Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EMD ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0020231 15328537
SPTAN1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IFIH1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0700544104 17600090
MYH9 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKE IFIH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0700544104 17600090
IKBKE STING1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0900850106 19433799
IKBKE CYLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
IKBKE TANK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 21212807 8142110
IRF3 IKBKE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20304918 21182093
SIKE1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16281057
MYH9 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
TBK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TXLNA IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CYLD IKBKG â—¼   DEUBIQUITINATION ✅ 2.0 0.8 Reactome 12917691 15620648
FADD IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227629 23131831
TRAF2 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
DDX58 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
RNF135 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
TRIM25 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
MAVS IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
IRF7 TRIM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
IRF7 IFIH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
IRF7 IFNA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19349300 12242290
IRF7 IFNA7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938111 19349300
IRF7 IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19164128 16824573
IRF7 IFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16410796
ISG15 IRF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20308324 16914094
IRF3 ISG15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354379
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
TRAF2 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF3 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNF CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21887257 19287455
DDX58 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRIM4 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
IFIH1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
MAP3K1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008162 10465784
RNF135 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRAF6 TNIK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
NLRX1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21703539
IRF3 IFNA7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19349300 12821121
IRF3 IFNA14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19349300 11303025
IRF3 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17035306 20483755
IRF3 TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
IRF3 TBK1 â—¼   COLOCALIZATION 2.0 0.8 intact 17599067 5220070
STING1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22394562 18818105
IRF3 CXCL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354379
IRF3 IFNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16410796
TRAF2 PIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PIN1 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16699525
IFIH1 RNF125 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0611551104 17460044
FADD MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NFKBIB NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK NFKBIA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 12799363 23430059
MAP3K1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689078 16681998
MYH9 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNIK MAP3K7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
MAP3K7 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219785 17363973
CYLD MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29291351 18332137
CYLD RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 23010170
CYLD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17981138 19131965
RIPK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18949366 24323043
RIPK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21119000 18362886
DDX58 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRAF2 RNF135 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRAF2 TRIM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRAF2 IFIH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TNIK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
TRAF2 MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 10490605
IFIH1 ATG5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0704014104 17709747
IFIH1 ATG12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0704014104 17709747
MAVS CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16406812 21419663
CASP8 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
CASP8 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11002417
NFKBIB CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK IKBKB â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12799363 23430059
RELA IKBKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12842894 5216511
TRAF3 TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8565075 5220916
MAVS CYLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
TBK1 CYLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
TNIK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
TRAF3 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16306936 16281057
STRIP1 PPP2CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SIKE1 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SIKE1 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R1A MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SIKE1 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PDCD10 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SIKE1 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MOB4 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
DDX3X TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
NLRX1 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18200010
TRAF3IP3 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SIKE1 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PDCD10 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 FGFR1OP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 PDCD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 PDCD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN PDCD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 PDCD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PDCD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SIKE1 PDCD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PDCD10 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN STK25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STK25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 STK25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 STK25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK25 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 STRN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STRIP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 STK24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 STK24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 STRN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 STRN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRIM25 IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353649
TRAF3IP3 STRIP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK26 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 SLMAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 SIKE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TRAF3IP3 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRIP1 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TKFC IFIH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0700544104 17600090
IFIH1 TKFC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0700544104 17600090
IFIH1 DHX58 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606699104 17190814
TKFC IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17600090
TRAF3IP3 STK26 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
MAPK8 MAPK9 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
IKBKG MAVS â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CASP8 TRAF6 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
IFNA4 ISG15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNW1 ISG15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ISG15 IRF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308324 32726803
TRAF6 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 27507811
DDX58 IRF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18636086 16153868
IRF3 PP2AA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27956528 32878885
KIF2B TXLNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 STRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 STRN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 SLMAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 STRN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NHSL2 FGOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NTAQ1 TRAF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAVS ATG12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22749352 17709747
MAVS CYLD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18636086 30410068
CYLD DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27591049 31762063
OTUD5 TRAF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24763515 17991829
DHX58 DDX58 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17190814 31237466
EXOC1 SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EXOC1 STRN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRS8 STRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A STRN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A STRN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A STRN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FGOP2 STRN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
TNR1A SLMAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SLMAP FA40B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 33961781
TRIMM SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRS8 SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ZC21C SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 33961781
KIF2B SIKE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SIKE1 2AAB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18782753 26496610
