Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
XIAP CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11242052 5213680
XIAP CASP9 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
APAF CASP3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11550094 21827945
APAF XIAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11242052 19698783
K1683 APAF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
OMD APAF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEFI8 APAF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APAF HS90A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10934467 15001356
WDFY3 APAF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEFI8 WDFY3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XIAP CASP3 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 9525868 6547707
ENDOV APAF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NALP1 CASP9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11113115 11076957
PP1A APAF â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17274640
CASP9 B2CL1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25241761 16189514 9539746
B2CL1 CYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25241761 9192670 16189514 16713569
CASP9 CASP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1067155 11242052 11230124 18723680 25241761 15941357 17437405 8900201 15507451
NALP1 B2CL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19223583 17418785
APAF B2CL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12963020 9539746 9488720
APAF NALP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11113115 17418785
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
APAF CYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16979168 10206961 12147322 16713569 9267021
APAF HSP74 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10934467 31577950 22143029
B2L10 APAF â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 9829980 9878060 10486928
HS90A HSP74 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 27187154 26344197 27708256 33571422 18408180 18620420 16314389 21360678
XIAP CASP3 â—¼   UBIQUITINATION ✅ - 0.94 0.94 Signor 11447297
PP1A B2CL1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 17274640 12115603
CASP9 APAF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9390557 21827945 9878060 27197231 19494828 16979168 9539746 9837928 19698783 10376594 27476169 11113115 15262985 28716524 9922454 10206961 11242052 20462491 20829884 9488720 21060833
CASP3 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CASP9 XIAP â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
XIAP CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 23074197 16543147 22072751 12624662 18521960 22815893 11157976 15650747 15200957 11927604 11230124 9384571 16869888 9545235 23979166 18723680 16189514 11359776 15507451 9230442 19273858 26186194 10508158 25241761 12529384 19559631 11257230 12874265 9525868 17291493 11583623 11257232 17069460 12181739 10548111 11447297 15014070 19698783
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
XIAP CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 15069192 15280366 25416956 18022362 11157976 31467278 15200957 11927604 11230124 12042762 16322207 9545235 11801603 25502805 14512414 16189514 15300255 15507451 10508158 25241761 27107012 14523016 17179183 16352606 11242052 32296183 16701639 17291493 12620238 15749826 12181739 11390657 29997244 31515488 23074197 19698783