10497255 17640984
AGTR1 ARRB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11579203 17498700 15611106
ACTR2 CTTN â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ACTR1A CAPZA1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CHMP1A CHMP4B â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CASP9 CASP3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11242052 8900201 25241761 1067155 15941357 11230124 15507451 18723680 17437405
ARF6 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11533043 16189514 11867621
ARF1 ASAP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16223492 16332543
AP2A2 BIN1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9195986 10430869 9182529
PIK3CA IRS1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591642
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
CHMP2A CHMP5 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CHMP2B CHMP4B â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ARF6 CYTH2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ARFGAP1 ARF1 â—¼   GTPASE_REACTION ✅ + 0.85 0.85 Signor 10102276
KIT ABL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12374739 24728074
CASP8 BCL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16183855 11406564
BIRC3 BCL10 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10753917 16395405 33961781 11466612 16775419
SNX9 AP2B1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
RAB7A CAV1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
ABI1 CYFIP2 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
BIRC2 CASP8 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
CAPN1 CAPNS1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
ACTB ACTR1A â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ACTB ACTR10 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
CYCS CASP9 â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9390557
CBLC FYN â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ACTB CAPZA1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
BCAR1 ABL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 7780740 8810278
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
BIRC3 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17069460 9384571
CRK CBLB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 19380743 25814554
CASP8 BIRC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12887920 27810922 15069192 22274400
AP2A1 AP2B1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 33961781 26344197
RHOA ARHGEF11 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 7909059 20300064
BCL2 BCL2L1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AMPH AP2A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ARF1 ARFGAP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ACTR1B CAPZB â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ABL1 ATM â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
AP2B1 ARRB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BTRC NFKB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ABL1 ABI1 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 21320496
ACTB CAPZB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CLTB CLTCL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ACTN1 ACTN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22863883 22939629
BNIP3 BCL2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10381623 7954800 23504944 10625696
FYN CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 16713569
CBLB CRKL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10022120 25814554
CRKL KIT â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11071635 9092574
BECN1 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29669822 23112296 28628118 28205554
ARF1 ARF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
TLR2 CD14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18765807 10395652 16189514
AP2A2 AP2B1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12086608 16189514 33961781 34079125 26344197
CASP7 BIRC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16339151 30948266 9384571
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ACTR1A ACTR1B â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ASAP1 CTTN â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CYTH2 ARF6 â—¼   GTPASE_REACTION ✅ + 0.88 0.88 Signor 14565977
BCAR1 CRKL â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CHMP2A CHMP2B â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
ACTR3B ARPC5L â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
BIRC2 CASP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 17069460 9384571 11084335 19258326 11106668
EXOC5 ARF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14662749 16713569
ARF6 ARRB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11533043 16189514 11867621
BCAR1 CRKL â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9498705 8810278 10753828 22974441 8978305 18835194
CBLC CRK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 10571044 25814554 10362357
CRK ASAP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 19380743 26871637
AMPH AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 10748223 33961781
AP2S1 AP2B1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12086608 16189514 33961781 34079125 26344197
CASP7 BIRC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16339151 9384571 11084335 33961781 15580265 19258326
CHMP1B CHMP3 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
BIRC3 CASP9 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CAV1 CAV2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ABL1 ABI1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5219329 17101133
ATM ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9168116 17409407 10212258 20798688 11375976 9168117
CRKL ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16443220 22286129 7493940 14604282 8978305 9820532 18835194 9710592 33961781 8524328 19823681 7926767 16955467 24412932