IFNA4 IFNA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRS8 FA40A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRS8 FGOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRS8 PHOCN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A PHOCN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PHOCN PDC10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 18782753
TNR1A FGOP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TNR1A FA40A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PP2AA FA40B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26496610 25531779
FGOP2 FA40B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
IFNA4 IFNA8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNA4 IFNA7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IFNA8 ISG15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IFNA5 ISG15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
IFNA2 ISG15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MYH9 ACTB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22366308 16186248 26496610
IFNA5 IFNA6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RIPK1 CYLD â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17981138 21408173 33654169 22848449 28900035
TRADD TRAF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8565075 30561431
T3JAM MST4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 18782753
PP2AB SLMAP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19156129 26496610 33961781 26186194
PP2AB SIKE1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19156129 26496610 33961781 26186194
IFNA2 IFNA5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PP2AB FGOP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 26496610
PP2AB FA40B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26496610 25531779 33961781 26186194
PHOCN T3JAM â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 18782753
PHOCN FGOP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18782753 26496610 19156129
T3JAM 2AAB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 18782753
IFNA5 IFNA4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CHUK NFKBIB â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CYLD TRAF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
AZI2 IKBKE â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MAP3K7 RIPK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NFKBIA IKBKG â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
IKBKG NFKBIA â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 8209688 16126728 506093200
TNF RIPK1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 23815148 8432069
TRAF2 TRAF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9718306 30561431 15383523 21903422
2AAB STRN3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26496610 17540176 33961781 24366813 18782753
2AAA FA40B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 28330616
CYLD RIPK1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX58 RNF135 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
IKBKB NFKB1 â—¼   PHOSPHORYLATION ✅ - 0.84 0.84 Signor 11158290
TRAF6 IRF7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18710948 30927622 21743479 21183682 15361868 22095711 26224488
TRAF6 CASP8 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27810922 16436380 30979779 16920630
CYLD TRAF2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27591049 12917691 23405219 28900035
MST4 FGOP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 23455922 18782753 26496610
PP2AA FGOP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28330616 26496610 19156129
2AAA FGOP2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 28330616 26496610 19156129
PPP2CB STRIP2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
PPP2CB SLMAP â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CHUK RELA â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 10521409
EMD ACTB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16189514 17620012 12670476 15328537
MYO1E MYH9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26344197 26496610
TBKBP1 TBK1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220020 17568778
NLRX1 MAVS â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18200010 28542569
PP2AA PP2AB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 27880917 26344197
T3JAM 2AAA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33961781 18782753
FA40A FA40B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 33961781 18782753
TANK TNF â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
IKBKE TNF â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
IRF3 MAVS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16153868 22908223 25636800 24379373 21903422
ATG5 MAVS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22749352 17709747
CASP8 TRADD â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19524513 18776134 17047155 12887920 29108854 30561431
STX11 TBK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 21988832
MAVS DDX3X â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20127681 27980081
STRN FA40B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24366813 33961781 18782753 26496610
T3JAM STRN3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
STRN3 FA40B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24366813 33961781 18782753 26496610
PDC10 STRN4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
T3JAM STRN4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
PDC10 SLMAP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24366813 33961781 18782753
FA40A SIKE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
PHOCN SIKE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610 19156129
PDC10 SIKE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
STX11 SIKE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 32296183 33961781
SIKE1 FA40B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
SIKE1 FGOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
PP2AB PHOCN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19156129 26496610 33961781 26186194 18782753
PHOCN FA40A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33633399 33961781 18782753 19156129
PHOCN FA40B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 19156129
T3JAM PP2AA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
PDC10 2AAA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18782753 28330616
T3JAM FA40B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
T3JAM PDC10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
T3JAM FGOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
PDC10 FGOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753 26496610
FA40A PDC10 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18782753
FA40A FGOP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 18782753 26496610
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CASP8 TRAF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FGFR1OP2 PPP2CA â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TANK TRAF3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
IKBKE MAVS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CHUK MAP3K7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IFIH1 MAVS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAVS TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAP3K7 TRAF2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IFNA14 ISG15 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
IKBKE IRF3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IFNA2 ISG15 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
IFNA14 IFNA6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
NFKBIA NFKBIB â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IRF3 MAVS â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IKBKB TRAF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CHUK RELA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
NFKB1 NFKBIB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IKBKE TRAF3 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
IRF7 IRF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18641315 11162841
TRAF2 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 16189514 16260598 21782231 16713569 25416956 9500555 33961781 21516116 21903422
TBK1 TXLNA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 29395067 33961781 32707033 21903422
TXLNA TXLNB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 25416956 33961781 21903422
RIPK1 TRAF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8612133 32296183
CASP8 TRAF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23142077 22179575 17047155 28972304 12887920 16227629 21282461 11340079 30054040
TNIK TRAF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22904686 10521462
CASP8 TRADD â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
TBK1 CYLD â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18636086 25923723 29755980
T3JAM TRAF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32366851 31390091 14572659
TBK1 MAVS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23028469 16153868 32366851 28346439 21813773 29125880 32511263 24643253 25636800 33372174 21903422 29743353
MAVS IFIH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22623778 16127453 19881509 19416887 32612200 22301138 17600090 33372174 33649232 30193849 27312109 21903422
STK25 MST4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 26186194 32707033 23455922 18782753
STK24 MST4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23455922 18782753
FA40A MST4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 18782753
MST4 PP2AA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 18782753
MST4 SIKE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23455922 18782753
MST4 FA40B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23455922 18782753 33961781
PHOCN STK25 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23455922 18782753
STK25 FA40A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 26186194 32707033 18782753
STK24 FA40A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 17353931 18782753 25531779
PP2AA SLMAP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28330616 18782753 26496610 19156129
2AAA SLMAP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28330616 33961781 18782753 19156129
SIKE1 PP2AA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28330616 18782753 26496610 19156129
IKBKG TANK â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CHUK TRAF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CASP10 CASP8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CYLD IKBKG â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IRF7 TRAF6 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IKBKB RELA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
