Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ERG28 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMPD1 CASP8 â—¼   COLOCALIZATION 2.0 0.8 intact 8095238 21157428
TNFRSF1A CASP8 â—¼   COLOCALIZATION 2.0 0.8 intact 8095238 21157428
CCSER2 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WIF1 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
EEF1A1 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TSHR CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CRADD WIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
PTGER4 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
NSMAF SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12391233 20080539
RIF1 SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TNFRSF1A SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12391233 20080539
RIPK1 PIDD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17159900 16360037
CRADD RIPK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8985253 9044836
CASP2 PIDD1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CASP8 BID â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11832478 12097160 15659383 12196516 9727492 11085743 9727491
CASP8 BID â—¼   CLEAVAGE ✅ + 0.89 0.89 Signor 9727492
EEF1A1 MAP3K14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ERG28 BID â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRADD CASP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27107012 8985253 23049853 11156409 11832478 9695946 32296183 15073321 16652156 29875129 25416956 16189514 31467278
PIDD CASP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15073321 16652156 16360037 19203584 16189514 21415862
CASP2 EEF1A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRADD PIDD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23049853 15073321 16652156 16360037 19203584 17159900 20935634 16189514 27773430 21415862
CASP2 CRADD â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CASP8 RIPK1 â—¼   CLEAVAGE ✅ - 0.9 0.9 Signor 10521396
CASP8 RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CRADD PIDD1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CASP8 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11002417 10753878
RIPK1 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11116146 15047705
PIDD1 CRADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 16652156 15073321 16189514 17159900 27773430
PIDD1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16360037 17159900
PIDD1 CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15073321 16189514 19203584 16652156
BCL10 CRADD â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 11356195 16818229 17052756 17462996 18264101 21199863 22323537
CASP8 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9727492 10364179 10805722 11832478 12196516 18458084 9727491 11085742 11085743 12097160 9873064
CASP2 BID â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9727492 10364179 10805722 11832478 16189514 11085742 11085743 16495337
CRADD CASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 11156409 27107012 11832478 25416956 23049853 15073321 31515488 31467278 32296183 16189514 16652156 8985253 9695946 11399776
CASP2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19935698 20125124 15590671 10521396
CASP2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15262979 16193064
TNFRSF1A CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15357952 12887920 21741934 8875942 15725726
CASP8 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 11002422 34389694 19524512 8657102 17047155 10469655 21458669 21419663 21525013 12842894 18570872 21741934 10521396 11002417 12884866 20203691 22421964 11042193 20125124 12887920 12215447 19935698
CRADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8985253 9044836
RIPK1 MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP2K4 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
RIPK1 MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TNFRSF1A MAP2K4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TNFRSF1A MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
RIPK1 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
RIPK1 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
NSMAF SMPD1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11279185 11435466 12404124 12531547 1330325 16716889 24021978 28765050 8663014
TNFRSF1A NSMAF â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423
TNFRSF1A NSMAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12391233 10187805 17599063 8808629
RIPK1 TNFRSF1A â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
RIPK1 TNFRSF1A â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TNFRSF1A RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 25681446 11002422 20547836 8612133 18450452 27552911 26802121 10356400 19773432 18621737 23815148 16611992 22179575 12721308 21741934 7538908 18949366 21113135 8985253 10744744 10795740 21119000 22733818 10755617 27321185 15115707 24098568 18939944 18329793 20825417 20448643 15357952 21737329 12887920 24130170 15258597 24758719 16115877 19524513 18724939 16968706 22817896 28817177 18022363 19815541 25388546 21331078 22848449
TNFRSF1A SMPD1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 11112697 11274345 11279185 12531547 12646658 1330325 1431106 14607933 14625680 15099563 15310755 15699106 17916596 18633355 19411070 20038811 20184663 21133840 21411734 21826665 21920725 22955274 23170255 23430059 23510023 23567181 23769623 24092389 26201938 26801188 28765050 8663014 8910423