ABL1 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15556646 11494134 16713569 9174058 20675402 9195915 14604282 10829062 14725908 8626543 12475393 19380743 19823681 16955467
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
AP2B1 AP2M1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12086608 16189514 16713569 24189400 33961781 19380743 26186194 30021884 34079125 26344197
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
CAPN1 BAX â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19931333 21887410 23242420
AKT3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14766748 15642728 17525161
BECN1 BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22498477 21971985 20889974 20010695 23504944 23564079 23168911 25891078 29955058 23822101 32097085 23954414 19959994 28128446 22241963 16179260 23316280 31410188 18641390 29079782 29849149 28682313 27304906 20711182 25984893 22622204 19180116 20622903 33977871 23541952 24034250 22082873 21543763 19347031 31696776 9765397 16713569 24879154 24141421 17446862 24472739 24599950 28431397 20577262 19050071 32820146 21358617 21139567 23479509
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
ACTB BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CAPN1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12000759
PRKCA CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11950589 8070569 17570479
CAPN1 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16998475
CAPN2 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16998475
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
BIRC2 CASP9 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16701639 32296183 16189514 25416956 25241761 27197231 16339151 11084335 9545235 15069192 19153467
CASP9 BIRC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16701639 25241761 21988832 16339151 9545235 15069192
IRS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10854852 19546233
MAPK3 BAIAP2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
ARF6 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17363898 16452216 15210957
MAPK3 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21419341
MAPK3 AMPH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15262992
CYTH1 ARF6 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652308 11050434 1511013
ASAP2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
CRK ASAP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 17474147 9819391 33961781 19380743
CRK KIT â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9092574 24728074 9233773 12878163
CHUK BCL10 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
MALT1 BCL10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21157432 31774199 23690623 25748427 17948050 20551178 17189706 21513986 22658522 22267217 14695475 22528498 27070702 31961340 11262391 24130731 27071417 33329596 19444310 27113748 25548215 11090634 30279415 19279678 25569716 18806265 33961781 29953499 19118383 27777308
BCL10 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16280327 24462114 24412244
CCR5 CCL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11449371 10477718 10488147 9334377 8663314 14637022 9207005 11116158 9289016
CYTH3 ARF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ARF1 CYTH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18451304 9707577 10652516
ASAP1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11773070 16223492
CYTH1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9756891 9653114 10212218
CHUK MALT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
AKT3 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19609947
NFKB1 IL18 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10227974 17399992 15963597
CASP1 IL18 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 1574116 9121587 8999548
CASP5 IL18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9121587 17039247
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21118812 17620599 12070169 10097102
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARHGEF11 RHOA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
CBLB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11087752 17635922 10514377
CAV2 CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12414992 16189514 31980649 9361015 18081315 33961781 24013648 10212252
CCR5 CXCR4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12429730 15660419 18632580
NFKB1 TNIP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 21988832 19695220 35140242 33961781 25609649
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
NFKB1 AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10628750 8613256
PRKCA ADCY5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8206971 7759492
GNA13 ARHGEF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11799111 10026210
GNA12 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12515866 11094164 12024019
AKT2 MYO5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17515613
AGTR1 GNAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17498700 31160049 11313903
ASAP2 ARF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10022920 10749932
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
STAM ASAP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0509166103 7102318 16636290
WIPI2 ATG16L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28561066 34505572 29634932
SNX9 ASAP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 0509166103 7102318 16636290
GNA13 ARHGEF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11313914 15951850 22661716
ANXA2 CAV3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
CASP4 CASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12843244 9491891 9039262
ABL1 CRKL â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BIRC2 CASP9 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
ACTB ACTG1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CLTA CLTCL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