IKBKG TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MAVS TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TBK1 TBKBP1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
IKBKE TANK â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAP3K1 MAPK8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
TRAF6 PRS8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 14743216 33961781 28514442
RIPK1 FADD â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11854271 23972990 24098568 33469115 11002422 26733177 19524513 26865630 32296183 22864571 27560715 23744296 32024820 21183682 30561431 21052097 19373245 24577083 21458669 21737329 32707033 21525013 22848449 29497034 33961781 26186194 26972597 21620750
TRADD RIPK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8612133 24735611 27768232 21724995 16603398 30561431 23429285
MAVS TRAF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 27348524 16153868 31806368 30527812 29125880 33582548 32877691 26221961 21516116 31390091 30561431 21903422
TRAF3 TBK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22330071 32324863 29125880 27135603 22792062 23986588 20174559 22079989 22908223 33608556 28049150 32779804 24763515 33372174 24622840 23717208 19380580 23308279 34084167 17991829 29920243 33187908 26928339 33411856 31404116
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
MAVS DDX58 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22114345 20007272 32612200 31433974 20071582 22022264 19164550 30193849 30267576 21903422 33649232 20554965 16153868 20080758 21102435 21292167 29053956 26494172 26061460 33372174 28594325 21844353 30558248 16127453 18200010 16177806 22301138 17190814 29263274 24478431 20434986 22623778 16585524 19193793 34544279 17709747 19454348 20406818 33976430
PHOCN MST4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753 19156129
MST4 STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
MST4 2AAA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753 28330616
SIKE1 STRN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
T3JAM STRN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 18782753
PP2AB STRN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19156129 26496610 33961781 26186194 18782753
STRN FGOP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
STRN PP2AA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18782753 19156129 26496610 33961781 10681496 28330616
STK25 SIKE1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 2AAA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 2AAB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 STRN3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 32707033 23455922 18782753
STK25 STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 FA40B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 PP2AA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK25 FGOP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
PDC10 STRN3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 33961781 24366813 18782753
PP2AB STRN3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19156129 26496610 33961781 26186194 18782753
STRN3 SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
STRN3 FGOP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
SIKE1 STK24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753 26496610
STK24 PHOCN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 17353931 23455922 18782753
STK24 PP2AB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 17353931 23455922 26496610
STK24 2AAB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753
STK24 PP2AA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753 26496610
STK24 FGOP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753 26496610
STK24 FA40B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 23455922 18782753 25531779
PP2AB STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19156129 26496610 33961781 26186194 18782753
FA40A STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 18782753
SIKE1 STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 18782753 26496610
PP2AA STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28330616 18782753 26496610 19156129
SLMAP STRN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24366813 24255178 26344197
STRN4 PHOCN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18782753 26344197 19156129
PHOCN SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24255178 24366813 18782753 19156129
SIKE1 SLMAP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26496610 33961781 24255178 24366813 18782753
T3JAM SIKE1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 18782753
SIKE1 2AAA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18782753 23443559 19156129 26496610 33961781 28330616
PP2AB FA40A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19156129 26496610 25531779 33961781 26186194 18782753
PP2AA PHOCN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18782753 19156129 26496610 33633399 28330616
FA40A PP2AA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18782753 19156129 26496610 25531779 33961781 33633399 28330616
T3JAM FA40A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 18782753
TXLNA TXLNB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
TANK TRAF2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
NFKBIB RELA â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
TNF TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
IKBKB MAP3K7 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
IKBKE TRIM4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
IKBKE RNF135 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
IKBKE TRIM25 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
PPP2CA IKBKG â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 506986200 8205130 16129692
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
IRF3 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20483755 15367631 15664995
MAVS IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950 16153868
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDX58 TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
TRIM25 TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
MAVS TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
RNF135 TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
TANK IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
TANK TRIM4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
TANK SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
TANK TRAF3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22079989 14743216 26779844 19380580 14517219 34084167 12005438 33961781 8710854 17823124 30561431 21903422
SIKE1 TRAF6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
TRAF6 MAVS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27348524 16153868 20080758 31806368 22908223 30527812 29125880 23545497 32511263 26385923 26221961 31390091 21903422
TRIM25 IRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12692549 16153868 16846591
PIN1 IRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19125153 16715065 16699525
IRF3 RNF135 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12692549 16153868 16846591
IRF3 IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12692549 16153868 16846591
IRF3 TRIM4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12692549 16153868 16846591
IRF3 TBK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23028469 31534043 25636800 16394098 30267576 21903422 22079989 15695821 32241891 20628368 18636086 15841462 19380580 28346439 18583960 25803835 17599067 12692549 19153231 22388039 24807708 19656901 22072751
IRF3 TBK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843640 20304918 18636086
IRF3 IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16219795 19164128 16824573
DDX58 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28346439 26811330 16153868
PIN1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16699525 19265157
RELA PIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19458071 19668231 16950761
PPP2CA MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
CASP8 RIPK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27810922 23972990 24098568 33052227 14681455 19773432 33469115 18485876 22274400 26733177 19524513 22864571 29431638 25939870 19524512 11002417 18570872 29021293 27552911 29274253 22179575 22173242 19373245 25911380 22585859 21737330 24577083 21458669 21282461 21737329 20825417 19060883 32707033 21525013 23429285 10521396 17047155 12887920 23955153 26972597 12215447 12884866
RIPK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 24735611 23972990 16603398 8612133 32296183 16291755 11181075 19815541 24434549 30561431 21810480 11479302 31502302 27768232 20577214 25716317 21282461 25882049 8702708 9020361 16713569 29352166 23007157
TRAF2 SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
TRAF2 TRADD â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 9020361 32296183 16713569 11479302 11181075 19815541 10892748 12796506 27768232 23955153 8702708 32968279 8565075 30561431 23429285 10911999
PPP2CA TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
PPP2CB TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
TRAF2 TNIK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10521462 22904686
PPP2CA CHUK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8209688 506093200 16126728
TBK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10783893 21138416
TRADD TNR1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22297296 11684708 21724995 8943045 9082980 24130170 32968279 8565075 30420664 7758105 16919273 19524513 8612133 24758719 9129204 29108854 8621670 10187805 27552911 18776134 19781631 9916731 11821416 9915703 15310755 23429285 16611992 11035039 18939944 19641494 11934887 23955153 33961781
DDX58 TRAF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 TRIM4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 TRIM25 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 RNF135 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
IFIH1 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950 16306936 16858409
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
STRN PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29802198 10681496 18782753
DDX58 SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
TRIM25 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
RNF135 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
TRIM4 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
IFIH1 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
TBK1 AZI2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21931555 14743216 17568778 29395067 14560022 30420664 27620379 29251827 32707033 21903422 23286385
