Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
 
The Proteome Knowledge Graph

The PKG represents one of the most high resolution, comprehensive Heterogeneous network models of proteome associations.

The PKG webtool provides a range of novel search tools for identifying associations across the proteome including finding the shortest path between two proteins and finding proteins that are well connected to any initial set of proteins.

Description Comprehensive representation of human protein-protein relationships (PPR)
Quality Human PPR pairs
(PKG score > 0.7)		 3.25M
Sources of PPR data 18
Relationship types (Non-redundant) 71
Signed relationsips ✅
Directional relationsips ✅
Scoring system Normalised scoring for comparison across sources
Availability Direct access to neo4j database, API and webtool
Public Data Processing
Collation