BCL2L1 BECN1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CAST CAPN1 â—¼   PHYSICAL_INTERACTION ✅ - 0.91 0.91 Signor 25969760
ABI1 CYFIP1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BAX BCL2L1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
ARHGEF11 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 32203420
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
ACTR10 CAPZA2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
AKT1 ARRB2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 18191226 19122674 19262695
ACTR3B ARPC5 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
IRS1 PIK3CA â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
BCAR1 CRK â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CHMP4B CHMP5 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ARFGAP1 ARFGAP3 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ARFGAP1 ARFGAP2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
CHMP1B CHMP5 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
CAPN1 CAST â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CHMP1A CHMP2A â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CHMP1B CHMP4B â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
MALT1 BCL10 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 17948050 6177522
ARRB2 AGTR1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 11226259 11279203 15611106 28298427
CHMP4B CHMP6 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CAPN2 CAPNS1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ABI1 ABL1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
BECN1 BCL2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 19180116 7014480
BCL2 BECN1 â—¼   COLOCALIZATION ✅ 0.95 0.95 mint 8095158 21139567
ACTG1 ACTB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACTR10 CAPZA1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BRK1 CYFIP2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACTR1A CAPZB â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ACTR3B ARPC2 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CAPZA1 CAPZA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
BIN1 AMPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 9348539 9315708 33961781 31413325
ACTR3B ARPC1A â—¼   PHYSICAL_INTERACTION 959.0 0.96 STRING 36370105
ATG12 ATG16L1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
ACTR3B ARPC3 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CHUK NFKB1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ACTR2 ACTR3B â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
ACTR3B ARPC4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ABL1 ABI1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17101133 9593709 12672821 9010225 18328268 8943360 20598684 11418237
ABL1 CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 9747873 11380621 15696159 8875975 9480911 21602891 18835194 18619508 12384576 8194526 11956190 19380743 24412932 9642287 17474147 8978305 12097319 17515907 33961781 12198159 7926767
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
FYN CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17094785 8900205 15190072 9890970 25814554 8995358 12244174 10829062 12941616 9311917 12231245 16503409 9677430 8662998 119942 9535867 10092522 15208330 7642581 15556646 16713569 8621719 10629042 7782294 8626543 10799548 11239464
CRKL CBL â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9162067 9129019 16982329 9590251 8621483 25814554 10907644 10608804 15107835 7545163 9092574 9195915 12244174 18835194 9311917 8524328 16503409 24886428 10657627 14604282 9820532 8662998 9461587 9851874 11399323 9344843 11157475 10204582 9660791 15556646 8978305 11553620 8626543 9988765 33961781 11263968 15358160 11133830
CBL CRK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 9129019 9416834 22974441 8621483 25814554 9178909 15581361 18835194 8943292 12393469 8524328 8683103 8662998 10962563 9461587 19380743 16289966 11792427 8626543 9988765 33961781 9617486 8626404
ARPC4 ARPC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 23148219 11162547 22863883 33961781 24981860 22939629 26344197
ARPC3 ARPC5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23148219 26655834 22863883 33961781 24981860 26186194 22939629 26344197
BCAR1 FYN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10739664 32296183 9360983 16713569 17474147 31413325 9188452
ATG5 ATG12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11825910 12890687 12482611 17353931 20562859 23202584 31612776 22342342 33961781 28253979 33024031 32129924
AP2S1 AP2A2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 26344197
CHMP2A CHMP3 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ACTR10 ACTR1B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ARPC1A ARPC5L â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CHMP3 CHMP4B â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CAPZA2 CAPZB â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CCL5 CCR5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BRK1 CYFIP1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ACTR3B ARPC1B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CAPN2 CAST â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ARF1 CYTH2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARRB1 CLTC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
BAIAP2 CDC42 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARPC2 ARPC5 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 26655834 22863883 24981860 22939629 26344197
ARPC2 ARPC4 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 11805826 11162547 22863883 33961781 24981860 22939629 26344197
ARHGEF11 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CHMP2A CHMP4B â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
BAX BCL2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