MAVS SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
DHX58 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950
PDC10 MST4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 25416956 23665169 33961781 23541896 32707033 23455922 18782753 26344197
MST4 STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 32707033 23455922 18782753 24366813
MST4 STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 32707033 23455922 18782753 24366813
MST4 SLMAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 24366813 23455922 18782753
FA40A STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753
PHOCN STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19156129 26496610 33961781 24255178 24366813 18782753 26344197
PDC10 STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 26496610 33961781 24366813 18782753
STK25 STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26186194 32707033 23455922 18782753
STK24 STRN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 26496610 33961781 24255178 32707033 23455922 18782753
STRN STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 22939629 18782753
STRN SLMAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753 26344197
STRN STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 24366813 18782753
STK24 STK25 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17353931 33961781 26186194 32707033 23455922 18782753
STK25 PDC10 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 25416956 23665169 33961781 17657516 21516116 26186194 32707033 23455922 18782753 26344197
PHOCN STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19156129 26496610 33961781 24255178 33633399 24366813 18782753 26344197
PP2AA STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18782753 19156129 26496610 33961781 10681496 33633399 28330616
FA40A STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 33961781 24255178 33633399 24366813 18782753
STK24 STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 17353931 26496610 33961781 24255178 24366813 23455922 18782753
2AAA STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 23443559 19156129 28330616 17540176 26496610 33961781 33633399 22939629 18782753
SIKE1 STRN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 26496610 33961781 24255178 24366813 18782753
STRN3 STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 22863883 33961781 24255178 24366813 18782753
PDC10 STK24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 25416956 17353931 22863883 33961781 17657516 21516116 23541896 32707033 23455922 18782753 26344197
STK24 STRN4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 17353931 23455922 18782753
STK24 SLMAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 32707033 23455922 18782753 24366813
STK24 2AAA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 17353931 23455922 18782753
TRIM25 SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
FA40A SLMAP â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 33961781 24255178 24366813 18782753 26344197
RNF135 SIKE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
SIKE1 IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
SIKE1 TRIM4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10581243 12133833 19479062
DHX58 IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950
IL12B IL12A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10899108 10779781 7527811
2AAA PHOCN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18782753 23443559 19156129 26496610 33961781 33633399 28330616
FA40A 2AAA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18782753 19156129 26496610 33961781 33633399 28330616
CASP8 RIPK1 â—¼   CLEAVAGE ✅ - 0.9 0.9 Signor 10521396
TRAF6 MAP3K7 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18758450
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
PDCD10 PPP2R1B â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PPP2R1A TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PDCD10 PPP2CA â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
STK25 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
STK24 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
STRIP1 STRIP2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
FGFR1OP2 SLMAP â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
IRF3 TBK1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
TBK1 TANK â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5220020 17568778
TBK1 IRF3 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17599067 5220070
TBK1 IRF3 â—¼   PHOSPHORYLATION ✅ 0.92 0.92 mint 6948053 18583960
TBK1 IRF3 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 17599067 5220070
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
MST4 STRIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CASP8 RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
DDX58 TRIM25 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MOB4 PPP2R1B â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MOB4 PDCD10 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PPP2R1B STRN4 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
STK24 PDCD10 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 8153045 21516116
2AAB STRN â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 26496610 17540176 33961781 24366813 18782753
SLMAP FGOP2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 24366813 33961781 24255178 26496610
PPP2R1B STRIP1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
TBK1 TRAF3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
TRAF3 MAVS â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 27348524 27980081 32366851 32324863 29125880 22792062 22022264 30267576 22079989 31806368 20080758 21200404 22908223 30527812 33608556 31390091 26221961 24622840 16858409 33582548 19419966 22901541 32511263 19893624 26519536 23545497 33411856
IL12A IL12B â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
TRADD FADD â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24686082 32296183 12107169 12796506 8681376 21724995 12911633 23955153 11112409 16919273 8565075 30561431 10911999
FADD TNR1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16611992 15659383 11035039 9129204 8565075
RIPK1 TNR1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 24098568 16115877 18949366 19773432 24130170 30420664 21113135 11002422 19524513 8612133 18450452 24758719 29431638 25388546 19815541 28388439 27591049 22817896 28817177 22733818 27552911 18022363 16968706 22179575 19781631 27321185 31406107 15258597 18621737 21737329 20825417 25681446 23429285 16611992 20448643 21331078 18724939 22848449 18939944 7538908 26802121 8985253 33961781
TBK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 14743216 32707033 20449947 20562859 29125880 23007157 27135603 30420664 33961781 10990461 30561431 21903422 32041822
TRAF2 TNR1A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 25241761 24735611 8943045 32968279 8565075 30420664 8612133 28388439 19815541 29108854 30561431 18776134 22179575 18022363 27321185 31406107 11821416 26212014 16611992 20448643 16713569 20333651 15743837
2AAA STRN4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18782753 23443559 19156129 26496610 33961781 28330616
2AAA 2AAB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 23443559 26496610 17540176 33961781 18782753 26344197
PPP2CB PPP2R1B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
IKBKB NFKB1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
TANK TBK1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CHUK NFKB1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
TBK1 TANK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21931555 16189514 31114588 21988832 30420664 21903422 14743216 10581243 29395067 30561431 23286385 27035970 25409927 17823124 32707033 17568778 24488098 23007157 33961781 18307994 29251827
TANK TRAF2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 14743216 16189514 16713569 21988832 20562859 10581243 23007157 12005438 33961781 8710854 10759890 28155233 30561431 21903422
NFKBIA IKBKB â—¼   PHOSPHORYLATION ✅ 0.97 0.97 mint 8209688 16126728 506093200
ATG5 ATG12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11825910 12890687 12482611 17353931 20562859 23202584 31612776 22342342 33961781 28253979 33024031 32129924
2AAA STRN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 23443559 19156129 28330616 17540176 26496610 33961781 24255178 18782753
2AAB PP2AB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19156129 26496610 33961781 26186194 12370081 26344197
PP2AB 2AAA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 15936019 23443559 27880917 19156129 28330616 26496610 33961781 27173435 26186194 24981860 12370081 18782753 26344197
2AAB PP2AA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19156129 28330616 18715871 17540176 26496610 22939629 12370081 8392071 18782753 26344197
IKBKG IKBKB â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219009 16938294
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CASP8 FADD â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 5219431 17159907
AZI2 TBK1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
TRADD TRAF2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DDX58 MAVS â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NFKB1 NFKBIA â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
FADD CASP8 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 21785459 23142077 21988832 23972990 17290218 24098568 14681455 20103630 33469115 18485876 22274400 22864571 25043603 27560715 25939870 29795330 19524512 17159907 30561431 27552911 19176810 15659383 9343261 22179575 22173242 25911380 27321185 8681376 15280356 21737330 26437781 31046799 21458669 12702723 11717445 21737329 19060883 21525013 23429285 20448643 12107169 17047155 9228018 12887920 29497034 12911633 14612908 23955153 33961781 20829884 26972597 21620750
2AAA PP2AA â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 15761952 10191253 25438055 19156129 22167190 18715871 19915589 17540176 8617797 33856059 12370081 21460856 26496610 24841198 18782753 28330616 27880917 22379092 17274953 17632056 22939629 21159657 19818709 18394995 17374643 17529992 23443559 17055435 19293187 22863883 33961781 33633399 26344197
CASP10 FADD â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1B SIKE1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1B TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 PPP2R1A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A SIKE1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A SLMAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2CA SIKE1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2CA SLMAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2CA TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 SLMAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FGFR1OP2 STK24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FGFR1OP2 MST4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FGFR1OP2 PDCD10 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FGFR1OP2 STK25 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
