Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT NEBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MDC1 NEBL â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
ELK1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10913190 19687146 11520792
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
MDC1 BDH1 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368