BAK1 BCL2L1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ACTR10 CAPZB â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BAX BCL2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21778226 18981409 15899854 32064756 10620799 21199865 17289999 9194558 8358790 21671007 16642033 21458670 22262057 9388232 10716992 20865015 14980220 9111042 24141421 17097560 15231068 9463381 33961781 17525735 29749471 23479509 26004684
ARPC2 ARPC3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 11805826 23148219 22863883 33961781 24981860 9230079 26186194 22939629 26344197
CRK BCAR1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31980649 9581808 22974441 15673687 10208419 12615911 10464310 15492270 12799422 18835194 8631823 10747099 11278916 16413489 10753828 16267043 10329689 19380743 10085298 14657239 27669437 17038317 9920935 11369773 11839772
ARPC4 ARPC5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12451597 11162547 26655834 22863883 33961781 24981860 22939629 26344197
AP2A2 AMPH â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 9280305 9195986 33961781 8552632 10748223
ACTR10 ACTR1A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
ACTR3 ARPC5L â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CAPZA1 CAPZB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR3 ARPC1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATG14 BECN1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1B ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ATG16L1 ATG5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1A ARPC5 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ACTR2 ARPC1A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC4 ARPC5L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC1A ARPC4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ATG12 ATG5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ACTR3 ARPC1B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
GNB1 GNGT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATM ABL1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 BCAR1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CRKL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ATM ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 17303408 22334513 11375976 11804596 23331499 21071413 16163361 17570479 18988627 9168116 23847781 9168117 20798688 15964794 19788416 9561848 22084676 12607003 10212258 15459660 11877377 15686624 17409407
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
ABL1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12560071 20841568
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
ABL1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22553782 24974292 29066624 15657060 20841568 28177918
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 8978305 22581121 20841568 10837221 18768933 7493940 9710592 16955467 8524328 23331499 21199784 18794134 10592173 21051857 7926767 16443220 18835194 24165979 26500649 18809728 15459660 26192618 24412932 9053848 22286129 8083188 14604282 21435002 9820532 19823681
ABL1 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 18083107 17129785 19534553 16212419 8810278 15951569 20841568 7780740
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20861316 17306540 20841568
ABL1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 17145710 20598684 18328268 12591740 9593709 20841568 18083107 7590237 11418237 12672821 17389395 19534553 8943360 17101133 9010225 11163214 26428302 21320496
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
CLTCL1 AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTB AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
BCL2 BAK1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 BAK1 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
BCL2 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 9463381 14980220 11206074 17289999 26004684 11728179 20836993 19168699
BCL2L1 BAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 22705850 9463381 22516262 31467278 32814053 9020082 23680104 34098062 18178565 15901672 16189514 17446862 20836993 23055042 19060904 17289999 32296183 10085290 14596824 15292519 29997244 31515488 11175750 9027312
BAK1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15901672 11571294 16189514 16439990
BAK1 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11447222 11175253 11326099 12232790 11741880
BCL2 BAX â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
BCL2 BAX â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 11704864 16227588 17446862 17891140 20709625 21641962 22039431 23064052 23377657 23430059 23850759 7644501 8358790 8929532 9872359
NFKB1 BAX â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 12676992 15613549 21725609 23178297 23572150 7834749
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
BCL2L1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 59.0 1.0 Omnipath 22705850 18981409 21458670 28202514 11283018 17525735 29749471 21567405 9388232 18547146 19074440 16151013 21199865 18178565 26496610 16189514 15486085 26186194 17289999 9111042 12419244 25241761 14963330 12853473 9742125 9153240 19427863 21852238 14766748 21671007 15131699 9670005 8596636 24814347 9824152 9027312
CAPN1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20709625 21670566 21414921 16129881 17593948 14612448 21266584
BCL2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 22705850 18981409 9463381 21458670 17097560 17525735 8358790 10620799 26004684 29749471 9388232 21199865 17525161 22262057 21778226 15486085 17289999 9111042 12419244 9194558 15231068 10716992 8183370 14980220 9115213 21671007 16642033 23479509 10677502
BAX CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9461218 10629050 20709625 9843949 11326099 12232790
BCL2 BECN1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 27754749 8929532 9765397
BCL2 BECN1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10604474 11704864 16179260 17106237 17446862 17891140 18612260 22039431 22885520 23064052 23377657 23430059 23850759 27754749 8929532 9765397
PRKCA BCL2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10677502 10679481 10871288 11323415 16492141 20027184 9115213 9738012