FGFR1OP2 SIKE1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 STRIP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 SLMAP â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 SIKE1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDCD10 STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MST4 SIKE1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MST4 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MST4 STK24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MST4 STK25 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SIKE1 STK25 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STK24 STK25 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN3 STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SIKE1 STK24 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN4 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SIKE1 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRIP1 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MOB4 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1B STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1B STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MST4 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 PPP2R1A â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MOB4 SIKE1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
FGFR1OP2 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MST4 STRIP2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MST4 SLMAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SIKE1 STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STK25 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STK25 STRIP2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STK25 STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STRN3 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SLMAP STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STK24 STRIP2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STK24 STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SIKE1 STRN4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SIKE1 STRIP2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STRIP2 TRAF3IP3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SIKE1 STRIP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2R1A STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MST4 PPP2CA â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2CA STK25 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2CA STK24 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FGFR1OP2 MOB4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRIP2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MOB4 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
FGFR1OP2 STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MST4 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MST4 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MST4 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK25 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK24 STRN â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK25 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK25 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK24 STRN3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
STK24 STRN4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SLMAP STRIP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
IKBKG NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
MAP3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FADD RIPK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CHUK NFKBIA â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ATG12 ATG5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1B STRN3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1B STRN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1A STRN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1A STRN3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FGFR1OP2 STRN3 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
FGFR1OP2 STRN â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
STRIP1 STRN4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SIKE1 SLMAP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
IKBKB NFKBIA â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP1 STRN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP2 STRN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP2 STRN3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP1 STRN3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKBIA RELA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MOB4 MST4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PDCD10 STK24 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SIKE1 STRN3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TRAF3 IKBKE â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12692549 15210742 16306936 16281057 14530355 17526488 17047224 14703513 23453971
IFIH1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16177806 17020950 15210742 15210743 16306936 16127453 12702806 16858409
MAVS IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 15210743 16127453 19153231 17020950 25636800 15210742 16306936 12702806 16177806 27419230 36056146 19546225 19380491 16858409 21200404 24706939 18207245 17468758 17327220
DDX58 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16177806 17020950 15210742 15210743 23950712 16306936 16127453 17468758 12702806 17327220 16858409 16281057
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
TRAF3 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 16858409 24763515
IKBKE IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 16127453 19153231 12692549 24722368 15210742 20532218 12702806 16380379 14703513 29800227 14679297 17706453 24396068 18440553 16281057 16625202 9463386 18818105 16199137 9566918 15695821 14739303 21138416 17526488 15212693 16914100
IKBKE IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 25225665 9786932 15210742 22787218 10893229 26712804 16127453 12702806 16380379 15367631 12692549 17706453 16199137 16914100
IKBKE CYLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19287453 18636086 27844253 20863366 19481526 29755980
IKBKE TANK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17823124 21212807 21138416 21931555 12133833 17568778 25852190 23007157 10759890
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
IKBKE RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 28317833 12842894 16046471 20188669 15128824 17561400 17003035 30223576 15485852 10521409 15489227 15849198 16407239 26025205 15212693 12767944
IKBKE NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10783893 18794072 8657102 8601309 15939554 12138192 10329681 10882136 9721103 12403772 21171089 16888014 15879144 20717897 16007147 7796813 11815618 10421793 25133483 21872579 10398585 16199137
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKBIB IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKBIA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
TRAF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
NFKB1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
MAP3K7 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TRADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
MAP3K1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9008162 19666475 9689078 12221085
IKBKG NFKBIA â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TRAF2 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
NFKB1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
MAP3K7 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 24911653 11477091 17301840 18180283 19909372 15125833 24699077 17363905 16356855 18641653 24403530 18079694 18223652 14514672 17496917 19531477 20300203 11325957 21133840 21232017 18264787 9744859 10391247 16799562 15836773 10702308 23109003 12620219 14633987 17363973 19161412 22941947 23681101 17047224 29145629 11280761 16301747 15082531 26192618 14660645 20038579 24958845 15327770 20164171 11460167 16603398 21041997
TANK IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 19854139 25861989 17468758 20484576 12133833 16189514 21419663
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
CYLD IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21988832 15341735 15870263 22990857 12917689 12917691 16627981 20932475 26802121 12917690
IKBKG NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 17145710 7862124 11087742 10602462 16818647 8657102 16965765 22435544 11064457 24369075 10880512 7739562 14743216 16319058 7878466 16126728 10329646 15836773 16177806 21217772 16153868 10195894 12514169 18617513 15371334 16493424 17706453 15145317 10723801 15870263 7796813 17468758 16603398 17965022 11830587
IKBKG NFKBIB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 15836773 14743216 15145317 17072322 10723801
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
IKBKG NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
TANK IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
TRAF3 IRF7 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
RELA IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
NFKB1 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
IRF7 IFNA14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10938111 19349300 15699120 11303025
IRF7 IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21670437 10933732 12077266 11473119 17785777 9877175 10938111 19798431 11303025 12242290 16612387 16251417 21940674 15265881 12138184 16175599 19349300 10692430 27012395 11162841 17702615
IRF7 IFNA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10938111 11884139 9786932 19557165 16014964 16380379 17785777 9877175 24185615 10692430
IRF7 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 22547704 24532789 12604599 15355347 16186222 12915551 16014964 22065573 19176627 23906644 17785777 22698399 17236232 9877175 10938111 11303025 19557165 21994549 10848607 20637800 19349300 14729983 10692430 20581830 11846976 20483755 12821121 19570869
IRF7 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23405030 20483755 16253303 24701034
IRF7 IFNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10938111 11473119 19349300 17236232 10692430
TRAF6 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22095711 18710948 21743479 30927622 15361868
TBK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 17599067 9786932 15210742 22787218 26712804 16127453 12702806 15367631 12692549 16380379 17706453 16199137 16914100
IRF3 ISG15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19367472 8524823 12604599 9446577
TRAF6 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
MAP3K7 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12589052 17965022 15692051 17947236
MAPK14 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14580335 16410802 8622692 8668171 9724653
MAPK14 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14970175
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
TANK TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20562859 21988832 21903422 8710854 12005438 14743216 10581243 16713569 23007157 10759890
TANK TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16127453 17568778 27035970 25409927 23286385 18307994 24488098 21419663 21988832 21903422 15210742 14743216 16189514 19820708 21931555 10581243 23007157 17823124 17468758 17327220
TRAF2 TNF â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 TNF â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF TRAF3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7639698 25152365 19815541 8702708 7544915
TNF TRADD â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10925299 11003656 11112697 11274345 11279185 11280761 11438547 11460167 11875494 12531547 12646658 12811837 1330325 1431106 14607933 14625680 14660645 14730360 15099563 15310755 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 21920725 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26801188 26972597 28574505 28765050 8663014 8910423 9488730
TNF FADD â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 TNF â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF TRADD â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10925299 11003656 11112697 11274345 11279185 11280761 11438547 11460167 11875494 12531547 12646658 12811837 1330325 1431106 14607933 14625680 14660645 14730360 15099563 15310755 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 21920725 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26801188 26972597 28574505 28765050 8663014 8910423 9488730
TNF FADD â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TNF TRADD â—¼   ENZYMATIC_REACTION ✅ 65.0 1.0 ACSN 10925299 11003656 11112697 11274345 11279185 11280761 11438547 11460167 11875494 12531547 12646658 12811837 1330325 1431106 14607933 14625680 14660645 14730360 15099563 15310755 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 21920725 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26801188 26972597 28574505 28765050 8663014 8910423 9488730
TNF MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
RELA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 136.0 1.0 Omnipath 26596471 17707233 20817730 12686724 27075886 21765477 21537341 19530226 17390058 18077329 15064230 20617556 8805669 17351769 23335080 21573233 17292554 16285952 9916895 11749970 7895918 17496784 12628924 23857586 12657243 15857826 12471036 11259437 16433741 9831247 20237317 15465827 26023919 22661093 10748079 15013838 17350185 10754326 15470505 11827962 20139176 26408955 22901690 18772140 21108432 22742857 23195252 18362169 24012417 11312646 17442180 9281604 10079106 11297551 15081318 22718766 24908318 8219230 26004152 11094063 11490006 9916692 16483936 18057724 16569682 22138107 18467438 20547752 22723832 19846753 17407192 20221401 19854828 20534538 7876168 16707469 12117498 20544543 23178569 15812247 21138578 12610112 25888873 16916598 16040075 28039105 14749357 20066113 19285436 25161822 22388040 14960579 20195282 16199883 15543947 23971673 10551799 11290773 22798670 22021035 20722069 20221720 27338466 19385047 12058956 26997758 25690886 7624137 20686703 26114754 14976218 10485496 17607667 8622636 11007957 18285351 10837498 11739517 18719026 17268554 17085785 17142966 10963848 9742085 23042817 27534992 10553096 26516703 20696864 10201927 16850160 8679226 21098092 20097764 9129150 17082635
TNF RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 15192014 27329558 22240205 15833743 19351843 28187781 15841081 28107185 28373828 26999213 24386331 24957606 26179215 21572963 18258304 28317833 29441018 10722927 19596989 28423685 12881425 25118327 24036851 28089769 21904602 24141032 10938077 30201812 20691659 24166907 19789307 19393267 22768286 26310932 19411070 23789107 28790310 29708974 20507904
TNF TRADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 12887920 19287455 15485837 32196115
TNF NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19053972 24083678 25215581 29088783 24386331 25888769 20460401 16866128 19934328 9363938 24349153
TRAF6 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
CYLD TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12917691 12917689 16230348 29933112 18382763
TRAF6 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15836773
TRAF6 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 7862124 7739562 11087742 10195894 7796813 12514169 7878466 8657102 16493424 17965022
TRAF6 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16260493 15691841 15620648 15327770 10195894 16186825 16493424 17965022 10094049 10837071
TRAF6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 19675569 17947236 19843958 10882101 19521662 11259596 17079228 28024152 31885808 19112497 22924441 10094049 27501752 18922473 11518704 11809792 16517750 19232515 10702308 16410796 14633987 19820695 22851693 10921914 18758450 12496252 12609980 21822258 12242293 25963657 24434549 27249171 22643835 21245467 17965022 26038599
TRAF6 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10346818 17965022 15692051 17947236
TRAF3 IRF3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
IRF3 STING1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 12133833 15210742 22394562 16281057 18818105 16306936 19926846 19776740 22579474 19433799 24560620
IRF3 IFNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10938111 11473119 12821121 19349300 24185615 10692430
IRF3 IFNA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11846978 11884139 12242290 9786932 9707562 12821121 16380379 17785777 9446577 10692430
IRF3 IFNA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20638368 19349300 18851954 12242290
IRF3 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16253303 19541850 23405030 20483755 18691624 16490936 12821121 24257594
IRF3 IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15741273 15331713 10048763 10933732 11473119 8524823 9891032 17785777 19193793 9877175 22593165 10938111 11303025 12242290 21795596 24278020 23028052 19349300 10692430 27012395 11162841 24535579 12821121 16641293 20047764
IRF3 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 84.0 1.0 Omnipath 19108859 22911767 20453844 22684309 15857993 17540767 16699525 9891032 24185615 12885884 16125763 19349300 20581830 11846976 20610716 16954376 23911869 9707562 12821121 18851954 26483348 23096996 12604599 12829834 22065573 19176627 9649509 20375222 24180280 27481269 18539711 21492741 19570869 20048166 16641293 20304918 15955070 25531393 18641315 19153231 24257594 20130065 16186222 15699120 12077266 17785777 17243100 22285490 9877175 11303025 22417706 23843640 21148557 18225953 17692882 21281747 11222729 9541017 20660350 21228327 17652396 18614628 19541850 20083668 24532789 22902624 18272195 17079289 21632562 17079305 17496231 22083261 10938111 19846511 10848607 17845078 9446577 10692430 18309294 20483755 17947522 24656046 17296604
IKBKB IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25070846 20604809 9566918 14703513 19153595 27992402 18272581 16914100
MAVS IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17020950 25636800 21903422 16153868 22750291
MAPK8 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19153595
TBK1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 24549848 18583960 22072751 16380379 26811330 16127453 17618271 23478265 19153231 12692549 28618271 17599067 22388039 15841462 25636800 21903422 15210742 33990776 20532218 16699525 20170763 30842273 12702806 16306043 17018283 20628368 16914100 33411856 23746807 28159912 16394098 18356163 22904301 34379517 22810896 14703513 22750291 27548204 29800227 22079989 24056301 14679297 17706453 20511230 24396068 19211767 18440553 16281057 12524442 16625202 9463386 19893624 18636086 15749911 18818105 27125670 24807708 15695821 9566918 30496178 17526488 19656901 23028469 32351706 24371060 15367631 16199137 25803835 24622840 16155125
RNF125 IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17460044
RNF125 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17460044
CASP8 FADD â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RIPK1 FADD â—¼   PHYSICAL_INTERACTION 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
TRAF2 FADD â—¼   PHYSICAL_INTERACTION 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
FADD CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD TRADD â—¼   PHYSICAL_INTERACTION 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD ATG5 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11003656 11583996 15325588 16498403 17462996 20531300 22362782 23377657 23725295 23787782 24070470 26587781 26972597 27984721 28574505 9488730
RIPK1 FADD â—¼   SHARES_COMPLEX 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
TRAF2 FADD â—¼   SHARES_COMPLEX 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
FADD CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
FADD TRADD â—¼   SHARES_COMPLEX 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD ATG5 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 11003656 11583996 15325588 16498403 17462996 20531300 22362782 23377657 23725295 23787782 24070470 26587781 26972597 27984721 28574505 9488730
TRAF2 FADD â—¼   ENZYMATIC_REACTION ✅ 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
FADD MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
MAP3K1 FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11034606 10640736 16061179 15001534
TRADD FADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 8565075 14744432 12911633 21760970 9430228 21724995 21741934 12796506 10911999 20203691 23955153 32296183 12107169 11112409 11464215 8681376 12887920 24686082 21183682 18545270
FADD CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 82.0 1.0 Omnipath 22864571 17145710 11717445 19524512 34591612 15280356 17047155 27552911 12911633 25043603 21458669 11788820 19176810 21525013 21988832 22179575 25939870 12702723 21737330 21741934 26437781 25911380 9228018 21785459 20829884 23972990 21620750 12220669 9774341 17159907 10521396 27321185 17290218 27560715 20103630 24098568 20203691 14612908 8681377 18485876 12107169 15659383 22421964 20448643 9343261 20125124 8681376 12887920 19060883 21737329 23142077 22173242 26972597 22274400 19935698 16410793