NFKB1 BCL2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 11313951 11704864 21725609 23178297 23572150
NFKB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 16254192 11567031 17673602 18031796 12835724 15120608 20332461 14978135 20446017 18566231 19259124 14739605 21503108 20103608 17098279 18158998 12032828 19233129 16022909 18761399 18987666 15934930 21224428 16453001
CASP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10409669 9395403 20139069 11948397
PRKCA BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 12039060 9115213 12213578 11323415 17610064 9738012 19117992 24212628 10677502
MAPK3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115213 10669763 9735392 11323415 21785723 9738012 10677502 23272207 25826088
BCL2L1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18835031 14980220 26186194 11583631
AKT1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
BNIP3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17145710 23504944 10625696 10381623 19136941 7954800
AKT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
BCL2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16183855 11406564
BCL2 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 23504944 17643073 23168911 21971985 19273585 16713569 19050071 16179260 23316280 22205736 23115300 18641390 28128446 17446862 23954414 22241963 23541952 29955058 25891078 29849149 24034250 24599950 9765397 25984893 21358617 18570871 16799551 19180116 20889974 20622903 23564079 19959994 20711182 23479509 19347031 20010695 21543763 22622204 24472739 17438366
NFKB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10925251 17673602 12176906 11992002 14978135 15231833 14739605 10585435 20066113 16904634 9439816 18222423 10733571 15756023 15986355 12226754 15856023 16453001 11756417 18223231
AKT1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
BNIP3 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 10625696
NFKB1 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10428780 19211554 10435632 10428030 11756417
BCL2L1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16189514 25241761 9539746
BCL2L1 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 9192670
BCL2L1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 33931087 19180116 19049976 22219388 18628207 18641390 17659302 9765397 16713569 19713971 24443581 17446862 17337444
CAST CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12684003 26496610 16189514 20679491 25969760
MAPK3 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11319218 26248159 14993287 10644690
CAPNS1 CAPN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28319173 10666632 11673052 16597616 10639123 18519038 11517928
BIRC3 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9990849 12042762 9384571 17069460
BIRC2 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 9990849 12042762 9384571 17069460 11382748 11106668 16189514 11084335
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11511102 11447317 10712510
CASP3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17544405 12124386 10579725
CASP9 CYCS â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9390557 25313070 20462491 27697150
CASP7 CASP9 â—¼   CLEAVAGE ✅ 5.0 1.0 Reactome 16916640 9922454 11752425 11701129 12824163
AKT1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 11756412 11923280 16697215 20398329 18372248 15004527 15808505 20138985 20214616 15703181 17570479 28177918 18840507 15169778 11714830 10949026 16341064 11715018 18636226 10529400 9812896 17680028 19440551 10722653 20832730 18570873 17052453
AKT2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9812896 15004527
AKT3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9812896
BIRC3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 16339151 21988832 9990849 15069192 25241761 9545235 16701639
CYCS CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19788417 16977332 9390557 16713569 12147322 12773388 10329646 12792650 15210107
MAPK3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 15547943 20080742 29416675 12040186 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
BIRC2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 16339151 9990849 15069192 25241761 19153467 9545235 25416956 31515488 16189514 32296183 16701639 11084335
CASP9 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17899380 9922454 16352606 9598997 9651578
BCAR1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
KIT CBL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11994499 16780420 12444928 17904548
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CBL STAM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
BCAR1 CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
ABI1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17395426 18594017
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
PRKCA CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10358153 17570479 25814554 11024037
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
CBL KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9092574 17904548 25737303 8950973 15315962 17635922 10514377
CBL PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8641358 9119889 19380743 8621719 7629144 17635922 10514377
CTNNB1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18483247 12782598 17724465 10027409
ATG16L1 CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20639872
PRKCA DGKZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9716136 12890670
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28096473 24043311 18211802 19261619
MAPK3 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15001544 16131083 8626671 14769130 9335553 15613682 12510059 15212693 9395471 14579029
MAPK3 ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 19651622 19153083 18767875 17322306 15456867 10347142 20068231 19413330 9388255
MAPK3 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 24342355 17290218 26036637 29233910 24484936 20937773