FADD ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15778222
FADD CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 16585540 17145710 15069192 12887920 9045686 11717445 9228018 20829884 15659383
FADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 16585540 22864571 26733177 11002422 11854271 19524512 21458669 21525013 21052097 26865630 21741934 23972990 21620750 26186194 27560715 24098568 20203691 16227629 32296183 18485876 32024820 22890322 11464215 21737329 12887920 21183682 19524513 26972597 19373245 22848449 24577083
NFKB1 NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 1829648 21725609 23178297 23572150 8096091
IKBKB NFKBIA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RELA NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18204072 17876798 24083678 15499023 25759022 23422506 12859951 7775482 11744993 22723832 23450368 11060311 12885753 18981184 9250151
NFKB1 NFKBIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17876798 15499023 17709515 7775482 11744993 10454561 11060311 12885753 9250151
NFKB1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 25609649 7862124 1340770 16210649 16970925 21719482 9738011 9865693 10497169 8657102 9572494 9315679 21988832 8887676 10329681 1829648 14743216 17003112 11313474 20558726 26496610 7867065 7891711 10837071 7831327 15836773 26186194 11571291 15214841 17561400 16846590 9566883 8096091 15371334 7479976 11020244 9426183 16493424 15145317 8631829 20237821 20980497 16513645 9597130 7479848 7739549 7628694 10655476
TBK1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 10783893 9721103 16007147 12138192 7796813 12403772 10990461 10421793 11815618 8657102 10398585 8601309
RELA NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 134.0 1.0 Omnipath 17145710 15657065 11801607 25609694 15226358 17003112 9057089 26496610 19219072 23850221 7831327 12927781 16683270 17301240 17561400 9566883 10391945 8887633 16209943 21719482 10066434 8657102 10581242 29734393 21988832 12419806 14743216 16105840 15671248 9751059 9990853 25759022 10498867 8246997 7878004 11020244 9426183 15845455 26476452 23563313 16951195 25520503 9694722 11287411 10329681 15799966 17612295 24457201 10085161 10837071 10969074 11571291 9573251 15214841 16846590 20065107 7479976 24248593 8887627 15145317 16493424 9135156 24634218 7479848 15024091 14636585 26463447 7862124 1340770 22081069 8139561 27923823 16970925 9738011 9865693 9572494 11231305 14685242 20797629 11313474 16226509 14690596 22022389 21217772 26186194 30213788 15371334 8978697 20980497 7739549 7628694
CHUK NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 113.0 1.0 Omnipath 17145710 15922746 11087742 18074035 12626540 11527961 9244310 11809792 15836773 16177806 9721103 18501560 11923072 17706453 9509763 10723801 11858955 10421793 25133483 10398585 9346484 9346241 21765415 8657102 16737960 9315679 9252186 21490922 16219905 14743216 20484017 10329646 18922877 10882136 16153868 10195894 14751757 16007147 7796813 17053167 9632633 15856023 17965022 10783893 10602462 23602409 27682876 10469655 16965765 15084594 16493072 11095741 12138192 10723127 15210742 10329681 7878466 26930276 9914500 9520446 12514169 12403772 10527519 15145317 16493424 9135156 16023083 12637324 10593898 14636585 9214631 7862124 10074115 15389589 12486103 9891086 8601309 10880512 7739562 16286467 17379600 23109003 9689078 15371334 10733566 29145629 11042193 23970940 10085062 17468758
IKBKB NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 164.0 1.0 Omnipath 18593939 17145710 18375836 11087742 16793322 11527961 28086098 21232017 12429743 21423167 17693123 21399639 15836773 16177806 9721103 29139553 9271416 17561400 11923072 10889159 17706453 10723801 12791687 11858955 22037600 16365431 10421793 25133483 10398585 9346484 9346241 11158290 18539148 23328071 15574499 21765415 16818647 8657102 18202307 16737960 9315679 21490922 9252186 20001801 15919917 16495515 11368781 16291755 24386391 14743216 25759022 10329646 10882136 16153868 10195894 14751757 18981174 10807933 16007147 7796813 9632633 15856023 17965022 25753787 10783893 10602462 27682876 16965765 15084594 19196987 17322026 12138192 10723127 15210742 16319058 15217903 15218526 7878466 9914500 17367806 9520446 15214841 16846590 12514169 18657515 12403772 10527519 15145317 16888014 16493424 17047224 9135156 15024091 16023083 10593898 14636585 22579987 9214631 24911653 7862124 10320352 16970925 23707515 9346485 12949498 17363905 12486103 9891086 8601309 10880512 7739562 16286467 23109003 9689078 25595906 15371334 16285893 11356195 29145629 23970940 10085062 11815618 17468758 17615396 24586253 17072322
CHUK MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
TRADD MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
IKBKB MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
PPP2CA MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18299321 17079228
MAP4K4 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 9890973 10807933
TRAF2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12547194 20038579 14633987 14743216 17384642
MAP3K7 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 14960582 16893890 15836773 33895773 12547194 25241761 24911653 2547194 9742107 18949366 11274345 20200282 20194509 10094049 18855897 10187861
MAP3K7 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 24911653 11129660 25195736 16006187 16260493 15502405 14530355 10779355 28159912 10094049 10837071 15836773 25659581 10195894 9689078 17363973 10807933 15214841 16186825 16493424 10022904 18316610 10187861 12547194 33895773 28475177 16301747 15691841 15620648 15327770 29748387 19632174 11460167 17965022
MAP3K7 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15692051 17947236 11865055 17965022 17186025
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
RIPK1 TRADD â—¼   PHYSICAL_INTERACTION 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TRADD â—¼   SHARES_COMPLEX 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
RIPK1 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TRADD â—¼   ENZYMATIC_REACTION ✅ 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
TRADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12887920 24735611 20203691 21724995 8612133 21741934 16603398 21119000
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
CASP10 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11002417 16186808 12887920
CASP8 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 11002422 34389694 19524512 8657102 17047155 10469655 21458669 21419663 21525013 12842894 18570872 21741934 10521396 11002417 12884866 20203691 22421964 11042193 20125124 12887920 12215447 19935698
RIPK1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11369754
TRAF2 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 TRADD â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRAF2 CASP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15024054 20696707 19278658 10837247 19416807 21235526
TRAF2 TRADD â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRAF2 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 CHUK â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
TRAF2 IKBKB â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
NFKB1 TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15723831 15041463 19392652 18990758
RELA TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15041463 19392652 21573233 15723831 9733516
CYLD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12917691 23405219 17851586
TRADD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 8702708 8565075 14585074 16713569 27383048 18621737 14743216 12796506 21741934 11181075 21119000 10911999 20203691 10892748 23955153 11112773 18439848 32296183 15485837 12887920 12517920 19815541 11479302 9020361
TRAF2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 12887920 20203691 16227629 21741934 17047155 22421964 30054040 11340079
TRAF2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15725726 12547194 11359906 25241761 20449947 9244310 16713569 23007157 10795740 24323043 19150425
TRAF2 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 27387502 15725726 12547194 11359906 25241761 20449947 16713569 18362886 23007157 10795740 21119000 19150425
TRAF2 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10346818 17145710 25241761 16636664 10755617 18635759 25260751
RELA CXCL8 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15079071 15536066 17550372 19171876 23430059 8383323 9743347
RELA CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 129.0 1.0 Omnipath 12820969 24337575 15289496 9405619 9698090 20038977 15057743 21665565 24260304 10817569 14631383 10969814 15005855 19668231 16325549 19732956 8207232 18281166 27856305 23894194 9388261 26340924 10975857 10745031 20194077 10928981 16553947 17565687 16764699 22848596 15531761 16105834 16803583 9510190 15355994 18221537 12643600 20053934 11716760 8617886 12218154 12707271 23637609 27076634 8878392 17917246 12163591 16829531 16818736 14670967 12038622 15958549 18362169 8413215 19734226 23386688 11297551 15950427 17362989 16455661 27371733 11953364 8413306 18074095 11973337 18786178 19376732 19837667 17276517 15517885 11342414 18669446 7876168 15350531 14645117 22891766 18034886 11564889 12748173 17586662 18996370 15223809 17041011 12485925 16004996 15079071 21343296 26618242 18435575 17636245 22340043 19173296 24634218 11120852 10477716 21343177 12058956 17045242 19786024 24048734 24770886 10202011 18309103 11864912 21131967 19064995 10530453 12716652 16418726 28283022 18723827 17040605 21255844 15615716 17932106 19966855 20696864 15387324 21451502 15722553 15879558 12855659 12883201 15688424 18045535 10506755
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
ATG5 CASP8 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
ATG5 ATG12 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 ATG12 â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 22093031 22166994 23030059 23301705 23725295 24070470 24257061
ATG5 CASP8 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11003656 15325588 17462996 20531300 23725295 24070470 26587781 26972597 28574505 9488730
ATG12 ATG5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11825910 20562859 17145710 12890687 17353931 22342342 9759731 9852036 23202584 11265251 12207896 12482611
TRIM25 CASP8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
DDX58 CASP8 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
CASP8 TRIM4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
CASP8 RNF135 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
CASP8 IFIH1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
TRADD CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 15173123 20125124 12887920 10521396 20203691 21741934 14585074 17047155 22421964 19935698 11788820