MAPK3 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10537323 17081983 18088087 15144186 21079800 16964243 20444238
CXCL8 CXCR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555778 18633355 18980965 21328342 21847358 24406209 25922287 26201938 26548401 27557510
CXCL8 CXCR1 â—¼   PROTEIN_INTERACTION 14.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555778 18633355 18980965 21328342 21847358 24406209 25922287 26201938 26548401 27557510
CXCL8 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 8702798 8137938 9195914 10699158 1840701 12628493 10188995 15946947 22262769 8550564 9553055 1379593 8662882 8245475 10368283 9485196 8940121 15282370 11350788 9725262 10206993
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
ACTB CDC42 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
CYTH2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9417041 16189514 14565977
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL BCAR1 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL BCAR1 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
FYN CRKL â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL BCAR1 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
BCAR1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8978305 9498705 18835194 10592173 8810278 10753828 12345678 8943292 23770091
CRKL BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8978305 9498705 18835194 10592173 8810278 10753828 12345678 8943292 23770091
RHOA ACTG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
CDC42 ACTG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24914801 15507212 16439214 22608513
ACTG1 BAIAP2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
GNGT1 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25675501 8636150 9789084 10360181 12782285 19168127
BECN1 ATG14 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 ATG14 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
NFKB1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 19289499 21725609 23178297 23572150
ATG14 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 19270693 19050071 25594178 19223761 18843052 27513923 26496610 23954414 23332761 22081109 20562859 26108642 25891078 24034250 23112296 32296183 24980960 19270696 21062745 20711182 25490155
CXCL8 CXCR2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555777 18555778 18633355 18980965 21328342 21847358 23869868 24406209 25922287 26201938 27557510
CXCL8 CXCR2 â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 15079071 17533374 17784835 17916596 18555777 18555778 18633355 18980965 21328342 21847358 23869868 24406209 25922287 26201938 27557510
CXCL8 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 7592830 8702798 22904195 9195914 10699158 7559482 12628493 23597562 10188995 15946947 8626516 8550564 9553055 1379593 8662882 19190236 8245475 9126332 10216072 1891716 9485196 8940121 15282370 9464567 11350788 11511101 9725262 10206993
CRK BCAR1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
CRK BCAR1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11146654 11353765 12094222 12432077 14697347 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172 9808620
IRS1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837978 8810325 8621590
BCAR1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 9920935 11369773 11278916 15673687 8662907 9581808 8631823 8070403 10747099 12065577 10329689 16267043 10592173 10208419 17038317 18835194 20627867 16413489 10753828 8943292 9860979 11839772 14657239 12799422 19380743 15492270 10085298 12615911
CBLB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8626404 19380743 12697763 25814554
ACTR3 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC1B ARPC4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ARPC4 ARPC5 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC4 ARPC5 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
BCL10 MALT1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 MALT1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
CBLB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15208330 16503409 32296183 25814554 8083187
FYN AGAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16841086 18469807 26001218
FYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9038210 9799234 12374739
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
FYN BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17129785 9188452 9020138 10739664 31413325 16713569 11181827 9360983 17474147
NFKB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12820969 11413310 11478739 12122011 17065335 17510282 11700023 15144466 19786024 16707500 21189258 12388374 15972972 9120310 11389171 12050170 11259372
CCL5 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 16298345 10488147 28381538 10699158 22633458 9289016 12213786 8663314 11449371 10318947 12964882 25923671 9207005 23480650 11116158 10477718 14637022 9334377 9790730
ASAP2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10022920 11304556 10749932
ARFGAP1 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 1010276 10102276 19020038 16189514 9733781
CYTH2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14654833 17563369 8945478 16189514 10198630 9417041
CBLB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15315962 12177062 17635922 10514377
PRKCA KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 7539802 12040186 7693453 19568798 15567848 14585353
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
NFKB1 CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
ATG5 CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
ATG5 ATG12 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 ATG12 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
ATG12 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11825910 20562859 17145710 12890687 17353931 22342342 9759731 9852036 23202584 11265251 12207896 12482611
ATG5 ATG16L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20562859 23262492 22342342 20639872 23392225 12665549 23202584 18448665 25484072 28594407 10406794 21575909 22847423
CD14 CASP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 21737330 12752666 15814722 16115877 14739303 21737329
CASP8 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18073771 9545235 10872455 18329793 9727491 9463409
CHUK CD14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
CHUK BTRC â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
CHUK NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
AKT2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19609947 12048203 10485710
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
CHUK NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 12482991 19442713 14743216 15494311 11976329 15489227 16382138 16713569 10022904 10469655 27554194 11158290 11297557
TLR2 CD14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16455995 17889651 10426996 15241424 16880211
CASP1 IL18 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22270365 17039247 15326478 9121587 9334240
AP2A2 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A2 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTCL1 AP2B1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTCL1 AP2S1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
NFKB1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 11418664 12760745 8135780 8934574 14741709 18285351 10608823
CXCR4 RHOA â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
ARHGEF1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 12748184 32203420 9113980 9641915 10836144 11149925
ARHGEF2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9789025 22072711 32203420 9113980 9641915 10592173 9857026 20810787 16189514 24525234 11149925
ARHGEF11 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 21988832 32203420 20300064 15530360 10526156
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
WIPF3 CDC42 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11340081 11829459 10878810 12213210 11553796 10781580 11157975
CDC42 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16714282 7512369 9113980 23434736 11306516
CDC42 BAIAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17430976 20936779 11696321 24076653 11130076 12504591 16713569 24584464 19171758 11157984
AKT1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 17640984 10497255
PRKCA IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22869320 15364919 16574739 17570479 15516986 15069075
IRS1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16354680 16150444 16931767 10592173 12175651 1380456 23643389 1381348 11313948 9374521 20966354 9624169
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 HK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 29985480 31435020
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 AGAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19176382 21460185 22450747
AKT1 AKT1S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 63.0 1.0 Omnipath 18000759 17081983 17510057 12820960 21157483 11756412 11923280 16697215 19690332 19446321 20398329 17461779 18372248 19413330 15808505 20138985 23415227 20214616 12524439 20068231 14973226 19568798 18669648 17329361 15169778 12869586 17386266 19720745 17517883 11352916 10949026 11715018 19143635 17277771 18636226 19651622 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
NFKB1 IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1777483 9135552 11781710 8455627 8029023 7636248
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
BTRC NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12482991 10835356 11158290 11953428
TNIP1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21988832 25609649 14743216 19695220
BIRC2 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16339151 9384571 16189514 11084335
PRKCA ADCY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8383119 8900209 9366262 7938004 9268695
PRKCA CYTH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 10531036 24303080 24083777 17570479 18042453 20153292
PRKCA OCLN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17570479 11502742
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A1 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
AKT2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 17287208 20398329 21506126 20028971 12040186 18218901
AKT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
ARF4 ASAP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 23945166 9819391 19153612 18685082 22983554 16431365 16038802 16136078 23567335
GNA13 ARHGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14607242 9641916 9641915 16189514 12681510
AKT2 AKT1S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17329361 19651622 17081983 17386266 17517883 12524439 11352916 20068231 18372248 19413330 17277771 14973226 18669648 23682635
AKT3 AKT1S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17440074 17517883 18372248 17277771
ARPC1B ARPC5 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
AGT AGTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12006574 21464395 10193788 10993080 16189514 15930094 9797979 16597412 17346243
BIRC3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16339151 9384571
CASP1 CASP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11051551 11536016 11432859 15383541
AVP AVPR1B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2991279 4065330 8106369 7929452
AVP AVPR1A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 2991279 4065330 8106369 7929452
AVP AVPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15084136 9334232 10519430 12446593 10780976 9884074 1560825 9322919 9264324 9459574 9864265 8106369 10866830
AVP AVPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 15084136 10519430 12446593 10780976 9884074 1560825 9322919 11012895 9264324 7774575 11857925 9459574 9864265
AVP AVPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 15084136 10519430 12446593 10780976 9884074 9322919 9264324 9459574 16158071 7929452 9864265