CASP8 CASP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 22864571 17159907 17145710 12887920 11832478 11717445 21737330 15280356 12198154 3031469 15659383 170210 8962078 22421964
CHUK RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
CHUK NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
CHUK MAP3K1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9008162 19666475 9689078 12221085
CHUK NFKBIB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
MAP3K1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18182252 9819420 9008162 10713178
MAP4K4 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20685151 10229185 9520446 23915189 26948423
CHUK CYLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19481526 24614225
CHUK RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 15611276 22110409 19609947 10521409 20863851 20051109 20363318 12767944 26999213 12842894 21903422 19110719 15858576 16382138 22155370 23894194 16046471 15128824 21569639 16846590 8246997 15485852 25341660 15494311 11983155 15980040 15489227 15849198 14636585 23343355
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
CHUK NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 12482991 19442713 14743216 15494311 11976329 15489227 16382138 16713569 10022904 10469655 27554194 11158290 11297557
CHUK NFKBIB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 17145710 8657102 15084594 9315679 9252186 14743216 9278383 9914500 15836773 9721103 23109003 9689078 15145317 10723801 29145629 9135156 10593898 14636585 17072322 29695914
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
IKBKB RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RELA IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 12820969 14688340 20221401 11058167 10657616 10940886 19122653 18690006 11792125 19624579 17982049 9464836 17924060 7565674 14976188 15251981 12077291 17579043 24012417 19299558 16166378 12517966 17635610 24184907 15270850 20876114 9808189
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
RELA IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14568984 17982049 17579043 20876114 19122653 22070873 18690006 19164128 19185846
RELA IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7957928 15331713 9446577 8035474
RELA CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23932714 20164184 15226358 16253303 25199798 16982926 19342664 10756005 23740952 17449583 16818736 19929594 22030901 19479051 24257594 21249144 24701034 20833730
RELA IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23932714 15955070 22547704 19570999 10074115 21209118 17079305 7799921 17496231 15699120 12077266 8035474 17785777 12005436 24185615 10848607 16125763 9446577 20855868 24656046 23857586
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
PPP2CA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11591705 12842894 17188031
IKBKB RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 135.0 1.0 Omnipath 15280197 17785205 27329558 22110409 22753932 22205033 21765477 15611068 18519641 15858576 25241761 33579825 23536830 28122346 19393267 34556881 24442433 14560022 15192014 21242976 16840782 19609947 33789981 10521409 26826124 21492457 19110719 23303310 16105840 22212641 26587973 34219129 15210811 16046471 11359840 27626700 15128824 28416608 17178723 21674813 17362989 28737909 19377466 15980040 16407239 15849198 20507904 26082493 15557193 34082140 21798539 26267322 29363544 12767944 20224721 26307684 12842894 17108032 26170389 24336331 27315556 31980577 11259436 34380537 20872791 21674474 15465828 15994321 17548605 26603838 16148147 25136068 33914760 26569329 22234699 17012367 14636585 22039465 32123095 15212693 27466442 33883226 15611276 22081069 19197368 17070014 20051109 26693062 14963024 33971703 28381553 33459422 27244888 18544167 18922932 20188669 15485852 20696864 22689577 17982102 20410276 15489227
TBK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 12842894 17562815 15128824 15485852 10521409 15489227 15849198 14560022 19958770 12767944
RELA NFKBIB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 22081069 10497169 12672800 21988832 14685242 14743216 16189514 16226509 26186194 11571291 10498867 15371334 8816457 8887627 15145317 9135156 16513645 9597130 14636585
NFKB1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20164184 16253303 17274000 20579762 16982926 19342664 10756005 16818736 19929594 19479051 21249144 24701034
TRADD MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRADD MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
IKBKB MAP3K1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9008162 19666475 9689078 12221085
MAP4K4 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9712898 8824585 23331499
MAP3K1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9819420 9008162 16286467 9689078 16285893 9520401
MAP3K1 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12228228 9405400 25241761 10465784 15757900 15299005 14500727 21152872 26538579
IKBKB NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
NFKB1 IL12A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 14568984 11602633 17982049 17579043 15871905 18690006 19164128
NFKB1 IL12B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 14688340 11058167 10657616 10940886 18690006 11792125 17982049 9464836 17924060 7565674 14976188 9234715 12077291 9497375 17579043 19299558 22427889 16166378 15270850 9808189
NFKB1 IFNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 15955070 17079305 7799921 17496231 15699120 10074115 20855868 24656046 10848607 12077266 8035474 17785777 20048166 21209118 16125763 12005436 22427889 21343618
NFKB1 IFNA13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7957928 15331713 8035474
NFKBIB NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17145710 15836773 11571291 16513645 9597130 23109003 14743216 12670396 10497169 15371334 7867065 8816457 15145317 15084594
IKBKB NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 57.0 1.0 Omnipath 31598684 11976329 16713569 10469655 29485707 26999213 12842894 10835356 27187478 27402796 18782567 27554194 12482991 25241761 10022904 15199157 19519322 15489227 19250910 15212693 11158290 11297557
IKBKB CYLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19481526 24614225 15870263
CYLD DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18467330 18636086
IKBKB NFKBIB â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
PPP2CB IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19607706 17188031
TBK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10783893 21903422 21138416 10195894 14743216 16207722 10022904 14560022
MAVS IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 16177806 16153868 21903422 17468758 18207245
IKBKB NFKBIB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 10320352 9346485 8657102 15084594 9315679 10723127 14743216 28086098 15218526 9278383 11470788 9914500 15836773 9721103 23109003 9689078 15145317 9520401 10723801 17047224 29145629 9135156 10593898 14636585 9346484 17072322 9346241
TRAF3 TBK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12692549 15210742 16306936 16281057 14530355 17526488 17047224 14703513 23453971
OTUD5 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17991829
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
DDX58 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17020950 16306936 16858409 21844353
TRAF3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27135603 15210743 16127453 15210742 16306936 12702806 23986588 22792062 16177806 20389019 17991829 20174559 16858409 23717208 34084167 22330071 17468758 17327220 24622840
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
DDX58 TRIM4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19017631 20403326 24755855 19484123 17392790
DDX58 CASP10 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
DHX58 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17190814 16116171 17020950 16210631
TRIM25 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20406818 30902577 20818395 24478431 34471099 23950712 34452305 34529741 18353649 35075101 18948594 27122586 32513696 17392790
RNF135 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19017631 23950712 19484123 35089988
DDX58 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16177806 17020950 15210742 15210743 23950712 16306936 16127453 17468758 16281057 12702806 17327220 16858409 21419663
DDX58 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 20554965 16127453 33372174 20007272 35075101 21419663 16585524 20406818 19052324 17020950 21903422 19164550 24478431 17190814 16713980 18200010 18948594 19193793 16177806 34544279 16153868 23843640 16785313 16301520 21844353 16125763 19036819 18977754 21102435 33976430 22301138 17709747 21200404 29263274 26494172 23499489 18207245 19881509 22844514 20080758
TRIM25 CASP10 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
RNF135 CASP10 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
CASP10 TRIM4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
CASP10 IFIH1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18761323 16618810 11717445 12884866 16585540
IFIH1 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16177806 17020950 15210742 15210743 16306936 16127453 12702806 16858409
AZI2 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 21903422 19820708 14743216 21931555 14560022
MAVS TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 21813773 15210743 16127453 33372174 17020950 25636800 21903422 15210742 16753195 16306936 12702806 24643253 16177806 27419230 16153868 16858409 29743353 17468758 17327220
TBK1 STING1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 25254379 22579474 24929887 24119841 26199418 25815785 27857881 21074459 33723219 21903422 33906974 29899553 30018345 29241549 23542348 30193098 19416887 18818105 22394562 29202128 33789998 19433799 18724357 24622840
IFIH1 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19416887 22301138 17600090 17020950 19052324 21903422 16410796 16785313 16713980 23499489 16127453 33372174 16125763
MAVS STING1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19416887 18818105 20080758 20019757 22312431 22844514 23542348 18724357 24622840 22911572
MST4 PDCD10 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PDCD10 STK25 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TRIM25 TRIM4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19017631 20403326 24755855 19484123 17392790
TRIM25 RNF135 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19017631 20403326 24755855 19484123 17392790
IL12A IL12B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 10779781 10899108 8943050 7527811
RNF135 TRIM4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19017631 20403326 24755855 19484123 17392790